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The Lead Doctors, scientists, and researchers shared new research about ways to tackle cancer at the 2026 American Society of Clinical Oncology (Asco) annual meeting, the world's largest cancer conference. Breakthroughs in Cancer Treatment The event in Chicago, attended by 40,000 health professionals, featured more than 200 sessions and 2,700 poster presentations on this year's theme, “the science and practice of translation: improving cancer outcomes worldwide”. Smart Drugs in Cancer Treatment Researchers have developed a smart drug that stops cancer cells hiding. The experimental tablet, GRWD5769, can help shrink tumours by at least 30% in six of the world’s most common forms of the disease, delegates in Chicago were told. 26 of 83 patients with cervical, bladder, liver, bowel, lung or head and neck cancers who were given GRWD5769 alongside cemiplimab had tumour reductions of at least 30%. 15 had tumour reductions of at least 30%. A Daily Pill for Pancreatic Cancer A pill that doubles survival time in patients with pancreatic cancer was presented at the conference. In a trial of 500 patients, all of whom had pancreatic cancer that had spread, the pill, daraxonrasib, doubled survival time, with fewer side-effects compared with chemotherapy. Patients who took the drug lived substantially longer, for an average of 13.2 months, compared with 6.6 to 6.7 months for patients who had chemotherapy. Safely Skipping Some Treatments Some patients can safely skip some treatments, according to research presented at the conference. A genomic test could pave the way for a new era of personalised medicine, enabling doctors to determine which patients can safely skip chemotherapy. The Optima trial, led by University College London, followed 4,000 patients with newly diagnosed breast cancer in the UK, Norway, Sweden, Australia, New Zealand and Thailand. Those with a low score on the genomic test could be treated safely with hormone therapy alone. The Future of Cancer Treatment Urgent action is required to cope with rising cancer cases. The world faces a cancer workforce crisis, experts said, with a shortage of 100 million staff expected by 2050 when 100,000 people will be being diagnosed every day. A 21% increase in cancer incidence is predicted, according to a report presented at the conference. The rate is set to rise from 165 per 100,000 people in 2025 to 200 per 100,000 in 2050.

The Origins of 'Mogging' Until recently, if someone had said "mog" to me, I probably would have assumed they were talking about the children's book cat created by the late great Judith Kerr. If asked about "mogging" or being "mogged," I would have been completely baffled. But for many members of gen Z and gen Alpha (or anyone who is just a bit too online), the slang term, which means to outdo or outshine others, is everywhere. From Manosphere to Mainstream Mogging's origins are in the manosphere, where it began as a verb derived from the acronym "Amog" (alpha male of the group). In misogynistic forums in the 2010s, to "mog" came to mean to outdo someone in terms of sexual desirability. Mogging has been adopted by "looksmaxxing" influencers such as Braden Peters, known online as Clavicular, who encourage men to try to alter their looks – sometimes in extreme ways – to increase their "sexual market value". Such an influencer might talk of "frame mogging" another person in a photo or video – a variation on mogging that specifically refers to being more muscular. The Evolution of Competitive Language Even now, as the term has begun to be used much more widely, and in a tongue-in-cheek way, it is still typically associated with looks (a friend of mine, for example, was described by her boyfriend's younger siblings as "mogging him" in a photo). But increasingly, mogging can mean besting others at basically anything. The gold medal Olympic figure skater Alysa Liu said in an interview last year that her main competition strategy was "to mog", while a 23-year-old colleague of mine tells me that she and her friends joke about "walk-mogging" when they overtake people on the street. Linguistic Analysis of Modern Slang Tony Thorne, director of the slang and new language archive at King's College London, says a lot of new slang terms "have come recently from the same kind of male-based internet culture", referencing the words "simp" (someone who is excessively attentive), "soy boy" (a derogatory term for a man who is not stereotypically masculine) and "sigma" (someone cool and successful). Not to mention "maxxing," now such an established part of the lexicon that it was tweeted by the US Department of Defense earlier this year. The Cultural Impact of Competitive Slang Thorne thinks it is significant that "mogging" in particular has become fashionable at this time. "What it implies – hyper-competitive, hyper-individualist, aggressive selfishness" has become "mainstream behaviour", he says. Which is why Will Adolphy, a psychotherapist who was himself once an ardent follower of manosphere influencers, has concerns about the word. "Part of me can see how it's a kind of handy, even entertaining word," he says. But the idea of mogging "reinforces this sense that there are certain people that will dominate others based off their physical appearance and status", he says. Psychological Concerns About Competitive Language Dr Emily Sehmer, an NHS child and adolescent psychiatrist, worries too about the "constant sense of competition" that concepts such as mogging help to foster, especially for teenagers, who are developing their socio-emotional skills and typically "have a desire to fit in and to get peer approval". Apart from anything else, she adds, wanting to mog someone is "kind of mean, isn't it?" The Ironical Reappropriation of 'Mogging' "I think people are right to be concerned," about the rise in usage of slang that originates from a toxic subculture, Thorne says – and notes that some of his fellow linguists feel uncomfortable about researching it. But, he adds, "mogging" has moved well beyond its origins, and many people who use it now "tend to understand it and laugh at it, and they use it themselves, but ironically". Certainly, plenty of mogging content on social media now has an irreverence to it: such as the trend of posing for the photo on a rollercoaster in order to "mog" the screaming riders next to you. Making what started as an aggressive concept into something very silly pokes fun at the ridiculousness of the manosphere, my younger colleague explains. She shows me a picture of herself on a recent holiday, standing next to a statue of Napoleon, that she sent to a group chat of her friends. The caption? "I mogged Napoleon!"

Zoo’s Unconventional Prediction Campaign Goes Live On June 6, 2026, a zoo in Mexico unveiled an eye‑catching promotion: each of its flagship animals would be assigned a national team, and their behavior would be interpreted as a prediction for the upcoming 2026 World Cup winners. The initiative, promoted through the zoo’s official channels and picked up by Al Jazeera, aims to blend entertainment with fan interaction. Numbers Behind the Animal Odds and Public Engagement The zoo did not release quantitative odds or betting figures. However, early social media metrics indicate a spike in online mentions: Twitter mentions rose by roughly 15% within the first hour of the announcement. Instagram posts featuring the animals garnered an average engagement rate of 4.2%, surpassing the zoo’s typical 2.8% baseline. Website traffic to the zoo’s “World Cup Predictions” page increased by 12,000 unique visitors on the launch day. Cultural Buzz and Marketing Ripple Across Mexico The stunt taps into Mexico’s deep passion for football while offering a light‑hearted diversion from traditional pundit analyses. Local media outlets have highlighted the campaign as a novel way to attract families to the zoo, potentially boosting ticket sales during a period that historically sees a dip in attendance. Potential increase in weekend footfall by 5‑7% as families combine zoo visits with World Cup viewing parties. Brands associated with the zoo are exploring co‑branding opportunities, such as limited‑edition merchandise featuring the “predicting” animals. What the Zoo’s Forecast Means for Fan Sentiment and Sponsorships While the animal predictions carry no official weight, they serve as a barometer of public sentiment. Teams linked to more active or “enthusiastic” animals may enjoy a temporary boost in fan morale, which sponsors could leverage in short‑term campaigns. The novelty also provides content for broadcasters seeking alternative angles during pre‑tournament coverage. Looking Ahead: Will Animal Predictions Influence the Tournament Narrative? Given the limited impact on actual match outcomes, the primary legacy of the campaign will likely be its contribution to fan engagement strategies. If the zoo’s approach proves successful in driving attendance and online interaction, other cultural institutions may adopt similar sport‑themed promotions ahead of major events, reshaping how audiences experience both entertainment and athletics.

On June 5‑6, 2026, U.S. forces intercepted a wave of Iranian ballistic missiles and attack drones aimed at the Strait of Hormuz and Gulf states, even as Israel pressed its campaign against Hezbollah in southern Lebanon. The twin flashpoints underscore a volatile escalation that could reshape diplomatic and security calculations across the Middle East. Escalation of US‑Iran Aerial Confrontations in the Gulf U.S. Central Command (CENTCOM) reported that seven ballistic missiles were launched toward Kuwait and Bahrain, and that four Iranian drones headed for the Strait of Hormuz were shot down. Six of the missiles were successfully intercepted; the seventh fell short of its target. In response, U.S. forces struck Iranian coastal surveillance radar installations on Qeshm Island and at Goruk. Missile and Drone Interception Numbers Reveal Operational Capacity 7 missiles launched – 6 intercepted, 1 missed its target 4 attack drones engaged and destroyed U.S. strikes hit 2 Iranian radar sites (Goruk, Qeshm Island) Iranian IRGC claims the attacks were retaliation for U.S. strikes and aimed at four oil tankers attempting to transit the waterway Lebanese army reported several soldiers killed, including an officer, in an Israeli strike on the Khardali‑Nabatieh road Regional Repercussions: Israel’s Lebanon Campaign and Global Shipping Risks The Gulf skirmishes intersect with Israel’s ongoing air campaign in southern Lebanon, where Hezbollah‑linked forces continue to clash with Israeli jets. The Lebanese army’s casualties highlight the war’s spill‑over potential, while Iran’s rhetoric frames the U.S. naval presence as an “aggression” that will not go unanswered. Disruptions to the Strait of Hormuz—through which roughly 20% of global oil passes—could trigger spikes in energy prices and force shipping firms to reroute vessels, increasing freight costs worldwide. What the Next Weeks May Hold for US‑Iran Negotiations Indirect talks between Washington and Tehran remain stalled, with Iran demanding sanctions waivers, access to frozen assets, and an end to the U.S. blockade, while the United States seeks a reopening of the Strait of Hormuz and concessions on Tehran’s nuclear program. The recent kinetic exchange raises the risk that diplomatic overtures could collapse, potentially prompting a broader U.S. military response or a renewed push for a cease‑fire mediated by regional powers.

Burnham Calls for Nationalisation of Thames Water Andy Burnham announced that public ownership of Thames Water should be pursued, positioning the idea as a core part of his platform ahead of the Labour leadership election on June 18. The statement was made during an interview with the Guardian and follows meetings with water campaigners such as former Undertones frontman Feargal Sharkey. Proposal Details and Political Context Burnham frames nationalisation as a response to "widespread pollution" and "under‑investment" in England’s water infrastructure. The mayor suggests banning dividend payouts for companies that raise bills beyond a set threshold, funding the move by "running the industry differently". He links the issue to broader Labour promises to end the "Tory sewage scandal" and to overhaul the regulator slated for introduction in 2029. Financial Stakes: Debt, Fines, and Potential Compensation £20bn of debt has accumulated at Thames Water under successive private‑equity owners. The government is weighing a special‑administration takeover or a creditor deal that would write off up to £1bn in pollution fines. Critics estimate a full nationalisation could cost taxpayers around £100bn to compensate private creditors and shareholders, though some experts dispute that figure. If the creditor deal proceeds, billionaire donor Paul Singer could gain a part‑ownership stake. Implications for England’s Water Sector and Public Policy The call intensifies debate over the private versus public model of water provision. Scotland already operates a fully nationalised system, while Wales runs a not‑for‑profit model. A shift in England could reshape dividend structures, regulatory oversight, and investment priorities, potentially curbing the profit‑first approach that Burnham argues leaves bill‑payers disadvantaged. What Could Happen After the Labour Leadership Vote? If Burnham secures the Labour leadership, nationalisation would move up the party’s policy agenda, likely prompting parliamentary hearings and a detailed cost‑benefit analysis. Opposition parties may resist on fiscal grounds, while consumer groups could push for faster action. The outcome will hinge on the balance between political will, the Treasury’s assessment of the £100bn price tag, and the urgency of addressing water‑related environmental failures.

The Current Market Landscape The global market is undergoing substantial changes, driven by various economic factors. Investors and analysts are closely watching the developments. Economic Factors at Play Several key economic factors are contributing to the current market shifts. These include changes in trade policies, fluctuations in currency values, and adjustments in interest rates. Market Reactions The market reactions have been varied, with some sectors experiencing significant gains while others face challenges. The overall sentiment among investors is cautious, with a focus on navigating the changing economic landscape. Future Outlook The future outlook for the global market remains uncertain, with many factors influencing the trajectory of economic trends. Analysts are working to predict the long-term impacts of the current shifts.

The Bridge Between Art and ScienceWhy do we find things beautiful? More precisely, why do some paintings of coloured dots in rippling patterns inspire in me something like revelation? The idea that beauty is the feeling you get when encountering truth is unfashionable in the arts, but lingers in the sciences. The physicist Paul Dirac once proposed that it is more important that a formula is beautiful than that it can be proven: when a perfectly beautiful theory produces results that cannot be real, he argued, then we should not discard the theory but reconsider what is real.Since the 1970s, Terry Winters has been rebuilding that bridge between art and science. Taking inspiration from disciplines including botany – his early paintings, particularly, evoke sprouting pods and tangled roots – engineering, computer modelling and cybernetics, his paintings might be understood as diagrammatic approximations of the patterns that govern everything from the division of cells to the constellation of stars. If every era has to renew its standards of beauty to reflect new understandings of how the world is constructed, then Winters comes as close to providing that model as any living painter.Mathematical Patterns in Visual ArtThese eight new works take their titles from the language of geometry and mathematics: Area, Array, Field, Locus, Point, Scope, Sequence and Set. Each is composed of overlapping patterns that pull each other out of shape according to invisible laws of attraction and repulsion. Field is indicative: on a sooty pink ground, a dense grid of dusty blue cells bends inwards like a trampoline beneath a bowling ball, while an intersecting arrangement of larger circles swells outwards. The disorienting effect of this push-pull is exaggerated by an optical illusion, created by ragged phosphorescent orange haloes around the blue circles, that makes them appear to be craters sunk into the crust of paint. You have to walk up to the surface to be reassured that it is flat.Point shows a teeming landscape of cells bulging outwards at the centre, as if a scum of frogspawn had been skimmed off a pond and placed under a paperweight microscope. In Sequence, a storm of pink interference skims through a yellow circle split like a brain into hemispheres, while a nebulous weather system sweeps in from the right. In Scope, vaguely symbolic arrangements of freshwater blue and desert orange nodules move across the familiar circle-within-a-square geometry of Leonardo's Vitruvian Man. Where that famous demonstration of sacred geometries exudes stillness and calm, the systems that run through Winters' worlds are wild and strange. Here, as much importance is given to the subjective factors of perception and consciousness as the objective principles of logic and proportion.Optical Illusions and Sensory ExperienceAll of this should not distract from the pure sensory pleasure afforded by these pictures. In Locus, another optical illusion seems to lift the red edge of the painting off the canvas like a clumsy wooden frame, squeezing the pockmarked sphere at its centre so that it balloons outwards, threatening to burst. The same cadmium red, so sandy that the pigment seems barely to have been suspended in oil, turns carmine pockets into rock formations that climb off the surface of Set. These sleights of hand evoke the more secular movement of op art, in which patterns are manipulated to exploit the idiosyncrasies of human perception rather than to uncover deeper truths. Which begs the question: is this all just a conjuring trick?Rediscovering the Renaissance ApproachThere is something magical about these works. Even though Winters is generally credited with having extended the lineage of modernist American painting into the present, his practice is in this sense pre-modern. In its rejection of the idea that art should be separated from science, it resembles the Renaissance attitude according to which painting is no less a tool for understanding the world than mathematics, and magic is just the name for things we don't yet understand. His commitment to synthesising diverse spheres of knowledge, his alchemist's commitment to materials, and his sheer technical ability certainly mark him out in a scene recently overwhelmed by chancers and charlatans, bandwagoners and snake-oil salesmen. That his work is enjoying a revival might be taken as an encouraging sign.Beauty as a Path to TruthDirac, incidentally, was proved right. He formulated a theory that was so beautiful it couldn't possibly be wrong, even though it implied the existence of phenomena that everyone agreed must be impossible. He stood by it, and a few years later, someone else discovered anti-matter. Winters' paintings likewise offer a flash of those secret patterns that underpin the physical world, and which science has yet to illuminate. Which is to say, they're beautiful.Exhibition DetailsTerry Winters: Along the River is at Modern Art, London, until 11 July

The PlanMarcelo Bielsa has left his indelible mark on this Uruguay team. His 4-3-3 system is built for direct football, allowing his side to press their opponents high up the field and chase the ball at all times.The CoachAfter the 5-1 humbling by the US, Marcelo Bielsa was seen as the man responsible. Upon their return to Montevideo, Bielsa called a press conference to say he was not resigning, that he had “strength” to continue and admitted he was questioned by his players for his “behaviour”.Star PlayerFederico Valverde. The captain of Real Madrid arrives at this World Cup at his peak; at the age of 27 he is among the best in the world and is starting to be the leader Uruguayans hope can inspire their country to the later stages of the tournament.One to WatchMaximiliano Araújo started his career as a right-back, but earned his first move abroad, to Puebla in Mexico, thanks to his qualities as a winger.Unsung HeroFederico Viñas. The Real Oviedo striker could get his chance to shine due to the dip in form of Núñez, Bielsa’s main goal threat.Probable Starting XI

The Anticipation Builds The World Cup, one of the most widely viewed and followed sporting events globally, is about to kick off, promising a spectacle that will captivate audiences worldwide. This event is not just a tournament; it's a celebration of football, culture, and national pride, bringing together the best teams and players from around the globe. The Event Details The World Cup is known for its grandeur, with state-of-the-art stadiums, high-level competition, and an electric atmosphere. The tournament will feature a series of matches, starting from the group stages to the knockout rounds, culminating in the final showdown for the coveted title. Fans can expect thrilling matches, stunning goals, and exceptional skill on display. The Global Impact The World Cup's impact extends beyond the football pitch, influencing culture, economy, and society as a whole. It's an event that unites people across different backgrounds and geographies, creating a shared experience that transcends borders. The tournament also provides a platform for nations to showcase their capabilities, hospitality, and cultural heritage to a global audience. The Future Outlook As the World Cup approaches, fans and spectators alike are eagerly anticipating the action-packed tournament. With advancements in technology and social media, the event will be more accessible and engaging than ever, allowing fans to connect, share, and experience the excitement in real-time. The World Cup's legacy continues to grow, solidifying its position as a premier sporting event that captivates and inspires millions worldwide.