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Science May 31, 2026

The Pavlovian Paradox: How Mosquitoes Learn to Associate DEET with Food

A groundbreaking study published in the Journal of Experimental Biology reveals that mosquitoes can…
The Pavlovian Paradox: Mosquitoes Learn to Associate DEET with FoodFor decades, the efficacy of DEET (N,N-diethyl-meta-toluamide) has been attributed solely to its chemical properties, which are believed to either repel insects or block their ability to detect humans. However, a new study led by Professor Claudio Lazzari from the University of Tours suggests a more complex behavioral interaction. The research indicates that mosquitoes can learn to associate the scent of DEET with the presence of a blood meal, effectively turning a repellent into a lure through a process similar to Pavlovian conditioning.Experimental Evidence: From Repellent to LureThe study, published in the Journal of Experimental Biology, involved trapping mosquitoes and presenting them with warm blood that was just out of reach. The insects were simultaneously exposed to DEET. The results demonstrated a significant shift in behavior:Trained Group: 60% of mosquitoes that fed while exposed to DEET subsequently attempted to bite when exposed to the repellent alone.Control Groups: Significantly lower percentages were observed in untrained insects (17%) and those with prior exposure to DEET alone (13%).In a real-world test, nearly 60% of the trained mosquitoes attempted to bite a researcher's DEET-treated hand, whereas untrained mosquitoes universally targeted the untreated hand.Redefining Insect Control StrategiesThis discovery represents a significant shift in our understanding of how repellents work. It suggests that the reaction to DEET is not merely a chemical aversion but can be modified by experience. Experts, including Dr. Nina Stanczyk of ETH Zürich, emphasize that while the learning ability of mosquitoes is impressive, the implications for public health are nuanced. The study highlights that repellents may function differently depending on the context of the mosquito's previous interactions with humans.Future Outlook for TravelersDespite the alarming findings, experts urge travelers not to abandon DEET. The consensus is that this phenomenon occurs under specific laboratory conditions and is unlikely to happen frequently in the wild due to the variability of repellents encountered during different blood meals. The key takeaway for the future is the importance of consistent application. As noted by the researchers, the risk of association is highest when the repellent starts to wear off, reinforcing the need for regular reapplication to maintain protection.
#DEET #Mosquitoes #Claudio Lazzari
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Health May 31, 2026

Daily Pill Can Double Survival Time for World's Deadliest Cancer, Trial Shows

A groundbreaking clinical trial demonstrates that a daily pill called daraxonrasib can double survi…
The LeadA daily pill has shown remarkable results in doubling survival time for patients with pancreatic cancer, the world's deadliest form of the disease. According to clinical trial results presented at the American Society of Clinical Oncology's annual meeting, this breakthrough treatment represents a potential revolution in how we approach a cancer that has seen limited progress for decades.The Breakthrough Drug: DaraxonrasibThe drug in question, daraxonrasib, works by targeting a protein called Kras that fuels nearly all pancreatic cancers. This mechanism represents a significant advancement in treatment strategy, as Kras has been notoriously difficult to target effectively. The drug functions as a Ras(On) multi-selective inhibitor, capable of turning off the Kras protein to stop cancer growth regardless of which variant is present.Impressive Trial ResultsIn the clinical trial involving 500 patients with advanced pancreatic cancer, the results were striking. Those who took daraxonrasib lived an average of 13.2 months, compared to just 6.6 to 6.7 months for patients who received chemotherapy. This represents a near doubling of survival time, with the added benefit of fewer side effects compared to traditional chemotherapy treatments.Industry Impact and Expert ReactionsThe findings have been hailed as a "gamechanger" and "grand slam" by experts in the field. Dr. Rachna Shroff, chief of oncology at the University of Arizona Cancer Center, described the results as "landscape-changing" and "unprecedented survival." When she first read the trial results, conducted by researchers at the Dana-Farber Cancer Institute in Boston, she wept, noting the profound impact this could have on patients after 16 years of treating pancreatic cancer.Dr. Julie Gralow, Asco's chief medical officer, echoed these sentiments, calling the study a "home run" and suggesting it was actually a "grand slam" in terms of its significance.The Ras RevolutionOver 90% of patients with the most common form of pancreatic cancer, pancreatic ductal adenocarcinoma (mPDAC), have a mutation in the Kras gene. This discovery has long been considered the "holy grail" in cancer research, particularly for pancreatic cancer where the mutation is nearly ubiquitous and an early driver of cancer growth.Paula Hanford, chief executive of UK-based Pancreatic Cancer Action, called this one of the most significant developments in treatment she had ever seen. Similarly, Anna Jewell, director of services, research and innovation at Pancreatic Cancer UK, described the results as "exciting," noting that the drug gives patients "months more precious time with their loved ones."Future Outlook and ApplicationsThe success of daraxonrasib opens doors for similar treatments targeting Ras genes in other cancers. Experts at the conference noted that because Ras genes fuel various types of cancer, there is hope for breakthroughs in treating lung and colon cancers as well, with similar drugs already in development for these conditions.However, challenges remain in ensuring these promising treatments become widely available to patients. As Jewell pointed out, tragically half of all people with pancreatic cancer die within just three months of diagnosis, making the rapid implementation of such treatments crucial.
#Pancreatic Cancer #Daraxonrasib #Kras
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Tech May 31, 2026

The Future of Reproduction: 'Mind Children' and the Rise of AI

The concept of 'mind children' - AI entities that could replace biological offspring - is gaining t…
The Concept of 'Mind Children' A few months ago, an AI researcher from Europe attended a dinner party in Silicon Valley. During one of the many courses, the host addressed his guests, all of whom worked in AI. The researcher paraphrased his message like this: “Isn’t it amazing that we are the last generation of humans who will need to think about procreating biologically? We were lucky enough to be born at a time where we can simply upload our consciousnesses instead.” The Book That Sparked the Conversation The book in question was Hans Moravec’s Mind Children: The Future of Robot and Human Intelligence, which was first published in 1988, and which at the time, according to economist and futurist Robin Hanson of George Mason University, caused a big splash in a small pond – the community of robotics and machine-learning experts to which Moravec belonged. The Data Analysis Moravec’s book is more philosophical treatise than technological manual, but the central idea is that cultural evolution has long since taken over from biological evolution as the most powerful force shaping humanity. The logical extrapolation of this is that the information that encodes our future selves would soon be packed into hardware and software rather than DNA. The Impact Analysis Angela Aristidou, who studies the real-life deployment of AI at University College London, is not surprised that Moravec’s book is enjoying a revival. She says that what in 1988 might have read like science fiction – and still might to most of us – looks eminently realisable to those in the know. The Prediction Hanson shares his conviction that the revolution is inevitable, as soon as AI attains something experts agree to call human-level intelligence. “We are going to generate an explosion of things like us in the future, who will be different from us in many ways,” Hanson says. “To the extent that they have minds somewhat like ours, they are our mind children.”
#AI #Artificial Intelligence #Reproduction
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Environment May 31, 2026

Swimming Snakes Threaten Ibiza's Iconic Wall Lizards

A grainy video captured in April 2024 shows a horseshoe whip snake swimming from Ibiza to the islet…
In April 2024, a local wildlife ranger recorded a pale horseshoe whip snake gliding through the turquoise waters between Ibiza and the tiny islet of Santa Eulària, providing the first indisputable visual proof that the invasive snake can swim and expand its range across the Balearics.The First Video Confirms Snakes Swimming Between Ibiza and Santa EulàriaThe footage, shot on a minuscule island 450 metres off Ibiza’s east coast, validates long‑standing anecdotal reports from fishermen and tourists. Biologist Oriol Lapiedra of the Centre for Ecological Research and Forestry Applications (Creaf) noted that while snake sightings were common, this was “the first proper evidence” of a snake making the crossing.Captures and Projections Reveal a Rapidly Expanding Snake PopulationMore than 3,500 horseshoe whip snakes were captured on Ibiza in 2025 alone.Since 2016, over 16,000 individuals have been culled.Scientists forecast that the species will occupy 100 % of the island by the end of 2027.On the mainland, snakes rarely exceed 1.8 m in length, but Ibiza specimens have been recorded at over 2 m and weighing 2.5 times as much.Ecological Fallout: Endangered Wall Lizards Face Near‑ExtinctionThe Ibiza wall lizard (Podarcis pityusensis) was upgraded by the IUCN in October 2022 from “near threatened” to “endangered”, reflecting the mounting pressure from the snake. On Santa Eulària, researchers counted 72 lizards in 2016 but only three in 2023. Across the ten islets that once hosted unique lizard populations, many have now lost their native reptiles entirely, erasing thousands of years of isolated evolution.Future Outlook: Management Strategies and the Likelihood of Island‑Wide InfestationRegional authorities, in partnership with Creaf and conservation NGOs, are intensifying capture programmes and exploring “Noah’s ark” captive‑breeding projects to preserve genetic stock. However, the sheer scale of the snake invasion—driven by imported olive trees that provide hidden refuges—means that without sustained effort, the horseshoe whip snake could dominate the Balearic archipelago, reshaping its ecosystems for decades to come.
#Horseshoe whip snake #Ibiza #Balearic Islands
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Entertainment May 31, 2026

Maggie O'Farrell: Uncovering Family History Through Fiction

Author Maggie O'Farrell discusses how her search for a family ancestor led to her new book, 'Land',…
Uncovering Family History Through Fiction Maggie O'Farrell's journey into her family's past began with a childhood myth about an ancestor who worked on the first maps of Ireland. Years later, a hand-drawn map and an old photograph led her to discover the truth about her great-great-grandfather's role in the Ordnance Survey. The Mapper's Story O'Farrell's ancestor was a labourer and translator who worked on mapping divisions in Ireland during the aftermath of the great famine. His task was to ensure that the changes caused by the disaster were marked on the new post-famine versions of Ireland's maps. A Window into the Past The photograph showed O'Farrell's great-great-grandfather with a child on his knee, wearing a worn jacket and a low-brimmed hat. A hand-drawn map, beautifully rendered in coloured inks, revealed a tiny medallion with a red-jacketed soldier and O'Farrell's ancestor. The discovery sparked O'Farrell's curiosity about her family's history and the history of Ireland. The Impact of the Great Famine The great famine, which occurred between 1846 and 1852, had a devastating impact on Ireland, with over a million people dying of starvation or famine-related disease, and another million forced to emigrate. Fiction as a Tool for Discovery O'Farrell believes that fiction comes from what you don't know, and her book 'Land' is a testament to this. The novel tells the story of a man, Tomás, and his family, striving to emerge from the long shadow of the great famine. A New Perspective O'Farrell's book offers a new perspective on the history of Ireland and the impact of the great famine on families. Her research and writing have shed light on a little-known aspect of her family's history and the history of Ireland.
#Maggie O'Farrell #The Guardian #Fiction
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World Wide May 31, 2026

Trump Delays Iran Deal as Israel Deepens Lebanon Invasion on War Day 93

President Donald Trump said he is in no hurry to close a nuclear deal with Iran while Israel captur…
Donald Trump told Fox News he is in no hurry to finalize a nuclear deal with Iran as Israeli forces deepened their ground incursion in southern Lebanon, marking day 93 of the regional war. The statements came alongside reports of a captured strategic castle, new Iranian naval capabilities, and a draft memorandum that would release $12 billion in frozen Iranian assets.Intensifying Ground Operations: Israel Captures Beaufort CastleIsraeli troops seized the historic Beaufort Castle (Qalaat al‑Shaqif) near Nabatieh, the deepest Israeli advance in 26 years.The Israeli military warned residents south of the Zahrani River to evacuate and launched large‑scale operations across the Beaufort Ridge and Wadi al‑Salouqi.Air raids hit Arnoun, Kfar Tebnit, Kfar Remman, Kfarjouz and Dbeibine, while a 21‑year‑old Israeli soldier was killed and four wounded.Lebanon’s Prime Minister Nawaf Salam condemned what he called a “scorched‑earth policy” as forces push toward Nabatieh.Financial Stakes: $12 Billion Frozen Iranian Assets in Draft DealIranian state media cited an “unofficial” memorandum that would free $12 billion of Iranian assets frozen by the United States.U.S. officials reported that President Trump requested several amendments to the preliminary agreement during a White House Situation Room meeting.Congress advanced a U.S.–Israeli military integration plan, potentially deepening joint weapons research and production.Regional Ramifications: Heightened Tensions Across the Middle EastIran’s IRGC claimed to have shot down a U.S. drone and unveiled a new naval attack craft capable of 100 knots, signaling a rapid military modernization.The United States disabled a Gambia‑flagged vessel attempting to reach an Iranian port, prompting Tehran to accuse Washington of “betraying diplomacy.”Rear Admiral Habibollah Sayyari warned that any further aggression would meet an even stronger response.Israel’s expanded forward‑defense line now crosses the Litani River, tightening the front against Hezbollah.What Lies Ahead: Prospects for U.S.–Iran Negotiations and Regional StabilityTrump’s “no rush” stance suggests the nuclear framework will be refined before any release of assets, potentially extending negotiations into late 2026.Continued Israeli advances risk drawing Hezbollah into a broader ground conflict, which could pressure the U.S. to reassess its diplomatic leverage.The new U.S.–Israeli integration plan may lock Washington into a tighter security partnership, influencing future policy toward Iran.Analysts warn that without a clear de‑escalation path, the war’s 93‑day trajectory could expand beyond Lebanon, affecting regional energy markets and global diplomatic efforts.
#Donald Trump #Iran #Israel
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Health May 31, 2026

Breakthrough Cancer Jab Shows Unprecedented Results in Eradicating Tumors

A revolutionary cancer treatment called amivantamab has shown unprecedented results in clinical tri…
The Lead: Unprecedented Cancer Treatment SuccessDoctors have hailed "unprecedented" trial results that show a triple-action cancer jab can eradicate entire tumours in patients. In an international trial spanning 11 countries, the injection was offered to patients whose cancer had spread or come back and whose disease had failed to respond to other treatments.The Breakthrough: Amivantamab's Triple-Action ApproachThe jab, called amivantamab, shrank the tumours of more than a third of patients, with dramatic changes seen within weeks. In 15 of them, doctors found the drug had melted away their tumours altogether.The smart jab targets cancer in three ways. It blocks both EGFR (epidermal growth factor receptor), a protein that helps tumours grow, and MET, a pathway that cancer cells often use to escape treatment. It also helps activate the immune system to attack the tumour.The Clinical Trial Data: Impressive Response RatesIn the trial, 102 patients with head and neck cancer, the world's sixth most common cancer, were given the jab. Tumours shrank or disappeared completely in 43 patients, including 28 whose tumours shrank significantly and 15 who saw them eradicated entirely.Patients receiving amivantamab lived for a median of 12.5 months overall after starting treatment, despite having a form of cancer with very poor outcomes, once standard treatments stop working.The Impact Analysis: New Hope for Treatment-Resistant CancersKevin Harrington, professor in biological cancer therapies at the Institute of Cancer Research, London (ICR), said: "These are unprecedentedly strong responses in patients whose disease has become resistant to both chemotherapy and immunotherapy. This is a group of patients for whom treatment options are extremely limited, so seeing this level of benefit is very striking."Researchers also highlighted that the trial focused on people with head and neck cancers that did not include those with human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. That is particularly significant, they said, since head and neck cancers not caused by HPV are usually harder to treat, making progress in this group hugely important.The Patient Experience: Transforming Quality of LifeOne of the first patients to benefit was Carl Walsh, 56, who was diagnosed with tongue cancer in May 2024 and joined the OrigAMI-4 trial at the Royal Marsden in July 2025. "I was initially treated with both chemotherapy and immunotherapy, which unfortunately were not successful," he said. "At that point, I was recommended for the OrigAMI-4 trial. I'm now on my 17th cycle of treatment and I'm very pleased with the progress so far."Unlike many cancer treatments, amivantamab is given as a tiny jab under the skin rather than via an intravenous drip, making treatment quicker and more convenient for patients and much easier to deliver in outpatient clinics.The Future Outlook: Expanding Treatment ApplicationsThe results will be presented on Sunday in Chicago at the world's largest cancer conference, the annual meeting of the American Society of Clinical Oncology (Asco).Amivantamab, developed by Johnson & Johnson, is now being evaluated in about 60 clinical trials, primarily for lung cancer, but also for colorectal, brain and gastric cancers.Prof Kristian Helin, the chief executive of the ICR, said: "This study demonstrates how the development of new treatments through rigorous cancer research may lead to meaningful advances, even for patients with very limited treatment options. Achieving this level of tumour response and encouraging survival outcomes in such a challenging-to-treat group represents a significant step forward."
#Cancer #Amivantamab #Johnson & Johnson
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Health May 31, 2026

AI and Robotics Aim to Humanise Australia’s Ageing Care Industry

Australia’s ageing population and aged‑care workforce shortages are prompting a surge in AI, roboti…
Australia faces a rapidly ageing population and chronic shortages of aged‑care staff, driving an emerging industry of AI‑enabled robots, virtual‑reality experiences and other digital tools aimed at improving resident wellbeing.AI and Robotics in Australian Aged Care: Current LandscapeProf Wendy Moyle, who runs the social‑robotics laboratory at Griffith University, argues that technology should support humans rather than replace them. She points to a Chinese virtual hospital as a sign of rapid progress, while warning that many inventions are built without input from health professionals or end‑users.Demographic Trends Driving Demand for Tech SolutionsAustralia’s population is ageing, increasing demand for residential and home‑based care.Workforce shortages in aged‑care facilities exacerbate challenges of neglect and abuse.Technology is not a magic bullet, but pilots show measurable benefits for mood, cognition and social isolation.How Tech Is Shaping Human Connection in Care HomesAt St Vincent’s Care in Toowoomba, residents board the “St Vincent’s Express” – a replica train station and carriage that combines physical sets with screens showing Alpine scenery. Manager Elzette Lategan says the experience “takes boredom, loneliness and isolation away and brings in hope.”The organisation Aged Care Research and Industry Innovation Australia notes that virtual reality can improve mood, memory, problem‑solving and spatial awareness, and may reduce pain and anxiety.Companion robots such as Abi, produced by Andromeda, use AI and machine‑learning to recognise faces, interpret emotions and remember conversations, speaking in 90 languages to cater to diverse residents.Future Outlook: Integrating AI While Preserving HumanityMoyle cautions that Australia must “think outside the square,” ensuring that tech augments the human touch rather than substituting it. Continued collaboration between engineers, clinicians and residents will be essential to scale innovations that genuinely enhance quality of life for older Australians.
#Wendy Moyle #Griffith University #Andromeda
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Health May 31, 2026

Nigeria's 'Algorithmic Apothecary' Fuels Surge in Risky Herbal Cures

Nigeria's growing online trade in unverified herbal remedies, promoted through social media algorit…
The Rise of Nigeria's Digital Herbal Marketplace In Abuja, Nigeria, Oke Bola thought a fertility supplement she found online might help her conceive. Instead, within days of taking it, she struggled to breathe. Her experience reflects a growing online trade in unverified herbal remedies promoted across social media platforms. Bola, who is in her early 40s and has never had children, bought the supplement earlier this year and increased the recommended dosage, hoping for quicker results after hearing about it from friends and family. "I recognised the symptoms of asthma; the wheezing sound at night was familiar," she told Al Jazeera. "When I checked online, I realised it could be from the herbal medication." Her experience is not isolated. Across Nigeria, doctors and pharmacists report a surge in social media-driven self-medication, particularly involving unverified herbal products. This trend is worsening health outcomes, delaying treatment, and adding pressure to an already strained healthcare system serving about 230 million people. Nigeria's young, hyperconnected population increasingly uses digital platforms for health information and advice. But that access has also created what Dr Isaac Kolawole and Dr Fidelis describe as an "algorithmic apothecary" – an unregulated online marketplace where influencers and anonymous sellers promote remedies directly to consumers with little or no scientific backing. Health Impacts of Unverified Herbal Remedies Within this ecosystem, herbal remedies, long part of Nigeria's medical and cultural landscape, are increasingly repackaged as miracle cures, sometimes with dangerous consequences. Doctors report more patients arriving at hospitals only when their conditions have significantly worsened, often after prolonged use of unverified treatments. A consultant nephrologist at the University College Hospital in Ibadan, Dr Yemi Raji, said herbal medicine continues to play a role in kidney disease cases in Nigeria. "When you take herbal medication, you are taking both the good and the bad," he said. "Patients often arrive late, when treatment is more difficult and expensive." Dialysis alone can cost between 50,000 and 100,000 naira ($36-72) per session, several times a week. Studies link herbal use to kidney and liver disease cases across Africa, including findings that about 46 percent of liver disease admissions in one Nigerian hospital involved herbs or roots. A 2022 study found that 76.65 percent of participants had used herbal medicine, with more than a third combining herbal and conventional treatments while 82.44 percent did not inform their doctors. The Algorithmic Amplification Effect On a smartphone screen, relief is just a click away: fertility tonics, eye drops promising restored vision, syrups claiming to "flush out" disease. The advertisements are polished, persuasive and constant, woven into TikTok, Facebook, Instagram and X feeds. "The platforms themselves amplify this effect," said Dr Egemba Chinonso Fidelis, a public health advocate known online as Aproko Doctor. "Their algorithms reward engaging content and push it to wider audiences." Even users who try to avoid such content often encounter it repeatedly, shaped by emotional storytelling, music and urgency-driven messaging. A 2025 Nigeria-based study on Jinja Herbal Mixture found it appeared safe for short-term use within tested dosage ranges, but researchers recorded biochemical changes at higher doses, including altered creatinine and sodium levels in test subjects, signs of possible kidney and liver stress. The study called for further research into long-term effects and interactions with conventional medicines. Regulatory Challenges in the Digital Age The National Agency for Food and Drug Administration and Control (NAFDAC) says it is working to track unregistered manufacturers, but enforcement remains difficult, especially online. "With the sheer volume of products online, enforcement has limited reach," said Isaac Kolawole, the southwest zonal director of NAFDAC. Many sellers use fake or incomplete addresses, making them difficult to trace. NAFDAC requires strict registration, testing and approval before herbal products can be sold or advertised, but regulation has not kept pace with online commerce. Fidelis argued that stronger regulation alone is not enough. "If there are no consequences for lying about healthcare online, people will keep doing it," he said. He noted that scammers have even used AI-generated versions of his image to promote fake products. "Real medicine does not promise to cure everything, and it does not rely on countdowns," he added. "Scammers do." Path Forward for Safer Digital Health As Nigeria's digital economy expands, the intersection of technology and healthcare will only grow more complex. Fidelis stressed that access to affordable healthcare must improve, public trust must be rebuilt, and digital platforms must take responsibility for the health content they amplify. Pharmacist Akinade Akinlolu noted that while conditions like diabetes and hypertension can be managed, online claims often suggest cures. "Economic pressure is also pushing people towards cheaper or 'miracle' alternatives," he added. "Without stronger safeguards," Fidelis warned, "the algorithmic apothecary will continue to grow and put more people at risk." The challenge for Nigeria's healthcare system is to harness the power of digital platforms while ensuring they promote evidence-based care rather than potentially harmful alternatives.
#Nigeria #Herbal medicine #Social media
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