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The UK is on the brink of a medicine shortage crisis, with experts warning that the country is just weeks away from feeling the effects of the ongoing conflict in Iran. The war has already disrupted the supply of essential raw materials, including oil, gas, crop fertiliser, and helium.The pharmaceutical industry, which relies heavily on imports, is particularly vulnerable to these disruptions. India, known as the 'pharmacy of the world', produces a significant proportion of generic drugs and active pharmaceutical ingredients (APIs) used globally. However, with the Strait of Hormuz largely closed due to the conflict, the transportation of these vital supplies is becoming increasingly difficult.Medicine prices are also expected to rise as a result of the conflict. The US-Israel war on Iran has doubled air freight costs, which could make some medicines loss-making to supply to the NHS. While suppliers have long-term pricing agreements with NHS hospitals, they have more flexibility to increase prices for drugs supplied to GP practices and pharmacies.The UK's reliance on imported medicines is significant, with about half of its medicines produced domestically, a third coming from India, and another chunk from the EU. During the Covid pandemic, paracetamol and other painkillers were in short supply in Britain and elsewhere, as drugmakers in India struggled to keep up with demand.Medical distributors typically stock six to eight weeks of supplies to avoid shortfalls, but if the conflict drags on, drug shortages could emerge in only a few weeks' time. Experts warn that the overall ripple effect on the industry is significant, with the patient ultimately picking up the tab, either directly or via public health systems like the NHS.

Mohaddeseh Fallahat recalled the ordinary morning of February 28 when she prepared her children for school, never imagining it would be the last time she would see them alive. That simple morning routine now haunts her as she struggles to cope with the devastating loss of her two children.Speaking through tears to the United Nations Human Rights Council in Geneva via videolink, Fallahat described the unbearable pain of sending her children off with a smile, only to be met with silence. "My heart burns with pain," she shared, as the memory of their final words—"Mum, come pick us up after school"—repeats endlessly in her mind.Her children were among more than 170 people killed when United States Tomahawk missiles struck the Shajareh Tayyebeh Girls' School in Minab, southern Iran, during the initial hours of the US-Israeli assault. The majority of victims were schoolgirls, marking one of the deadliest attacks on educational facilities in recent memory.Iran's Foreign Minister Abbas Araghchi addressed the council with strong condemnation, asserting that the attack was no mere miscalculation. "No one can believe that the attack on the school was anything other than deliberate and intentional," he stated, pointing to the advanced precision technologies claimed by American and Israeli forces.Araghchi accused the US and Israel of "slaughtering [victims] in cold blood" and committing "the worst humanitarian crimes with impunity." He called on UN member states to denounce what he described as a "blatantly unjustified" war on Iran, warning that indifference would bring no lasting security or peace.UN special rapporteur on the right to education, Farida Shaheed, presented evidence suggesting the school was "each struck individually by precision munition," indicating intentional targeting. However, ongoing investigations suggest the attack may have resulted from "outdated intelligence" used by the US military.Shaheed emphasized that "the killing of children can never, ever be justified" and highlighted the broader impact on education in Iran, where more than 600 schools and education facilities have been destroyed or severely damaged by US-Israeli attacks, with at least 230 children and teachers confirmed dead.UN Human Rights chief Volker Turk reinforced that targeting schools constitutes a grave violation of international law, stating: "Whatever differences countries have, we can all agree they will not be solved by killing schoolchildren."

The US men's national team is facing a critical center-back shortage ahead of their friendlies against Belgium and Portugal, mirroring the kind of injury crisis they might encounter at the World Cup. Defenders Chris Richards and Miles Robinson are out due to injuries, leaving Pochettino with only three healthy natural center-backs: Tim Ream, Auston Trusty, and Mark McKenzie.Pochettino is considering tactical adjustments and alternative players to fill the gap. He mentioned that the absences could create an opportunity to try players at different spots, including Joe Scally, a right-back who has played as a right center-back in a three-man backline, and Tanner Tessmann, a midfielder who has filled in as a center-back for Lyon on several occasions.The team's strategy and player versatility will be put to the test as they prepare for the World Cup. Pochettino emphasized the importance of being prepared for such situations, stating, “When we talk about being right in the players that you pick … if this is happening in a World Cup, you need to see all the options that you have.”The friendlies against Belgium and Portugal will serve as a crucial test for the team's depth and adaptability, with potential implications for the World Cup roster. The USMNT will have to make the most of their current squad, as there are no reinforcements coming.

Brendan Gleeson has been named best actor at the Critics' Circle theatre awards for his West End debut in Conor McPherson's pub drama The Weir. He beat fellow nominees including Bryan Cranston and Paapa Essiedu, both recognised for All My Sons, and James Hameed and Arti Shah, the duo who together portray Paddington in the new musical about Michael Bond's bear.The Weir, directed by McPherson, was entirely omitted from the nominations for this year's Olivier awards and is being turned into a film with Gleeson and the rest of the West End cast.All My Sons, a critically adored production of Arthur Miller's 1946 classic at Wyndham's theatre, won in two categories at the Critics' Circle awards: best revival of a play or musical and best director for Ivo van Hove. A new production of Stephen Sondheim and James Lapine's Into the Woods, directed by Jordan Fein at the Bridge theatre, also won two prizes – best designer (Tom Scutt) and the inaugural award for best ensemble or cast.The winners, voted for by professional theatre critics, were revealed at a ceremony at the National Theatre in London on Thursday. Paddington: The Musical, with music and lyrics by Tom Fletcher and book by Jessica Swale, won best new musical. James Graham's Punch, based on the real story of a fatal blow, received the Michael Billington award for best new play (named in 2019 in honour of the Guardian's theatre critic after he stepped down from reviewing). Ava Pickett won most promising playwright for her Tudor drama 1536, which was staged at the Almeida theatre in London in 2025, transfers to the West End in May and is being turned into a BBC drama series.Rosamund Pike saw off competition from Kate Fleetwood (Into the Woods), Marianne Jean-Baptiste (All My Sons) and Rachel Zegler (Evita) to win best actress for her acclaimed performance as a judge in Suzie Miller's Inter Alia. Ruby Ashbourne Serkis was named most promising newcomer for her performance in a revival of Tom Stoppard's Indian Ink which opened at Hampstead theatre days after the revered playwright's death. The award for best Shakespearean performance went to Hayley Atwell for her Beatrice (alongside Tom Hiddleston, nominated for the same prize, as Benedick) in Much Ado About Nothing at Theatre Royal Drury Lane.

Marcelo Bielsa, the charismatic and intense manager of Uruguay, returns to England for a friendly match against the host team on Friday. This visit comes four years after he left Leeds United, where he had a hugely successful stint, earning promotion to the Premier League and restoring the fanbase's faith in football. Bielsa's managerial style, known for its radicalism and emphasis on playing the right way, has been both admired and criticized. His teams are known for their high-intensity performances, but also for the physical and mental toll it takes on players. His departure from Leeds United was marked by a boom-bust pattern, where his teams initially perform well but eventually suffer from fatigue and decreased results. During his time at Leeds United, Bielsa was praised for his commitment to social responsibility, having players pick up litter to instill a sense of community and responsibility. His approach to football extends beyond the pitch, emphasizing the role of the sport in society. Uruguay's recent performances have been inconsistent, with a 5-1 friendly defeat to the USA in November 2023 being a significant low point. Luis Suárez, a key player, publicly criticized Bielsa, accusing him of isolating players and creating a culture of fear. Suárez's retirement from international football and subsequent comments have added to the uncertainty surrounding Bielsa's tenure. The upcoming friendly against England provides an opportunity for Bielsa to address these concerns and work towards restoring confidence in his team. Getting key players back in form, such as Darwin Núñez, who has not scored an international goal in 11 games, will be crucial. Bielsa's third World Cup may be his last chance to make a significant impact on the global tournament, and he will be looking to make a strong impression.

The concept of joules, named after Victorian-era physicist James Prescott Joule, has evolved significantly over time. From a simple unit to describe the effort required to pick an apple off the floor, it has grown to encompass larger units such as kilojoules, megajoules, gigajoules, terajoules, petajoules, exajoules, and now zettajoules. However, humanity's increasing energy consumption and its impact on the planet's energy balance have far outpaced our understanding and management of these growing energy levels.

Jaxon Smith-Njigba, the star wide receiver for the Seattle Seahawks, has secured a monumental contract extension. The deal, valued at $168.6m over four years, includes $120m guaranteed, making him the highest-paid wide receiver in NFL history.The annual salary of $42.15m surpasses that of Cincinnati Bengals star Ja’Marr Chase, who averages $40.25m per season on his four-year, $161m deal. This significant increase reflects Smith-Njigba's value to the Seahawks and his impressive performance on the field.In February, Smith-Njigba expressed his expectation of becoming the highest-paid at his position, stating, “I think I deserve to be the highest-paid at my position, just what I give to the game and the community, I give it my all. And I think that’s worth a lot, lot more.” He emphasized his passion for the game, noting, “I would play this game for free, I love this game so much, but you don’t have to. I’m learning to be a good businessman, and we need that check at the end of the day.”Smith-Njigba's achievements include being the NFL Offensive Player of the Year in 2025, setting franchise records with 119 receptions and 1,793 receiving yards, and catching 10 scoring passes. His playoff performance was stellar, with 17 catches for 199 yards and two touchdowns, including a strong showing in Super Bowl LX.At 24 years old, Smith-Njigba has accumulated 282 receptions for 3,551 yards and 20 touchdown catches in 51 NFL games. As the 20th overall pick in 2023 out of Ohio State, he is a two-time Pro Bowl selection, solidifying his status as a top player in the league.

Graham Napier, a former Essex all-rounder, recalls the 2008 T20 Blast match where he scored 152 not out off 58 balls, breaking the English record for the highest score in T20 cricket. This impressive performance caught the attention of England's selectors and teams from the Indian Premier League (IPL), including Mumbai Indians, who were interested in signing him.Napier, who didn't have an agent at the time, was eventually signed by Mumbai Indians for an undisclosed fee. However, his availability was curtailed by Essex, and he only played one game for Mumbai, scoring 15 runs and taking one wicket. Napier reflects on the experience, stating that he was frustrated by not being allowed to participate in the auction and that the hype surrounding his performance was intense.Tymal Mills, a veteran of franchise T20 leagues, had a more successful auction experience, being picked up by London Spirit for £130,000 in the Hundred auction. Mills had previously been sold to Royal Challengers Bangalore for £1.4m in the 2017 IPL auction. However, he admits that he didn't deliver on his whopping auction fee in 2017, taking only five wickets in five games before injury struck.Mills offers advice to young players, including James Coles, who was signed by London Spirit for £390,000. Mills cautions that the auction process can be bruising and that players must be prepared for the highs and lows of the experience.Napier, now a fire safety officer in Suffolk, has no regrets about his career, stating that he's proud of his achievements and the experiences he had. He notes that loyalty was a significant factor in his career, playing for the same team from age 10 to retirement at 36.

The world of ballet has long been associated with a specific physical ideal, particularly when it comes to foot shape. However, dancers with flat feet are proving that this condition is not a barrier to success. For Claudia Efemini, picking up her ballet shoes again after six years was a bittersweet experience. While she was excited to revisit a childhood hobby, she was also disheartened by the memory of being discouraged from pursuing ballet due to her flat feet.The industry's obsession with 'perfect' feet, characterized by high arches, has led some dancers to use fake arches, or farches, to create the illusion of more flexible feet. However, flat-footed dancers like Alex Maureen and Ruth Essel are thriving in the ballet world. Maureen, a performer and dance instructor at New York University, and Essel, founder of Pointe Black, a London-based ballet school, reject the notion that flat feet are an obstacle to success.Research shows that Black people are more prone to having flat feet, but Essel and Maureen's experiences demonstrate that this condition does not predetermine one's potential in ballet. Through education and self-advocacy, they have overcome discouraging beliefs about their feet and developed strategies to work with their body types. Essel, with a background in psychology, learned about anatomy and exercises to strengthen her ankles and improve foot mobility.Injury prevention is crucial for flat-footed dancers, who tend to land on their heels. Maureen and Essel stress the importance of educators adapting to different body types and seeking specialist advice when needed. They also highlight the need for greater diversity in ballet, including more Black pointe shoe fitters and physiotherapists.Maureen and Essel have developed checklists for their students before they start using pointe shoes, ensuring a comfortable and supportive fit. As Maureen advises, 'You just need your shoe to work for you, not against you.' For aspiring ballerinas with flat feet, Maureen's words of encouragement are 'Give yourself grace. Be kind to yourself.'