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An Iranian missile has struck central Tel Aviv, causing widespread damage to buildings and vehicles, and injuring at least six people. The attack has led to a significant escalation of tensions in the region, with Israeli Prime Minister Benjamin Netanyahu vowing to continue striking Tehran and Lebanon.“There’s more to come,” Netanyahu said in remarks that appeared to corroborate those of three Israeli officials who told Reuters they thought it was improbable that Iran would accept US demands in any new round of negotiations. This development has dimmed hopes of de-escalation after US President Donald Trump played up the chances of a deal to end the conflict.In a statement released on Tuesday, Iran’s Islamic Revolutionary Guard Corps said it would launch heavy missile and drone attacks at Israeli troops in northern Israel and the area near Gaza “without restraint” unless Israel ceased attacks in Lebanon and Palestine. The threat has raised concerns about the potential for further escalation in the region.Police said an Iranian munition carrying a substantial explosive payload struck the central city, causing widespread damage to buildings and vehicles. At least six people were lightly injured. Several buildings were damaged across Tel Aviv, with emergency services reporting casualties at one of the impact sites. One building and the adjacent road were heavily affected, with cars set ablaze.Israel’s health ministry reports 4,829 injured people have been brought to hospitals since the onset of the war. Of those people, 111 remain in hospital and 12 are in a serious condition. The strikes were the latest in a cycle of retaliation after Israeli operations announced on Monday.About 40 minutes after Trump said he would delay action against Iran’s power infrastructure, Israel said on X that it had “just begun another wave of strikes targeting infrastructure of the Iranian terror regime across Tehran”. The Israel Defense Forces said energy facilities would be spared, suggesting that Israel may be aligning with Washington in suspending attacks on Iranian power plants and related sites.The US-based Human Rights Activists’ News Agency said in the previous 24 hours it had recorded at least 206 attacks across 15 provinces in Iran, resulting in at least four casualties (killed and injured, both civilian and military). At least six people were killed in strikes on homes in the city of Tabriz, according to Iran’s Fars news agency.Since US-Israeli bombs started falling on Iran, estimates of total deaths (military and civilian) in the country have exceeded 1,500, with some rights groups reporting figures as high as 3,230 as of 21 March. The escalation has also spilled beyond Israel, with Iranian strikes extending into Gulf states.

The UK's manufacturing sector has been hit by the sharpest rise in cost inflation since Black Wednesday in 1992, as the conflict in the Middle East drives up oil prices and disrupts supply chains. According to the Purchasing Managers' Index (PMI), cost inflation in manufacturing jumped to its highest level since October 2022, marking the largest month-on-month change since 1992.The rapid increases in costs mainly relate to fuel, transportation, and energy-intensive raw materials. The composite PMI index, covering services and manufacturing, stood at 51, suggesting the economy is still expanding, but at a sharply slower pace than the 53.7 seen in February.Chris Williamson, chief business economist at S&P; Global Market Intelligence, said: "Output growth across manufacturing and services has slowed to a crawl as companies blamed lost business directly on the events in the Middle East, whether through heightened risk aversion among customers, surging price pressures, higher interest rates, or via travel and supply chain disruptions."The CBI's survey of the retail sector also showed the fastest annual decline in sales volumes since April 2020, with the balance of retailers reporting rising sales at -52% in March, down from -43% in February.Martin Sartorius, lead economist at the CBI, said: "Retailers report that weak economic conditions continue to weigh on household spending, with subdued activity also evident across the broader distribution sector."Emily Sawicz, a director and industrials senior analyst at RSM UK, said: "Despite some resilience, geopolitical tensions remain a key concern for UK manufacturers – underscoring that conditions remain highly uncertain. The recovery many hoped to see take hold in 2026 now appears likely to be delayed at best, as rising energy costs and persistent inflation risks threaten to slow momentum."

The UK government has rejected a call from the Offshore Energies UK trade body to boost North Sea oil and gas production, despite warnings that the UK will become increasingly reliant on imports at a time of rising global instability.The industry group has urged the government to take action to slow the decline of the North Sea as a provider of energy, citing concerns that consumers will be left more exposed to global volatility and higher emissions if domestic production is not increased.The warning comes as the war in the Middle East has triggered the biggest oil and gas supply shock in the history of the market, causing UK gas prices to more than double in under a month.A government spokesperson said that issuing new licences to explore new fields cannot guarantee energy security and will not reduce bills, adding that the only way to truly protect against price spikes is to get off the rollercoaster of fossil fuel markets.The decline of the North Sea oil and gas basin means that the UK's reliance on gas imports is likely to increase sharply from about 14% last year to more than a quarter of its gas supply by 2030, and almost half by 2035.David Whitehouse, the chief executive of Offshore Energies UK, argued that energy security means backing homegrown oil and gas alongside renewables, and that a stable new tax regime for the industry is essential to reduce reliance on volatile imports and protect skilled jobs.

English and Welsh winemakers have experienced a significant surge in wine production in 2025, with 16.5m bottles produced across the UK, representing a 55% increase from the previous year. This growth is attributed to the hot, dry summer and an increase in vineyard plantings, resulting in the third-largest UK harvest. The 124,377 hectolitres of wine produced in 2025 is still below the 21.6m bottles produced in 2023, which was considered a bumper year. However, the industry has seen a substantial recovery from 2024, when production halved to 10.7m bottles due to high rainfall and disease in the grape crop. The 2025 harvest saw a notable increase in white wine production, which rose by 131% compared to 2024. Nicola Bates, chief executive of WineGB, expressed optimism about the quality and scale of the 2025 vintage, highlighting the skill and hard work of viticulturalists and winemakers. The growth of the industry is reflected in the 4% increase in vineyards registered with the Food Standards Agency (FSA) to 1,158, with the majority being commercial operators. The UK wine sector now employs over 10,000 people and has a value of £14bn. The industry has seen a 3% increase in vine plantings in 2025, covering an area of 4,357 hectares (10,700 acres).

The United Nations has recorded 143 deaths in an air strike on a drug rehabilitation centre in Kabul, significantly lower than the figure offered by Afghanistan's Taliban government.The attack on Kabul's Omar Addiction Treatment Hospital on Monday night has sharpened a bitter dispute between Pakistan and Afghanistan, with the Taliban putting the casualties at more than 400 people killed and about 265 wounded.The UN Assistance Mission in Afghanistan provided its figure to the Reuters news agency on Wednesday. The gap between the two counts underscores the difficulty of verifying casualty figures in the conflict as competing claims frequently come from Kabul and Islamabad.Afghanistan's Taliban administration has blamed Pakistan for the attack on the drug rehabilitation centre, a 2,000-bed facility, and Pakistan has denied carrying out the strike. Hamdullah Fitrat, a deputy spokesman for the Taliban administration, said the strike hit the hospital, destroying large sections of the building and triggering fires that rescue teams worked through the night to contain.Afghan government spokesperson Zabihullah Mujahid accused Pakistan of deliberately hitting civilian infrastructure and called the assault a “crime against humanity”. Mujahid said those killed and wounded were patients undergoing addiction treatment at the time of the strike.Pakistan's information minister, Attaullah Tarar, denied the allegation, insisting his country “only targeted terrorist infrastructure and military locations”. The strike is the latest in a widening confrontation between the two neighbours, who have engaged in repeated cross-border clashes.At the heart of the dispute is a long-running Pakistani accusation that the Taliban government shelters the Pakistan Taliban, known as Tehrik-i-Taliban Pakistan, as well as outlawed Baloch separatist groups responsible for attacks on Pakistani soil. Kabul has consistently denied providing sanctuary to the groups.

A cooking gas crisis in India has forced a mass exodus of workers from the country's vital textile industry, according to reports. The shortage of LPG (liquefied petroleum gas) has created significant disruptions to both household needs and industrial operations.The textile sector, which employs millions of workers across India, has been particularly hard hit as workers have been compelled to leave their jobs and return to rural areas in search of alternative cooking fuel sources. This mass migration represents a serious challenge to India's manufacturing economy and could have long-term implications for the country's industrial output.While the full extent of the crisis remains unclear, industry experts warn that the prolonged energy shortage could lead to further production shutdowns and economic instability in regions heavily dependent on textile manufacturing.

The conflict between Iran and Israel has taken a significant turn, with oil prices skyrocketing to unprecedented levels. Analysts are now warning that prices could reach $150 or even $200 per barrel, a scenario that was previously considered far-fetched.The global benchmark, Brent crude, has hit nearly $120 per barrel and has remained above $100 since March 13. The recent Israeli strike on Iran's South Pars gasfield and subsequent Iranian attacks on oil and gas facilities in Qatar, Saudi Arabia, and the United Arab Emirates have further pushed crude prices up to over $108 per barrel.The Strait of Hormuz, which accounts for about one-fifth of global oil supplies, has been effectively closed since Iran declared it shut early in the conflict. Only a handful of ships, mostly Indian, Pakistani, Turkish, and Chinese-flagged vessels, have been allowed to pass through in recent days.Market watchers agree that prices have room to move much higher if the Strait of Hormuz remains closed. Vandana Hari, founder of Vanda Insights, notes that benchmark Middle Eastern crudes have already crossed the $150 threshold, making $200 a possibility.The International Monetary Fund estimates that every 10% rise in oil prices would correspond with a 0.4% increase in global inflation and a 0.15% reduction in economic growth. Oil prices at $150 or higher would weigh heavily on the global economy.Adi Imsirovic, an energy expert at the University of Oxford, warns that oil at $200 per barrel would be a major handbrake to the world economy, impacting inflation, growth, employment, and potentially causing shortages of fuel and materials.

US President Donald Trump has requested a delay in his highly anticipated trip to China, initially scheduled for March 31-April 2, by about a month. The decision comes amid the ongoing US-Israeli war on Iran, which has resulted in significant escalation of tensions in the Middle East. “We've requested that we delay it a month or so,” Trump told reporters at the White House on Monday. “There's no tricks to it either. It's very simple. We've got a war going on. I think it's important that I be here.” The delay underscores how the Iran war has upended Trump's foreign policy agenda and risks magnifying tensions between Washington and Beijing. The war has joined trade and Taiwan as among the spectrum of issues separating the world's two biggest economies. Trump's request has been largely rebuffed so far, with China not directly responding to his request to help unblock the Strait of Hormuz, which Iran says is closed to US and Israeli-linked vessels. The Strait of Hormuz is a critical waterway through which one-fifth of the world's oil usually transits. US Secretary of the Treasury Scott Bessent said earlier on Monday that Trump may need to delay the trip due to coordinating the war effort, not because of China's unresponsiveness to Trump's request or because of any trade disagreements. “The president wants to remain in DC to coordinate the war effort. Traveling abroad at a time like this may not be optimal,” Bessent said. In related trade negotiations, the Chinese showed openness to potential additional purchases of US agricultural goods, including poultry, beef, and non-soya bean row crops, during talks with Chinese Vice Premier He Lifeng in Paris.

US lawmakers, including Senator Chris Murphy and Representative Greg Casar, are taking steps to regulate prediction markets by introducing the Banning Event Trading on Sensitive Operations and Federal Functions (BETS OFF) Act. This legislation seeks to prohibit wagers on sensitive events such as government actions, terrorism, war, assassination, and events where an individual knows or controls the outcome. The proposed bill comes in response to concerns that betting platforms like Kalshi and Polymarket have allowed users to profit from geopolitical conflicts, including the US and Israel's joint strikes against Iran and the abduction of Venezuelan President Nicolas Maduro. Critics argue that these platforms enable individuals with insider knowledge to influence government decisions and profit from them. Murphy emphasized that the legislation aims to prevent the monetization of sensitive events, stating, "What happens to us spiritually when every moral question in this country becomes a market?" He added that certain matters should not be influenced by the potential for profit. The lawmakers cited examples of significant profits made by users on Polymarket, including a $500,000 profit from a bet on Iran's supreme leader being out of power hours before a strike. They suggested that such trades may have been made by individuals with insider knowledge from within the White House or close to the administration. The BETS OFF Act is part of a broader effort to regulate the prediction market industry. Other proposed legislation includes measures to establish federal consumer protections, ban elected officials from profiting from prediction markets, and impose age verification for users.