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For the first time, thousands of cancer patients from Black and minority ethnic backgrounds will benefit from an enhanced genetic test offered by the NHS. The new screening expands the panel of DPYD gene variants from four to five, directly addressing a long‑standing bias that left non‑white patients vulnerable to dangerous chemotherapy side‑effects. In England, patients slated for chemotherapy undergo a genetic check that can guide dose adjustments and mitigate adverse reactions such as mouth sores, hair loss, nausea, fatigue, and, in severe cases, death. Up to 40% of the 38,000 individuals receiving fluoropyrimidine‑based chemotherapy each year experience a harmful drug reaction. Previously, the test only targeted four DPYD variants common in people of European descent, meaning many Black patients received inaccurate “all‑clear” results. The addition of a fifth variant—more prevalent among African, Caribbean and other minority groups—means clinicians can now identify patients at risk who were previously missed. Since its rollout at Manchester University NHS Foundation Trust last September, three minority‑ethnic patients have had their initial chemotherapy doses adjusted, lowering their chance of a potentially fatal reaction. Dr Veline L’Esperance, senior clinical adviser at the NHS Race and Health Observatory, called the change “tangible results for patients who have historically been left behind.” She emphasized that the update shifts the discussion on ethnic health inequality from rhetoric to actionable care. Prof Habib Naqvi, chief executive of the NHS Race and Health Observatory, described the development as a “groundbreaking outcome” for chemotherapy safety, while noting that ethnic minorities remain under‑represented in genomic research and biobanks. He warned that broader inclusion is essential for the promised benefits of precision medicine to reach all communities. Prof Dame Sue Hill, chief scientific officer for NHS England, highlighted the significance of discovering the fifth variant: “Personalising chemotherapy based on genetics can save lives and reduce harmful side‑effects, especially for patients of African ancestry.” She added that the North West NHS Genomic Medicine Service has already demonstrated the practical impact of this approach. These steps come amid broader evidence that minority patients in the UK face longer diagnostic waits, more GP visits before a cancer diagnosis, and lower perceived support during treatment. The expanded DPYD test represents a concrete effort to close those gaps and ensure equitable, science‑driven care for all cancer patients.

A comprehensive study from Denmark has concluded that taking acetaminophen, commonly known as Tylenol, during pregnancy has no effect on later autism diagnoses in children. The research, which utilized Denmark's robust national healthcare system to track more than 1.5 million children born between 1997 and 2022, including 31,098 children who were exposed to Tylenol in utero, found no significant link between Tylenol use and autism. The study's findings contradict claims made by the Trump administration, which had suggested that Tylenol use during pregnancy was a major cause of autism in children. This led to a notable 16% drop in Tylenol orders for pregnant women in emergency rooms following the announcement. However, the new study provides reassurance that Tylenol is safe to use during pregnancy for pain relief and fever reduction. According to the study, autism was diagnosed in 1.8% of children who were exposed to Tylenol and 3% of those who weren’t. A similar 2024 study in Sweden found a marginal link that disappeared after considering siblings, suggesting that autism is strongly genetic. Health officials had previously announced a label change for acetaminophen, warning of a potential link to autism, which has now been called into question. Experts, such as Jeremy Faust, an emergency physician at Mass General Brigham and a health services researcher at Harvard Medical School, have noted that the words of health officials can significantly affect behavior, as evidenced by the drop in Tylenol orders. However, Faust also emphasized that Tylenol remains one of the safest options for pain control and fever reduction during pregnancy.

World champion boxer Terence Crawford was found guilty of careless driving on Monday and ordered to pay a $75 fine stemming from a traffic stop last year that led to a gunpoint incident. The incident occurred on September 28, hours after Crawford's hometown of Omaha held a parade to celebrate his unanimous-decision victory over Canelo Álvarez in a super middleweight championship fight.Crawford was stopped by police after officers observed his vehicle driving recklessly. During the stop, Crawford's head of security informed an officer that he was carrying a legal firearm, and seconds later, another officer spotted a gun on the floorboard. With guns drawn, officers ordered everyone out of the vehicle. Crawford claimed he had leaned over to tell the officer that he also had a legal firearm, but the officer didn't hear him. Police confirmed that all occupants of the vehicle were legally permitted to carry firearms.The traffic stop led to an internal investigation by the Omaha police chief into the officers' actions, which was found to have been lawful. In addition to the $75 fine, Crawford was ordered to pay $49 in court costs. This incident comes after Crawford announced his retirement in December with a 42-0 record and 31 knockouts, making him the first male boxer to capture three unified division titles.

Monarch Collective believes that a number of Women’s Super League (WSL) clubs remain “afterthoughts” for their owners, receiving only marginal capital and expertise. Co‑founder Kara Nortman highlighted this concern during a recent interview.Last month, Monarch became the first women’s multi‑sport group by acquiring a minority stake in the Cleveland WNBA franchise, joining an ownership portfolio that already includes NWSL sides San Diego Wave and Boston Legacy, as well as German club Viktoria Berlin.Since establishing Monarch in 2023—four years after launching Angel City FC with Natalie Portman and Julie Uhrman—Nortman has held informal talks with roughly a dozen English clubs, though no deal has yet materialised. She declined to comment on ongoing negotiations with West Ham United’s women’s side, noting that finding the right English partner has proven “challenging”.Recent years have seen a wave of international interest in WSL clubs, yet many prospective investors perceive the women’s teams as a compliance tool for profitability and sustainability mandates rather than a growth engine. In the past twelve months, clubs such as Chelsea, Aston Villa and Everton have sold stakes in their women’s sides to related‑party entities, while US‑based Bay Collective recently secured majority ownership of Sunderland Women in the WSL2.Monarch’s latest $250 million funding round equips it with the capital to act when a suitable opportunity arises. Nortman explained, “If owners truly believe in their women’s team, they should invite us to ‘supercharge’ it with our cross‑sport expertise. If they only want a token boost, that’s a different story.”Beyond capital, Monarch offers advisory services. Nortman recounted a humorous encounter with fans at Crystal Palace, where a supporter asked if she was a “Wag”, prompting a light‑hearted response that underscored the firm’s community‑focused ethos.Reflecting on Angel City’s trajectory, Nortman noted that Monarch initially invested about $1 million to help the club join the NWSL in 2020. Four years later, Angel City was sold to Disney CEO Bob Iger and his wife for a reported $250 million, making it the world’s most valuable women’s franchise.Looking ahead, Monarch is broadening its scope beyond football and basketball, exploring opportunities in cricket and rugby union. The firm recently opened a London office, led by former Manchester City executive Katharine Curran, to deepen its engagement with the UK sports market.

On a recent weekday evening, a special bus tour whisked art lovers through over twelve galleries and museums that stayed open until midnight, offering a late‑night glimpse of the Abidjan Art Week programme.The after‑hours event, dubbed the Night of the Galleries, was first trialled in January 2024 alongside the Africa Cup of Nations – a tournament that Côte d’Ivoire both hosted and won – and has become a staple of the festival’s third edition, which ran from Tuesday to Sunday.Since its inception, the week has broadened its footprint, moving beyond the city centre to include venues such as the La Rotonde des Arts contemporary‑arts hub in the Plateau district and the Adama Toungara Museum of Contemporary Cultures (MuCAT) in the working‑class neighbourhood of Abobo.Local collectors are emerging in force. MuCAT has hosted the Africa Foto Fair each year since 2022, and the Marché des Arts du Spectacle d’Abidjan – the city’s answer to the Dakar Biennale – is set to launch its 14th edition later this month.A graffiti festival launched two years ago has transformed the perception of street art, with vibrant murals now adorning the façade of the La Pyramide building and several upscale hotels in Plateau.Organisers stress that the festival’s growth should be independent of external validation. This year’s roster featured artists from Cameroon, the Democratic Republic of the Congo and Mali, and the number of participating galleries more than doubled compared with previous editions.Founder Yacouba Konaté, who also directs La Rotonde des Arts, highlighted the festival’s commitment to accessibility, arguing that art should not be seen as an elite pastime.The opening tribute honoured Simone Guirandou‑N’Diaye, a pioneering Ivorian art historian whose legacy lives on through Galerie LouiSimone Guirandou, now run with her daughter Gazelle.Among the week’s highlights, MuCAT presented Murmures d’Archives, a quieter, archival‑focused exhibition that concluded with an artists’ workshop and a DJ set.In the upscale Cocody district, New York‑based artist Ouattara Watts staged a solo show at Galerie Cécile Fakhoury, drawing the Ivorian diaspora into dialogue with the local scene. Watts explained that his work aims to transcend borders, describing it as “a vision that goes beyond any map – it is the cosmos that I paint.”

Los Angeles residents are facing sticker shock over the presale ticket prices for the 2028 Olympics, with many expressing frustration over the high costs. The tickets, which went on sale for local residents on April 2, range in price from $28 to thousands of dollars.Many residents found that the lower-priced tickets quickly sold out or were unavailable for popular sports like gymnastics and track and field, leaving them with more expensive options. A 24% service fee was also added to the ticket prices, which some residents found excessive.One resident, Kathy Dorn, spent around $1,200 on tickets to watch the rhythmic and artistic gymnastics preliminaries and the sailing finals. She was deterred from buying a ticket to a swimming event due to the high price of $558 per ticket for a two-hour event.Another resident, Tony Anthony, spent $11,000 on eight tickets for track and field events, with nearly $400 going toward the service fee. He noted that the lower-priced tickets were not available during his time slot.The LA Olympics committee has defended the ticket prices, stating that most of the $28 tickets went to purchasers in southern California and Oklahoma City. They also noted that the ticket prices are meant to ensure that the Games can break even without burdening the city with costs.The high ticket prices have raised concerns among residents, particularly in Inglewood, where the opening ceremony and some events will take place. Some residents are worried that they will be priced out of attending the Games and will have to bear the burden of traffic, congestion, and noise during the events.

Conversations about mundane topics are often dreaded, but research suggests that people enjoy them more than they anticipate. A study involving 1,800 volunteers found that participants enjoyed chatting about dull subjects, such as the stock market or vegan diets, more than they expected. The findings indicate that by avoiding potentially dull exchanges, individuals may miss out on the mood boost and health benefits that come with connecting with others. Elizabeth Trinh, a PhD candidate in management and organisations at the University of Michigan, noted that people tend to underestimate how interesting and enjoyable conversations about boring topics can be. Trinh and her colleagues conducted a series of experiments to gauge how people responded to conversations on dull topics. Participants were asked to predict how much they would enjoy discussing topics they considered boring, and then engage in brief conversations about those topics. The results, published in the Journal of Personality and Social Psychology, showed that people consistently found the conversations more enjoyable than they expected. The surprise enjoyment arises because individuals base their expectations on static components, such as the topic and the other person, rather than dynamic components, like the conversation itself. Trinh suggests that people may benefit from lowering the bar for what makes a conversation worth having and reframing conversational goals. Instead of focusing on enjoyment, individuals could think about what they might learn from the conversation. Nicholas Epley, a professor of behavioural science at the University of Chicago, added that the fear of a boring conversation shouldn’t prevent people from starting one. “If a conversation is boring once you’re in it, you also have a surprising amount of power to make it better!”

Ghanaian winger Dominic Frimpong was tragically killed at the age of 20 in an armed robbery attack on his team's bus. The incident occurred on Sunday as Berekum Chelsea was returning from a Ghana Premier League match against Samartex.The club reported that six masked men, armed with guns and assault rifles, blocked the road. As the bus attempted to reverse away from danger, the robbers opened fire. Staff and players fled the vehicle, but Frimpong was struck in the head. He was taken to hospital but succumbed to his wounds, becoming the only reported casualty. The bus was carrying 30 players and officials.The Ghana Football Association (GFA) expressed profound shock and deep sorrow over Frimpong's passing. In a statement, the GFA described him as a promising young talent whose dedication and passion embodied the spirit of the league. This season, Frimpong had scored two goals in 13 appearances.This incident is not isolated; several teams in Ghana, including FC Savannah, Wa All Stars, Legon Cities, and AshantiGold, have reported similar attacks in recent years. Local police have deployed additional personnel and crime scene experts, vowing to arrest the perpetrators within the shortest possible time.

Taiwan's 'Sunshine Women's Choir' has taken the local box office by storm, but its success has been met with criticism over its emotionally manipulative tactics and lack of depth. The film, adapted from the 2010 Korean movie 'Harmony,' tells the story of Hui-Zhen, a woman who forms a choir with her fellow inmates to raise her infant daughter behind bars.The movie's director, Gavin Lin, has been accused of resorting to manipulative tactics to elicit emotions from the audience, including excessive crying and contrived plot twists. Despite its feel-good/feel-bad tone, the film's relentlessly peppy approach undermines any potential for foundational grit, critics argue.The story follows Hui-Zhen's journey as she navigates life in prison and forms a choir with her fellow inmates. However, the film's sanitized portrayal of prison life and its lack of meaningful character development have been criticized. The movie's use of showstoppers and flashbacks has also been seen as a way to avoid addressing the characters' deeper issues.Despite its criticisms, 'Sunshine Women's Choir' is set to hit UK cinemas on April 17. The film's success has sparked a debate about the role of emotion in filmmaking and the importance of depth in storytelling.