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Young Vic artistic director Nadia Fall insists that theatres facing fiscal pressure must rely on daring, crowd‑pulling programming to restore solvency. Announcing a fresh slate of productions, she highlighted an anti‑Trump musical adaptation of Thelma & Louise as a flagship effort to attract diverse audiences. Since assuming leadership in 2025, Fall has overseen a £500,000 deficit that forced staff reductions. She stresses that while increased philanthropy is essential, the director’s most immediate lever is the choice of shows that can “program our way out of the crisis.” The upcoming musical, set to open on 3 September, features a score by Grammy‑winning Neko Case of the New Pornographers, and benefits from the involvement of original screenwriter Callie Khouri. Fall hopes the production’s feminist angle—positioned against the backdrop of “Trump’s America” and rolling back of women’s rights—will resonate with audiences. Other autumn highlights include Shedinburgh, an immersive showcase bringing Edinburgh Fringe talent such as Sara Pascoe and Inua Ellams to London for the first time, and Eurotrash, starring Ben Whishaw and Kathryn Hunter, adapted from Christian Kracht’s dark novel about a mother‑son road trip in the Swiss Alps. Fall also confirmed her direction of August Wilson’s Gem of the Ocean and the South London staging of Tiago Rodrigues’ father‑daughter drama La Distance. Additionally, a world premiere of Debbie Tucker Green’s near‑future dystopia Dissent will explore themes of surveillance and censorship that echo contemporary societal concerns. Her remarks came as a new Arts Council England report revealed a 64% decline in the number of plays touring England since 2019, underscoring the sector’s precarious state. While past successes—such as James Graham’s Punch, which earned two Olivier Awards—demonstrate the potential of strong programming, Fall warns that the split of box‑office receipts and Theatre Tax Relief often deters collaborative ventures across the country. Calling for “government‑level incentives” to make nationwide partnerships viable, Fall concluded that the future of UK theatre hinges on a combination of bold artistic choices, private investment, and supportive public policy.

A recent Cochrane review analyzing 17 clinical trials involving over 20,000 people with mild cognitive impairment or dementia has concluded that anti-amyloid drugs have a 'trivial' effect on cognition and dementia severity over 18 months.The review, which assessed seven anti-amyloid drugs, found that improvements in functional ability were 'small at best' and that the drugs caused more swelling and bleeding in the brain than the placebo.The findings are a blow to the new wave of drugs designed to slow Alzheimer's by clearing clumps of amyloid protein that build up in the brain. Despite initial hype, with some regulators approving drugs like lcanemab and donanemab, many countries have stopped short of providing them through public health services due to concerns over their effectiveness and cost.Critics of the review argue that it combines results from older, failed drugs with those from newer, more effective medicines, which may skew the conclusions. However, the review's authors defend their approach, stating that all the drugs aimed to remove amyloid from the brain and assessed the impact on patients in a similar way.The review's lead author, Edo Richard, notes that the effect sizes are too small for patients and caregivers to notice, and that the drugs are also 'burdensome' due to the need for regular intravenous drug infusions and MRI scans.Experts in the field, such as Robert Howard, express concerns that the drugs may not truly alter the course of Alzheimer's, and that it's unfair to raise expectations in patients. Meanwhile, Alzheimer's Research UK argues that the review's conclusions are limited by its methodology and that anti-amyloid treatments will not be the whole answer to curing Alzheimer's.

A Pakistani delegation headed by Army Chief General Asim Munir arrived in Tehran on Wednesday, bearing a fresh message from Washington and urging the launch of a second round of negotiations between the United States and Iran. The effort comes as the two‑week ceasefire that halted hostilities last week is set to expire on April 22, leaving a narrow window to end a war that has claimed more than 4,000 lives across the Middle East, primarily in Iran and Lebanon. The initial round of talks, held in Islamabad on April 11‑12, marked the most significant direct engagement between Washington and Tehran in decades. Mediated by Pakistan, the sessions lasted over 20 hours and featured both indirect and direct exchanges between U.S. Vice President JD Vance and senior Iranian officials led by Parliament Speaker Mohammad Bagher Ghalibaf. Despite covering core issues—nuclear programme, sanctions relief, frozen assets and control of the Strait of Hormuz—the talks concluded without a memorandum, with Vance asserting that Iran “did not accept our terms” and that the U.S. requires a “fundamental commitment” to forego nuclear weapons. President Donald Trump has described the conflict as “very close to being over” and hinted that a second round could resume within days, possibly in Islamabad. However, Pakistan’s Prime Minister Shehbaz Sharif is currently on a four‑day tour of Saudi Arabia, Qatar and Turkey to rally regional backing, making a rapid return to Islamabad uncertain. U.S. officials have offered an “in‑principle” agreement to extend the ceasefire, yet a Reuters‑cited source confirmed that Washington has not formally committed to an extension. Meanwhile, Turkish President Recep Tayyip Erdogan expressed optimism, stating that “there can be no negotiating with clenched fists.” Key sticking points remain: Nuclear programme: The United States and Israel demand a complete halt to uranium enrichment, accusing Iran of weaponization despite a lack of public evidence. Iran maintains its enrichment is for civilian use and cites its obligations under the 1970 Non‑Proliferation Treaty. Strait of Hormuz: One‑fifth of global oil and LNG passes through this chokepoint. Since the February strikes, shipping through the strait has dropped by 95 %. Iran permits passage for “non‑hostile” vessels and seeks the right to levy tolls, while the U.S. insists on unrestricted navigation. Lebanon/Hezbollah: Iran demands that Israel cease its offensive against Hezbollah. While Tehran claims the ceasefire covers Lebanon, both the United States and Israel reject this, and Israel continues attacks on Hezbollah positions. Complicating the diplomatic landscape, President Trump announced a naval blockade of Iranian ports, adding pressure on Tehran and potentially hindering any imminent talks. With the ceasefire deadline looming and regional actors issuing mixed signals, the prospects for a renewed U.S.–Iran dialogue hinge on whether Pakistan can secure a consensus among the parties before the window closes.

President Donald Trump announced on Fox Business that he will dismiss Federal Reserve Chair Jerome Powell should the governor refuse to leave his post when his term concludes on May 15. The statement, made during an interview with Maria Bartiromo, underscored the president’s willingness to act, saying he “has wanted to fire him, but I hate to be controversial… he will be fired.” Legal scholars and policy analysts quickly cautioned that the president’s threat is not grounded in statutory authority. Skanda Amarnath, executive director of the think‑tank Employ America, told Al Jazeera that the administration is already losing a court battle over an attempt to remove Fed Governor Lisa Cook and would likely face the same outcome if it pursued Powell’s removal. The controversy emerges as the Senate Banking Committee prepares to consider Kevin Warsh, Trump’s nominee to succeed Powell. Warsh’s hearing is scheduled for next Tuesday, but his confirmation remains uncertain. North Carolina Senator Thom Tillis has pledged to block the nomination until the ongoing federal criminal probe into Powell’s conduct concludes. If the Senate fails to confirm a new chair, Powell would remain at the helm until a successor is appointed, extending the period of tension between the White House and the central bank. Trump also referenced a separate investigation into a costly Fed building renovation, noting that U.S. Attorney Jeanine Pirro has not indicated any change in the probe’s direction. However, a federal prosecutor later reported that the investigation uncovered no evidence of criminal wrongdoing. Critics argue that Trump’s broader agenda seeks to increase political control over the Fed’s seven‑member board, aiming to install members who share his economic outlook. Currently, the president has appointed three board members, and one seat—held by Governor Stephen Miran—has technically expired, which would need to be vacated for Warsh to join. Powell has framed the investigation as a pretext to undermine the Fed’s independence in setting monetary policy, a charge that resonates with concerns about preserving the central bank’s autonomy amid political pressure. Overall, the standoff highlights a clash between executive ambition and the institutional safeguards designed to keep monetary policy decisions insulated from short‑term political influence.

Argentina’s justice system has reopened the case surrounding the death of football icon Diego Maradona, with prosecutors branding his medical team as “a bunch of amateurs” who missed a critical window to save him.The trial of seven healthcare professionals—doctors, psychologists and nurses—resumed on Tuesday in San Isidro, a suburb of Buenos Aires, after the original proceedings were annulled when a presiding judge was found to have participated in a documentary about the case.Maradona, who died in November 2020 at age 60 while recuperating from surgery for a brain clot, is alleged to have suffered from heart failure and acute pulmonary edema two weeks post‑operation. Prosecutor Patricio Ferrari asserted that the patient began to deteriorate 12 hours before his official death and that a timely transfer to a clinic could have prevented the fatal outcome.According to the indictment, the defendants’ decision to keep Maradona at home rather than in a hospital, coupled with a series of “omissions” described as “cruel,” constitutes homicide with possible intent. If convicted, each could face prison terms ranging from eight to 25 years.The new proceedings, expected to conclude by July at the earliest, will hear testimony from roughly 120 witnesses. Among the accused, former team doctor Leopoldo Luque and other staff members will be scrutinized for their role in the athlete’s care.Maradona’s family—daughters Dalma, Gianinna and Jana, and former partner Veronica Ojeda—attended the hearing, urging the courts to deliver “justice for Diego” and allow the legend to “rest in peace.” Outside, about 50 supporters waved Argentine flags and signs demanding accountability for the beloved “D10s.”Defense counsel Vadim Mischanchuk argued that the former star’s death resulted from a “progressive decline in his health” rather than medical malpractice, emphasizing that the condition was natural and unavoidable.Legal analyst Fernando Burlando, representing the Maradona family, highlighted the absence of a stethoscope on the legend’s chest during the critical two‑week period, using the instrument as a stark symbol of alleged negligence.The case revives national grief that first erupted when Maradona’s body lay in state at the presidential palace, drawing tens of thousands of mourners amid the COVID‑19 pandemic.

The Australian Matildas concluded their groundbreaking Fifa Series tour with a hard-fought 2-0 win over Kenya in Nairobi's Nyayo Stadium. Sam Kerr scored her 75th international goal, which proved to be the softest of her career, as she set her team on the path to victory.In front of a lively crowd of 20,000 Kenyan fans, the Matildas secured their win with goals from skipper Kerr and midfielder Clare Wheeler in each half. Despite their ranking difference - Australia is 15th globally while Kenya is 128th - the Kenyan team showed resilience, particularly in the first half.Kerr's goal came in the 25th minute after a corner from Jamilla Rankin found her unmarked in the box. The Kenyan goalkeeper, Lillian Awuor, made a critical error, allowing the ball to dribble through her fingers.The match turned controversial in the 60th minute when Caitlin Foord's goal was disallowed for reasons that left everyone in the stadium, except the referee, perplexed. Foord had powered the ball into the net from a narrow angle, but the referee ruled it hadn't crossed the line.Clare Wheeler's second goal for Australia came in the 54th minute after Foord's individual effort created the opportunity. Wheeler's neat footwork allowed her to evade defenders and slot the ball home.The win marked a significant milestone for Alanna Kennedy, who earned her 150th cap and was named captain for the day. The Matildas' coach, Joe Montemurro, reflected on the team's performance, acknowledging both the positives and the controversy.

President Donald Trump announced on Fox Business that he will dismiss Federal Reserve Chair Jerome Powell if the central‑bank chief does not vacate the post by the statutory end of his term on May 15. “I’ll have to fire him, OK, if he’s not leaving on time,” Trump said, adding that he had previously held back the decision to avoid controversy. Powell, who has just over a month left in his tenure, has repeatedly been criticized by Trump for what the president calls a “bad job” and for refusing to lower interest rates despite Trump’s repeated demands since his return to the White House in January 2025. In January, Trump nominated former Fed governor Kevin Warsh to replace Powell. Warsh, known for his criticism of the Fed’s relatively high rates, is expected to align more closely with Trump’s push for rate cuts. His confirmation hearing before the Senate Banking Committee is slated for April 21, but the outcome remains uncertain. Republican Senator Thom Tillis of North Carolina, a member of the banking committee, has signaled he will block Warsh’s nomination until the Department of Justice concludes its criminal investigation into alleged misconduct surrounding the Fed’s headquarters renovation in Washington, D.C. Tillis described the probe as “reaching the point of absurd,” yet insists the investigation must be resolved before moving forward. The probe appears active: prosecutors made an unannounced visit to the construction site this week, as reported by the Wall Street Journal, underscoring the seriousness of the inquiry. During the same interview, Trump dismissed the investigation’s relevance, claiming the project was “probably corrupt, but what it really is is incompetence,” and questioned whether a $25 million renovation could balloon to a $4 billion expense. Powell responded in January with a rare public rebuke, labeling the investigation a “pretext” aimed at pressuring the Fed to lower rates. He warned that political intimidation could jeopardize the Fed’s ability to set monetary policy based on economic evidence. The legal backdrop adds another layer of uncertainty. The Supreme Court has yet to rule on Trump’s authority to fire a Fed board member without cause—a question that resurfaced after the president’s attempted removal of Fed governor Lisa Cook last summer. Justices appeared skeptical of such unilateral action during oral arguments in January. With the Fed’s independence at stake, the coming weeks will determine whether Trump’s threat translates into action, whether Warsh can secure Senate confirmation, and how the renovation investigation will influence the broader debate over political interference in U.S. monetary policy.

On Wednesday, Everton marked the 37th anniversary of the Hillsborough tragedy by installing a permanent memorial at the newly‑named Hill Dickinson Stadium, dedicated to the 97 Liverpool supporters who lost their lives.Representatives of the victims' families and officials from Liverpool FC were invited to a solemn ceremony where a plaque was affixed to the South Stand, formally unveiling the tribute.Former Liverpool manager Sir Kenny Dalglish and club legend Ian Rush laid floral offerings on behalf of Liverpool, while Hillsborough campaigner and Everton supporter Stephen Kelly—who lost his brother Michael in the disaster—placed a wreath at the site.Everton legend Graeme Sharp, club ambassadors Ian Snodin and Graham Stuart, chief executive Angus Kinnear, and Liverpool counterpart Billy Hogan also attended, underscoring the joint remembrance. The event precedes the first Merseyside derby at Hill Dickinson Stadium, scheduled for Sunday.Later, Liverpool’s players, staff and head coach Arne Slot observed a moment of silence at the club’s training ground at 3:06 pm, the exact minute the 1989 match was halted. To conclude the tribute, 97 balloons were released from Anfield’s centre circle, symbolising each victim.

Former Treasury Secretary Janet Yellen sharply criticized President Donald Trump’s repeated calls for the Federal Reserve to slash borrowing costs, likening the approach to the fiscal tactics of a “banana republic.”Trump has publicly urged the central bank to deliver the lowest interest rate in the world, arguing that cheaper financing would ease the service burden on the United States’ staggering $39 trillion debt.Speaking at an HSBC investor summit in Hong Kong, Yellen asked, “How often does the president of a developed country demand that interest rates be set to reduce debt‑service costs? This is what you hear in a banana republic.” She warned that such political meddling could unleash inflation if the Fed’s independence is compromised.The Fed, under Chair Jerome Powell, last lowered its policy rate in December to a range of 3.5 %–3.75 %. However, policymakers are growing uneasy about inflationary pressures, especially as the ongoing Iran conflict threatens oil supplies.Powell is slated to step down next month, but his successor—Trump’s nominee Kevin Warsh—has yet to secure Senate confirmation. Powell has indicated he will remain in his role if a replacement is not confirmed, and he may continue as a Fed governor until a pending Department of Justice investigation concludes.Trump has openly dismissed the idea of Powell staying on, telling Fox Business that he would “have to fire him” if the chair does not leave. Powell, for his part, describes the DOJ probe as a “pretext” aimed at pressuring the Fed to cut rates.Warsh, who argues that potential productivity gains from artificial intelligence could justify lower rates, faces skepticism from Yellen, who doubts he commands the same respect as former Fed chair Alan Greenspan. She noted, “Greenspan was widely respected for his expertise; I don’t think Warsh walks in with that level of credibility.”Trump’s broader effort to reshape the Fed board includes an attempt to remove Governor Lisa Cook, who is currently facing a Supreme Court case over alleged mortgage fraud.Meanwhile, finance ministers and central bankers have gathered in Washington for the International Monetary Fund’s spring meetings. Bank of England Governor Andrew Bailey warned that rising oil prices, driven by the Iran conflict, constitute a “major supply shock” that central banks must assess carefully.The IMF has cautioned that a prolonged closure of the Strait of Hormuz could trigger a global recession, underscoring the interconnected risks of geopolitical tensions, sovereign debt, and monetary policy decisions.