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The New Tool for Obesity-Related Disease Risk A new tool developed by UK researchers can help identify individuals most at risk of obesity-related diseases, such as type 2 diabetes, gout, and stroke. This tool uses a type of AI called interpretable machine learning to analyze data from nearly 200,000 participants of the UK Biobank project. How the Tool Works The researchers applied the AI tool to data from participants with a BMI of 27 or greater, identifying 20 health, lifestyle, and demographic features that could predict the 10-year risk of 18 different obesity-related complications. These features include age, sex, total cholesterol, and creatinine levels. The Data Analysis The team tested the validity of the tool, dubbed Obscore, using UK Biobank data and datasets from two independent health studies. The results showed that participants with the same age, sex, and BMI can have very different risks for various obesity-related conditions. The Impact Analysis The tool could help inform strategies for prioritizing who should receive weight-loss interventions, particularly in cases where access to NHS treatments is limited. According to Prof Nick Wareham, the tool is not about extending the use of particular therapies, but rather about developing and validating a score that can help with more rational resource allocation. The Prediction The researchers believe that their tool could be useful for prioritizing individuals who would benefit most from weight-loss medications. However, Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, noted that substantial further development and validation will be required before such an approach can be translated into routine clinical practice.

The Lead Pakistan has opened six overland transit routes for goods destined for Iran, formalizing a road corridor through its territory as thousands of containers remain stranded at Karachi port due to the US blockade of Iranian ports and ships trying to pass through the Strait of Hormuz. Pakistan's New Transit Routes The Ministry of Commerce issued the Transit of Goods through Territory of Pakistan Order 2026 on April 25, bringing it into immediate effect. The order allows goods originating from third countries to be transported through Pakistan and delivered to Iran by road. The six designated routes link Pakistan's main ports, Karachi, Port Qasim and Gwadar, with two Iranian border crossings, Gabd and Taftan, passing through Balochistan via Turbat, Panjgur, Khuzdar, Quetta and Dalbandin. The shortest route, the Gwadar-Gabd corridor, reduces travel time to the Iranian border to between two and three hours, compared with the 16 to 18 hours it takes from Karachi – Pakistan's biggest port – to the Iranian border. Economic Impact of the Blockade The current US-Iran war began on February 28, when US and Israeli forces launched attacks on Iran. In the weeks that followed, Iran restricted commercial navigation through the Strait of Hormuz, the narrow waterway through which roughly a fifth of the world's oil and gas passes during peacetime, disrupting one of the most critical arteries of global trade. More than 3,000 containers destined for Iran have been stuck at Karachi port for several days, with vessels unable to collect the cargo. War-risk insurance premiums have surged from about 0.12% of a vessel's value before the conflict to roughly 5%, making shipping to the region too expensive for many operators. Shifting Regional Dynamics The corridor also signals a shift away from Afghanistan, whose relations with Pakistan have deteriorated sharply. The two sides engaged in clashes in October 2025 and again in February and March this year, with skirmishes continuing along the northwestern and southwestern borders. The Torkham and Chaman crossings have ceased to function as reliable commercial routes since tensions escalated, limiting Pakistan's overland access to Central Asian markets. “This is a paradigmatic shift. Pakistan's relations with the Afghan Taliban, the de facto rulers in Kabul, have no reset switch,” Iftikhar Firdous, cofounder of The Khorasan Diary, told Al Jazeera. Future Outlook The transit order appears to be a direct economic response to the impasse between the US and Iran. Pakistan brokered a ceasefire on April 8 and hosted the first round of direct US-Iran talks on April 11, in Islamabad. The negotiations lasted nearly a day but ended without a deal. Iran has ruled out direct negotiations with Washington while the blockade remains in place, though Araghchi told Pakistani officials that Tehran would continue engaging with Islamabad's mediation efforts “until a result is achieved”.

Houston survived a second‑straight elimination threat on April 30, 2026, beating the Los Angeles Lakers 99‑93 in Game 5 of the first‑round Western Conference series and forcing a Game 6.The Rockets’ Game‑5 Victory Keeps Their Playoff Hopes AliveAfter falling into a 3‑0 hole, the Rockets rallied behind a collective effort. Jabari Smith Jr. led with 22 points and seven rebounds, while Tari Eason added 18 points. Bench guard Austin Reaves, returning from an oblique injury, contributed 22 points off the bench. Alperen Şengün posted a near‑triple‑double with 14 points, nine rebounds and eight assists.Final score: Rockets 99, Lakers 93Series standing: Lakers lead 3‑2Key contributors: Smith Jr. (22), Reaves (22), Şengün (14‑9‑8)Defensive highlight: Rockets forced five Lakers turnovers in Q2Stat Sheet: Scoring, Rebounds, and Turnovers Highlight the UpsetThe Rockets out‑shot the Lakers 45‑38 overall and were especially efficient from beyond the arc in the second quarter (6‑12). Deandre Ayton recorded a double‑double for Los Angeles with 18 points and 17 rebounds, but the Lakers shot just 31% from the field.Three‑point shooting: Rockets 6‑12 (Q2), Lakers 4‑15 (game)Turnovers: Rockets 9, Lakers 13Free throws: Rockets 12‑12, Lakers 9‑12Bench scoring: Rockets 28 points, Lakers 12 pointsWhat This Win Means for the Western Conference LandscapeWhile no team has ever overturned a 3‑0 deficit, the Rockets’ resilience narrows the gap and puts pressure on a Lakers squad missing Luka Dončić (hamstring) and dealing with an inconsistent supporting cast. The victory also showcases the depth of Houston’s young core, suggesting they could become a dark‑horse contender if they sustain the momentum.Looking Ahead: Can Houston Complete the Comeback?Game 6 in Houston will test whether the Rockets can maintain their defensive intensity and continue to distribute scoring across the roster. If they win, the series heads to a decisive Game 7, where experience versus youth will be the defining factor. Analysts predict a tightly contested finale, with the Lakers’ star power needing to overcome fatigue and the Rockets’ growing confidence.

The Champions League Rights Auction Disney+ has secured live rights for men’s Champions League matches for the first time, with Uefa attracting a new buyer in the auction of broadcast packages for its flagship club competition. Disney has been named as the preferred bidder in several European countries, one of which is understood to be Sweden, in the auction of 19 TV markets for the 2027-31 cycle that concluded this week. Disney's Growing Interest in Football Rights Disney’s success is significant for the industry because it will be the first time the US company has bought Champions League rights and demonstrates the widening appeal of the competition to broadcasters and streamers. Disney’s interest in football rights has been building for some time, and is likely to grow. The company holds exclusive pan-European rights for the women’s Champions League until 2030 and Europa League and Conference League rights in Sweden and Denmark. The Financial Impact of Champions League Rights Uefa and UC3 last year secured increases of between 20% and 30% on their existing deals in the auction for the biggest five European markets of the UK, Spain, Germany, Italy and France, and are understood to have achieved further double-digit growth in the current round of sales. Uefa is projecting that the total value of its TV rights will exceed €5bn (£4.3bn) a year when the tenders are concluded, and as the Guardian reported this month it also expects to bring in more than €1bn annually through commercial deals. The Future of Sports Broadcasting This outcome will be welcomed by the clubs and domestic leagues because it demonstrates the increasing demand for football rights and will not divert resources from major rights holders such as Sky Sports, TNT Sports or Dazn. The recent auction was for Champions League rights in Austria, Belgium, Brazil, Bulgaria, Canada, Central America, Czechia, Denmark, Finland, Mexico, Norway, Poland, Portugal, the Republic of Ireland, Romania, Slovakia, South America, Sweden, and Switzerland.

Trump Urges Tehran to Surrender as Day 62 UnfoldsDonald Trump declared the U.S. blockade of Iranian ports a success and told Iran to “just give up”.Iranian Parliament Speaker Mohammad Bagher Ghalibaf dismissed the blockade’s impact, saying no oil wells have exploded and storage is not full.U.S. officials, including Treasury Secretary Scott Bessent, face criticism for “junk advice” on the policy.Escalating Standoff Over the Strait of HormuzThe blockade aims to force Iran’s oil storage to capacity, potentially halting production; analysts estimate current storage covers only ~20 days of output.Russian President Vladimir Putin warned Donald Trump not to resume attacks on Iran, calling the cease‑fire extension “the right one”.Key negotiation dead‑locks remain: Iran’s nuclear programme, $20 bn of frozen assets, and Tehran’s demand for $270 bn in war reparations.Oil Prices Surge and War Costs Climb Above $25 bnBrent crude jumped above $119 a barrel, WTI above $105, pushing global oil to >$120 per barrel.U.S. Defense Secretary Pete Hegseth estimated the war’s cost at “less than $25 bn” after 60 days.Washington seized nearly $500 m in Iranian crypto assets under “Operation Economic Fury”.Global Economic Ripple Effects and Regional TensionsOPEC entered “crisis mode”; the UAE plans to exit the group amid the energy shock.Asia‑Pacific economies face higher inflation as fuel and food prices rise; the Asian Development Bank cut growth forecasts.Bahrain’s revocation of citizenship for 69 individuals sparked Iranian condemnation, adding diplomatic strain in the Gulf.What the Next Weeks May Hold for the Iran ConflictAnalysts expect a gradual tightening of the blockade, with a possible acceleration in May if storage fills.U.S. officials are preparing for a “long blockade” to pressure Tehran into a non‑nuclear deal.Potential diplomatic pathways include renewed U.S.–Iran talks, but success hinges on resolving nuclear and reparations disputes.

Lancashire County Cricket Club has become the unwitting poster child for the ECB’s experimental injury‑replacement system introduced for the 2026 County Championship. With multiple denied subs and a pay‑wall looming over Old Trafford’s live stream, the club’s recent defeats highlight growing pains in the new rule. The New Injury‑Replacement Trial Hits Lancashire The ECB now permits teams to replace a player mid‑match for injury, illness or “significant life events”, subject to referee approval and medical documentation. There is no cap on the number of changes and the replacement must be “like for like”. Lancashire’s attempts to bring in Tom Bailey for Ajeet Singh Dale, and later George Bell for Arav Shetty, were rejected because referees judged the substitutes not sufficiently comparable. Numbers So Far: 16 Replacements in 29 Matches 16 injury/illness replacements recorded across the first 29 fixtures. +1 for concussion, bringing the total to 17 changes. England’s eight‑day stand‑down rule contrasts with Australia’s twelve‑day rule. Compared with Australia’s seven changes in 31 games, England’s rate is more than double. Why the Rules Are Disrupting County Strategies Referees are now making subjective judgments about experience, age and past performance, effectively second‑guessing selectors. Lancashire’s loss to Durham, where they could not field a frontline spinner, illustrates how the “like‑for like” clause can strip a side of balance, forcing seamers to bowl off‑breaks and weakening the attack on deteriorating pitches. Coaches such as Russell Domingo have joked about exploiting loopholes, underscoring concerns that the system could be gamed. What’s Next for Substitutes in English Cricket? The ECB has stressed the trial is “very much a trial” and mid‑season tweaks are possible. Expected outcomes include clearer definitions of “like for like”, possible caps on the number of changes, and alignment with international standards. If the experiment proves disruptive, the board may revert to stricter limits before considering similar rules for Test cricket.

The Legacy of All-English European Semi-Finals European football has witnessed numerous thrilling encounters between English clubs, with several all-English semi-finals standing out in history. These matches not only showcased exceptional skill and sportsmanship but also intensified rivalries that continue to influence the football landscape. Liverpool v Leeds (aggregate 0-1), Inter-City Fairs Cup 1970-71 In one of the earliest examples, Liverpool faced Leeds United in the Inter-City Fairs Cup. Billy Bremner's goal in the first leg proved decisive, securing a 0-1 aggregate victory for Leeds. This match was part of a heated rivalry between the clubs under the management of Bill Shankly and Don Revie. Chelsea v Manchester City (agg 2-0), Cup Winners' Cup 1970-71 Chelsea and Manchester City clashed in the Cup Winners' Cup, with Chelsea advancing to the final after a 2-0 aggregate win. Derek Smethurst's fine finish in the first leg and Ron Healey's error in the second leg sealed the victory for Chelsea. Liverpool v Tottenham (agg 2-2, Liverpool win on away goals), UEFA Cup 1972-73 The battle between Liverpool's Bill Shankly and Tottenham's Brian Nicholson ended with Liverpool progressing on away goals after a 2-2 aggregate draw. Steve Heighway's goal in the second leg proved crucial in securing Liverpool's place in the next round. Chelsea v Liverpool (agg 0-1), Champions League 2004-05 The 'ghost goal' by Luis García remains a contentious moment in Champions League history. Despite controversy, Liverpool's 1-0 aggregate win over Chelsea propelled them forward, with Anfield's electric atmosphere playing a significant role. Chelsea v Liverpool (agg 1-1, pen 1-4), Champions League 2006-07 Two years later, Chelsea and Liverpool were again embroiled in a dramatic semi-final. The match ended in a penalty shootout, with Liverpool emerging victorious after Pepe Reina saved crucial penalties. Liverpool v Chelsea (agg 3-4, aet), Champions League 2007-08 In another chapter of their rivalry, Chelsea finally gained the upper hand against Liverpool, winning 4-3 on aggregate after extra time. Didier Drogba's performance was pivotal in securing Chelsea's progression. Manchester United v Arsenal (agg 4-1), Champions League 2008-09 Manchester United dominated Arsenal in their semi-final encounter, securing a 4-1 aggregate victory. This win underscored Manchester United's strength in European competitions during that period. These historic semi-finals have contributed to the rich tapestry of English football rivalries, showcasing the competitive spirit and skill that define the sport.

The Controversial Instagram EndorsementIn early April, John Terry liked an Instagram post by former MP Rupert Lowe that urged a ban on foreign‑born benefit claimants and the deportation of “migrants who are incapable of financially supporting themselves”. Terry responded with a simple “100% yes”, prompting an immediate, scathing reaction from former teammate Denis Wise, who replied “200%”.Political Fallout and Public ReactionThe endorsement reignited accusations that Terry has long harboured far‑right sympathies, echoing earlier instances where he praised Lowe’s anti‑immigration pamphlet “Mass Deportations”. Critics argue the former captain is normalising extremist rhetoric that was once considered beyond the pale in mainstream sport.Terry’s Coaching Ambitions Amidst the StormWhile the controversy rages, Terry continues to chase a managerial role at Chelsea FC. After being passed over for the head‑coach vacancy in January, he remains on a consultancy contract, mentoring academy sides two days a month. The club’s reluctance to appoint him has been cited as a possible factor in his turn to high‑visibility political commentary.Broader Trend of Radicalisation in Retired FootballersMatt Le Tissier resurfaced in Southampton’s advisory board after promoting conspiracy theories about Ukraine.Rickie Lambert and Joey Barton have also embraced fringe narratives on social media.The pattern suggests a post‑retirement vacuum where former players seek relevance through provocative platforms.What Lies Ahead for Terry and the SportIf the backlash persists, Terry may pivot further into media work, podcasts, and right‑wing advocacy, potentially positioning himself for a future parliamentary candidacy. For football, the challenge will be balancing freedom of expression with safeguarding the sport’s inclusive image, especially as clubs grapple with the reputational risk of employing figures linked to extremist discourse.

Iranian Football Delegation Denied Entry and Forced to Return to TurkeyAn Iranian Football Federation team headed to the FIFA Congress in Vancouver was sent back at Toronto’s Pearson airport this week. Delegates Mehdi Taj (president), Hedayat Mombeni (secretary‑general) and Hamed Momeni (deputy secretary‑general) cited "unacceptable behaviour of immigration officials" as the reason for their immediate departure.Visa Revocation Tied to Canada’s IRGC Terrorist DesignationCanada listed the Islamic Revolutionary Guard Corps (IRGC) as a terrorist organization in 2024. Officials indicated that individuals linked to the IRGC are inadmissible, and the Iranian delegation’s visas were reportedly revoked on that basis. Canadian Foreign Affairs Minister Anita Anand described the denial as “unintentional” while acknowledging a revocation had occurred.Scale of the FIFA Gathering and World Cup Context211 member associations are slated to attend the pre‑World Cup FIFA Congress.The 2026 World Cup will feature a historic 48‑team format co‑hosted by Canada, the United States and Mexico.The congress is scheduled for Thursday, 2026‑05‑01, less than two months before the tournament kickoff.Implications for Iran’s World Cup Participation and Diplomatic RelationsThe incident underscores the practical hurdles Iran faces in traveling to a tournament hosted by three North‑American nations. While FIFA has affirmed that matches will proceed as planned, the delegation’s exclusion raises doubts about the freedom of movement for Iranian players, officials, and supporters during the event. It also adds diplomatic strain between Tehran and Ottawa, already tense after the IRGC designation.Looking Ahead: Potential Outcomes for Iranian Football and Future FIFA EngagementsFIFA president Gianni Infantino has offered to meet the Iranian officials at the organization’s headquarters, signaling a willingness to mitigate the fallout. However, unless Canada revises its immigration stance, future Iranian delegations may encounter similar barriers, potentially prompting Iran to seek diplomatic channels or legal challenges to secure entry for future tournaments.