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President Donald Trump has taken a significant step to push for pharmaceutical deals by signing an executive order that could impose tariffs of up to 100% on some patented drugs. This move is part of his administration's effort to secure lower prices for medicines.Under the executive order, companies that have signed a 'most favoured nation' pricing deal and are actively building facilities in the US will have a zero-percent tariff. For those that don't have a pricing deal but are building such projects in the US, a 20 percent tariff will apply, but it will increase to 100 percent in four years.A senior administration official stated that companies still have months to negotiate before the 100 percent tariffs kick in. Bigger companies will have 120 days, and 180 days are offered for everyone else.The administration has already reached 17 pricing deals with major drugmakers, 13 of which have signed. The executive order aims to address the threatened impairment of national security posed by imports of pharmaceuticals and pharmaceutical ingredients.Critics, pharmaceutical leaders, and medical groups have warned of the consequences the new tariffs could bring, including increased costs and potential jeopardy to billions in US investments. The pharmaceutical company trade group PhRMA has expressed concerns that taxes on cutting-edge medicines will increase costs and could jeopardize investments.

The current global landscape is marked by uncertainty, with Donald Trump's policies contributing to a sense of instability. As the world grapples with the implications of the Iran war, including a potential global shortage of jet fuel, the UK is reevaluating its relationships. Keir Starmer, leader of the Labour Party, has argued that a closer partnership with Europe is in Britain's national interest. This stance is echoed by Rachel Reeves, highlighting the need for the UK to strengthen its ties with the EU to mitigate the risks of a global economic crisis. The article notes that 63% of Britons would vote to rejoin the EU if a referendum were held today, according to recent YouGov polling. This sentiment is reflected in the growing popularity of a youth mobility scheme that would allow young people to work and study abroad, a proposal that has gained traction even among Leave voters. Starmer's ally, Nick Thomas-Symonds, has been negotiating a deal that would align with EU rules on food and drink, potentially leading to the relabelling of certain products like marmalade. While challenges remain, including competitive trade interests, the article suggests that Europe is choosing unity in the face of crisis. The author, Gaby Hinsliff, argues that Britain has learned from its past mistakes and is now seeking to build a new relationship with the EU at speed. While rejoining the EU is not imminent, the will and political courage are needed to seize this second chance.

On a cobbled lane in Belfast’s Cathedral Quarter, the Kindred of Ireland boutique draws shoppers with oversized butter‑yellow linen blouses and Donegal mulberry tweed jackets accented by rose‑pink linen bows, signalling a fresh commercial pulse for a fabric that once defined the city.Linen earned Belfast the nickname “Linenopolis” when, at its height, the industry employed about 40% of Northern Ireland’s workforce. After a post‑war collapse, the trade faded, but today it is re‑emerging as a marker of local identity and sustainable fashion.Designer Amy Anderson, whose grandmother worked as a mill‑hand in Moygashel, says the fibre remains deeply personal for many families. Her modern, Japanese‑inspired silhouettes rely on linen’s natural structure to balance avant‑garde volume with comfort.Reviving a near‑extinct industry is daunting, yet Belfast’s history of turning adversity into opportunity—exemplified by the Titanic Quarter’s tourism boom—has attracted an eclectic coalition of supporters. Among them are former blacksmith Charlie Mallon, who has converted his 150‑year‑old Magherafelt farm into a regenerative flax operation, and fashion heavyweight Sarah Burton, former creative director of Alexander McQueen.Mallon’s restoration of heritage machinery aims to keep flax “field‑to‑fibre” in Ireland, preserving the long fibre length that makes linen less prone to creasing. He contrasts this with most modern linen, which is “cottonised” in China, shortening fibres and increasing wrinkles.Burton’s two‑day field trip to Northern Ireland inspired the spring 2020 Alexander McQueen collection, featuring a beetled linen gown with a pearl‑like sheen that debuted on the Paris runway.In autumn, the Prince and Princess of Wales visited Mallon Farm, expressing a rare interest in sustainable fashion and regenerative agriculture. The Princess, who usually avoids media focus on her wardrobe, asked detailed questions about the Andersons’ brand, underscoring the royal endorsement of Belfast’s textile renaissance.The city’s fashion resurgence is also celebrated at the Ulster Museum’s “Ashes to Fashion” exhibition, which juxtaposes historic silk ballgowns with contemporary pieces by Irish designers, including Kindred of Ireland.Looking ahead, Kindred of Ireland plans a temporary boutique in central London, building on a successful six‑week Mayfair pop‑up that the brand describes as “commercial rocket fuel.” The Andersons note that Northern Irish firms benefit from full access to the UK market while still aligning with certain EU single‑market rules under the Windsor framework, offering a strategic advantage for product‑focused businesses.

The conflict between Iran, the US, and Israel has taken a devastating toll on civilians, with widespread destruction and displacement reported across the country.At the Kapıköy border crossing in eastern Turkey, a mountain pass that serves as one of the few gateways to the west from Iran, many Iranians are fleeing the country due to the intensifying conflict.Amir, a 33-year-old foreign exchange and cryptocurrency trader from Tehran, is one of them. He described the nightly bombardments and said, 'Every night they are bombarding. Boom. Because of the war.'Others, like a pharmacologist from Tehran, are traveling to see their families in Europe, citing anxiety and frustration with the current situation. 'All of the people live with anxiety,' she said. 'We are very tired of the revolution of [the] Islamic republic of Iran.'The UN refugee agency reports that close to 64,000 Iranians arrived in Turkey between March 3 and 30, while more than 48,000 Iranian nationals returned to Iran.The International Organization for Migration estimates that more than 82,000 residential units have been hit by the US and Israeli strikes, affecting 180,000 people.Many at the Kapıköy border point expressed fear and uncertainty about the future, with some saying they were waiting to see what the outcome would be before making a decision.The conflict has had a significant impact on the economy, with part-government-owned corporations ordering people back to work and many businesses forced to close.As the situation continues to deteriorate, many are seeking safety abroad, while others are returning to Iran to be with their families.

US senators have strongly rebuked Ticketmaster for increasing ticket fees following a regulatory crackdown on hidden charges. This move has been described as a 'bait and switch' tactic, leaving consumers with higher costs.The Federal Trade Commission (FTC) had mandated Ticketmaster to disclose all concert ticket fees upfront, known as all-in pricing, starting last May. In response, the company removed the order processing fee charged at the end of a transaction. However, documents obtained by the Guardian reveal that Ticketmaster simply raised other fees to offset the loss, potentially violating the FTC's ban on misleading fees.Senator Richard Blumenthal from Connecticut expressed his concerns, stating, 'Ticketmaster seems to believe it has a get-out-of-jail-free card to ignore antitrust and consumer protection laws. The FTC is going to have to choose whether to protect consumers and enforce the law, or cave to Ticketmaster lobbyists.'The FTC had sued Ticketmaster and its parent company, Live Nation Entertainment, last September for hiding mandatory fees until the end of the transaction. Ticketmaster claims it complies with the FTC's all-in pricing rules.In response to the criticism, Ticketmaster stated, 'Since May 2025, tickets on Ticketmaster.com have displayed the full price upfront in line with the FTC's all-in pricing rule. We also provide explanations of fees during the purchase process and maintain a dedicated page with additional information.'Senator Elizabeth Warren from Massachusetts also criticized Ticketmaster, saying, 'Too many giant monopolies think the law doesn’t apply to them, and it’s American families who are forced to pay the price.'An ongoing federal trial is examining whether Ticketmaster operates an illegal monopoly in the live music industry. The company denies these allegations.

Several ships have successfully navigated the Strait of Hormuz, a vital waterway that has been effectively closed since the start of the war in Iran. The development comes as shipping companies and international leaders work to ensure the passage of critical cargo, including oil and gas supplies that account for about a fifth of the world’s total. A French container ship owned by CMA CGM, the CMA CGM Kribi, which sails under the flag of Malta, is reported to have passed through the strait with cargo. This marks a significant development as it is believed to be the first ship owned by a western shipping line to make the journey. The blockade has led to increased oil and gas prices globally and growing concerns about food security, as a third of the global trade in raw materials for fertiliser normally passes through the strait. International leaders are expected to meet next week to discuss possible solutions, including clearing sea mines and rescuing trapped ships. The UK’s Foreign Secretary, Yvette Cooper, has stated that coordinated action is needed to pressure Iran into reopening the strait. The US President, Donald Trump, has claimed that the US could “easily” open up the strait but that it would require “a little more time”.

The blockade of the Strait of Hormuz has raised concerns about a potential global food crisis due to its impact on fertiliser supplies. The strait is a critical passage for 20% of global natural gas shipments and a third of the global trade in raw materials for fertiliser.The head of the International Rescue Committee, David Miliband, has warned that the situation is a 'food security timebomb', with the window to avert a massive global hunger crisis rapidly closing.Fertiliser prices have already risen by more than 60% in Egypt, reaching $780 (£586) a tonne, up from about $484 in late February. The Qatar Fertiliser Company (QAFCO), the world's largest single site for urea exports, has been offline for almost a month.The Middle East is the source of about 45% of the global trade in sulphur, a key raw material for fertiliser manufacture. Iran is the fourth-largest global exporter of urea, the most widely used nitrogen fertiliser.A prolonged transport shutdown could disrupt production and increase costs, leading to higher food prices and exacerbating global hunger. The world's poorest countries are among the most vulnerable to fertiliser price rises.

Recent maritime traffic reports confirm that vessels heading to Pakistan have passed through the Strait of Hormuz, one of the world’s most crucial chokepoints for oil and cargo shipments.The transit underscores the strait’s importance for Pakistan’s trade routes, linking the nation’s ports with markets in the Gulf, Europe and beyond. Maintaining open and secure passage through this narrow passage remains essential for the stability of regional and global supply chains.

Pakistan and Afghanistan have confirmed they are holding talks in China aimed at ending the worst conflict between the South Asian neighbours since the Afghan Taliban returned to power in 2021.Senior officials from both countries are holding preliminary talks in the northwestern Chinese city of Urumqi to try to secure a ceasefire to end months of cross-border attacks, Pakistan’s Foreign Ministry spokesperson Tahir Andrabi said on Thursday.The fighting has killed dozens of people on both sides and disrupted trade and cross-border travel since it started in October.Pakistan accuses Afghanistan of harbouring fighters who carry out attacks inside Pakistan, especially the Pakistani Taliban, known as Tehreek-e-Taliban Pakistan (TTP). The group is separate from but allied with the Afghan Taliban, which took over Afghanistan in 2021 following the chaotic withdrawal of United States-led troops.Andrabi told reporters in Beijing that the government hoped for a “durable solution”.“Our participation [in talks] is a reiteration of our core concerns,” he said.“The burden of real process, however, lies with Afghanistan, which must demonstrate visible and verifiable actions against terrorist groups using [its] soil against Pakistan.”Following China’s request for talks, Afghanistan’s Taliban government said it had sent a “mid-level delegation” to Urumqi.The Afghan side “intends to hold comprehensive and responsible talks with the other side on good neighbourliness, strengthening trade relations, and effective management of security issues”, Foreign Ministry spokesman Abdul Qahar Balkhi said.Pakistan described the negotiations as “working-level talks”.“Our delegation has not returned yet,” Islamabad’s Foreign Ministry spokesman said.China, which also borders both countries, has been trying to mediate a negotiated settlement to the conflict.Beijing deployed a special envoy to try to broker a deal last month, but the diplomatic effort was followed by Pakistani strikes on a Kabul rehab centre that prompted international condemnation.More than 400 people were killed in the attack, according to Afghan officials. Islamabad said the strike targeted military installations and “terrorist support infrastructure”.The two sides then announced a pause in fighting to mark the end of the Muslim holy month of Ramadan, at the request of Saudi Arabia, Qatar and Turkiye.But sporadic attacks have been reported in border areas since the temporary truce ended.