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Tehran – Iranian officials warned that the United States must increase pressure for any peace agreement while urging their supporters to keep the streets under control.Parliament speaker Mohammad Bagher Ghalibaf said the US delegation in Islamabad “failed to gain the trust of the Iranian delegation” during the marathon talks.US President Donald Trump announced an immediate naval blockade of the Strait of Hormuz and declared that US forces are “locked and loaded” to finish Iran at the “appropriate moment.”Iran hailed the delegation’s refusal to accept Washington’s core demands – ending nuclear enrichment and relinquishing control of the Strait – as a sign of defiant resolve.Judiciary chief Gholam‑Hossein Mohseni‑Ejei thanked the Islamabad team for “guarding the rights” of government supporters, including paramilitary forces that have been gathering in Tehran’s main squares for more than six weeks.State television aired an IRGC aerospace officer urging flag‑waving crowds not to worry, stating, “If the enemy does not understand, we will make them understand,” which was met with cheers demanding more missile and drone attacks.Iranian officials blamed Trump’s “excessive demands” for the talks’ failure, noting the Ministry of Foreign Affairs did not expect an agreement after a single day of negotiations.Hard‑line parliamentarians expressed satisfaction with the stalemate, viewing Iran as holding the upper hand. Deputy speaker Hamidreza Haji‑Babaei said only a UN Security Council resolution signalling US surrender would lift sanctions on Iran.Lawmaker Amir Hossein Sabeti of the Paydari faction thanked the negotiating team for standing by red lines and called for “resistance in the field against these evildoers.”The sudden announcement of a two‑week cease‑fire left pro‑state voices disappointed; local media reported the Iranian delegation numbered over 85 members, including state‑affiliated journalists and factional analysts.The talks confirmed that a diplomatic breakthrough was not imminent and hinted at further escalation, though not necessarily a return to full‑scale fighting.National security commission head Ebrahim Azizi dismissed Trump’s blockade threats as “excessive talk.”The IRGC warned it would meet any vessel passing the Strait of Hormuz with “full force” and rejected US claims that two warships had already transited the waterway.Russian President Vladimir Putin told Iranian President Masoud Pezeshkian he remains ready to facilitate a Middle‑East peace settlement.Pezeshkian, focused on domestic affairs, reaffirmed support for Supreme Leader Ayatollah Ali Khamenei and announced that schools and universities will continue online via a limited intranet.Iran’s economy continues to suffer from chronic inflation, rising unemployment and a near‑total internet shutdown, deepening public hardship.

Peruvians are heading to the polls to elect their ninth president in less than a decade, a period marked by political instability and corruption scandals that have led to widespread voter disillusionment.Since 2018, Peru has seen eight presidents, with a high turnover rate marred by impeachments and corruption scandals. This has resulted in weak governments and a lack of trust in the political system.On Sunday, 27 million Peruvians are eligible to vote, with polling stations across the country opening at 7am (12:00 GMT) and closing at 5pm (22:00 GMT). Preliminary results are expected shortly afterwards.The presidential ballot features 35 candidates, including a comedian, a media baron, a political dynasty heiress, and a hard-line ex-mayor. However, all major candidates continue to poll well below the 50 percent needed to win the election, making a June 7 run-off appear likely.The most well-known candidate is conservative Keiko Fujimori, who will make her fourth presidential bid. Her candidacy remains polarizing due to her family legacy, with her father, former President Alberto Fujimori, convicted of human rights abuses and corruption.Other notable candidates include Ricardo Belmont, a former mayor of Lima, and Carlos Alvarez, a popular comedian who has campaigned on a platform of being tough on crime. Peru's homicide rate has more than doubled in the past decade, making crime a major concern for voters.Many Peruvians, however, remain disillusioned with the political system and the available candidates. A fruit seller in Lima told the Reuters news agency that she was still undecided on who to vote for, saying "Peru is a mess, and there's no candidate worth voting for." A clothing merchant also shared similar sentiments, stating "We've been governed by nothing but corrupt, thieving scoundrels."

“The world is grown so bad that wrens make prey where eagles dare not perch,” wrote Shakespeare in *Richard III*. The line now echoes a hopeful development: the iconic golden eagle could once again soar over England after more than a century and a half of absence. The golden eagle, a bird with a wingspan of roughly 2 metres, was a common sight in Shakespeare’s England, yet it has been effectively extinct in the country since the death of the last native individual in 2015. Centuries of persecution by gamekeepers and farmers, who feared predation on lambs and game birds, drove the species to the brink. A feasibility study commissioned by Forestry England and released on Sunday pinpoints eight potential “recovery zones”—predominantly in northern England—where the habitat could sustain a viable eagle population. The report cautions that establishing breeding pairs may take **more than a decade**. In response, Environment Secretary Emma Reynolds announced an additional £1 million in species‑recovery funding. The money will underwrite a programme that could see juvenile eagles, aged six to eight weeks, released into the wild as early as next year. Reynolds said, “This government is committed to protecting and restoring our most threatened native wildlife – and that includes bringing back iconic species like the golden eagle. Backed by £1 million of government funding, we will work alongside partners and communities to make the golden eagle a feature of English landscapes once again.” Across the border, golden eagle numbers in southern Scotland have surged to record levels thanks to a major restoration project. Satellite tracking shows that some translocated Scottish birds are already venturing into northern England, offering a natural source of future colonisers. The new funding will support these cross‑border movements and enable targeted reintroductions. While experts anticipate that golden eagles could be regularly observed across northern England within 10 years, establishing a self‑sustaining breeding population will require a longer horizon. Mike Seddon, chief executive of Forestry England, explained, “The detailed findings of our feasibility study will guide us, with our partners at Restoring Upland Nature, to take the next steps toward recovering golden eagles in northern England. This DEFRA funding means we can build on the good work we have begun, engaging local communities, landowners and conservation organisations.” The £1 million allocation forms part of a broader £60 million species‑recovery fund announced by DEFRA. It aligns with the UK’s legally binding commitment to halt the decline in species abundance by 2030 and to reduce extinction risk by 2042 relative to 2022 levels.

GSK has revealed promising early results for its treatment for gynaecological cancers, Mocertatug Rezetecan (Mo-Rez), as its chief executive, Luke Miels, seeks to speed up drug development at the group.The company reported that in an early-stage trial, Mo-Rez shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer.GSK acquired the Mo-Rez cancer treatment, an antibody-drug conjugate (ADC), from China’s Hansoh Pharma in late 2023, and has trialled it in 224 patients around the world, including the UK, over the past year. Few patients needed to stop treatment because of side-effects, the most common being nausea. It is administered every three weeks via intravenous infusion.Combined with data from a separate, intermediate trial in China, these results give GSK the confidence to go straight to late-stage trials, with five clinical studies planned globally in the next few months, including on patients in the UK.Presenting the results at the Society of Gynecologic Oncology’s annual meeting on women’s cancer in Puerto Rico, Hesham Abdullah, GSK’s global head of cancer research and development, said: “Treatment of gynaecological cancers remains a major challenge, with a pressing need for new therapies that offer improved response rates. With Mo-Rez we now have compelling evidence of a promising clinical profile.”Endometrial cancer affects 1.6 million women globally, with 417,000 new cases each year. Ovarian cancer affects 843,000 people, with 240,000 new cases annually.Abdullah described Mo-Rez as a “key asset” in the company’s growing cancer portfolio, expected to be a blockbuster drug with peak annual sales of more than £2bn, which GSK hopes will help it achieve its 2031 sales target of £40bn.

After serving in Afghanistan, Army Ranger Jesse Gould developed PTSD and turned to drinking to cope. Seeking an alternative to lifelong medication, Gould discovered psilocybin in Peru, which significantly alleviated his symptoms.Gould founded the Heroic Hearts Project, a non-profit hosting ayahuasca and psilocybin retreats for veterans. The organization has helped over 1,500 veterans and their spouses without any psychotic episodes.State lawmakers are taking notice of psilocybin's potential health benefits, with Colorado, New Mexico, and Oregon legalizing it for therapeutic use. At least eight states are considering similar legislation, despite some arguing that the FDA should approve it first.Research suggests psilocybin can be safe and effective when administered with psychological support. A 2025 study found it was associated with symptomatic improvement in adults with PTSD. Clinical psychologist Joseph Zamaria notes that psilocybin can disrupt the brain's default mode network, allowing people to detach from harmful narratives.However, some experts, like Albert Garcia-Romeu, are skeptical about state-led legalization without FDA approval, citing potential unknown risks. Gould counters that the suicide rate among veterans is a pressing issue, with 35 deaths per 100,000 people in 2023, more than double the general population's rate.

Texas is expanding its global reach with the launch of a new office in London, aimed at attracting UK businesses and investment to the low-tax Lone Star State. The office, led by James Taylor, one of the founders of the Austin-based lobbying and public relations firm Vianovo, is part of Texas's efforts to lure corporate heavyweights across its borders.The new site adds to a growing list of international offices from which Texas can try to draw businesses. Texas charges neither corporation nor income tax, making it an attractive destination for companies looking to relocate or expand.Lobbyists working in the London office will court UK bosses with incentives including new, fast-track business courts and multimillion-dollar subsidies. Their targets are expected to include the City's banks and investment houses, as the state aims to build on Dallas's financial-sector boom.The ambitions have caught the attention of the City of London Corporation, with the City's mayor, Susan Langley, discussing how London could tap into excitement over the launch later this year of the state's first dedicated stock market, the TXSE. “With the launch of the Texas Stock Exchange, new dual-listing opportunities could connect British and Texan firms to fresh capital,” she said.The news comes as London tries to reverse a trend where businesses have been abandoning the UK stock market, choosing either to go private or shift their listings to hubs overseas, including New York.Texas has already had success luring jobs and investment from rival US states, including California, Delaware, and New York. Texas has overtaken California in having the largest number of Fortune 500 company headquarters of any American state, with companies like Oracle, Tesla, X Corp, and SpaceX having moved to the state in recent years.A spokesperson for Governor Greg Abbott's office said: “Texas has long had a global presence, with offices in Mexico and most recently in Taiwan designed to attract foreign direct investment and job creation into Texas, while also helping Texas companies export worldwide.”

The recent 10-day space mission of the Artemis II crew has garnered attention, but the true test of endurance might not be in space, but in an office setting. Commander Reid Wiseman, mission specialists Christina Koch and Jeremy Hansen, and pilot Victor Glover spent time in a capsule described as “not much bigger than a family tent”. While they navigated the challenges of confined space, their experience pales in comparison to the complexities of office politics.Anyone who has worked in an office can attest that surviving with colleagues in a confined environment is a significant test of endurance. The Artemis II crew had to get along without time off, which would be challenging even for experienced professionals. The quirks and habits of colleagues can become amplified in such settings, leading to increased tension and stress.The writer of this piece reflects on their own experience in a mundane office job at a stationery firm. They recall the boredom and impotence that led to a fixation on trivial matters, such as a dispute over a window being open or closed. This petty feud became an all-consuming battle that defined their time at the office.The writer notes that, unlike the Artemis II crew, they had the option to leave the office at the end of the day. However, their obsession with the window dispute led them to spend more time at their desk, avoiding breaks and social interactions. The comparison between the crew's space test and the writer's office experience highlights the universal challenges of working with others.Ultimately, the Artemis II crew's achievement is impressive, but it also underscores the importance of interpersonal skills and conflict resolution in any confined or high-stress environment. As the writer concludes, surviving an office job can be just as challenging as surviving in space.

The discussion centers on the complex calculus behind forging a permanent ceasefire between the United States and Iran. Analysts consider whether sustained diplomatic pressure, strategic incentives, and the potential fallout from missteps can collectively drive the parties toward a conclusive settlement. Pressure tactics—including sanctions relief and political engagement—are examined for their ability to compel concessions, while incentive packages such as economic aid or security guarantees are weighed as possible carrots. Equally critical are the risks involved: misinterpretation of signals, regional power dynamics, and domestic opposition on both sides could derail negotiations. The piece underscores that any viable deal must balance these elements to achieve durability and broader regional stability.

Celtic overtook rivals Rangers to sit second in the Scottish Premiership after a narrow 1‑0 win against St Mirren, while Hearts preserved their lead at the top with a late‑filled 3‑1 triumph over Motherwell.At Celtic Park, Alex Oxlade‑Chamberlain broke the deadlock in the 15th minute. After a blocked attempt from Benjamin Nygren, Kieran Tierney delivered a precise cross that Oxlade‑Chamberlain struck into the bottom corner, giving Celtic a comfortable first‑half advantage.St Mirren dominated possession in the second half but failed to create clear chances, allowing Celtic to hold onto the solitary goal.The encounter marked the first meeting between the sides since St Mirren’s surprise 3‑1 cup win over Celtic in December, a result that proved difficult to repeat.For the first time since November, the Green Brigade were welcomed back to Celtic Park, adding a vibrant backdrop to what many view as a dress rehearsal for next week’s Scottish Cup semi‑final.At Tynecastle, Motherwell took an early lead through Emmanuel Longelo. Hearts responded quickly when Cláudio Braga equalised with an overhead kick. The match seemed poised for a draw until Lawrence Shankland converted a penalty after Stephen Welsh was judged to have fouled Landry Kaboré. Kaboré then added a third in stoppage time, sealing the three‑point win for Hearts.In the north, Stephen Robinson ended his winless streak since moving from St Mirren to Aberdeen, guiding his side to a 2‑0 victory over Hibernian at Pittodrie, with Kevin Nisbet scoring in each half.At Tannadice, Zac Sapsford rescued Dundee United with a late penalty, completing a dramatic 3‑2 comeback against Livingston. The hosts had led through a first‑half goal by Will Ferry, but Livingston responded with a quickfire double from Lewis Smith before United equalised via substitute Krisztian Keresztes.Meanwhile, Kelle Roos produced a crucial stoppage‑time penalty save against Dundee striker Joe Westley, earning Kilmarnock a vital point in their relegation battle. The decision followed a lengthy VAR check that delayed the penalty by six minutes.Kilmarnock’s earlier clash with Dundee saw a roller‑coaster finish: Joe Hugill opened the scoring, Simon Murray equalised for Dundee, Michael Schjønning‑Larsen restored the lead for Kilmarnock before Scott Wright’s late goal forced extra‑time drama.