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Israeli and U.S. forces launched a series of air strikes on Tuesday that struck Tofigh Daru Research and Engineering Company, one of Tehran’s largest producers of anaesthetics and anti‑cancer medicines. The state‑run firm, owned by the Social Security Investment Company, saw its drug‑production line damaged, according to an official post on X. In the north‑western city of Zanjan, a separate strike hit the Husseiniya Azam, a Shia congregation hall adjacent to a mosque. Iranian Red Crescent teams rescued two people from the rubble; one of the victims died and several others were injured. Further attacks were reported in the western province of Kermanshah, where a civilian contracting company in Qasr‑e Shirin – a border town with Iraq – was hit. One person was killed and eight injured, the Mehr news agency said. Heavy bombing was also confirmed in Isfahan, a strategic hub for Iran’s defence industry and home to key nuclear facilities such as Natanz. Local officials indicated that the strikes may have targeted “military sites,” though the exact locations and damage assessments remain unclear. Iranian officials condemned the operations. Former foreign minister Javad Zarif denounced the targeting of the pharmaceutical plant as a deliberate attack on a medical facility, calling the aggressors “desperate” and accusing them of “diabolical delusions.” Governor‑level security official Akbar Salehi echoed these concerns, noting that the strikes appeared aimed at military installations without specifying which ones. The broader conflict has already claimed 1,937 Iranian lives since the joint U.S.–Israeli campaign began on 28 February, while 20 Israelis have been killed. Recent Israeli interceptions using the Iron Dome and David’s Sling systems have limited damage on Israeli soil, but impact sites were reported in Tel Aviv, Bnei Brak and Petah Tikva. Amid the escalating violence, diplomatic channels remain active. U.S. Secretary of State Marco Rubio told Al Jazeera that communications between Washington and Tehran continue, primarily through intermediaries, and that the U.S. aims to achieve its war objectives “in weeks, not months.” Pentagon chief Pete Hegseth added that negotiations to end the conflict are “very real, ongoing and gaining strength.” Iran’s Islamic Revolutionary Guard Corps (IRGC) claimed a retaliatory strike, saying it hit an Israeli container ship in the Gulf with a ballistic missile and that Iranian drones targeted a group of U.S. Marines near a UAE military base. Public sentiment in Iran has turned sharply hostile, with pro‑state demonstrations erupting in Tehran as citizens protest the continued air raids. The atmosphere, described by Al Jazeera’s Tohid Asadi as a “cloud of mistrust,” reflects growing frustration over diplomatic dead‑ends and the relentless cycle of attacks.

United States Senator Marco Rubio has made a provocative statement regarding Iran's military capabilities, declaring that Iran's ability to launch missiles must be destroyed. The remark comes amid heightened tensions between Washington and Tehran over Iran's ballistic missile program.Rubio's statement reflects a hardline stance on Iran's military capabilities, suggesting a potential shift in US policy toward more confrontational approaches. The senator's comments indicate strong support for military action targeting Iran's missile infrastructure, which has been a point of contention in US-Iran relations for years.The missile program has been a key component of Iran's defense strategy, with officials in Tehran consistently maintaining that these capabilities are for defensive purposes and not negotiable. Rubio's statement may signal increasing pressure on Iran from US political circles regarding this aspect of their military development.

The conflict between the US and Israel against Iran has entered its 31st day, with overnight strikes hitting Tehran and other cities, targeting power infrastructure in the Iranian capital and causing a blackout that has since been restored. US President Donald Trump has stated that he wants to "take the oil in Iran", while Tehran has accused Washington of plotting a ground attack despite publicly pushing for a negotiated deal. Trump also mentioned that he is "pretty sure" a deal with Iran will be made. In a diplomatic effort, Pakistan is set to host meaningful talks in the coming days, with the Pakistani Foreign Minister stating that regional foreign ministers discussed ways to bring an early end to the war. The conflict has spread to other regions, with Saudi Arabia intercepting five ballistic missiles heading towards its Eastern province, and Kuwait reporting an attack on a service building and electric power plant, resulting in the death of an Indian worker. The economic impact of the conflict is significant, with Brent crude prices rising 2.98% to $115.93 a barrel, and Asian markets experiencing a decline, including Indonesia's main stock index and Malaysia's FTSE Bursa Malaysia Top 100.

The price of oil has surged to $116 a barrel after Donald Trump's comments on seizing Iranian oil, sparking concerns over a potential escalation in the Middle East conflict. Brent crude, the international benchmark for oil, rose by 2% in early trading on Monday.Trump told the Financial Times that his 'favourite thing is to take the oil in Iran,' which led to a significant increase in oil prices and a drop in Asian stock markets. Japan's Nikkei fell by 3%, while the South Korean Kospi dropped 3.4%. Hong Kong's Hang Seng index shed about 1%.The conflict in the Middle East has escalated with the arrival of 3,500 US troops and Houthi rebels in Yemen firing ballistic missiles at Israeli sites. This has led to concerns over a potential disruption in oil supplies, causing natural gas prices to increase in Europe.Analysts warn that if the conflict doesn't end quickly, crude could rise to $150 or even $200 per barrel, which could lead to a global recession. The UK's Keir Starmer is set to hold talks with bosses from Shell, BP, and Equinor to discuss emergency measures to contain the crisis.The war in the Middle East has driven Brent crude to its biggest monthly gain ever, up by 59% since the start of March. Industry figures have warned of potential temporary shortages at petrol pumps in the UK due to the conflict.

Iran launched a significant attack on the Prince Sultan Air Base in Saudi Arabia on Friday, wounding at least 15 American soldiers, with five in serious condition. The assault involved at least six ballistic missiles and 29 drones.The base, located about 96km from the Saudi capital Riyadh, is operated by the Royal Saudi Air Force but also serves as a critical location for American forces. The injured US troops were inside a building at the base during the strike.According to reports, the Iranian attack resulted in the destruction of one refuelling aircraft and damaged three others, putting them out of service. Satellite images published by Iran's Press TV showed significant damage to several aircraft at the airbase.This incident marks a continuation of the escalating conflict in the region, which began with a joint assault by Israel and the United States on February 28. Iran has been conducting retaliatory attacks on Gulf nations it accuses of serving as a launchpad for US strikes.The conflict has seen significant casualties on both sides. At least 13 US military service members have been killed since the war on Iran started, with over 300 American troops wounded. Iran's government has not released an updated casualty toll, but the US-based activist group HRANA reported 1,167 Iranian soldiers killed and 658 troops with unknown status as of March 23.The attack on the Prince Sultan Air Base is part of a broader pattern of Iranian retaliation. The base has been consistently targeted since the war began, highlighting the strategic importance of the location and the ongoing tensions in the region.

The US-Israeli war against Iran shows no signs of abatement as it enters its second month, with regional tensions escalating through multiple fronts. Yemen's Iran-backed Houthi rebels have confirmed their first attack on Israel since the conflict began, launching a ballistic missile that was intercepted by Israeli defense systems. The targeted strike aimed at Israeli military sites located in the south of the occupied West Bank, marking a significant expansion of the conflict beyond direct US-Israeli operations against Iran.In a separate development, Israel killed three journalists in a targeted strike on their vehicle in southern Lebanon. The incident highlights the growing dangers facing media personnel in the increasingly volatile region as the conflict continues to spread across multiple borders and involve various non-state actors.These developments underscore the complex and widening nature of the conflict, which has evolved beyond direct military confrontation between the United States, Israel, and Iran to include regional proxies and civilian targets.

Iranian President Masoud Pezeshkian has issued a stern warning to neighboring countries, urging them not to allow the US and Israel to use their territory to launch attacks against Iran. In a post on X, Pezeshkian emphasized that Iran does not initiate preemptive attacks but will strongly retaliate if its infrastructure or economic centers are targeted. “To the countries of the region: If you want development and security, don’t let our enemies run the war from your lands,” Pezeshkian stated. This message is part of a broader effort by Iran to prevent the escalation of the ongoing conflict with the US and Israel. The conflict began on February 28, when the US and Israel launched air strikes across Iran, resulting in the death of Supreme Leader Ayatollah Ali Khamenei. Since then, the situation has shown no signs of de-escalation, with Israel announcing daily strikes on Iran and Tehran continuing to target its arch-rival and countries hosting US military assets. In recent developments, several Gulf states have been targeted in attacks. In Kuwait, multiple drone attacks damaged the international airport's radar system, while in Abu Dhabi, strikes caused debris to fall near the Khalifa Economic Zone, injuring six people. Iran's military claimed to have struck a Ukrainian anti-drone system depot in Dubai, which it alleged supported US forces. Iranian Foreign Minister Abbas Araghchi also urged regional countries to distance themselves from the US, reiterating Iran's stance that it will not tolerate the use of neighboring territories for hostile actions. The conflict has resulted in significant disruptions across the region, with at least 15 American soldiers wounded in an Iranian attack on a Saudi airbase on Friday. The situation remains volatile, with alarm sirens activated in Bahrain and Saudi Arabia's defense ministry reporting ballistic missile and drone attacks, all of which were allegedly shot down.

Ukrainian President Volodymyr Zelenskyy has concluded defence agreements with the United Arab Emirates (UAE) and Qatar, focusing on joint expertise in countering threats from missiles and drones. The agreements were made during Zelenskyy's visit to Doha and the UAE earlier in the day. The defence pact with Qatar includes collaboration in technological fields, development of joint investments, and the exchange of expertise in countering missiles and unmanned aerial systems. This move comes as Iran continues to attack its Gulf neighbours, with Tehran insisting it targets only US assets in retaliation for the US-Israeli war on Iran. Ukraine has deployed 201 anti-drone experts to the Middle East to help Gulf nations counter Iranian drones. Kyiv has proposed swapping its interceptors for the more expensive air-defence missiles used by Gulf countries to down Iranian drones. Ukraine needs these missiles to fend off near-daily Russian missile attacks. The agreements highlight Ukraine's growing role as a leading producer of sophisticated, battlefield-proven drone interceptors. The country's expertise in downing Russian drones, which have been attacking Kyiv since the start of the full-scale invasion in 2022, is seen as a cost-effective solution for Gulf nations. For instance, Ukraine's interceptors cost around $2,000 each, compared to the $4 million cost of a Patriot missile. Zelenskyy's diplomatic tour aims to secure funding and technology in return for Middle East support. The US-Israeli war on Iran has depleted Patriot missile stocks, which concerns Ukraine as it needs these missiles to counter Russian ballistic missiles.

Yemen's Houthi rebels have launched a barrage of ballistic missiles at Israel, marking their first such attack since the US-Israel war on Iran began. The assault was announced by Brigadier-General Yahya Saree, a military spokesman for the Houthis, on their Al-Masirah satellite television. The attack targeted what Saree described as 'sensitive Israeli military sites' in southern Israel. The Israeli military reported intercepting one of the missiles. This development comes as Iran and Hezbollah continue to fire on Israel, with sirens sounding around Beer Sheba and near Israel's main nuclear research centre. Saree stated that the strikes 'will continue until the declared objectives are achieved, as stated in the previous statement by the armed forces, and until the aggression against all fronts of the resistance ceases'. This escalation follows a vague statement by Saree on Friday signaling the rebels' intention to join the conflict. The Houthis, who have controlled Yemen's capital, Sanaa, since 2014, had previously stayed out of the US-Israel war. However, they have been involved in attacks on shipping vessels during the Israel-Hamas war, disrupting commercial transit in the Red Sea. Over 100 merchant vessels were attacked with missiles and drones, resulting in two ships sinking and four sailors killed between November 2023 and January 2025. Experts consider the Houthis' entry into the US-Israeli war on Iran as 'very significant'. Mohamad Elmasry, a professor of Media Studies at the Doha Institute for Graduate Studies, noted that if the Houthis were to shut down the Bab al-Mandab Strait, the Red Sea, and the Suez Canal, it would impact two major international shipping waterways, alongside the Strait of Hormuz. Al Jazeera's Nida Ibrahim reported from Ramallah that the opening of a new front in the war is likely to raise questions in Israel about 'the viability of the operations and the way the government is conducting its war'. She expects Israel to retaliate to this attack, as seen in previous instances when Yemen joined the battle.