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A recent study has found that sperm deteriorates over time as it remains in the body, leading researchers to suggest that men who ejaculate more frequently may have better sperm quality.The study, which combined 115 human studies involving nearly 55,000 men and 56 studies on non-human species, found that the longer men went without sex, the more their sperm showed signs of DNA damage and oxidative stress, and the more tests rated the sperm as less viable and poorer swimmers.The World Health Organization (WHO) recommends men abstain from ejaculating for two to seven days before giving sperm for fertility tests or IVF, but the guidelines were designed to obtain the highest sperm count rather than prioritizing the best quality sperm.Dr. Krish Sanghvi, lead author of the study, said: "In men, the negative effects we found on sperm DNA damage and oxidative damage were large-ish, so we are confident that this is a biologically meaningful and important effect."The study's findings suggest that clinicians and couples should reconsider whether long abstinence is always good, as abstinence leads to deterioration in sperm quality.For couples trying to conceive naturally, a balance between quantity and quality needs to be struck, with abstaining for too long or too little potentially affecting sperm quality and quantity.Experts say that for assisted reproductive technology (ART) treatments, it's having the freshest, most healthy sperm that is probably more important, and that the two to seven days abstinence rule may not be as crucial when IVF treatment is taking place.

The UK government's recent announcement to make significant cuts to direct aid to Africa and the Middle East has been met with deep disappointment. This move is seen as a moral dereliction of duty, betraying the world's most marginalised, and a false economy that will bring greater instability to the world and make people less safe. The cut in aid to 0.3% of gross national income (GNI) from 2027 breaks Labour's 2024 manifesto pledge to restore development spending at the level of 0.7% of GNI “as soon as fiscal circumstances allow”. The UK is making the steepest proportion of aid cuts among G7 nations. As James Mattis, Donald Trump's defence secretary, once said: “If you don’t fund the state department fully, then I need to buy more ammunition ultimately.” This highlights the shortsightedness of cutting aid, which could lead to more conflict, famine, and persecution. The UK itself benefits materially from these investments. The recent inquiry by the all-party parliamentary group on global health and security on international health worker recruitment highlights the extent to which the NHS and wider economy rely on the skills, expertise, and partnerships rooted in the global south. The UK has saved £14bn in training costs through international recruitment and continues to depend on globally trained health professionals. Investment in global vaccination, disease surveillance, and research helps stop outbreaks before they spread internationally and place pressure on health systems. Preventing disease at source is one of the smartest investments we can make to protect patients in Britain. The situation in Somalia, on the edge of famine, underscores the importance of sustained investment in global development. Two consecutive failed rainy seasons have left 6.5 million people in crisis, more than double the number a year ago. The UK's humanitarian relief in Somalia is welcome, but the scrapping of nature funding and cuts to climate aid risk compromising its own strategy of preventing crisis before it takes hold.

As the conflict drags on, Iranians are attempting to maintain a semblance of ordinary life in the face of constant explosions and airstrikes. The days following Nowruz, the Persian New Year, are usually a time of renewal and celebration, but this year, the atmosphere is tense."More and more, people are starting to normalise this war", said Farhad, a photography editor in Tehran. "It's difficult, but we're adapting and trying to return to our daily lives as much as possible. There's no alternative. We're tired. We just want peace."Despite the challenges, some Iranians are finding ways to cope. Aylar, a 39-year-old human rights worker, paid for an expensive VPN to circumvent the internet blackout imposed by Iranian authorities so she could stay in touch with relatives abroad. She also made time for a coffee date with friends, highlighting the complexity of life during conflict.The humanitarian toll is significant, with Iran's official death toll frozen at around 1,500, but the real figure may be more than 3,000, according to the Iranian Human Rights Activists News Agency. Many more have been injured, and the psychological impact is profound.As the situation continues to unfold, uncertainty and division within Iranian society are palpable. While most Iranians oppose the war, some have welcomed it as a potential catalyst for change. The future remains uncertain, with concerns that the conflict could become a recurring reality.

Amazon Prime's latest action thriller, Pretty Lethal, brings a unique twist to the genre by featuring a group of young ballet dancers who use their skills to take down bad guys in Eastern Europe. The film, directed by Vicky Jewson, offers a fresh take on the action genre with its blend of ballet and combat. The story follows a group of American dancers, including Lana Condor, Maddie Ziegler, and Millicent Simmonds, who are on their way to a competition in Budapest when their bus breaks down in the middle of nowhere. They soon find themselves facing off against a group of ruthless henchmen, led by Uma Thurman's character, Devora. With a runtime of less than 90 minutes, Jewson keeps the action fast-paced and thrilling, making use of the dancers' skills to create a unique and entertaining fight choreography. While the script may feel a bit basic at times, the film's energy and tenacity make up for it. Pretty Lethal is not trying to be a high-brow film, but it does offer a refreshing change of pace from the usual nihilistic and smug action films. The young actors, including Condor, Ziegler, and Simmonds, deliver convincing performances as they learn to fight on the job. Uma Thurman, as the villain Devora, brings a level of hammy humor to the film, but her performance feels somewhat underutilized. Overall, Pretty Lethal is a fun and entertaining action thriller that is worth checking out.

Lisa Kudrow reprises her role as Valerie Cherish in the third season of 'The Comeback', a character often compared to Steve Coogan's Alan Partridge. Both are narcissistic figures clinging to past showbiz successes. The show initially gained acclaim for its satirical take on the entertainment industry. This season, Cherish is offered a lead role in a new sitcom called 'How's That?', which is secretly written by an AI program. The use of AI in comedy writing is a key concern, especially following the 2023 US writers' strikes. However, the show fails to effectively satirize this concept, instead opting for a more sentimental approach. The Comeback's earlier seasons were praised for their meta approach, blending reality TV and mockumentary styles. However, the latest season struggles with its format, frequently switching between mock-doc and traditional sitcom modes without clear justification. Cherish, once portrayed as a sharp-elbowed has-been, has evolved into a reformed character. She is now universally praised by those around her, making her less relatable and less humorous. The show's attempts at humor fall flat, with the AI-generated scripts producing generic and unfunny gags. The season concludes as a heartfelt paean to traditional comedy, but its lack of humor and toothless satire leave little confidence in its future. The show's shift towards sentimentality over satire is a significant disappointment.

Richie Garcia, a former major league umpire, has voiced his concerns about the impact of robot officials on human umpires in Major League Baseball. The Automated Ball-Strike Challenge System, set to debut in 2026, allows teams to challenge strike zone decisions using a system based on 12 Hawk-Eye cameras.Garcia believes that this technology will lead to the humiliation of umpires, stating, "Nobody likes to be humiliated in front of 30,000, 40,000 people." He argues that Major League Baseball is essentially saying it doesn't trust the umpire's strike zone and will instead rely on a system operated by "some computer geek" with a PhD in physics.Despite criticism, umpires have shown increased accuracy in recent years, with an accuracy rate of 92.83% last season, down from an average of 10.88 missed calls per game. The introduction of ABS aims to further reduce errors, with each team getting two challenges per game.Umpires have mixed views on the technology, with some seeing it as a way to correct egregious pitches and others concerned about the mental impact of constant evaluation. Spring training test results showed varying success rates among teams, with Philadelphia and Chicago Cubs performing well in challenge success rates.

Mark Simmons, a rising star in the comedy world, has made a name for himself with his quick wit and clever one-liners. In a recent interview, Simmons opened up about his journey as a comedian, his inspirations, and his latest tour, Jest to Impress.Simmons' love affair with comedy began when he was starting out. He devoured DVDs and videos of standups, drawn to those who dared to be different. Stewart Lee, Rhod Gilbert, Lee Mack, and Noel Fielding were among his early inspirations. Simmons' own style is characterized by his ability to craft clever one-liners and gags, earning him the title of Dave's Joke of the Fringe winner in 2024.When it comes to writing new material, Simmons has a keen eye for wordplay. He recalls a conversation with a friend that sparked a joke, showcasing his ability to find humor in everyday life. Simmons' process involves collecting notes and ideas, which he then crafts into jokes.Simmons has had his fair share of memorable gigs, including a standout performance at Glastonbury festival and a recent show at Nottingham Playhouse, where he performed to a sold-out crowd of 700 people. His show, Jest to Impress, is a celebration of silliness and wordplay, offering audiences a chance to forget their worries and have a laugh.Simmons also hosts a podcast where he discusses jokes that haven't quite landed. He shares an example of a joke that works on paper but not in front of an audience, highlighting the challenges of comedy. While awards like Dave's Joke of the Fringe are fun, Simmons acknowledges that they can be reductive, but he's proud to be the undefeated champion.Jest to Impress is currently on tour in the UK and Ireland until November 28. Fans of Simmons can catch him live, enjoying his unique brand of comedy that promises to leave audiences laughing and entertained.

Israel's parliament has moved closer to implementing a contentious death penalty for Palestinians convicted of terrorism, with the Knesset's national security committee approving the measure on Tuesday. The bill, initiated by the far-right Otzma Yehudit party, now heads to its final vote.Critics, including human rights groups and UN experts, have strongly opposed the bill, citing concerns it violates international law and discriminates against Palestinians. The proposed law would allow for executions to be carried out within 90 days of sentencing, with hanging as the specified method.The bill also proposes that those sentenced to death be held in a separate facility with restricted visitation rights. Executions would be carried out without the option for clemency, a provision that has drawn sharp criticism from opponents.International condemnation has been swift, with UN experts urging Israel to withdraw the bill, stating it would violate the right to life and constitute cruel, inhuman, or degrading punishment. The European Union's diplomatic service has also condemned the bill, emphasizing that the death penalty is a violation of the right to life.In Israel, the bill has been backed by National Security Minister Itamar Ben-Gvir, who has worn a noose-shaped lapel pin in support of the measure. However, notable opposition has come from within Israel, including from centre-left lawmaker Gilad Kariv, who has raised concerns about the bill's moral and legal implications.

The traditional cold war diplomacy of brinkmanship, characterized by carefully balanced standoffs and rules-based international order, has given way to a world in freefall. This shift is exemplified by the ever-widening conflict in the Gulf where strategic objectives remain as unclear as the potential endpoint of hostilities.Approaching a month since the United States and Israel launched attacks on Iran, the stated objectives of removing the country's nuclear threat and destroying its ballistic missile capability appear increasingly disconnected from the disproportionate impact on civilians and neighboring Gulf nations. Despite these consequences, the Iranian regime's willingness to escalate the conflict shows no signs of diminishing.The Guardian Weekly's coverage examines this critical juncture through multiple perspectives. Patrick Wintour recounts the pivotal week when global tensions reached a tipping point, while Richard Partington analyzes the long-term economic implications of a prolonged conflict, from oil price fluctuations to inflationary pressures and economic growth impacts. From South Lebanon, William Christou reports on healthcare professionals caught in the crossfire of Israeli airstrikes, highlighting the human cost of the escalating violence.Emma Graham-Harrison provides insight from Jerusalem, examining Israeli Prime Minister Benjamin Netanyahu's strategy of attempting to rehabilitate his image through what he frames as destruction of an 'axis of evil.' Meanwhile, Simon Tisdall poses a critical question: when US President Donald Trump eventually seeks to halt the conflict, will any parties be willing to heed his calls for de-escalation?Beyond the primary geopolitical focus, this week's Guardian Weekly edition explores several significant developments across different sectors. The UK political landscape features an examination of the upcoming local elections, where voter sentiment appears increasingly focused on rejecting established parties rather than actively supporting alternatives. The scientific section explores innovative approaches to addressing snoring disorders through CPAP machines, while the culture section features an in-depth interview with Dave Grohl discussing Foo Fighters, personal challenges, and grief following the loss of bandmate Taylor Hawkins.In sports, the publication celebrates the remarkable achievement of British athletes Keely Hodgkinson, Georgia Hunter Bell, and Molly Caudery, who each secured gold medals at the world indoor athletics championships in Poland, showcasing British excellence in track and field events.