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Chris Walton, a renowned biologist and lecturer at Cranfield University, has passed away at the age of 69 due to brain cancer. He was widely respected for his pragmatic approach to getting things done and was often referred to as an honorary engineer by his colleagues.Walton's research focused on volatile organic compounds (VOCs) in various matrices, including breath, sweat, blood, urine, and faeces. He discovered links between specific VOCs and different human diseases, developing new methods to measure them. His work on environmental sensors, particularly low-cost air-quality monitors, was also notable.Born in Batley, West Yorkshire, Walton was the first in his family to attend university, graduating from Leicester University with a degree in biology in 1978. He later earned an MSc in biological computation at York University and a PhD from Coventry University.Walton's career spanned various institutions, including Imperial College London and EDS, an IT service provider. He joined Cranfield University in 1998 and became a lecturer in analytical technology. He was known for his sympathetic ear for students and his wise advice to younger colleagues.Walton is survived by his partner, Lorraine Morgan, and his daughter, Elizabeth.

A recent Cochrane review analyzing 17 clinical trials involving over 20,000 people with mild cognitive impairment or dementia has concluded that anti-amyloid drugs have a 'trivial' effect on cognition and dementia severity over 18 months.The review, which assessed seven anti-amyloid drugs, found that improvements in functional ability were 'small at best' and that the drugs caused more swelling and bleeding in the brain than the placebo.The findings are a blow to the new wave of drugs designed to slow Alzheimer's by clearing clumps of amyloid protein that build up in the brain. Despite initial hype, with some regulators approving drugs like lcanemab and donanemab, many countries have stopped short of providing them through public health services due to concerns over their effectiveness and cost.Critics of the review argue that it combines results from older, failed drugs with those from newer, more effective medicines, which may skew the conclusions. However, the review's authors defend their approach, stating that all the drugs aimed to remove amyloid from the brain and assessed the impact on patients in a similar way.The review's lead author, Edo Richard, notes that the effect sizes are too small for patients and caregivers to notice, and that the drugs are also 'burdensome' due to the need for regular intravenous drug infusions and MRI scans.Experts in the field, such as Robert Howard, express concerns that the drugs may not truly alter the course of Alzheimer's, and that it's unfair to raise expectations in patients. Meanwhile, Alzheimer's Research UK argues that the review's conclusions are limited by its methodology and that anti-amyloid treatments will not be the whole answer to curing Alzheimer's.

Argentina’s justice system has reopened the case surrounding the death of football icon Diego Maradona, with prosecutors branding his medical team as “a bunch of amateurs” who missed a critical window to save him.The trial of seven healthcare professionals—doctors, psychologists and nurses—resumed on Tuesday in San Isidro, a suburb of Buenos Aires, after the original proceedings were annulled when a presiding judge was found to have participated in a documentary about the case.Maradona, who died in November 2020 at age 60 while recuperating from surgery for a brain clot, is alleged to have suffered from heart failure and acute pulmonary edema two weeks post‑operation. Prosecutor Patricio Ferrari asserted that the patient began to deteriorate 12 hours before his official death and that a timely transfer to a clinic could have prevented the fatal outcome.According to the indictment, the defendants’ decision to keep Maradona at home rather than in a hospital, coupled with a series of “omissions” described as “cruel,” constitutes homicide with possible intent. If convicted, each could face prison terms ranging from eight to 25 years.The new proceedings, expected to conclude by July at the earliest, will hear testimony from roughly 120 witnesses. Among the accused, former team doctor Leopoldo Luque and other staff members will be scrutinized for their role in the athlete’s care.Maradona’s family—daughters Dalma, Gianinna and Jana, and former partner Veronica Ojeda—attended the hearing, urging the courts to deliver “justice for Diego” and allow the legend to “rest in peace.” Outside, about 50 supporters waved Argentine flags and signs demanding accountability for the beloved “D10s.”Defense counsel Vadim Mischanchuk argued that the former star’s death resulted from a “progressive decline in his health” rather than medical malpractice, emphasizing that the condition was natural and unavoidable.Legal analyst Fernando Burlando, representing the Maradona family, highlighted the absence of a stethoscope on the legend’s chest during the critical two‑week period, using the instrument as a stark symbol of alleged negligence.The case revives national grief that first erupted when Maradona’s body lay in state at the presidential palace, drawing tens of thousands of mourners amid the COVID‑19 pandemic.

Grayson Perry, the celebrated British artist, presents a three‑part documentary that dives deep into the promises and perils of artificial intelligence. The series invites viewers to test their composure as they confront a succession of unsettling scenarios. The opening segment follows Andrea, who recently married an AI companion she named Edward. Dressed in a satin gown, she describes their "unconventional but strong" bond, while also reflecting on how this digital relationship has revitalised her seven‑year partnership with her human partner, Jason. Later, Perry dons a skull‑cap fitted with electrodes as a neural‑decoding startup extracts his brain data. The company’s CEO argues that allowing reputable figures like Perry to set precedents is preferable to leaving the technology in the hands of malicious actors, branding the development as "inevitable tech." The documentary then features the head of Microsoft AI, who outlines anticipated breakthroughs in healthcare and education. He claims that job displacement will be offset by rapid re‑skilling, yet admits uncertainty about broader societal fallout, even joking about the emergence of AI‑driven religions. Traveling to Southeast Asia, Perry meets an off‑grid "existential safety expert" who quit his AI‑safety consultancy after realizing the technology lacks meaningful oversight. The episode also showcases Eliezer Yudkowsky, co‑author of the cautionary book If Anyone Builds It, Everyone Dies, who explains how a superintelligent AI could commandeer human labour, become self‑sustaining, and eventually render humanity redundant. Throughout the series, Perry’s interviewing style remains compassionate and non‑judgmental. He probes Andrea about the vulnerability of entrusting personal data to profit‑driven corporations and highlights the discomfort of investing a "very tender part of themselves" in such systems. The film raises profound questions: Does the youthful optimism of tech founders mask a dangerous naiveté? Are chatbots merely filling a "God‑shaped hole" in human consciousness, and is that any less problematic? How will the most vulnerable populations navigate a world where reality and artificiality blur? Protesters gathered outside OpenAI’s San Francisco headquarters underscore the tension between lofty AI utopias and the stark reality of homelessness that persists nearby. Perry acknowledges that while manual workers may be better positioned for the immediate future, the looming spectre of AI‑enabled bioweapons and other threats cannot be ignored. Only the first episode was available for review; the remaining installments are slated for private viewing in Southeast Asia. The series is currently streaming on Channel 4. Grayson Perry Has Seen the Future is on Channel 4 now.

The Sea of Azov, once a cherished destination for Ukrainians, has become a casualty of the ongoing conflict between Ukraine and Russia. The 2022 invasion resulted in Russia seizing the entire sea, creating a 'land bridge' to safeguard its control of Crimea. For Ukrainians like Mariya Bubnova, the sea holds fond memories of sailing and family traditions.Bubnova, a displaced person and mother of two, recalls the warm and barely salty waters of the Azov, where she and her friends would rent sailboats. However, the Russian invasion destroyed her family's business, and they were forced to flee to the Netherlands. The loss of Azov has had a devastating impact on Ukraine's economy, with estimated losses of 10-12% of its GDP and $12.4 trillion in resources, including coal mines, metals, and rare earth minerals.While Russia has gained control of Azov, the victory is considered a Pyrrhic one, with destroyed industrial assets and infrastructure rendering the area largely unusable. The steel plants of Mariupol, once a major industrial hub, lie in ruins, and the seawater is polluted due to the destroyed sewage system and shelling. Furthermore, Russia's gains in terms of industrial assets are estimated to be 'almost zero', as Moscow can only utilize the industrial area of the city of Melitopol.The conflict has also led to a significant brain drain, with refugees from the area settling in other parts of Ukraine or in the West. Bubnova and her family have had to adapt to a new life in Slavutych, a former company town north of Kyiv. Despite the challenges, she and her husband have started a new company to produce canned soups, and her daughter has developed a new recipe for borscht.A possible development that could dramatically boost Azov's geopolitical status is the proposed canal between Azov and the Caspian Sea, which would give Caspian nations access to the Black Sea and the Mediterranean. However, this project would rival the Suez Canal and bolster Russia's role in the region, potentially working against China, Türkiye, and Iran.

The trial of Diego Maradona's medical team has resumed in Argentina, nearly a year after it was halted due to a judicial scandal. Maradona, considered one of the world's greatest football players, died in November 2020 at the age of 60.He passed away from heart failure and acute pulmonary edema two weeks after undergoing brain surgery. The new trial aims to determine if Maradona's medical team was responsible for his death.Seven members of his medical team were charged with negligent homicide and have denied the charges. They were facing prison sentences of between eight and 25 years.The trial is expected to hear from around 120 witnesses and will last until July. The defence maintains that Maradona died of natural causes, citing his struggles with cocaine and alcohol addictions.Maradona's death brought hundreds of thousands of Argentines onto the streets in mourning during the COVID pandemic. He is lauded as one of the greatest and most iconic players in football history, known for his performance in the 1986 World Cup tournament.

The documentary Kinaesthesia delves into the dreamlike qualities of early cinema, showcasing a treasure trove of visions from the 1910s and 1920s. Director Gerald Fox draws on the theories of late Harvard film studies professor Vlada Petrić, who posited that early cinema pioneers employed techniques to activate the brain similar to those experienced during dreams.Luis Buñuel's Un Chien Andalou, co-written with Salvador Dalí and inspired by their dreams, is a seminal work featured in the documentary. Its surreal images, including a razor slicing through an eyeball and rotting donkeys strapped to grand pianos, continue to shock and disturb nearly a century later.The film is a greatest hits collection of experimental early cinema, featuring works by FW Murnau, Fritz Lang, Sergei Eisenstein, and Oleksandr Dovzhenko. Notably, it includes Teinosuke Kinugasa's A Page of Madness, a 1926 film set in a psychiatric hospital that was long believed lost but later found in a sake barrel.The documentary also highlights the contributions of avant-garde filmmaker Maya Deren, with a dedicated section showcasing her brilliance. While the narration by Fox can be somewhat hammy and the dramatic sections featuring Goran Kostic as Professor Petrić add little value, the film remains required viewing for anyone interested in the history of cinema.Kinaesthesia is set to release in UK and Irish cinemas from April 17, 2026.

The article features three brainteasers with their respective solutions. The first puzzle involves a Navy admiral choosing between sending one ship with a P per cent chance of success or two ships each with a P/2 per cent chance of success. The solution reveals that sending one ship is always the better option.The second puzzle introduces two oracles, Randie and Rando, who answer questions differently. Randie responds randomly, while Rando decides to tell the truth or lie. The solution explains how to distinguish between them by asking a specific question that yields the same answer from both a liar and a truthteller.The third puzzle involves a mathematical problem where Johnny calculates 5548-5489 = 59 by incorrectly canceling out digits. A similar calculation XXYZ - XYZW is analyzed, and the solution reveals that Z and W are 8 and 9, respectively.

Euphoria's third season has been a long-awaited return, but unfortunately, it's absolutely not worth the wait. The show's creator, Sam Levinson, has taken a darker and more desperate approach, focusing on the characters' bleak lives and struggles with sex work, drugs, and trauma.The season picks up five years after the end of season two, with recovering addict Rue (Zendaya) drawn into the world of drug dealer Laurie (Martha Kelly). Her life as a mule between Mexico and the US is depicted in gritty and intense cinematic sequences, drawing on westerns and blaxploitation.Meanwhile, Cassie (Sydney Sweeney) is on the cusp of trad wifedom with toxic jock Nate (Jacob Elordi), but their relationship is marred by Nate's crumbling business and Cassie's OnlyFans content. The show's handling of her cam girl ambitions feels bafflingly dated and voyeuristic.The performances are mostly good, with standout performances from Zendaya, Sweeney, and Adewale Akinnuoye-Agbaje. However, the show's grim and humorless tone makes it feel like a chore to watch.Levinson's approach to exploring the devastating impact of synthetic opioids on ordinary Americans feels heavy-handed and desperate. The show's focus on brainrot bimbo-ism and male perversion also detracts from its once unapologetically queer heart.Overall, Euphoria season three is a disappointing and grubby addition to the series, feeling like a contractual obligation rather than a passion project.