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The Challenges of FDA Approval Surviving the long road to FDA approval isn’t just about building great technology — it’s about keeping your team motivated, finding the right investors, and learning how to operate when timelines are uncertain. Lessons from BioticsAI This week on Build Mode, Isabelle Johannessen sits down with Robhy Bustami, co-founder and CEO of BioticsAI, a Startup Battlefield-winning company building an AI copilot for ultrasound to help detect fetal abnormalities. From a $100,000 prototype to FDA clearance, Bustami shares what it actually takes to build in one of the most regulated industries in the world. Building a Medtech Startup In this episode, they break down what it really looks like to build a medtech startup, including where you can’t “move fast and break things” and that every milestone takes time, coordination, and trust. Key Takeaways Team motivation is crucial during the long FDA approval process Finding the right investors is essential for medtech startups Adaptability is key when dealing with uncertain timelines Future Outlook As the medtech industry continues to evolve, startups like BioticsAI will play a critical role in shaping the future of healthcare technology. With the right approach and mindset, these companies can overcome the challenges of FDA approval and make a lasting impact.

Salesforce's AI Roadmap Strategy Artificial intelligence continues to advance at a dizzying clip, forcing enterprises to develop and release new products quicker than ever or risk becoming irrelevant to a faster-moving competitor. Salesforce believes it has found a strategy that allows it to keep up even if it isn’t clear where AI is headed next. The customer management software giant is crowdsourcing its AI roadmap in real time. Crowdsourcing AI Development Salesforce is certainly not the only company to work intimately with its customers for feedback on its products. However, it’s notable considering the sheer size of the company, the pace of new product launches or fixes to existing ones, and the granular level of these relationships. These aren’t annual or even quarterly discussions. Salesforce is meeting with some customers as often as once a week. The Benefits of Customer Feedback “The 18,000 customers are a wellspring of information and a wealth of information that is really needed to get to customer success,” Jayesh Govindarajan, executive vice president at Salesforce AI, told TechCrunch in a recent interview. “The stack that we’ve built has resonated with these customers. Over time we can get context to be better, and as it gets better, and LLMs get better, agent systems do more and more fully autonomous behaviors. That’s a long-running innovation track and we’re going to invest in that.” Rapid Product Releases Salesforce credits its customers for the rate of its product releases. The company told TechCrunch that by letting its customers lead the way, it is able to build an AI product roadmap that can quickly react to where AI technology is headed. Real-World Applications Engine, a travel management platform, meets with Salesforce weekly and gets access to AI tools before they’re released. PenFed, a federal credit union, developed an IT service management (ITSM) workflow on its own using existing tools and agents in Agentforce. The Future of AI Development This strategy also allows the company to roll out solutions and workflows built by users to its broader customer base too. However, it relies on the classic service sentiment that the customer is always right. Salesforce is hoping they are despite many enterprises still figuring out what role AI will play in their business, and many having yet to find value from the tech.

The Road to a Fourth Term The Confederation of African Football (CAF) says it is backing FIFA President Gianni Infantino’s bid for a fourth term as head of football’s global governing body. In a statement after a meeting before the FIFA Congress in Vancouver, CAF said it had “unanimously agreed” to support Infantino when the FIFA chief stands for re-election in 2027. Infantino's Background and Previous Terms Infantino took over as head of FIFA in 2016 in the wake of the corruption scandal that led to the downfall of his predecessor Sepp Blatter. He was re-elected to the post in 2019 and 2023. The Exception to FIFA's Term Limit Although FIFA statutes limit FIFA presidents to three terms in office, Infantino is allowed to run for re-election next year after the body ruled that his first, partial term from 2016 to 2019 after Blatter’s ouster did not count towards the total. International Support for Infantino CAF’s decision to support Infantino comes after South American football’s governing body, CONMEBOL, also pledged to support the Swiss-Italian official earlier in April.

The Emotional Departure of a Tottenham CaptainBethany England, the captain of Tottenham Hotspur Women, has confirmed her departure from the club at the end of the current season in an emotional video message shared with fans. The 31-year-old striker, who has been instrumental to the team's success during her three and a half years at the club, expressed her deep appreciation for the support she received during her time at Tottenham.Strategic Squad Evolution at TottenhamThe club's decision not to renew England's contract is part of a broader strategy to evolve the squad with younger players. Multiple sources have emphasized that Tottenham is expected to be aggressive and highly ambitious in the upcoming transfer market. This move comes alongside several other confirmed summer exits, including Amy James-Turner, Luana Bühler, Charlotte Grant, Josefine Rybrink, and Kit Graham, indicating a significant transformation of the squad.England's Remarkable Statistical LegacyDuring her time in the Women's Super League, England has established herself as one of the competition's most prolific scorers. She is the WSL's second-highest goalscorer in the division's 15-year history, with 89 goals—eight behind record holder Vivianne Miedema. In March 2026, she became only the seventh player to reach 200 WSL appearances, a testament to her consistency and quality at the highest level of women's football in England.Impact on Tottenham and Women's FootballEngland's departure represents a significant loss for Tottenham, both on and off the pitch. During her tenure, she helped the team reach the 2024 Women's FA Cup final and was crucial in steering the team clear of relegation during her first six months after arriving from Chelsea. Her leadership has been described as having "shaped a defining era" in Tottenham women's football history, driving up standards, professionalism, and desire within the squad.Future Outlook for England and TottenhamAs a free agent with an impressive track record, England is likely to be highly sought after by other clubs. Her experience, goal-scoring prowess, and leadership qualities make her an attractive addition to any team. Meanwhile, Tottenham appears set on a summer recruitment drive to rebuild their squad with younger talent, signaling a new direction for the club as they aim to compete at the highest level of women's football in the coming seasons.

Public Anxiety Peaks as AI Quality Concerns Reach a New High As the U.S. midterm elections loom, voters are increasingly uneasy about artificial intelligence. 57% of registered voters say the risks of AI outweigh the benefits, according to an NBC News poll. Younger adults are even more skeptical: 61% of those under 30 believe more AI will make people worse at creative thinking, per a Pew Research survey. Poll Data Shows Majority Demand Stronger AI Regulation 57% of voters think AI risks outweigh benefits (NBC News). 61% of adults under 30 fear AI will erode creative thinking (Pew). 74% believe the government is not doing enough to regulate AI (Quinnipiac). These figures illustrate a growing political cohort that is ready to back concrete policy measures. Economic and Cultural Costs of AI‑Generated “Slop” Critics label the flood of low‑effort, AI‑generated content as “AI slop”—digital output that appears productive but later requires costly correction. A Goldman Sachs study found AI’s net impact on productivity to be a rounding error, while the Harvard Business Review warns that “workslop” drains human creative labor. Beyond productivity, slop threatens cultural ecosystems: fake music bands on Spotify, AI‑written books crowding Amazon, and inaccurate Google “AI overviews” that generate millions of wrong answers per hour. Legislative Proposal: A 1% Tax on Generative AI Output Mike Pepi proposes a straightforward levy: any company that furnishes or hosts generative AI content would pay an annual ~1% tax on its revenue. The five largest public AI firms—Nvidia, Google, Apple, Microsoft and Meta—collectively hold about $18 trillion in market value, meaning a 1% tax could generate roughly $180 billion each year. Revenue would flow into a publicly controlled fund that distributes grants to cultural institutions, artists, journalists, educators, and research projects—the very sectors whose data train these models. Outlook: From Tax to a Cultural Renaissance? If enacted, the “slop tax” could create a feedback loop: AI firms contribute to the public good, while creators receive resources to produce higher‑quality work. The proposal also offers Democrats a tangible policy win ahead of the midterms, potentially restoring trust among younger voters who feel betrayed by AI’s promises. While broader AI regulation remains fragmented, a targeted levy on the most egregious output may be the pragmatic first step toward a healthier digital ecosystem.

The Escalation of Xenophobic Violence in South AfricaThe recent wave of anti-immigrant attacks and protests marks a significant escalation in social unrest within South Africa. What began as localized tensions has rapidly evolved into a broader crisis, drawing international attention to the country's internal security challenges. The violence targets foreign nationals, primarily from neighboring African nations, leading to widespread displacement and a breakdown of community trust.Recent Escalations and Community DisplacementTargeted Attacks: Reports indicate that mobs have targeted shops and residential areas inhabited by foreign nationals, resulting in looting and destruction of property.Police Response: Law enforcement agencies have been deployed to quell the violence, though reports suggest a slow response in some hotspots.Humanitarian Impact: Thousands of immigrants have been forced to flee their homes, seeking refuge in churches or temporary shelters as safety remains a primary concern.Economic and Demographic Strain AnalysisWhile the immediate trigger for these attacks is often framed as xenophobia, the underlying economic factors are undeniable. The influx of foreign labor has created intense competition for low-skilled jobs and resources in a struggling economy. Analysts suggest that the current economic climate is amplifying existing prejudices, turning frustration with unemployment into directed hostility against the immigrant population.Political and Regional RamificationsThis crisis poses severe challenges for the South African government. It undermines the narrative of a progressive, inclusive democracy and strains diplomatic relations with African Union partners. The inability to protect foreign residents effectively damages the country's reputation as a safe haven on the continent and complicates regional trade and migration agreements.Future Outlook: Policy Reform and Social CohesionLooking ahead, the situation requires immediate intervention to prevent further escalation. Experts predict that without addressing the root causes—specifically economic disparity and job creation—these cycles of violence will continue. The government faces a critical test in implementing policies that foster social cohesion while simultaneously creating economic opportunities for all citizens, regardless of origin.

The Festival of Britain: A New Beginning The Festival of Britain, a grand celebration of British culture and resilience, officially opened on May 4, 1951. The event was marked by a service of dedication at St Paul's Cathedral, where King George VI proclaimed the festival open in a broadcast speech. The King's Address In his address, the King reflected on the contrast between the Victorian era and the hardships faced by Britain during World War II. He emphasized that despite these challenges, the festival represented a symbol of Britain's enduring courage and vitality. The Royal Festival Hall: A New Cultural Landmark Later that evening, the King and Queen attended a service of dedication at the Royal Festival Hall, a newly built concert hall on the South Bank of the Thames. The hall was formally opened with the unveiling of a tablet, and the King and Queen heard the first concert in the new hall. The Festival's Impact The Festival of Britain was not just a celebration of British culture but also a showcase of the country's determination to rebuild and move forward after the devastation of World War II. The festival's impact was felt across the nation, with various events and exhibitions held throughout the country. A New Era for Britain The Festival of Britain marked a significant moment in British history, symbolizing the nation's resilience and determination to rebuild and thrive in the post-war era. The festival's legacy continued to inspire future generations, and its impact on British culture and society remains to this day.

The Curated April Reading List from Writers and Readers The Guardian asked a handful of authors and avid readers what they were enjoying in April, producing a vivid snapshot of the books that are shaping conversations in literary circles today. Highlights from Emerging and Established Authors Luke Kennard praises All In by Claire Powell – a meta‑beach read that captures contemporary Englishness with merciless affection. Luke Kennard also recommends Ghosts by Argentine writer César Aira, a short novel about squatters haunted by beautiful specters. Luke Kennard is reading A Place of Greater Safety by Hilary Mantel, a vivid portrait of Camille in the French Revolution. Rosie (Guardian reader) highlights Jesus Christ Kinski by Benjamin Myers, a layered tale of performance, cancel culture, and artistic ego. Sophie Ratcliffe (writer) shares her current obsessions: The Aspern Papers by Henry James, Antiquities and Other Stories by Cynthia Ozick, and Calamities by Renee Gladman. Kate (Guardian reader) recommends Flashlight by Susan Choi, a mystery that weaves Japanese culture, Korean occupation, biracial identity, and MS. What the Recommendations Reveal About Current Literary Trends Analyzing the list shows three clear patterns: Meta‑narrative & genre‑blending: Both All In and Flashlight combine genre conventions with literary depth. International & translated voices: César Aira and Cynthia Ozick illustrate growing appetite for non‑English perspectives. Historical re‑examination: Works by Hilary Mantel and Benjamin Myers signal renewed interest in revisiting past eras through contemporary lenses. Why These Picks Matter for the Publishing Landscape Publishers can read this roundup as a signal that: Investments in translation rights are likely to yield strong critical and commercial returns. Books that straddle literary and genre expectations are resonating with both writers and readers, encouraging hybrid marketing strategies. Historical fiction that tackles under‑explored viewpoints (e.g., the French Revolution from a musician’s angle) is gaining traction, suggesting editorial room for fresh archival projects. Looking Ahead: What April’s Choices Signal for 2026 Reading Habits If the April selections are any indication, the second half of 2026 will likely see: A surge in short‑form and novella‑length works that deliver intense, self‑contained experiences. Greater demand for cross‑cultural narratives, especially those that blend personal memoir with broader historical context. Continued enthusiasm for authors who can weave social commentary into compelling storytelling, positioning books as both entertainment and cultural critique. Publishers, booksellers, and literary festivals would do well to spotlight these trends, ensuring that the voices highlighted this April remain at the forefront of the conversation.

The Military Court Begins Trial of Soldiers Accused of Acid AttackThe trial of four soldiers linked to the Strategic Intelligence Agency started on Wednesday in a Jakarta military court, charging them with a premeditated acid assault on activist Andrie Yunus that left him blind in one eye and burned over 20% of his body.Attack date: 12 March 2026Victim: Andrie Yunus, 27‑year‑old human‑rights activistAccused: Four soldiers, all tied to the Strategic Intelligence AgencyLegal Stakes: Charges, Potential Sentences, and Prosecutorial ClaimsProsecutors allege the soldiers acted out of anger over Yunus’s anti‑military activism, not under official orders. Each faces a maximum of 12 years in prison for premeditated assault. The agency’s chief has resigned, though no public reason was given.Broader Implications for Indonesia’s Democratic BackslidingThe case is being watched as a barometer of Indonesia’s shifting civil‑military balance. Under President Prabowo Subianto, legislation now permits active‑duty officers to hold civilian posts, reversing reforms from the post‑Soeharto era. Analysts warn this erodes civilian oversight and fuels a climate of intimidation for critics.International Reaction and Human‑Rights ConcernsThe United Nations condemned the attack, with High Commissioner for Human Rights Volker Turk calling it a “cowardly act of violence” and Special Rapporteur Mary Lawlor labeling it “horrific.” Amnesty International highlighted the trial’s location in a military court as a risk to impartiality and noted that at least 14 individuals may have been involved, yet only four are indicted.What the Future Holds for Civil‑Society Oversight of the MilitaryRights groups argue the trial’s outcome will set a precedent for accountability. If the soldiers receive substantive sentences, it could embolden civil‑society calls for tighter civilian control. Conversely, a lenient verdict may deepen fears of impunity and accelerate democratic decline, prompting further international scrutiny and possible sanctions.