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The Rediscovery of a Forgotten VisionaryGordon Stevenson, a multifaceted artist who made significant contributions to New York's late-70s no wave scene, is about to experience a posthumous renaissance. Four decades after his death, Stevenson has been largely remembered as merely a footnote in other people's stories. However, this is about to change dramatically with the discovery of a storage unit filled with his lost work, including jewelry, collaborations with mail-art pioneer Ray Johnson, and even clues to the whereabouts of a surviving print of his notorious film, Ecstatic Stigmatic.The Early Life and InfluencesStevenson's story begins not in the gritty streets of New York, but 900 miles south in the small town of Dublin, Georgia. Born into a family of "emotionally repressed stoics," he was a maths prodigy with a taste for Flannery O'Connor, Nietzsche, and Sartre. His intellectual pursuits and unconventional lifestyle created a rift with his parents, who expected him to follow a more traditional path. Offered a maths scholarship at Georgia Tech, Stevenson instead chose the liberal arts campus of Eckerd College in St. Petersburg, Florida, further widening the divide with his family.The New York YearsIn 1977, Stevenson and his partner Mirielle Cervenka relocated to New York, a city that photographer Julia Gorton described as "a nihilistic playground for people with trauma." The city was "very destroyed by the drugs and violence," according to Maripol, a European émigré designer and filmmaker who later worked with Grace Jones and Madonna. "But there was freedom. That the city was bankrupt meant low rents. Creative people could afford to live there," Maripol recalls.The Artistic LegacyStevenson's artistic contributions were multifaceted. He and Cervenka founded the jewelry brand LHOOQ, which "repositioned the jewellery for the punk market" by upcycling vintage trinkets. His "memento mori" series focused on crosses and skulls, anticipating gothic fashion and showcasing a macabre sensibility. In music, he joined Lydia Lunch's Teenage Jesus and the Jerks, a band that was, according to Gorton, "really intense, abrasive, not friendly – just a perfect band." Jim Sclavunos, who later drummed for Sonic Youth and Nick Cave and the Bad Seeds, remembers Stevenson as "a very striking presence, depraved in the right ways." His most ambitious work was the film Ecstatic Stigmatic, a $5,000 production inspired by Catholic mysticism and the Jonestown massacre, which Sclavunos found "surprised by how good it was. A lot of no wave cinema looked juvenile. But Ecstatic Stigmatic was very shadowy, sleazy and sexual."The Impact on Contemporary CultureThe rediscovery of Stevenson's work comes at a time when there is renewed interest in the no wave movement and its influence on contemporary art and music. His story offers insight into the creative ferment of late-70s New York, a time when the city's financial struggles paradoxically created space for artistic experimentation. The letters Stevenson wrote to his parents, which his family has recovered, provide a personal window into this period, chronicling life in the downtown demimonde and his experiences as one of New York's first Aids patients. As his sister Barbara Stevenson notes, "Gordon always belonged in New York," and with this rediscovery, his rightful place in the city's artistic pantheon is finally being secured.

The Philippine government has formally committed to surrendering fugitive Senator Ronald "Bato" dela Rosa to the International Criminal Court (ICC) following a dramatic confrontation at the Senate building that ended in gunfire and his escape.Senate Standoff and ICC Warrant UnsealedJustice Secretary Fredderick Vida confirmed on Friday that Manila has received the ICC’s arrest warrant for Senator Ronald dela Rosa, 64, and considers it valid. The former national police chief, instrumental in President Rodrigo Duterte's drug war, fortified himself in the Senate building after law enforcement agents attempted to arrest him on Monday.The situation escalated rapidly, with more than a dozen gunshots ringing out as armed soldiers charged the legislative building two days later. Although it remains unclear who fired the shots, the Senate president confirmed by Thursday that dela Rosa was no longer inside the building. With his whereabouts unknown, authorities have warned that any attempt to help him flee the country would be treated as a "mockery of justice."The Scale of the Alleged CrimesDela Rosa faces charges of crimes against humanity, similar to those against Duterte, who has been held in ICC custody in The Hague since March 2025. The former police chief is named as one of eight co-perpetrators in the case and is accused of serving as Duterte's top enforcer.The ICC estimates that the former president's "war on drugs" campaign, which ran from 2016 to 2019, resulted in the deaths of between 12,000 and 30,000 people through extrajudicial killings.A Test of Judicial SovereigntyThis incident marks a significant test of the Philippines' relationship with international justice. While Vida stated that the government will "definitely submit" to the ICC's request, the process is contingent on the Philippine Supreme Court resolving the senator's petition against the warrant's legality.The standoff highlights the deep political divisions within the nation, as dela Rosa attempted to cast a deciding vote in a leadership contest that would have handed power to a Duterte ally. His disappearance has effectively paralyzed a key legislative vote, raising questions about the stability of the current administration.The Path to ExtraditionIn an interview aired on Thursday, dela Rosa pledged to "exhaust all available remedies" to block his transfer to the ICC. The immediate future now hinges on the Supreme Court's ruling. If the court rules against the warrant, dela Rosa may remain free; however, if the court upholds the ICC's authority, extradition proceedings are likely to begin immediately, bringing a controversial chapter of Philippine history to a head.

Senator Dela Rosa Leaves Senate After ICC Arrest ThreatOn May 14, 2026, Senate President Alan Peter Cayetano confirmed that the former police chief and senator was no longer inside the Senate building, where he had been taking refuge from a pending ICC arrest warrant.Senator Ronald “Bato” dela Rosa had been under Senate protection since the ICC announced a warrant for his alleged crimes against humanity.The sergeant‑at‑arms reported his departure early Thursday morning. Escalation Inside the Senate: Gunfire, Police Presence, and the Senator’s ExitWednesday’s chaos included:Gunshots that rang out inside the chamber, prompting lawmakers to scramble for cover.A heavy police and Marine presence, with armed guards stationed around the Senate.Protests outside the building and a reported arrest of one individual linked to the shooting. Human‑Rights Toll: ICC’s Estimate of 12,000‑30,000 Deaths in Duterte’s Drug WarThe ICC’s unsealed warrant cites the same crimes against humanity alleged against former President Rodrigo Duterte. The court estimates that between 12,000‑30,000 people were killed during the 2016‑2019 “war on drugs.” Political Fallout: Strain on Philippine Institutions and International ScrutinyThe incident underscores growing tension between the Philippine government and international judicial bodies:President Ferdinand Marcos Jr convened an emergency meeting with security chiefs to manage the crisis.Lawyer Jimmy Bondoc maintains that Dela Rosa had no plans to leave, highlighting a disconnect between legal counsel and on‑ground realities.Public confidence in Senate security protocols is being questioned amid the chaotic episode. What Lies Ahead: Legal Battles, Possible Extradition, and Domestic UnrestLooking forward, several scenarios could shape the next weeks:Dela Rosa may seek to “exhaust all available remedies” to block his transfer to The Hague.The Philippine government could face diplomatic pressure to cooperate with the ICC or risk further isolation.Continued protests and potential security incidents may arise if the senator’s legal status remains unresolved.

The Senate StandoffMore than a dozen gunshots rang out at the Philippine Senate as police and marines moved in to arrest a senator wanted by the International Criminal Court for alleged crimes against humanity. Journalists ran for cover as gunfire erupted on Wednesday evening minutes after soldiers with rifles and protective gear went up the stairs of the legislative building. It was not immediately clear who fired the shots during the tense confrontation.Arrest Warrant and Senator's DefiancePhilippine Senator Ronald dela Rosa had earlier anticipated his arrest, urging people to come to the legislature to prevent him from being detained and sent to the ICC. "I am appealing to you. I hope you can help me. Do not allow another Filipino to be brought to The Hague," dela Rosa said in a video posted on Facebook. Philippine law enforcement agents had been gathering outside the Senate building after dela Rosa's message.The ICC Charges and Drug War LegacyThe ICC unsealed an arrest warrant on Monday for dela Rosa, dated November, on suspicion of crimes against humanity, the same crimes 81-year-old Duterte is accused of as he awaits trial in The Hague. Dela Rosa, better known as "Bato", meaning "rock", has been under the protective custody of the Senate since law enforcement agents entered the building on Monday. He has denied involvement in illegal killings, stating "I did everything for the country. I did not enrich myself. I worked faithfully."Political Implications for the Marcos AdministrationFormer police chief dela Rosa, who was the top enforcer of ex-President Rodrigo Duterte's so-called "war on drugs", urged President Ferdinand Marcos Jr on Tuesday not to hand him over to the ICC, adding that he was ready to face justice at home. "Mr President, [you] may one day face a situation like this. You may also encounter problems, and then you will understand, you will feel what I am feeling right now," dela Rosa told reporters, his eyes welling with tears. The incident places the current administration in a difficult position balancing international legal obligations with domestic political considerations.Future Legal ProceedingsDela Rosa was Duterte's top lieutenant and oversaw a fierce crackdown during which police say more than 6,000 suspected drug dealers were killed in official operations. Thousands of drug users were also shot in slumland murders blamed on vigilantes or turf wars. Police say those killed during operations had resisted arrest and reject allegations of systematic murders and cover-ups. As the ICC case progresses, the Philippines faces continued scrutiny over human rights issues and the legacy of the drug war that defined Duterte's presidency and continues to influence the nation's political landscape.

The Lead: Carla Simón's Unique Approach to Family DramaFamily reunions in European arthouse cinema are almost always unhappy events, on a scale of strife that ranges from simmering resentment to spectacular score-settling. Carla Simón, however, has a rare gift: she makes you leave the cinema with renewed faith that having relatives and keeping in touch with them may actually be a wonderful thing.No film-maker working in Europe now is as capable of turning birthday gatherings, garden parties or poolside barbecues into thrillingly sprawling canvases of human virtue and vice as this 39-year-old rising star. From a riotous water fight in the Berlinale Golden Bear-winning farming drama Alcarràs to a foul-mouthed dinner table singalong in her new film Romería, Simón directs kinship meetings with the attention to detail that other film-makers may invest in action sequences or dance routines.The Event Details: Romería and the Journey to Self-DiscoveryAmong the tricks Simón employs, she explains, is to ensure her actors only read the script once before the camera starts rolling, so they have to improvise to fill the gaps. She takes her casts to parties, for walks and on shopping trips, and if there are disagreements on the way, so much the better. The ultimate secret sauce, though, is to ignore WC Fields's notorious advice and always work with children and animals."I never get bored of working with kids," she says. "When you are only working with adult actors, shooting becomes more like executing an idea that you have in your mind, and I think that is not interesting. With children, you always have this feeling that that things are going to happen in front of the camera by chance. It keeps things alive."Her new film Romería, meaning "pilgrimage" in Spanish, dives deeper into the story of the biological parents she barely got to know. Eighteen-year-old Marina travels to her relatives in Vigo, in north-western Galicia, purportedly to find the death certificate of her biological father, which she needs to study film-making in Barcelona. The initial reaction is warm, but family is a room with dark corners and locked closets.The Personal Journey: Aids, Loss and Family SecretsSimón's fascination with freewheeling scenes of family life was undoubtedly honed through her own biography. Born in Barcelona in 1986, her father died when she was three and her mother when she was six. Both of them succumbed to Aids. She was 12 when her adoptive mother told her that her parents had been infected with the autoimmune disease through their use of drugs.All of her first three films have been strongly autobiographical: Summer 1993 tells the story of a six-year-old girl who moves to an unspecified location countryside to live with her aunt after the death of her mother, while 2022's Alcarràs is specifically set in the Catalan peach-growing community of her adoptive family.In the film, a cache of letters written by her late mother opens up a portal to the time when her parents met and discovered love – for each other, the Atlantic Ocean and drugs. The letters, Simón explains, are real. "She wrote to her friends and family while she lived in Vigo. Her Catalan is full of mistakes, because teaching Catalan was banned under the Franco regime. But they are the most important thing that I have from my mother, because suddenly I can hear her talking."The Impact Analysis: Spanish Cinema and the Legacy of AidsSpanish cinema has a track record in making films where child actors take centre stage: Ana Torrent's spell-binding turn as a young girl obsessed with the Frankenstein tale in Víctor Erice's 1973 film The Spirit of the Beehive is considered an all-time great performance by a minor, and Simón describes it as "a very, very important film for me".During the transition period after Franco's rule, Madrid gave birth to la movida, a countercultural movement that celebrated lifestyles that had been banned under military rule. "All these kids who were raised under Franco and religious oppression, suddenly freedom arrived and they embraced it", Simón says. "They didn't think much about the future or the consequences of what they were experimenting with. And then the drugs came in."When we talk about this generation in Spain, people sometimes use words like shame and blame, but I feel that's really unfair: people like my parents just had bad luck.The Future Direction: Beyond Family in Simón's Next ProjectHalfway through Romería there is a stylistic shift, from the Eurorealism she favoured in her previous works toward something more magical-realist: there is a mysterious cat you might expect to encounter in a Miyazaki film, and an unforgettable dance number set to Vigo punk rocker's Siniestro Total's song Bailaré Sobre Tu Tumba ("I'll Dance on Your Grave")."These three films I've made are kind of a cycle, because they all talk about my family, adoptive and biological. But since I became a mother a few years ago, I feel that my place in the family changed. When you have kids you feel it's a new period in your life, so I feel like maybe doing something that has nothing to do with my family."Her next film, she confides, is going to be a flamenco musical.

The Cultural Phenomenon Returns On a chilly morning at a Silvertown studio behind London City airport, the sunburst intro to Jimmy Cliff's The Harder They Come is on repeat. Dancers run through a routine studded with reggae and dancehall moves. "Get high," commands associate choreographer Neisha-yen Jones with a smile. "Get low!" The ensemble rise and dip. They do the bogle and whine around each other as their watchful director Matthew Xia nods along. They circle Natey Jones who breaks out the opening line: "Well, they tell me of a pie up in the sky." In the distance, a plane leaves the ground. From Film to Theatrical Celebration It's eight months since The Harder They Come's full-throttle takeoff at Stratford East, where the musical was so popular that it is now returning for a second run which will also serve as a eulogy for Cliff who died in November. Playwright Suzan-Lori Parks' adaptation of Perry Henzell's 1972 Jamaican film is bolstered by a handful of her own songs as well as classics including Israelites and Wonderful World, Beautiful People – plus every number on the film's monumental soundtrack. Jones is reprising the role of Ivan (played on screen by Cliff and inspired by real-life outlaw Rhyging), who arrives in Kingston from the country and is dismissed and exploited, before becoming both a hit singer and a fugitive. The Evolution of a Cultural Narrative The original was akin to cinéma vérité, directly evoked spaghetti westerns and veered into blaxploitation territory; Ivan's tale has gained greater warmth, humour and protest spirit on stage. It was the best musical I saw in 2025. "The story is a tragedy but the theatrical event is a celebration," says Xia of his production. Twenty years ago, the film was adapted as a musical with a book by Henzell, also at Stratford East. "It all started at Ivan's Nine Night," Xia recalls. "There was a massive poster of Ivan on the wall, with everyone coming, and it was told in retrospect with vignettes." Choreography and Cultural Connection Shelley Maxwell, recently arrived from Jamaica, was watching the musical in the audience one night and has since become the choreographer of the new production. She has fused the folk dance forms of revivalism and pocomania, learned in her childhood, with reggae, dancehall and moves that today's teenagers can recognise. "I wanted to tap into the youth market," she says. It's brought some enthusiastic feedback from audience members who may not know the film. "Like: 'Oh my God, they did that step I always do at a party!' It allows them to form a connection." Authenticity and Cultural Representation Xia, wearing trainers in the Jamaican flag's colours, and Maxwell, whose tracksuit has the same black, green and gold trim, were intent on instantly transporting their audience to Kingston. The opening, says the director, is an "establishing shot" with characters coming and going on Simon Kenny's magnificent multi-level set, accompanied by Toots and the Maytals' hit Funky Kingston. To borrow from its lyrics, you really can believe everything they do. Even each move in the dominoes game we see is scripted, explains Maxwell, who mapped out the market scene with precision: "Where are you going to? How heavy is the item that you're holding? This is the swing of the hips." Social Commentary Through Performance Xia, whose father came to England from Jamaica in the 1970s, praises the freewheeling realism of the film. "Lots of the background performers are just whoever happened to be in the market that day, or walking through the shantytown. Lots of the actors were people that Perry knew, they had no training." Henzell, says Xia, showed "the part of Jamaica that had always been hidden, people living hand to mouth". The musical depicts a "quartet of oppression" against Ivan, as he takes a stand against individuals representing hypocrisies of the church, law, drugs trade and music industry. Universal Themes and Contemporary Relevance The Harder They Come was both a pioneering example of independent film-making for Jamaicans and a portrait of a newly independent country. Maxwell, who grew up glued to Hollywood musicals, says it was empowering to discover a film full of the Jamaican songs she loved. "I was probably way too young when I saw it. But what I saw was the world around me." She traces how different forms of music played a pivotal part in the country establishing its identity, moving from African forms and American R&B; to mento, ska, rocksteady, reggae and the rise of Bob Marley and Jimmy Cliff. Maxwell captures that chain reaction with a tantalizing question: "What's this groove becoming?" Transforming the Narrative for Modern Audiences The musical also makes its hero's actions more understandable. "In the film, Ivan becomes a kind of wanton murderer," says Xia. In the musical, "he accidentally shoots a police officer when he's under threat, is remorseful, yet also knows that if he gives himself in then that's the end of his journey". Another significant change is the depth given to the principal women – Ivan's mother Daisy and Elsa, with whom he falls in love under the eye of her authoritarian guardian, the preacher. "The moral heart of the piece now resides in those two women," says Xia. Maxwell transforms a brief sequence from the film, in which Ivan imagines a tryst with the devout Elsa, into a floor-trembling set piece when the preacher's congregation lose their robes to indulge in lustful fantasy. The male gaze of the original scene is duly excised: "it had to be like it was both of them in partnership in that fantasy world," says Maxwell, who adds that the nature of dancehall – "grinding, gyrating on another body" required her to use her skillset as an intimacy director.

A new large‑scale randomized trial presented at the European Congress on Obesity in Istanbul indicates that the oral GLP‑1 antagonist orforglipron can help patients retain the majority of weight lost with injectable therapies such as tirzepatide (Mounjaro) and semaglutide (Wegovy).Trial Shows Oral Orforglipron Preserves Most Weight After Switching from InjectablesThe study, funded by Eli Lilly, followed 376 US patients who had been on tirzepatide or semaglutide injections for 72 weeks and then randomized them to a daily orforglipron tablet or placebo for an additional year.Participants were previously on weekly GLP‑1 jabs that typically produce 15‑20% body‑weight loss.After the injection phase, subjects were switched to oral therapy or placebo for 12 months.Primary endpoint: proportion of weight loss retained at 12 months.Quantitative Outcomes: 75% vs 49% Retention for Tirzepatide Users, 80% vs 38% for Semaglutide UsersWeight‑loss maintenance differed markedly between the pill and placebo groups:Tirzepatide cohort: 75% of lost weight retained with orforglipron vs 49% with placebo.Semaglutide cohort: 80% retained with the pill vs 38% with placebo.Secondary benefits—blood pressure, cholesterol, and glycaemic control—were also sustained in the pill arm.Implications for Obesity Management and Healthcare CostsExperts highlighted the broader significance:Dr Louis Aronne (Weill Cornell Medicine) emphasized that treating obesity directly can simultaneously improve glucose, lipid, and blood‑pressure metrics.Dr Marie Spreckley (University of Cambridge) noted patient preference for oral therapy due to convenience, storage, and lower cost.Dr Simon Cork (Anglia Ruskin University) warned that injectable GLP‑1 drugs, while highly effective, are expensive and limit long‑term accessibility for both private payers and the NHS.The findings suggest a potential shift toward oral agents that maintain efficacy while reducing financial and logistical burdens.Future Outlook: Oral GLP‑1 Therapies Could Redefine Chronic Obesity CareIf further trials confirm these results, orforglipron could become a cornerstone of chronic obesity management, enabling earlier intervention (BMI 25‑27) and possibly preventing progression to severe obesity.Regulators and payers will likely scrutinize cost‑effectiveness models, but the prospect of a cheap, daily tablet that sustains weight loss may reshape treatment algorithms worldwide.

The Trump-Xi Summit: A Pivotal Moment in US-China Relations Donald Trump's state visit to China this week – the first by the US president in nearly a decade – comes amid a time of geopolitical upheaval, a new and intractable conflict in the Middle East, and a sometimes rocky relationship between the world's two major superpowers. There is much for Trump and Xi Jinping to discuss, but a few key issues are likely to dominate the agenda. Five Critical Issues on the Summit Agenda The high-stakes meeting between the two leaders addresses several pressing matters that could reshape the global landscape: The Iran Conflict and Hormuz Strait Crisis Trump is eager for China to lean on Tehran to advance peace talks and reopen the strait of Hormuz. To now, Beijing has sat back and watched the US struggle against Iran, at least publicly. But with about half of China's crude oil imports passing through the strait, Xi does want the waterway unblocked. China knows its exports will suffer if a global recession results from an oil supply crisis. Complicating the picture, the US this week put sanctions on several Chinese firms accused of assisting Iranian oil shipments and supplying satellite imagery allegedly used in Iranian military operations, claims that Beijing denied. Trump's arrival comes after Iran's foreign minister, Abbas Araghchi, visited Beijing last week. Taiwan: The Flashpoint in US-China Relations Beijing is keen to push the US on Taiwan, with Trump saying he is prepared to raise the issue of arms sales to the island, which China claims as a breakaway territory despite never having ruled it. In December, Trump authorised an $11bn arms package for Taiwan, the largest weapons sale ever to the island, but no shipments have been made yet. Xi may seek changes in how the US refers to Taiwan. Ideally, from the perspective of Beijing, this would be a statement from Washington "opposing" Taiwan's independence rather than "not supporting" it. Taiwan will be watching closely. Just two weeks ago, China's foreign minister in a phone call with Marco Rubio urged the US to "make the right choices" on Taiwan. With Trump known to veer off script, John Kirby, a former US state department and Pentagon spokesperson cautioned: "They just have to be so extraordinarily precise when you're talking about Taiwan because, quite frankly, the stakes are enormously high." The AI Cold War: Technological Supremacy at Stake China and the US are locked into a race on artificial intelligence that is becoming something of a technological cold war. In April, the White House accused China of stealing US AI labs' intellectual property on an industrial scale, claims Beijing denied. Meanwhile, Beijing has been frustrated by Washington's reluctance to allow Nvidia to export its most powerful processing chips to China. In January, the White House said Nvidia could export its second most powerful chip, the H200, but no shipments have been sent yet. Analysts and ethics leaders hope Trump and Xi will discuss non-binding AI guidelines, including sharing information about AI misuse and safety, which are seen as critical guardrails amid the advent of AI weaponry and military adoption. Trade War: Rare Earth Minerals and Economic Leverage Trump has repeatedly threatened China over trade, imposing tariffs above 140% last year. But Xi held some cards of his own and did not fold. Instead, China blocked exports of its rare earth minerals and magnets to the US. Trump, finally, backed down. The US has depleted notable levels of its weapons arsenal in the war against Iran, with many weaponry components requiring critical minerals that are linked to supply chains dominated by China. China is expected to announce purchases related to Boeing airplanes, American agriculture and energy, US officials have said. In turn, Beijing wants the US to ease curbs on exports of advanced semiconductors. Beijing also wants to reduce barriers to investment in the US, and hopes to establish a Board of Investment to match the Trump-back Board of Trade. Fentanyl: The Drug War and Political Posturing Fentanyl is a key item on Trump's agenda this week, Politico reported, citing an administration official granted anonymity to preview the closed-door sessions. The US has long accused Chinese businesses of knowingly supplying the chemical precursors to Mexican cartels who use them to make the drug. Trump knows that being seen to press China hard over fentanyl and precursors plays well with his Maga base. But Trump lost important leverage on the fentanyl front when China defied his tariffs threats. In March, the US and China clashed over fentanyl and trade at a UN drugs meeting. China wants to be removed from the state department's annual list of "major drug transit or illicit drug producing countries", due to be updated in September.

The LeadRobert Smith, a distinguished pharmacologist and professor at St Mary's medical school in London (now part of Imperial College), has died aged 92. His groundbreaking work on how genetic variations affect drug responses helped shape the field of personalized medicine.The Discovery of Debrisoquine PolymorphismBob became well known for his role in the discovery of "debrisoquine polymorphism." In 1975, as one of five volunteer researchers who took debrisoquine, a blood pressure medication, he was the only one to suffer adverse effects (hypotension) and collapse. This led to the discovery of a genetic polymorphism where certain individuals cannot break down specific drugs efficiently. While Bob described this as an "accident waiting to happen," it positioned him at the forefront of pharmacogenetics.Awards and RecognitionSmith's contributions to pharmacology were formally recognized when he became the first recipient of the Paton prize in 1998 for his work in understanding how genes affect drug response. His academic achievements included becoming professor of pharmacology in 1978 and serving as deputy dean of the medical school from 1980-88.Impact on Medicine and SportsSmith's research fundamentally changed how medical professionals understand drug responses, paving the way for personalized medicine approaches. Beyond human medicine, he applied these principles to horse racing, chairing the UK Horserace Scientific Advisory Committee (1979-99) and its pan-European equivalent (1992-2005). He also served as a director of the Horseracing Forensic Laboratory in Newmarket during the 1990s, helping shape anti-doping protocols.Enduring LegacySmith never fully retired, continuing his research as emeritus professor until publishing his last paper in 2020. His legacy extends beyond scientific contributions to include the principles, warmth, kindness and generosity he embodied throughout his career. His work continues to influence pharmacology and personalized medicine, ensuring his impact will be felt for generations to come.