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Robert F Kennedy Jr, the US health secretary, has unveiled a chaotic and unpredictable agenda for public health policy under his 'Make America Healthy Again' (Maha) initiative. His approach tends to favor personal choice and autonomy over large-scale, mandatory public health interventions, such as childhood vaccine requirements.The Maha agenda has raised concerns over the potential risks associated with injectable peptide drugs. Mr. Kennedy plans to open up the sale of 'about 14' of these drugs to the public, despite the US Food and Drug Administration (FDA) restricting 17 peptides in 2023 due to 'potential significant safety risks'. None of these peptides have been proven to be safe or effective for human use.The peptides in question are often promoted for biological enhancement, such as increasing muscle mass or cognitive benefits, but the evidence for these effects in humans is thin. Reports of people self-administering peptide therapies, usually bought from China 'for research use only', are widespread, particularly in Silicon Valley.The Maha project wants to make the grey market the only market, effectively sanctioning mass public use of unproven treatments. Peptides are clearly drugs and shouldn’t be allowed for widespread use without rigorous clinical trials. Opening loopholes for sale would undermine the precautionary principle that has successfully led public health policy for generations.It is also worth noting that other governments are unlikely to be as cavalier as Mr. Kennedy about peptides. However, people everywhere will continue to call for more personal choice and more bodily autonomy, and those conversations are important. The case for safety, proof, and regulation must be made to ensure that public health policy prioritizes the well-being of individuals.

Véron Mosengo-Omba, the general secretary of the Confederation of African Football (Caf), has resigned after repeated calls for his removal and at a turbulent time for African football. His departure comes amid a crisis of confidence in the organisation's leadership, largely due to the decision to strip Senegal of the Africa Cup of Nations (Afcon) title and allegations of corruption.Mosengo-Omba, 66, said he was retiring but his exit follows a period of intense criticism of his tenure, including accusations of creating a toxic workplace culture at Caf. An investigation into staff complaints had previously cleared him of wrongdoing. He is of Congolese origin but a Swiss citizen and a former Fifa employee.In a statement, Mosengo-Omba said: 'After over 30 years of an international professional career dedicated to promoting an ideal form of football that brings people together, educates, and creates opportunities for hope, I have decided to step down from my position as secretary general of Caf to devote myself to more personal projects.'He expressed gratitude to Caf's president, Dr Patrice Motsepe, and his teams, and hoped that the progress made during his tenure would 'last and be sustained'. Mosengo-Omba is expected to run for the post of president of the Democratic Republic of Congo's football federation.The controversy surrounding Caf's leadership has led to Senegal's government calling for an international investigation into the organisation. Caf's competitions director, Samson Adamu, will take over as acting general secretary.Earlier this month, Motsepe admitted that Caf was struggling with questions over its integrity. The organisation is set to expand the Africa Cup of Nations to 28 teams from 24, with plans to introduce a Nations League annually from 2029.

The concept of luck has long been shrouded in mystery, often attributed to chance or fate. However, behavioural neuroscience has made significant strides in uncovering the underlying mechanisms that govern luck. According to research, luck is not just a roll of the dice, but rather a complex interplay of brain chemistry and behaviour that can be influenced and cultivated.The neuroscience behind luck reveals that it operates through identifiable patterns of brain chemistry and behaviour. Studies have shown that the consistently lucky are not blessed by fate, but rather, they possess a unique set of habits and characteristics that enable them to capitalize on opportunities and navigate challenges more effectively. Brain imaging techniques have even identified specific regions of the brain that are activated when individuals perceive themselves as lucky, shifting their perception from threat-detection mode to opportunity-recognition mode.Serotonin production, regulated by morning sunlight, tryptophan-rich foods, and a regular sleep-wake cycle, plays a critical role in determining one's luck. Individuals who prioritize these factors are more likely to experience a boost in serotonin levels, which in turn, enhances their mood, social confidence, and resilience. Conversely, those who lead erratic lifestyles and neglect these factors may find themselves chronically sleep-deprived and less likely to encounter fortunate events.Lucky individuals also tend to possess a clear awareness of their interests and passions, which guides their decision-making and behaviour. By following their 'fascination compass', they are more likely to stumble upon opportunities and experiences that align with their values and goals. Novelty-seeking and a willingness to take calculated risks also characterize lucky individuals, as they understand that each small departure from routine can be a ticket to new experiences and encounters.Generosity and a willingness to help others without expectation of return are also key characteristics of lucky individuals. Brain imaging studies have shown that acts of genuine generosity activate the brain's deepest reward centre, releasing feel-good chemicals that reinforce positive behaviours and build social capital. By investing in others and cultivating meaningful relationships, lucky individuals create a network of opportunities and support that can help them navigate life's challenges.In conclusion, luck is not just a matter of chance, but rather a complex interplay of brain chemistry, behaviour, and habit. By understanding the underlying mechanisms that govern luck and incorporating these insights into daily life, individuals can increase their chances of experiencing fortunate events and leading a more fulfilling life.

The conflict in the Middle East has taken a dramatic turn as Yemen's Iran-backed Houthis launched a second wave of attacks on Israel since joining the conflict on Saturday. The Houthis have vowed to continue their military operations in the coming days until Israel "ceases its attacks and aggression".In a significant escalation, two powerful explosions shook northern Tehran early on Sunday, with air defenses operating in the Iranian capital. The blasts occurred around 7:20 am, but it was not immediately clear what was targeted.Meanwhile, the US is reportedly preparing plans for ground operations in Iran, with the Trump administration having already deployed US Marines to the Middle East. The Pentagon is considering weeks of ground operations in Iran, potentially including raids on Kharg Island and coastal sites near the Strait of Hormuz.The entry of the Houthis into the conflict poses a direct threat to the Bab al-Mandab strait at the southern end of the Red Sea, a critical choke point in the supply chain of energy supplies and other trade in and out of the Middle East. A shutdown of the Bab al-Mandab, located between Yemen and the Horn of Africa, would amplify the already grave impact of the war on the global economy and could also reignite a Saudi-Yemen conflict.Exiled Iranian Crown Prince Reza Pahlavi has told one of the US's biggest annual gatherings of conservatives that he is ready to lead a new Iranian government and would call on the country's citizens to rise up when the "right moment arrives".Iran's Revolutionary Guard has threatened to target US universities in the Middle East after saying US-Israeli strikes had deliberately targeted two Iranian universities.

The live updates page for Iran war news has been closed, but readers can continue to follow the latest developments here.

Iranian politicians are pushing for the country to exit the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) as the conflict with the US and Israel escalates. The country's national security commission spokesman, Ebrahim Rezaei, stated that remaining a signatory to the treaty has been 'meaningless' and provided no benefits to Iran.Malek Shariati, a representative from Tehran, has introduced legislation to withdraw Iran from the NPT, revoke a law linked to the 2015 nuclear deal, and support a new international treaty with aligned countries to develop peaceful nuclear technologies. The proposed law must be approved by the parliament and the Guardian Council before implementation.The move comes as the US and Israel have ramped up their attacks on Iranian nuclear sites, steel factories, and a university. Recent air strikes have targeted key infrastructure, including a yellowcake facility in Yazd and the Khondab Heavy Water Complex near Arak. The International Atomic Energy Agency (IAEA) has warned about the potential for a major radiological incident.Iranian authorities have accused the IAEA of taking a politicized stance and being complicit in attacks against Iranian nuclear sites. IAEA Director Rafael Grossi has been criticized by Iranian officials, with one adviser to the Supreme Leader labeling him a 'partner in crime.'The conflict has also had significant economic impacts, with thousands of jobs at risk due to damage to Iran's steel giants. The country's economy is struggling with an energy crisis and inflation rates of about 70 percent. The internet has been blocked for a month, limiting the flow of information to state-run outlets.

The US Secretary of State has made a statement indicating that the ongoing war could conclude in 'weeks, not months', offering a glimmer of hope for a swift resolution to the conflict. The Secretary's comments have garnered significant attention, as they suggest a potential shift in the dynamics of the war.While details about the Secretary's statement are limited, the prospect of a rapid conclusion to the conflict has sparked optimism among some observers. The possibility of a negotiated settlement or a significant escalation in diplomatic efforts has raised hopes that the war could be brought to an end sooner rather than later.However, it remains to be seen whether the Secretary's comments will translate into tangible progress in the conflict. The path to peace often proves complex and fraught with challenges, and it is unclear what specific steps will be taken to achieve a swift resolution.

Yemen's Houthi rebels have launched a barrage of ballistic missiles at Israel, marking their first such attack since the US-Israel war on Iran began. The assault was announced by Brigadier-General Yahya Saree, a military spokesman for the Houthis, on their Al-Masirah satellite television. The attack targeted what Saree described as 'sensitive Israeli military sites' in southern Israel. The Israeli military reported intercepting one of the missiles. This development comes as Iran and Hezbollah continue to fire on Israel, with sirens sounding around Beer Sheba and near Israel's main nuclear research centre. Saree stated that the strikes 'will continue until the declared objectives are achieved, as stated in the previous statement by the armed forces, and until the aggression against all fronts of the resistance ceases'. This escalation follows a vague statement by Saree on Friday signaling the rebels' intention to join the conflict. The Houthis, who have controlled Yemen's capital, Sanaa, since 2014, had previously stayed out of the US-Israel war. However, they have been involved in attacks on shipping vessels during the Israel-Hamas war, disrupting commercial transit in the Red Sea. Over 100 merchant vessels were attacked with missiles and drones, resulting in two ships sinking and four sailors killed between November 2023 and January 2025. Experts consider the Houthis' entry into the US-Israeli war on Iran as 'very significant'. Mohamad Elmasry, a professor of Media Studies at the Doha Institute for Graduate Studies, noted that if the Houthis were to shut down the Bab al-Mandab Strait, the Red Sea, and the Suez Canal, it would impact two major international shipping waterways, alongside the Strait of Hormuz. Al Jazeera's Nida Ibrahim reported from Ramallah that the opening of a new front in the war is likely to raise questions in Israel about 'the viability of the operations and the way the government is conducting its war'. She expects Israel to retaliate to this attack, as seen in previous instances when Yemen joined the battle.

Reports are emerging of multiple explosions occurring in the Iranian cities of Tehran and Isfahan. The incidents have resulted in a heightened state of alertness and concern among local authorities and residents. The source of the bombings and the extent of the damage remain unclear. However, eyewitnesses describe the scenes as chaotic, with emergency services quickly responding to the affected areas. Iran has been a focal point of geopolitical tensions in recent years, and these bombings are likely to exacerbate existing concerns about regional stability. As more information becomes available, it is expected that there will be a significant impact on international relations and security measures in the area.