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Eli Lilly, the US pharmaceutical group behind the Mounjaro weight-loss drug, is seeking to resume its investments in the UK after pausing them last year. The company is in talks with UK ministers to regularly increase NHS drug prices and end a rebate scheme. Patrik Jonsson, president of Eli Lilly's international business, expressed optimism about reaching an agreement this summer.The talks will also explore 'innovative' pricing plans, such as linking payments for anti-obesity drugs to whether the treatment helps patients return to work. This comes as the US pharmaceutical industry increases pressure on the UK, with Keir Starmer agreeing to the first increase in NHS cost-effectiveness thresholds in 27 years. The threshold was raised from £20,000 to £30,000 a year for every year of life gained to £25,000 to £35,000.Eli Lilly was one of several pharmaceutical companies that ditched or paused almost £25bn in planned investments in the UK last year. The company paused its plans to invest in a laboratory site in central London. Jonsson stated that the resumption of Eli Lilly's investment would depend on the outcome of its talks with the government.He emphasized that prices for medicines in the UK had been 'far too low for far too long' and that the threshold couldn't remain static for another three decades. The UK agreed to pay 25% more for new medicines by 2035 as part of a US-UK drug pricing deal, which could eventually reach £9bn a year.Large pharmaceutical companies have protested about a 'rebate' scheme, under which they are required to pay back a chunk of revenue from sales of branded medicines. This scheme is expected to fall in 2026, although Jonsson believes payments 'should actually get down to zero' over time.

A recent survey conducted by the Football Supporters' Association has revealed that 91% of football fans believe the game is better off without Video Assistant Referees (VAR). The survey, which polled over 7,000 fans, found that the vast majority of respondents are dissatisfied with the VAR system, which has been in use for over eight years.The survey results show that only 2% of fans agree that VAR makes football more enjoyable, while 3% said it improves the experience of attending a match. In contrast, 81% of fans prefer watching matches without video technology. The survey also found that 96% of fans disagree with the statement that VAR decisions are generally resolved in a reasonable amount of time.While some fans approve of the introduction of in-stadium communication from referees to explain VAR decisions, other extensions of the VAR protocol were largely unpopular. For example, only 21% of fans agreed that VAR should adjudicate on whether corner kicks are awarded, a system set to be trialled at this summer's World Cup.The survey results may not necessarily influence the game's decision-makers, as competition organisers and big clubs are committed to the use of VAR. However, the International Football Association Board (Ifab) has announced a two-year review into the system's performance, which may lead to changes in how VAR is used.

Leicester City Women are staring down the barrel of relegation to the second tier after a disheartening 1-0 loss to Brighton in the Women's Super League. The defeat, which came on a soggy afternoon at the King Power Stadium, has left them four points adrift at the bottom of the table with only four games remaining.The sight of two young girls proudly waving 'Foxes never quit' flags in the rain-soaked stands encapsulated the never-say-die attitude required for a relegation battle that Leicester now finds itself in. Despite the bleak outlook, manager Rick Passmoor and the fans remain optimistic about their chances of survival.The latest setback came against Brighton, who showed their class on the ball, particularly in the first hour. Fran Kirby's movement and creativity caused significant problems for the Leicester defense. The decisive moment arrived when Kiko Seike broke the deadlock by tucking home Rosa Kafaji's unselfish pass, following a sublime through ball from Kirby.Leicester's struggles this season can be attributed largely to operating on what is believed to be the lowest budget in the top tier, compounded by the loss of key players such as Ruby Mace and the Japan duo Saori Takarada and Yuka Momiki last summer. The team is on a seven-match losing run in the league, which has coincided with Liverpool's significant upturn in results following their January transfer activity.There is still a potential lifeline for Leicester in the form of a one-leg playoff fixture against the third-placed team in the second tier, scheduled for May 23. However, their opponents have yet to be determined, with Crystal Palace and Birmingham keeping the automatic promotion race on a knife-edge.The women's predicament comes at an uncertain time for the football club as a whole, with the men's team in the Championship relegation zone, a point from safety after being deducted six points for overspending. It could yet be a campaign to forget for both the men's and women's sides.

The Iranian men's national football team made a poignant gesture before their friendly match against Nigeria in Turkey, wearing black armbands and posing with pink and purple school bags with ribbons on them. This powerful display was a tribute to the victims of a devastating air strike on a primary school in Minab, Iran, which occurred on the first day of the Middle East war on February 28. The air strike killed at least 170 people, including students and teachers. The attack happened on the day the United States and Israel launched the war with attacks across Iran. Iran's foreign minister accused the US of a "calculated, phased assault" on the school. According to The New York Times, preliminary findings of a US military investigation indicate that a US Tomahawk cruise missile hit the school due to a targeting mistake. The US military had been bombing an adjacent Iranian base, of which the school building was formerly a part, using outdated data to set the target coordinates. US President Donald Trump initially suggested that Iran itself may have been responsible for the attack, despite the country not having Tomahawk missiles. The incident has added to the tensions between Iran and the US, with Iran qualifying for the World Cup finals this summer but asking for its matches to be moved from the US to Mexico due to concerns over player safety. In the friendly match, Iran lost 2-1 to Nigeria. The team's gesture was a powerful reminder of the human cost of conflict and the impact on innocent civilians, particularly children.

Cambridge University is launching a four-week summer course in botany, inspired by a course taught by Prof John Stevens Henslow to Charles Darwin in the 1820s. The course will use original teaching materials, including plant specimens and illustrations, to teach students about botany.The course aims to address the gap in botany education in the UK, where the subject has largely disappeared as a standalone degree. Dr Raphaella Hull, acting head of learning for Cambridge University Botanic Garden, said that the course will teach students about botany using hands-on techniques and field excursions.The course is based on Henslow's pioneering approach to teaching botany, which emphasized the importance of observing and understanding plant diversity. Henslow's use of illustrations on his course was groundbreaking, and he is credited with influencing Darwin's later theory of evolution.Prof Sam Brockington, curator of Cambridge University Botanic Garden, said that the course is designed to be an immersive program in botany, and that Henslow's approach to teaching botany is still relevant today.

The reintroduction of beavers in Dorset has shown promising results, with the animals building a 35-metre dam and creating a deep, wildlife-rich pool. By coppicing trees, they have allowed more light in and improved habitats for plants, insects, amphibians, birds, and bats.Trail cameras have captured footage of an otter fishing in the pond, as well as a barn owl hunting there. Volunteers have spotted birds including redpolls and water rails. The cameras also captured footage of two of the beavers mating, indicating they have settled in their new home and that there could be kits this summer.Despite some hitches, including the death of a male beaver and the relocation of a female, the western pair of beavers has been busy doing their engineering work. The National Trust, which is in charge of the project, said it was thrilled with the progress, highlighting the astonishing effect on the ecosystem in a relatively short time.Gen Crisford, the National Trust's wetlands project officer, said setbacks were inevitable but expressed hope for a 'happy ever after moment' with the western pair. The project allows for the release of 10 to 25 adult beavers, with the next release expected to take place this autumn.

Thomas Tuchel, the England head coach, voiced his disappointment with the Wembley crowd's reaction to Ben White's return to international football during the 1-1 draw with Uruguay. White was booed upon his substitution in the 69th minute, a reaction Tuchel found disheartening.The game was marked by controversy, including a painful tackle by Ronald Araújo on Phil Foden that escaped a red card and an injury to Noni Madueke. Tuchel was also critical of the refereeing, particularly the decision to award Uruguay a penalty for a soft foul by White.“I heard that he was booed,” Tuchel said of White. “It cannot be the majority. There were some boos and some mixed reception for him which I’m disappointed about because of course we protect our players. He was excellent in camp and he deserved to come on. He got us almost a winner.”Tuchel praised his side's effort but focused his anger on the German referee Sven Jablonski, expressing confusion over the VAR's inconsistent application. The draw was a mixed result for England, who were without several regular players and are preparing for the World Cup this summer.

The Rugby Football Union (RFU) has stopped short of fully backing Steve Borthwick as England's head coach for the upcoming Nations Championship fixtures. However, RFU CEO Bill Sweeney emphasized that their primary focus is on supporting the existing coaching team.Sweeney's comments suggest that Borthwick is likely to lead England in their summer Test matches against South Africa, Fiji, and Argentina, pending the outcome of a formal review into their disappointing Six Nations campaign. The review aims to identify areas for improvement and provide additional support to the coaching team.A key point of interest is the absence of discussions with Andy Farrell, the Ireland head coach, whose contract expires after the 2027 World Cup. Farrell has a strong track record, having led Ireland to two Six Nations titles and a successful Lions tour. Sweeney confirmed that there are 'no approaches' to Farrell and that their focus remains on supporting Borthwick.The RFU's review process is expected to conclude by the end of April. Potential changes or additions to Borthwick's backroom team are being considered, including the possibility of creating a new general manager role similar to that of Rassie Erasmus with South Africa.England's upcoming fixtures pose significant challenges, particularly against South Africa in Johannesburg. The team will also face logistical hurdles with matches against Fiji and Argentina, including a long travel schedule.

Roy Hodgson has made a sensational return to management at the age of 78 with Bristol City, following the sacking of Gerhard Struber by the Championship club. Hodgson, who has been out of work since leaving Crystal Palace in February 2024, will take charge of City for the remaining seven games of the season. They are currently 16th in the Championship.Hodgson's storied managerial career in England began at Ashton Gate in 1982, after a period at Swedish club Halmstad. In total, he has managed 17 different clubs and four different international sides, including England, from 2012-16. “I have had great conversations with the board and I am really excited by the opportunity to help until the end of the season,” he said. “We will get straight to work and look for a positive performance [against Charlton] on Good Friday.”The appointment comes after Struber, who succeeded Liam Manning last summer, had grown frustrated at the club and voiced his disappointment at the January window, when City sold key players Anis Mehmeti and Zak Vyner to division rivals Ipswich and Wrexham respectively. Struber’s assistant Bernd Eibler has also departed. Results under the Austrian tailed off, with Struber winning only one of his final nine matches in all competitions.“Roy’s appointment is about more than the results of the next seven games,” said the Bristol City chief executive Charlie Boss. “Over the remainder of the season, he will help us set the standards and values at the club that we will need to be successful going forwards. Roy is a vastly experienced coach who has achieved and won at the highest level.” City are in the process of recruiting an incoming sporting director who will help appoint a permanent head coach expected to replace Hodgson at the end of the season.