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The Familiar FinalYou could be forgiven for having a sense of deja vu before a fourth Champions League final between the Spanish champions, Barcelona, and French champions, Lyonnes, on Saturday evening.The three-time champions and eight-time champions played each other in the final of Europe's premier competition three times in six years between 2019 and 2024, with Lyonnes earning a 4-1 win over the Catalan giants in 2019 and a 3-1 win in 2022 before Barcelona delivered a 2-0 defeat of the French side in 2024.However, predicting the outcome could not be harder and Barcelona's talismanic No 11, Alexia Putellas, said there is little that can be discerned from those previous meetings. "We can't compare seasons and we can't compare finals," said the two-time Ballon d'Or winner. "Our squad has evolved a lot, so previous finals don't have an influence on the final we are playing tomorrow."The Tactical Chess MatchA lot has changed. Most notably, Lyonnes are now managed by Jonatan Giráldez, who was a coach at Barcelona as they claimed their maiden UWCL title and at the helm for their second and third. Few managers are better equipped to return Lyonnes to the top of European football after a three-year hiatus than the man who understands the way Barça work and exactly how they ended the domination of the French side.As a result, the tactical approach of those on the sidelines is perhaps the most interesting piece of the puzzle in Oslo's Ullevaal Stadion.Giráldez said of Barça's development since he left: "They have some different players but their identity remains the same; this will to dominate and apply pressure. Not thinking about the result as much as about the show and the performance, that's their identity. I feel privileged to face Barcelona as I'm grateful for the experience I had there and I wish them the best – except when we have to win!"Master and ApprenticeOne of Giráldez's two assistants, Pere Romeu, replaced him when he departed for Washington Spirit in June 2024. "We are the two teams that have done the most in this competition to reach the final in recent years," said Romeu. "Tomorrow is going to be a very demanding match. Tomorrow is going to be a match with a lot of quality from both teams. Tomorrow is going to be a match that, as in all finals, is going to be decided by small details. We are going to try to take care of and control it to the maximum."The 32-year-old Barcelona manager won a domestic treble in his first season in charge, but fell short in the Champions League final last season as Arsenal delivered a shock defeat."I see a team that is more mature than last season," said Romeu. "I see a team with greater capacity to change things during the game than last season and I think we have reached a good point."Putellas described Romeu as a "complete coach", before the showdown on Saturday. "We've been working together for several seasons now and he has always tried to help me evolve as a player, which I'm very grateful for," she said. "He's the most complete coach. This season I've tried to do the best I possibly can without forgetting my own qualities in order to help the team."Romeu is relishing the master-apprentice battle in such a significant game. "I, as a coach, am super-excited to be able to face this match against a former coach of the club in Jonatan," he said. "I'm sure we'll both do everything we can to keep our teams' identities and keep doing the best we can to win."Dominate DomesticallyBarcelona secured another domestic treble on Saturday with a 3-1 Copa de la Reina final win over Atlético Madrid in their final game before travelling to Norway. Meanwhile, Lyonnes are one game away from their own domestic treble, having dispatched Nantes with an emphatic 8-0 win in the semi-final of the Premiere Ligue play-offs, with the final between the holders and Paris FC, taking place next Friday.The Lyonnes midfielder Lily Yohannes told Uefa that the club "just have so much hunger in us," after their three-year European dry spell. "We have so much fight. No matter what happens, we stick together, we rise above the challenges, and we just have such a winning mentality in the group."The 35-year-old centre-back Wendie Renard, who has been involved in each of the club's record eight Champions League wins, similarly spoke about a togetherness and desire in the team after a disappointing European run last season."If I had to sum up our journey this season: dedication," she told Uefa. "A Champions League campaign never comes easy, from one game to another. We've also had doubts and fears at times, but the squad has remained strong, and we've kept focusing on work and humility and performed well together."The Midfield BattleThe midfield battle will be key, with the impact of Melchie Dumornay, who was the difference maker in their semi-final fightback against Arsenal, critical for Lyonnes and Barcelona unsure of the readiness of the three-time Ballon d'Or winner Aitana Bonmatí, who is "feeling better every day", according to Romeu, but has not played 90 minutes for the team since November and only played 18 minutes of the Copa de la Reina final.Contrasting StylesThe Champions League final will ultimately be a contest between two different ways of playing, Barcelona's slick tiki-taka football and the more aggressive way Lyonnes play. Both cannot dominate possession in this game, one will have to cede it and find a different way to win. That is what makes it an enthralling fixture.

The Humanitarian Crisis in Lebanon A heart-wrenching story has emerged from Lebanon, where a displaced amputee is desperately seeking help. The individual, who has been forced to flee their home, is now facing an uncertain future. The Struggle for Displacement The amputee's question, 'where am I supposed to go?' echoes the sentiments of many displaced people in the region. Lebanon has been grappling with a severe refugee crisis, with many individuals forced to flee their homes due to conflict, poverty, or persecution. The Need for Support The situation highlights the urgent need for support and assistance for displaced people in Lebanon. The international community must come together to provide aid and shelter to those in need. A Call to Action As the situation continues to unfold, it is essential that we raise awareness about the plight of displaced people in Lebanon. By sharing stories like this, we can help bring attention to the issue and inspire action to support those in need.

The Lead: Pakistan's Diplomatic Push in Iran CrisisPakistan's army chief, Field Marshal Asim Munir, is in Iran as part of ongoing mediation efforts to end the Israel and United States's war that began on February 28. This high-level diplomatic visit comes as the US reports slight progress in negotiations while tensions remain high in the region.The Event Details: Pakistan's Second Mediation MissionMunir arrived in Tehran on Friday, Iran's state-run IRNA news agency reported, citing the Pakistan Army. "On arrival, he was received and warmly welcomed by Iranian Interior Minister Eskandar Momeni," IRNA said, adding that "Pakistan's Interior Minister Mohsin Naqvi was also present at the reception."It is the second such trip to Tehran by Munir amid Pakistani mediation efforts to end the war. Islamabad helped secure a temporary ceasefire between the warring sides on April 8, and later hosted the highest-level talks between the US and Iran since 1979 on April 11-12.During this visit to Iran, unnamed Pakistani sources told the Anadolu news agency that Munir will discuss Iran-US talks, regional peace and stability, and other "important issues".The Data Analysis: Shifting Positions in Negotiations"The current process and the presence of senior Pakistani officials in Tehran means that we have reached a turning point or a decisive situation," Iran's Foreign Ministry spokesperson Esmaeil ⁠Baghaei said on Friday.Iranian state media quoted Baghaei as saying the gaps between Tehran and Washington are "deep and significant". "We cannot necessarily say that we have reached a point where an agreement is close," he said. "The focus of the negotiations is on ending the war. Details related to the nuclear issue are not being discussed at this stage."Speaking at the White House on Friday, US President Donald Trump said, "Iran is dying to make a deal". "We'll see what happens. But we hit them hard, and we had no choice because Iran cannot have a nuclear weapon. They cannot have it," Trump added.US Secretary of State Marco Rubio said on Friday that "slight progress" was made during talks with Iran. "I don't want to exaggerate the progress in talks, saying there had been 'a little bit of movement, and that's good'. He said the conversations were ongoing.The Impact Analysis: Regional and Global RamificationsThe Iran war and the closure of the Strait of Hormuz, which normally carries a fifth of global oil production, have sent ripples through the global economy, driving energy prices soaring.As diplomatic efforts continue, European Union nations moved towards imposing sanctions on Iranian officials and others responsible for blocking the Strait of Hormuz, the EU said on Friday. Tehran effectively closed the key shipping lane for global oil and gas supplies in retaliation for the US-Israeli war."The EU will now be able to introduce further restrictive measures in response to Iran's actions undermining the freedom of navigation in the Strait of Hormuz," the European Council representing EU nations said.Trump has repeatedly set deadlines for Tehran and then backed off. But he's also previously indicated he would hold off on military action to allow talks to continue, only to turn around and launch strikes. The US president said he called off attacks on Iran this week at the request of allies in the Middle East, including the leaders of Qatar, Saudi Arabia and the United Arab Emirates.The Prediction: Path Forward for Diplomatic SolutionsIran's ⁠Baghaei said ⁠on Friday that a Qatari delegation ‌was currently holding talks with Iran's foreign minister, ⁠but added that ⁠Pakistan remained the main ⁠mediator in ⁠the ⁠negotiations.With Pakistan intensifying its mediation process to secure a second round of direct talks between the US and Iran, the region remains on edge. While both sides report some progress, the deep gaps between Tehran and Washington suggest that a comprehensive resolution to the conflict remains elusive, with potential for both diplomatic breakthroughs and military escalation still on the table.

The Lead: Guardiola's Legacy Beyond FootballPep Guardiola is more than a football manager, using his high-profile platform to highlight causes close to his heart. As he prepares to step away from Manchester City after 10 years and 20 trophies, the 55-year-old Spaniard leaves behind a legacy of advocacy that extends far beyond the "beautiful game."The Event Details: A Manager's Platform for Social ChangeLegendary Liverpool manager Bill Shankly may have believed football was "much, much more important" than life or death, but for Guardiola, several things outside football matter almost as much. From Palestinian children to Catalan independence and homelessness in the United Kingdom, Guardiola has strayed outside the borders of his job to advocate for a diverse range of causes during his managerial career.Guardiola has made no bones about using his position as a podium to "speak up to be a better society." His most recent foray into sensitive political territory has been his passionate embrace of the predicament of Palestinian children in Gaza during the two-year war with Israel and their suffering in the aftermath.The Data Analysis: Impact and ControversyThe war in Gaza, which began after Hamas's October 2023 attack on Israel, has killed at least 72,568 people, including children from toddlers to late teens. Hundreds of thousands of displaced people still live in tents, with conditions remaining dire despite a ceasefire that came into effect in October.Guardiola's advocacy has not been without controversy. His remarks about Palestine prompted the Jewish Representative Council of Greater Manchester and Region to write a letter to Manchester City chairman Khaldoon Al Mubarak, warning his comments put the lives of Jews in Manchester "in danger." Similarly, he was fined £20,000 ($27,000) by the Football Association in 2018 for wearing a yellow ribbon to support imprisoned politicians in his native Catalonia.The Impact Analysis: Shaping Public DiscourseWhile Guardiola's advocacy has met with criticism from some quarters, it has also sparked important conversations about global issues. His willingness to speak out on sensitive topics has demonstrated how athletes and sports figures can use their platforms to draw attention to humanitarian crises and social justice issues.Guardiola's influence extends beyond his immediate audience. When he missed a pre-match news conference to attend a charity event for Palestinian children in Barcelona, his actions garnered international attention. Similarly, his support for the Salvation Army's Partnership Trophy, a five-a-side football tournament in Manchester that raises awareness of homelessness, has helped shine a light on this often-overlooked issue.The Prediction: The Future of Athlete AdvocacyAs Guardiola transitions from his managerial role, his legacy of advocacy may inspire other sports figures to follow suit. In an era where athletes are increasingly using their platforms for social and political causes, Guardiola's approach—unapologetic, consistent, and multifaceted—could become a model for how sports figures can leverage their influence for meaningful change.His willingness to address complex geopolitical issues, from the Middle East to Ukraine and Sudan, suggests that future athlete advocates may become more engaged with global affairs, recognizing their potential to shape public discourse and bring attention to underserved communities and causes.

The Strategic Reversal in Immigration Policy The Trump administration has officially shifted the procedural landscape for permanent residency, instructing foreign nationals currently in the US on temporary visas to return to their home countries to apply for Green Cards. This directive, issued by the Department of Homeland Security (DHS) and US Citizenship and Immigration Services (USCIS), frames the policy as a necessary correction to the existing legal system. By emphasizing that "adjustment of status" is a discretionary benefit rather than an automatic right, the administration aims to deter applicants from attempting to secure permanent residency while remaining in the US. Quantifying the Crackdown: Visa Revocations This policy shift is part of a broader, aggressive enforcement strategy that has already yielded significant numbers of visa cancellations. The administration has moved to shorten the duration of visas for students, cultural exchange visitors, and media workers, signaling a zero-tolerance approach to temporary stays. Visa Revocations: Over 100,000 visas have been revoked since President Trump returned to office in January. Policy Focus: Officers are now instructed to scrutinize visa violations, unauthorised employment, and fraud more rigorously. Resource Allocation: The agency claims the new guidance helps free up resources to focus on processing other immigration cases. Humanitarian Concerns and Industry Impact While the administration argues this reinforces the rule of law, immigrant advocacy groups have raised severe concerns about the practical implications. The policy threatens to separate vulnerable populations from safety nets, potentially forcing survivors of trafficking and abused children to return to dangerous environments while their applications are pending. Future Outlook: The Dual Intent Dilemma The guidance creates a complex future for holders of "dual intent" visas, such as H-1B workers or L-1 transferees, who are legally permitted to live in the US while seeking permanent residency. Although these categories are exempt from the immediate departure requirement, the memo clarifies that this status does not guarantee approval. This suggests a future where even dual-intent holders may face increased scrutiny and procedural hurdles before being granted permanent status.

The Road to Wembley Hull City owner Acun Ilicali is set to take his team to Wembley for a chance to secure a Premier League spot. The Turkish media mogul has been at the helm of Hull since January 2022 and has overseen a tumultuous period, including multiple coaching changes and playoff battles. The Coaching Carousel Ilicali has changed coaches several times, which some attributed to his ego. However, he claims it was due to his 'lack of ego,' as he aims to correct mistakes and find success. The current coach, Sergej Jakirovic, was appointed after a series of changes, and Ilicali is optimistic about the team's chances. Overcoming Adversity The team has faced challenges, including the 'spygate' scandal involving Southampton. Despite this, Hull secured sixth place on the final day and defeated Millwall to reach the playoffs. Ilicali is proud of his team's achievement and believes they have a good chance of promotion. Financial Commitment and Future Plans Ilicali has invested significantly in the team, spending over £100m and owning every player who started the recent win against Millwall. He is committed to long-term recruitment and is optimistic about the team's future prospects. Premier League Ambitions If Hull City secures promotion, Ilicali is aware of the challenges they will face in the Premier League. He cites Sunderland as an example of a team that can survive their first season and progress. Ilicali is not afraid of failure but is focused on helping the team learn and grow.

The Final Episode of The Late Show Celebrities, politicians, and New Yorkers paid their respects to Stephen Colbert as the Late Show aired its final episode on Thursday. The long-running chat show, which started back in 2015, was cancelled last year by CBS, purportedly because of a financial decision. But many believed it was a result of the network's increasing closeness with Donald Trump, who Colbert regularly criticised. A Bittersweet Goodbye Last night's episode saw the host bid an emotional farewell with the help of celebrity guests including Paul McCartney, Paul Rudd, Ryan Reynolds, and Bryan Cranston. "We love doing the show for you but what we really love is doing the show with you," he said to the audience at home. Colbert hosted more than 1,800 episodes of the Late Show, taking over the mantle from David Letterman. Tributes from Around the World Former president Joe Biden, who had previously guested on the show, also joined the chorus this week with a tribute on Instagram. "There aren't many who can make people think and laugh at the same time," he wrote. "For years, Stephen brought wit, heart, and honesty to late night television. America could always count on a laugh – and sometimes a needed reality check. Congrats on an incredible run, my friend." The Impact of Colbert's Comedy Jane Fonda was among celebrities featured in a video put together by her newly relaunched Committee for the First Amendment. "He made us laugh and he never flinched," the Oscar-winning actor said. "We've watched this administration suppress dissent repeatedly." Colbert already has his next gig lined up with the long-term JRR Tolkien fan set to co-write a new Peter Jackson-produced film tentatively titled The Lord of the Rings: Shadow of the Past. The Future of Late-Night Television The Late Show is being replaced by Comics Unleashed, an unscripted comedy series from comedian and media mogul Byron Allen. The entire set from the show is being donated to the Museum of Broadcast Communications in Chicago.

What is Immunotherapy? Immunotherapies are biological treatments that harness the immune system to prevent, control and fight diseases and other conditions. The most familiar are vaccines, which train the immune system to recognise targets such as invading pathogens. Other immunotherapies boost immune responses when they are too weak, or dampen them down when they are out of control. Still others draw on engineered immune cells or lab-made antibodies to disrupt disease processes. The Evolution of Immunotherapy Efforts to prevent disease by boosting the immune system date back thousands of years, but advanced therapies for a wide range of illnesses have come to the fore in the past two decades. A global registry of clinical trials listed 1,257 trials of immunotherapies between 2006 and 2016. The figure leapt to 4,591 in the past decade. How Do Cancer Immunotherapies Work? Cancer patients have seen great benefits from immunotherapies and dozens are now approved for more than 30 types of cancer. Some tumours evade the body’s defences by switching off immune cells, but antibody-based drugs – called checkpoint inhibitors – reactivate them so they can recognise and attack the malignancies. The Future of Immunotherapy: Beyond Cancer Researchers are now testing whether existing immunotherapies can help a broader range of patients. This includes treating allergies, infections, brain diseases, and autoimmune disorders. Some of the most exciting new immunotherapies draw on recent Nobel prizewinning work on regulatory T-cells, or Tregs, which can be used to dampen down immune responses. The Potential of Tregs in Immunotherapy Tregs are unusual immune cells that stand the immune system down once the threat has been dealt with. Therapies are in the pipeline for dementia and autoimmune diseases from type 1 diabetes and rheumatoid arthritis to lupus and chronic inflammation. The potential for Tregs is vast, and researchers believe that half of all deaths have a component that is immunological.

The Legacy of Mohamed Salah at Liverpool Mohamed Salah's departure from Liverpool marks the end of an era for the Egyptian forward, who has been a key player for the club since his arrival in 2017. With 257 goals and 441 appearances, Salah has cemented his place in Liverpool's history books. A Career of Achievements Third-highest goalscorer in Liverpool's history Won the Premier League title, Champions League, and numerous other honors Four-time Premier League Golden Boot winner Hat-trick of clean sweeps of the Professional Footballers' Association and Football Writers' Association footballer of the year awards The Impact of Salah's Departure Salah's departure has been marked by controversy, with the player publicly criticizing manager Arne Slot and the team's style of play. However, it is seen as a necessary move for both parties, with Salah seeking a new challenge and Liverpool looking to refresh their squad. The Future for Salah and Liverpool As Salah moves on to a new chapter in his career, Liverpool will look to build on the foundations he has helped establish. With a legacy that will be remembered for generations to come, Salah's impact on the club will not be forgotten.