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Phil Foden must seize his chance as Manchester City face Liverpool on Saturday at 12:45 pm BST. After two lacklustre starts for England under Thomas Tuchel, the 25‑year‑old has recorded only one assist in his last 22 outings for club and country. Dropped below Rayan Cherki in Pep Guardiola’s hierarchy and yet to complete a full 90 minutes since January, Foden’s performance in the FA Cup could determine his future at both City and the national team.Manchester City v Liverpool – Saturday 12:45 pm BSTEstêvão Willian offers Chelsea a welcome boost. Following a Champions League exit at the hands of Paris Saint‑Germain and a heavy defeat to Everton, manager Liam Rosenior faces a must‑win against Port Vale at 5:15 pm BST. The 18‑year‑old Brazilian winger, who impressed as a substitute against Everton, could inject the speed and unpredictability Chelsea need to lift a disgruntled crowd and revive a faltering season.Chelsea v Port Vale – Saturday 5:15 pm BSTKepa Arrizabalaga gets a second chance ahead of Arsenal’s trip to Southampton. The former Athletic Bilbao keeper was at fault for the decisive goal in the Carabao Cup final, yet manager Mikel Arteta has kept him as the starting goalkeeper for the FA Cup tie. A solid performance could cement Arrizabalaga’s status as Arsenal’s long‑term No 2, while a repeat error may see him lose the role to David Raya.Southampton v Arsenal – Saturday 8:00 pm BSTWest Ham’s cup run doubles as a survival rehearsal. The Hammers host Leeds United on Sunday at 4:30 pm BST, a match that could swing the relegation battle. Despite a recent victory over Brentford, injuries – notably to winger Crysencio Summerville – threaten to undermine their league campaign. Manager Nuno Espírito Santo must balance the morale boost from the cup with the need to keep key players fit for the Premier League’s final stretch.West Ham v Leeds – Sunday 4:30 pm BST

The blockade of the Strait of Hormuz has raised concerns about a potential global food crisis due to its impact on fertiliser supplies. The strait is a critical passage for 20% of global natural gas shipments and a third of the global trade in raw materials for fertiliser.The head of the International Rescue Committee, David Miliband, has warned that the situation is a 'food security timebomb', with the window to avert a massive global hunger crisis rapidly closing.Fertiliser prices have already risen by more than 60% in Egypt, reaching $780 (£586) a tonne, up from about $484 in late February. The Qatar Fertiliser Company (QAFCO), the world's largest single site for urea exports, has been offline for almost a month.The Middle East is the source of about 45% of the global trade in sulphur, a key raw material for fertiliser manufacture. Iran is the fourth-largest global exporter of urea, the most widely used nitrogen fertiliser.A prolonged transport shutdown could disrupt production and increase costs, leading to higher food prices and exacerbating global hunger. The world's poorest countries are among the most vulnerable to fertiliser price rises.

The ongoing closure of the Strait of Hormuz, a crucial oil and gas shipping route blocked by Iran since the US-Israeli attacks began, is having ripple effects around the world. If the strait remains closed, transport blockages across the Middle East could cause significant shocks to food and medicine supplies in the UK.UK Foreign Secretary Yvette Cooper is hosting a meeting with 35 other countries to discuss reopening the strait. Experts warn that a prolonged closure could lead to food price inflation doubling in England and medicine shortages due to disrupted supply chains.Impact on Food SuppliesProf Tim Lang from City St George's, University of London, warns that 'all bets are off' for food supplies if the crisis continues. Rising fossil fuel prices will impact food transportation and production, as fuel is used to transport food and produce fertilizers and other inputs.The farming sector is already facing problems, with dairy production hit due to delayed fertilizer purchases and salad vegetable and dairy producers facing disruptions. Iranian imports like pistachios and saffron are also affected.Impact on Medicine SuppliesWhile there's no hard evidence of medicine shortages yet, price increases are being seen, which can signal disruptions in the medicine supply chain. Iran does not manufacture many medicines but affects the sector through rising energy costs and transport links between major pharmaceutical-producing countries and the UK.David Weeks from Moody's notes that shortages are driven by delays in petrochemical precursors for active pharmaceutical ingredients. Medicine stockpiles in European countries, including the UK, can last up to six months, but long-term conflicts could lead to more severe shortages.

A blinking fault light on NASA’s Orion spacecraft signalled a malfunction in the Universal Waste Management System (UWMS) just as the historic Artemis II crew began their 10‑day lunar‑orbit mission. Mission control reported the issue was resolved within minutes, stating: “Happy to report that toilet is go for use. We do recommend letting the system get to operating speed before donating fluid, and then letting it run a little bit after donation.”The $30 million (≈£22.6 million) UWMS, years in development, is hailed as a breakthrough in deep‑space sanitation, dramatically improving on the primitive setups used during Apollo. Back then, astronauts used a condom‑like urine collector and a bagged solid‑waste system that was prone to leaks and even produced “a turd floating through the air,” according to mission transcripts.Orion now features a private toilet cubicle – the first of its kind on a space shuttle – accessed through a floor hatch beside the main entry hatch. Handrails and foot tethers keep the crew anchored while inside.“We’re pretty fortunate as a crew to get a toilet with a door on this tiny spacecraft,” noted Jeremy Hansen of the Canadian Space Agency in a pre‑launch video. “The one place during the mission where we can go and actually feel like we’re alone for a moment.”The system uses a funnel attached to a hose for urine and a small seat for solid waste. Because everything floats, faeces are suctioned into a sealed bag at the bowl’s base and then compressed into a canister. The suction is loud enough that the cubicle is insulated and crew members must wear ear protection while using it.On longer stays, such as ISS missions, astronauts now recycle almost all liquid waste, turning urine and sweat into drinkable water. For the short Artemis II flight, urine will be vented daily and solid waste stored for disposal after return to Earth.Beyond comfort, the upgraded toilet is a mission‑critical component for NASA’s goal of a permanent lunar presence. Sustainable waste handling prevents health risks and avoids contaminating the pristine space environment with Earth microbes. As historian David Munns explained, “Actually thinking about not only toilets but the entire life‑support systems is one of the foundations of long‑term living in space.”

TikTok announced the removal of a high‑profile Israeli far‑right influencer’s account after The Guardian identified videos in which he assaulted left‑wing activists in the occupied West Bank. The platform said the content breached its community guidelines on hate speech and bullying. The influencer, identified as Roi Star, posted footage in January showing himself entering a house used by activists in Ras Ein al‑Auja and using pepper spray on a protester who tried to stop him. In the same clip, he shouted, “This is Judea, not Palestine,” and later threatened to disclose personal details of the activists and their families. When contacted, Star claimed he was “talking about peace” and argued that the area was an open Israeli public space, insisting that his use of pepper spray was the “most minimal” defensive measure. He later described the incident as “acting” and said his intentions were not “extreme.” TikTok’s statement emphasized that its policies prohibit “violent and hateful individuals, including extremist praise or glorification,” and that the account was taken down for breaching these rules. The company also said it had removed additional videos linked to other Israeli far‑right agitators, though it did not disclose further details. The incident occurs against a backdrop of rising far‑right activity on social platforms since the Gaza war began in October 2023. Israeli forces and settlers have been responsible for the deaths of over 1,000 Palestinians in the West Bank, and recent weeks have seen an escalation of attacks on homes and activists. Human‑rights groups warn that the online amplification of such content fuels real‑world violence. Yuli Novak, executive director of B’Tselem, said dehumanising Palestinians has become “mainstream in Israel,” while digital‑media scholar Prof. Anat Ben‑David highlighted the “troubling convergence between platform dynamics and on‑the‑ground violence.” Activists on the ground report a profound psychological impact, with one resident of Masafer Yatta noting that the videos heighten fear among Palestinians living under daily settler attacks. The phenomenon mirrors the rhetoric of Israel’s far‑right politicians. In August 2025, National Security Minister Itamar Ben‑Gvir faced criticism for posting a video taunting Palestinian leader Marwan Barghouti, while Knesset member Zvi Sukkot was filmed denying settler violence in the West Bank, framing the settlement enterprise as a biblical right. Meta’s Instagram continues to host numerous accounts linked to similar agitators, though the company has not responded to requests for comment. Experts argue that while platform policies technically forbid hate‑speech, their vague language allows harmful content to spread unchecked, underscoring the need for stronger enforcement to curb the digital propagation of extremist narratives.

Italy awoke on Wednesday in a state of anger and disbelief after the Azzurri were eliminated from the FIFA World Cup 2026 qualification by a 4-1 penalty shoot‑out defeat to Bosnia and Herzegovina, following a 1‑1 draw in regular time.The loss represents the third straight playoff elimination for Italy – previous setbacks came against Sweden and North Macedonia – and has revived what the front page of Corriere della Sera dubbed the "World Cup curse."Italian media, including La Gazzetta dello Sport and Corriere dello Sport, echoed the sentiment with headlines proclaiming “We’re all staying at home,” underscoring the depth of national disappointment.Key moments in the match included a red card for Alessandro Bastoni in the 42nd minute for a last‑man tackle, a turning point that shifted momentum despite Italy leading at the time.Fans expressed their shock and frustration: "Everything went badly from the start of the match. The team wasn’t good, players out of form… it makes no sense," said Davide Caldaretta, a spectator in a Rome pub, to Reuters.Melanie Cardillo, also speaking to Reuters, described herself as “really upset and disappointed,” adding that the repeated failures have eroded hope.Beyond football, Italy recently celebrated a record 30 medals at the Milan‑Cortina Winter Olympics and 40 medals at the 2024 Paris Summer Games, highlighting the country's broader sporting prowess, from speed skater Francesca Lollobrigida to tennis champion Jannik Sinner.Nevertheless, the football debacle prompted a political backlash. Sport Minister Andrea Abodi called on FIGC President Gabriele Gravina to resign, stating, "Italian football needs to be rebuilt from the ground up, starting with changes at the top of the FIGC."Gravina refused to step down, noting that a board meeting next week will determine his future. Tensions have risen between the government and the federation, with Gravina accusing the state of treating football as a "state sport" while favoring other disciplines.Former Prime Minister Matteo Renzi weighed in, calling the elimination “unfortunately not an April Fool’s joke” and emphasizing that football is integral to Italy’s cultural identity.In response to Gravina’s remarks, speed skater Francesca Lollobrigida posted sarcastically on Instagram, "I’m an amateur," underscoring the broader debate over responsibility for the missed qualification.As Italy prepares for the next board meeting, the nation faces a pivotal moment: whether to overhaul its football governance or continue grappling with a perceived "curse" that has kept the Azzurri out of the world stage for three consecutive cycles.

The families of British citizens held in the United Arab Emirates over allegations that they shared images of the conflict with Iran have expressed frustration at the British government's failure to help.Several British citizens are among more than 100 foreign nationals who have been detained under draconian Emirate rules that outlaw publishing or sharing material that could 'disturb public security'.UK government ministers have refused to condemn the arrests, amid claims they are too fearful of offending the Emirates because of their economic clout.The campaign group Dubai Watch, which is supporting nine British detainees, said their identities could not be revealed for fear of reprisals. But it has shown the Guardian anonymised correspondence from their increasingly anxious families.A mother whose daughter is being held wrote: 'This experience is exhausting, mentally and emotionally.'She described reading media reports about the continuing conflict in which Iran has retaliated against US and Israelis strikes by firing drones and missiles against its Gulf neighbours, including the UAE.She said: 'I have just read another article, and quite frankly I could do one purely on the inadequacies and sycophantic responses from this [UK] embassy.'She also expressed increasing fears for her daughter's safety as attacks continued. The mother said: 'I spoke to [my daughter] last night and they are no longer allowed to go outside in the courtyard as it's now deemed too dangerous to do so. This is an even bigger worry as they are all just sitting ducks.'Another message from a woman whose husband had been detained under the same law said the case had been 'mishandled'. She added: 'We are scared because nobody is telling us the truth. Can you please help us.'Police in Abu Dhabi said those detained had 'filmed sites and events and disseminated inaccurate information via social media platforms during the ongoing events, an action that could stir public opinion and spread rumours among community members'. In a statement, the officials said these 'violations' amounted to a 'misuse of social media'.Daisy Cooper, the deputy leader of the Liberal Democrats, confirmed that one of the detainees was a St Albans' constituent. She said their family was frustrated by the lack of consular help.Cooper told the Guardian: 'I'm deeply concerned that my constituent has been held with very little contact with their family, with no clear access to legal counsel, and no confirmation that UK consular officials have been permitted to visit them. The family are distressed and desperate for information about their wellbeing.'Cooper also criticised the UAE's round-up of anyone it has accused of sharing images of the conflict. She said: 'The response from the authorities appears wholly disproportionate given the nature of the allegations.'The Foreign, Commonwealth and Development Office confirmed that five UK nationals were receiving consular assistance in the UAE.David Haigh, a human rights lawyer and founder of Dubai Watch, said: 'There's an awful lot more than five cases. The embassy is overwhelmed.'He added: 'There hasn't been any government intervention because it would offend the UAE and they don't want to do that. Impotent is the best way to describe the response. They're too scared – it's all about the money and investment from the UAE.'

The U.S. Food and Drug Administration announced on Wednesday that it has granted expedited approval to Eli Lilly’s oral weight‑loss medication, orforglipron—marketed under the brand name Foundayo. This makes Foundayo the second GLP‑1 pill to reach U.S. consumers, following Novo Nordisk’s Wegovy tablet approved in December. Orforglipron works by mimicking a natural hormone that regulates appetite and satiety, offering a non‑injectable alternative to existing GLP‑1 injectables. David A. Ricks, Eli Lilly’s chair and CEO, highlighted that fewer than one in ten eligible patients are currently using GLP‑1 therapies, citing barriers such as cost, stigma, and perceived complexity. Unlike Wegovy, which must be taken on an empty stomach each morning, Foundayo can be taken anytime of day regardless of meals, simplifying dosing schedules. Patients will start on a low dose that is gradually increased to mitigate side‑effects. Pricing is projected at $149 per month for the initial dose, with higher‑strength formulations potentially reaching $349 monthly. While private‑insurance coverage remains uncertain, a Trump‑administration proposal could allow Medicare to cover certain patients as early as this summer, with copayments as low as $50 per month. Distribution will commence on Monday through LillyDirect’s direct‑to‑consumer channel, with broader availability in pharmacies and telehealth platforms expected shortly thereafter. The convenience of a once‑daily pill is anticipated to improve adherence, especially for individuals who avoid injectables due to needle aversion or rigid dosing requirements. The approval follows a fast‑track submission submitted only months ago, positioning Foundayo to enter the market roughly three months after Wegovy. This rapid rollout is set to intensify competition in the burgeoning GLP‑1 space, where new agents are continually emerging with claims of better efficacy and lower costs.

Cooper Lutkenhaus, a 17-year-old American high school student, has taken the athletics world by storm by becoming the youngest world champion in track and field history. He achieved this incredible feat by winning the 800m indoor world championship in Torun, Poland.Lutkenhaus's remarkable talent has drawn comparisons to top athletes like David Rudisha, with Belgian athlete Eliott Crestan saying, 'He's like David Rudisha... In 10 or 20 years' time, I'll be able to say that I ran against him.'The young athlete's coach, Chris Capeau, attributes his success to a combination of 'God's gifts, his mum and dad's genetics, and his upbringing.' Capeau also highlights Lutkenhaus's intense focus on detail and his ruthless approach to maximizing his potential.Lutkenhaus's achievements have made him a sensation in the athletics world, with many eagerly anticipating his future performances, including his participation in the Eugene and Stockholm Diamond League this summer.Despite his remarkable success, Lutkenhaus remains humble and grounded, celebrating his gold medal with a simple burger and fries with his family. His father, George, emphasizes the importance of allowing his son to enjoy the moment and not getting caught up in the hype surrounding his achievements.