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Israel's attacks on Lebanon have intensified, with the country launching its largest and most destructive attack on Lebanon in years, killing at least 300 people and wounding over 1,100. The attacks have sparked widespread panic and overwhelmed hospitals in the Lebanese capital, Beirut.The escalation has significant implications for the US-Iran ceasefire, which was agreed upon just days ago. Iranian leaders are accusing the US of failing to uphold the truce and threatening to back out of it unless Washington restrains its ally, Israel. 'The U.S. must choose – ceasefire or continued war via Israel. It cannot have both,' Iran's foreign minister, Abbas Araghchi, wrote on Twitter/X.The conflict has been fueled by Netanyahu's actions, who has sought to expand the conflict out of Gaza and into a wider war with Hezbollah in Lebanon. The Israeli prime minister has undermined ceasefire talks and blocked potential deals, adding new conditions or changing his mind at the last minute. 'There is no ceasefire in Lebanon,' Netanyahu said in a recorded message, as Israel continued its attacks.The situation is volatile, with Hezbollah showing it is not as weak as Israel and the US had thought. The militia has fought pitched battles with invading Israeli troops and fired hundreds of rockets and drones at northern Israel. The conflict has forcibly displaced over 1.1 million people, many of whom are living on the streets.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

The recent two-week ceasefire announced by US President Donald Trump in the war on Iran has sent shockwaves through Israel. The move has been met with criticism from Israel's opposition leader, Yair Lapid, who called it one of the greatest 'political disasters in all of our history'. Prime Minister Benjamin Netanyahu's office issued a statement supporting the US decision, claiming that 'Iran no longer poses a nuclear, missile and terror threat to America, Israel, Iran's Arab neighbours and the world.' However, Netanyahu's war aims of preventing 'Iran from developing nuclear weapons' and creating 'the conditions for the Iranian people so they can remove the cruel regime of tyranny' remain unachieved.Despite significant military successes over the past 40 days of attacks on Iran, neither of Netanyahu's goals has been achieved. The Iranian regime is still in place, its ballistic missile programme could be rebuilt quickly, and it still has 440kg of enriched uranium at 60 percent purity, enough for 10 bombs.Analysts say that Iran has emerged stronger as a result of the war, with key victories including the survival of the Iranian government and its decision to close the Strait of Hormuz, one of the world's key energy arteries. The ceasefire has also given Iran an opportunity to continue with newly imposed levies on ships for safe passage through the Strait.Criticism of Netanyahu's handling of the war has been swift, with Ofer Cassif of the left-wing Hadash party saying that the prime minister has 'failed politically, failed strategically, and didn't meet a single one of the goals that he himself set'. Ahron Bregman, a senior teaching fellow at the Department for War Studies at King's College London, said that 'Israel achieved almost nothing tangible' and that the ceasefire has 'strained the US relationship'.

Celebrations erupted in Tehran after officials announced a two‑week ceasefire with the United States, creating a window for diplomatic talks aimed at de‑escalating the regional conflict.Iran consented to suspend hostilities, with negotiations slated to begin on Friday in Pakistan. President Donald Trump pledged to halt military operations provided Tehran fully reopens the Strait of Hormuz, a vital maritime corridor. Iran’s foreign minister added that safe passage through the strait will be coordinated with Iranian armed forces throughout the truce.The breakthrough followed a direct appeal by Pakistan’s Prime Minister Shehbaz Sharif, who urged Trump to extend his negotiation deadline and called on Iran to restore strait access.Iranian officials framed the ceasefire as a “victory”, asserting that their preconditions for talks were accepted and that Trump’s acknowledgment of progress on key disputes validates Tehran’s stance. They emphasized that national unity, patience, and military resilience were decisive factors.In their assessment, the earlier U.S.–Israeli strategy of targeting Iranian leadership failed, while the ensuing conflict demonstrated Iran’s capacity to sustain prolonged military operations.Trump, speaking to AFP, described the agreement as a “total and complete victory”, insisting that Iran’s uranium stockpiles would be “perfectly taken care of” under the deal and crediting China for facilitating the negotiations.Despite the truce, Democratic lawmakers announced they will continue impeachment efforts against Trump, condemning his rhetoric toward Iran as “genocidal” and “unhinged.”

The administration has confirmed a two‑week suspension of any imminent strikes on Iran, signaling a short‑term pause in hostilities. This move reflects a tentative step toward reducing immediate tensions, though officials did not elaborate on the conditions that would trigger a resumption of operations.

A union representing roughly 2,000 food‑service employees at Los Angeles Stadium has formally appealed to FIFA to ensure that U.S. Immigration and Customs Enforcement (ICE) stays away from World Cup activities in the city. Unite Here Local 11, which covers cooks, servers and bartenders at the Inglewood venue, warned that a strike could become imminent if its concerns are ignored. The union highlighted that its members are still without a labor contract as the tournament approaches, and outlined three core demands for FIFA and stadium owner Kroenke Sports & Entertainment: A public pledge that ICE and Border Patrol will have no role in any World Cup‑related operations. Guarantees protecting union jobs, working conditions, and a ban on the use of artificial intelligence or automation that could displace workers. Support for a workforce‑housing fund, stricter short‑term‑rental rules, and tax measures aimed at financing affordable housing and protecting immigrant families. ICE Acting Director Todd Lyons has indicated that the agency would play a “key part” in the event, a prospect the union says threatens the safety of both workers and visitors in Los Angeles. “FIFA and its corporate sponsors will pocket billions from Los Angeles while refusing to even acknowledge the cooks, servers, and stand attendants who make this event possible,” said Kurt Petersen, co‑president of Local 11 in a statement. Local 11 also noted that it has repeatedly sought meetings with FIFA since the city was awarded hosting duties, but its requests have been ignored. The venue, known globally as SoFi Stadium, has been temporarily rebranded as Los Angeles Stadium for the World Cup due to sponsor conflicts. The stadium is slated to host eight matches, with the opening game – the United States versus Paraguay – scheduled for June 12. The union’s broader housing demands reflect rising living‑cost pressures in Inglewood and the surrounding Los Angeles area, underscoring the intersection of labor rights, immigration policy, and urban affordability ahead of the global tournament.

Tens of thousands of people have been hired by Scale AI – a firm 49% owned by Meta – to train artificial‑intelligence models by scraping Instagram accounts, harvesting copyrighted artwork and transcribing pornographic soundtracks, according to the Guardian.Scale AI promotes its Outlier platform as a flexible, expert‑driven marketplace, recruiting professionals from medicine, physics and economics to "become the expert that AI learns from."Workers, however, say the reality diverges sharply from high‑level model refinement. They describe tasks that involve massive personal‑data scraping and content that many find morally uncomfortable.Outlier is managed by Scale AI, which holds contracts with the U.S. Pentagon and other defense companies. Its chief executive, Alexandr Wang, is hailed by Forbes as the world’s youngest self‑made billionaire, while former managing director Michael Kratsios served as science adviser to former President Donald Trump.One contractor noted that users of Meta platforms would be shocked to learn their photos and friends’ images are being harvested for AI training, with workers manually reviewing profiles to extract data.The Guardian interviewed ten Outlier contributors – many also journalists, graduate students, teachers or librarians – who took the gig work out of economic desperation. One said, "A lot of us were really desperate" and felt compelled to accept the unstable, low‑pay assignments.These gig workers, dubbed “taskers,” often feel they are training their own replacements, expressing “internalised shame and guilt” over contributing to the automation of creative professions.Law firm Clarkson, representing AI gig workers, estimates that hundreds of thousands of people worldwide now labor on platforms like Outlier. Taskers report bait‑and‑switch recruitment tactics, where advertised high salaries are replaced by lower‑paid projects after onboarding.All contributors are monitored through a tool called Hubstaff, which can screenshot browsers to verify work. While Scale AI claims the software is only for accurate payment, workers describe it as constant surveillance.Assignments have ranged from transcribing pornographic audio and labeling photos of dead animals or dog faeces, to annotating diagrams of infant genitalia and violent police scenarios. One doctoral student recounted being promised “no nudity” only to receive explicit porn clips.Scale AI says it shuts down any task flagged as inappropriate and does not accept projects involving child sexual‑abuse material or pornography, though workers note that publicly available images of minors have been used for training.Social‑media scraping tasks required workers to tag individuals by name, location and age, sometimes pulling data from accounts of users under 18. One task asked contributors to order Facebook photos by the subject’s age, prompting ethical unease.In addition to personal data, taskers were asked to harvest copyrighted artwork, with strict instructions to avoid AI‑generated images and select only hand‑drawn pieces. Scale AI maintains it does not ask workers to violate copyright standards.Scale AI’s client list includes major tech firms such as Google, Meta and OpenAI, as well as the U.S. Department of Defense and the government of Qatar, highlighting the growing demand for labelled data as AI models scale.Some workers reported interacting with ChatGPT and Claude, and speculated they might be training Meta’s upcoming model, code‑named “Avocado.”OpenAI announced it ended its partnership with Scale AI in June 2025, citing its supplier code of conduct that mandates ethical treatment of all workers.Despite irregular pay, occasional mass layoffs and the unsettling nature of many tasks, many taskers remain on the Outlier platform, hoping the AI future will eventually improve conditions. One said, "I have to be positive about AI because the alternative is not great."In response, a Scale AI spokesperson stated, "Outlier provides flexible, project‑based work with transparent pay. Contributors choose when and how they participate, and we regularly hear from highly skilled contributors who value the flexibility and opportunity to apply their expertise on the platform."

In the hills of Mount Lebanon, a school has been transformed into a shelter for families displaced from southern Lebanon due to Israeli attacks. The schoolyard, once filled with students, is now a hub for aid deliveries, with empty swings and slides a stark reminder of the disruption to daily life.Families like Aymane Malli's have fled their homes, seeking safety in the mountains. Malli, a 49-year-old father of five, described the traumatic experience of leaving his home in Habbouch, near Tyre, after Israel began bombing Lebanon on March 2. 'It's very difficult,' he said, 'but for me, it's OK because I have to survive. I have to take care of my family.'The humanitarian situation is dire, with over 1.1 million people forced from their homes and more than 1,300 killed, including 120 children. Aid groups, such as Action Against Hunger, are struggling to provide support, with over 400 people turned away from the Qabr Chamoun school due to overcapacity.Conditions in shelters are deteriorating, with water leaks, gastrointestinal illnesses, and eye infections reported. The destruction of key infrastructure, particularly bridges and access routes, is exacerbating the crisis, making it difficult for families to flee and for aid to reach them.The future remains uncertain for these displaced families, with concerns about long-term food security and the possibility of a prolonged Israeli security presence or occupation in southern Lebanon. As Mohammed al-Mustafa, a sweets seller from Tyre, poignantly noted, 'It's not the material things I worry about leaving behind. It's the memories. We lived in that house for 40 years. Old photographs, our lives.'

Scientists have made a groundbreaking discovery, identifying a distinct 'neural fingerprint' produced by psychedelic drugs in the human brain when users experience their mind-altering effects.This breakthrough finding emerged from a comprehensive study that combined 11 brain imaging datasets from around the world, involving over 500 brain scans from 267 people in five countries. The research focused on five psychedelic substances: LSD, psilocybin, DMT, mescaline, and ayahuasca.The study revealed that these substances have a shared impact on the brain's behavior, dissolving the usual hierarchy of brain systems and flattening the hierarchy, which may underlie the raw access to one's own consciousness that some people describe during psychedelic experiences.Dr. Danilo Bzdok, a senior author on the study from McGill University in Montreal, Canada, explained that all five drugs change brain function in common ways, despite some differences in how they alter brain activity. The most striking effect was stronger communication between brain networks that engage in higher-level thinking and more primitive networks linked to vision and sensation.The research, published in Nature Medicine, provides a solid foundation for psychedelic research, which is crucial if these drugs are to become widespread therapies for mental health conditions such as depression, schizophrenia, and post-traumatic stress disorder.Dr. Emmanuel Stamatakis, a senior co-author on the study from the University of Cambridge, emphasized the importance of large-scale, coordinated evidence in the field of psychedelic research, which is moving quickly and needs to mature responsibly.