New Study Finds No Link Between Tylenol Use During Pregnancy and Autism

A comprehensive study from Denmark has concluded that taking acetaminophen, commonly known as Tylenol, during pregnancy has no effect on later autism diagnoses in children. The research, which utilized Denmark's robust national healthcare system to track more than 1.5 million children born between 1997 and 2022, including 31,098 children who were exposed to Tylenol in utero, found no significant link between Tylenol use and autism.

The study's findings contradict claims made by the Trump administration, which had suggested that Tylenol use during pregnancy was a major cause of autism in children. This led to a notable 16% drop in Tylenol orders for pregnant women in emergency rooms following the announcement. However, the new study provides reassurance that Tylenol is safe to use during pregnancy for pain relief and fever reduction.

According to the study, autism was diagnosed in 1.8% of children who were exposed to Tylenol and 3% of those who weren’t. A similar 2024 study in Sweden found a marginal link that disappeared after considering siblings, suggesting that autism is strongly genetic. Health officials had previously announced a label change for acetaminophen, warning of a potential link to autism, which has now been called into question.

Experts, such as Jeremy Faust, an emergency physician at Mass General Brigham and a health services researcher at Harvard Medical School, have noted that the words of health officials can significantly affect behavior, as evidenced by the drop in Tylenol orders. However, Faust also emphasized that Tylenol remains one of the safest options for pain control and fever reduction during pregnancy.