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The Final Showdown: Teams and TacticsCrystal Palace and Rayo Vallecano meet in Leipzig for the 2026 Conference League final. For Palace, this is the curtain call for manager Oliver Glasner, who aims to secure his first piece of European silverware and finish his tenure with two trophies in south London.Crystal Palace: Henderson; Muñoz, Riad, Lacroix, Canvot, Mitchell; Wharton, Kamada; Pino, Sarr, Mateta.Rayo Vallecano: Batalla; Ratju, Lejeune, Ciss, Chavarría; López, Valentin, Palazón; Garcia, Alemao, De Frutos.The Stakes: A Guaranteed Europa League SpotThe winner secures an automatic berth in next season's Europa League. This is a massive prize for both teams: Rayo finished 8th in La Liga, while Palace finished 15th in the Premier League. Without this victory, neither club would have qualified for European competition next season.A Historic Opportunity for UnderdogsThis final represents a rarity in European football: a clash between two clubs not named Real Madrid, Atlético Madrid, Manchester City, or Arsenal. Palace's journey was unexpected, having been demoted from the Europa League due to multi-club ownership rulings, a decision that ultimately proved to be a "blessing in disguise."The Prediction: Palace's Edge in DepthDespite Rayo's impressive run through the semi-finals against RC Strasbourg, Crystal Palace enters as the slight favorites. Palace boasts a more experienced squad capable of handling the pressure of a final, particularly with their creative midfield options. Glasner's tactical discipline should see the Eagles edge out the Spanish side in a tight encounter.

The Stalemate in US-Iran Nuclear Deal Talks Despite suggestions that a deal between the United States and Iran may be close, officials from both countries have continued to issue conflicting statements, signalling an ongoing diplomatic impasse. Trump's Stance on Sanctions Relief Speaking at Wednesday’s cabinet meeting, US President Donald Trump said Iran would not receive any sanctions relief as a result of the negotiations, despite Iran’s demands otherwise. “We’re not talking about any easing of sanctions or giving money,” Trump said. Iran's Position on Enriched Uranium Earlier in the day, in an interview with PBS News, the US president also reiterated his claim that Iran would surrender its reserves of enriched uranium. “They’re going to give up their highly enriched uranium, not for sanctions relief. No, no, not at all,” Trump told PBS News. The Data Analysis: Economic Impact of the Conflict The war has failed to collapse Iran’s governing system, but it has sent energy prices soaring across the world and fuelled inflation in the US. The blockade of the Strait of Hormuz has led to a significant increase in energy prices. The conflict has resulted in hundreds of civilian casualties and the killing of Iran's Supreme Leader Ali Khamenei. The Impact Analysis: Regional and Global Consequences The ongoing conflict between the US and Iran has significant implications for the region and the world. The US and Israel launched a war against Iran on February 28 without direct provocation, killing the country’s Supreme Leader Ali Khamenei and several top officials, as well as hundreds of civilians. The Prediction: Future Outlook It remains unclear if either party has offered concessions to secure an agreement. Trump, for instance, told the cabinet meeting that he “wouldn’t be comfortable” with the prospect of Iran’s uranium being transferred to Russia or China, instead of the US.

On 15 May, **BioOrbit** launched its compact **Box‑E** payload aboard a **SpaceX** rocket, beginning a six‑week orbital trial to grow ultra‑pure protein crystals for self‑injectable cancer therapies. Box‑E’s Orbital Test: Microgravity Enables Ultra‑Pure Protein Crystals The microwave‑sized unit will float aboard the International Space Station, where microgravity eliminates the disruptive effects of Earth’s gravity on crystal formation. The resulting crystals are more stable, allowing drug formulations that are impossible to achieve on the ground. Mission duration: ~6 weeks in orbit Target output: thousands of litres of fluid per box per year Goal: Produce cancer‑drug crystals that can be stored in a fridge and self‑injected £9.8 Million Funding Round and UK Space Agency Contract Last month **BioOrbit** closed a **£9.8 million** Series A round led by **LocalGlobe** and **Breega**, earmarked for the orbital test and scaling of the hardware. Earlier in March the company secured a **£250,000** contract from the UK Space Agency to manufacture drugs in microgravity. Potential Disruption of Cancer Treatment Delivery Current immunotherapies such as Merck’s **Keytruda** require lengthy IV infusions in hospitals. By crystallising the active protein, **Box‑E** could enable high‑concentration, low‑viscosity formulations suitable for pen‑injectors, reducing treatment time from hours to minutes and extending shelf‑life. Roadmap to Commercialisation and Market Size **BioOrbit** projects that, if orbital tests succeed, multiple **Box‑E** units could be stacked to meet the demand of a blockbuster drug within a handful of boxes. The company estimates a market of **$22.7 trillion** for in‑space manufacturing across sectors, with pharmaceuticals a key segment. Clinical trials and regulatory approval are expected to take at least five years before the new formulations reach patients. Future Outlook for Space‑Based Pharma Beyond cancer, the crystallisation platform could be applied to the roughly 70 % of top‑selling drugs that are currently administered intravenously. Partnerships with major pharma groups are already being explored, and competitors such as **Varda Space Industries** are also pursuing in‑orbit drug processing, signaling a burgeoning industry.

The LeadJilly Cooper's novels have captivated readers with their blend of romance, humor, and social commentary. The Guardian has ranked her best books, providing insight into her writing style and popular themes. Exploring Jilly Cooper's NovelsCooper's works are known for their strong female characters, romantic storylines, and satirical portrayal of social classes. Her novels often explore themes of love, relationships, and personal growth. Classic Jilly Themes Underdogs triumph; dogs also triumph. Artistic people are naturally hornier; also, horn players. There's a white knight for even the unlikeliest damsel. Mothers and daughters in erotic contest. There's nothing more embarrassing than wanting to be posher than you are. The Books 10. Tackle! (2023)In the last of Jilly Cooper's Rutshire Chronicles, Rupert Campbell-Black, now 67, navigates life with his wife Taggie, who has cancer. The story follows their daughter Bianca's romance with a footballer and Rupert's attempts to keep them in the same postcode. 9. Appassionata (1996)This novel follows Marcus, Rupert's son, as he navigates his engagement to Abigail and his secret affair with a Russian ballet dancer. The book explores themes of love, identity, and social class. 8. Octavia (1977)Octavia is a rare example of a bad-girl heroine. Rich and selfish, she steals her friends' boyfriends until she meets her match in Gareth. The novel is a commentary on the conflict between independence and intimacy. 7. The Man Who Made Husbands Jealous (1993)This novel follows Lysander Hawkley, a difficult love interest, as he navigates his relationships with women. The story explores themes of love, sex, and relationships. 6. Class: A View from Middle England (1979)This nonfiction work explores the lives and mores of fictional characters, satirizing social classes. Cooper's eye for the vanities and delusions of the upper classes is particularly sharp. 5. Jump! (2010)In the ninth Rutshire novel, a familiar heroine navigates her flaws and finds love. The story is a classic example of Cooper's blend of romance and social commentary.

Deadly Train Bomb in Balochistan Kills DozensAt least 24 people were killed and more than 50 injured when a suicide car bomb detonated on a train carrying soldiers in Quetta, capital of the southwestern Pakistani province of Balochistan. The attack occurred during Pakistan's Prime Minister Shehbaz Sharif's four-day visit to China, just before his meeting with China's President Xi Jinping to mark 75 years of diplomatic ties between the two nations.Sunday's Devastating Attack on Military TrainAccording to reports from the scene, several houses and buildings adjacent to the railway line were severely damaged in the blast, which caused train carriages to overturn and catch fire. A state of emergency was declared at public hospitals in Quetta, with doctors and medical staff ordered to remain on duty. Footage shared online showed charred vehicles and train carriages lying on their sides, with thick plumes of black smoke rising into the sky.Pakistan's Prime Minister Sharif condemned the attack in a post on X, stating: "Such cowardly acts of terrorism cannot weaken the resolve of the people of Pakistan. We remain steadfast in our determination to eliminate terrorism in all its forms and manifestations."Escalating Violence: Statistics on Balochistan ConflictResearch from the Pakistan Institute for Peace Studies indicates Balochistan recorded at least 254 attacks in 2025 – roughly 26 percent more than in 2024. A December 2025 report by ACLED found that separatists had intensified attacks, with the number of attacks using improvised explosive devices (IEDs) and grenades growing by more than 65 percent in the first 11 months of 2025 compared to the same period in 2024.The Global Terrorism Index report for 2026 found increased Baloch armed group activity in Pakistan, with the BLA responsible for Pakistan's largest terror attack of 2025 – the hijacking of the Jaffar Express train in March, which resulted in six military personnel killed and hundreds of passengers taken hostage.Who Are the BLA and Major Baloch Armed Groups?The Balochistan Liberation Army (BLA), which has a suicide squad called the Majeed Brigade, is the largest of several ethnic separatist groups fighting the federal government. It says it is fighting for the independence of Balochistan, Pakistan's poorest region despite its wealth of natural resources. The BLA often targets infrastructure and security forces but has also struck in other areas, including Karachi.The BLA has deployed women suicide bombers and was designated a "foreign terrorist organisation" by the United States in August 2025. The group was also at the center of tit-for-tat strikes in 2024 between Iran and Pakistan, bringing the neighbors to the brink of war.The Baloch Cause: Resources and MarginalizationHome to about 15 million of Pakistan's roughly 240 million people, Balochistan is the country's poorest region despite its wealth of natural resources, including coal, gold, copper, and gas. These resources generate significant revenue for the federal government – unfairly, according to the BLA, which wants Balochistan's natural wealth to belong to its people.The province is home to one of Pakistan's major deep-sea ports at Gwadar, a crucial trade corridor for China's $65 billion investment in the China-Pakistan Economic Corridor (CPEC), a wing of President Xi Jinping's Belt and Road initiative. It also contains key mining projects, including Reko Diq, believed to be one of the world's largest gold and copper mines.Regional Stability and International Investment at RiskThe attack comes as Pakistan attempts to strengthen economic and security cooperation with China – something the BLA strongly opposes. The movement poses a challenge to Pakistan's efforts to retain Chinese and American investment, potentially revealing deeper instability in the region."The persistence of insurgency has had implications for Pakistan's wider political system," explained Yunas Samad, an emeritus professor of South Asian Studies. "Security concerns in Balochistan have increasingly shaped governance and political discourse, strengthening the role of the military and security establishment in national affairs and undermining the democratisation process."Internationally, the issue matters because Pakistan remains a nuclear-armed state of enormous strategic importance. Any significant escalation in internal instability in a country with nuclear capabilities inevitably attracts international concern.Rare-Earth Minerals and Geopolitical CompetitionAnother major issue is that geological assessments suggest Balochistan contains 12 of the 17 rare-earth minerals on the periodic table. Rare earths are critical minerals used to manufacture a vast array of modern items, including batteries, military hardware, smartphones, and semiconductors.Since the start of his second term, US President Donald Trump has pushed plans to diversify Washington's stockpile of critical minerals to reduce reliance on China, which currently dominates the supply and processing of the world's rare-earth minerals. In December 2025, the US announced a $1.25 billion investment in critical minerals mining at Reko Diq to drive "economic growth in Balochistan."Future Outlook for Balochistan's ConflictWhether the current surge in attacks constitutes an entirely "new phase" of the conflict remains unclear. However, it does appear to indicate a degree of resurgence in militant capability and confidence among sections of the Baloch insurgency."The fact that this latest incident nevertheless occurred may suggest that militant groups retain a significant operational capability despite security efforts," noted Samad. "Whether this constitutes an entirely 'new phase' is perhaps too strong a conclusion at present. However, it does appear to indicate a degree of resurgence in militant capability and confidence among sections of the Baloch insurgency."The Baloch separatist movement remains one of the major unresolved questions over Pakistan's statehood, serving as a constant reminder of the challenges the Pakistani state faces in maintaining unity and stability in the region.

The Final Countdown for Early Bird Tickets There are only 3 days left to save up to $410 on your ticket to TechCrunch Disrupt 2026. Early Bird pricing ends May 29 at 11:59 p.m. PT, and once the deadline passes, ticket prices increase. What to Expect at TechCrunch Disrupt 2026 From October 13–15 at Moscone West in San Francisco, TechCrunch Disrupt brings together 10,000+ founders, investors, operators, and innovators driving the future of technology. Founder Pass: Connect with investors, gain practical insights, and access the tools and relationships that help startups grow faster. Investor Pass: Meet emerging startups, discover new investment opportunities, and maximize every conversation with curated networking tools. The Importance of Securing Your Ticket Now Whether you’re raising capital, scouting investments, hiring talent, launching a startup, or building strategic partnerships, Disrupt is designed to put you in the middle of the conversations shaping what’s next. The countdown is on. Early Bird pricing disappears May 29 at 11:59 p.m. PT. Secure your ticket now and save up to $410 before rates increase.

The UFC Event on the White House Lawn Crews are erecting an octagon-shaped cage on the South Lawn of the White House that will host next month’s Ultimate Fighting Championship (UFC) bout, marking the nation’s 250th anniversary and President Donald Trump’s 80th birthday. Event Details and Construction Online renderings depict what the completed, wire-mesh-fence-ringed fight space is expected to look like before the June 14 event. It will be ringed by a red, white and blue stage under a towering arch featuring stars-and-stripes patterns and two large screens showing the action live. The cage and stage will themselves be surrounded by thousands of temporary seats, including ringside space for a full marching band that can set the entire scene to blaring music. Significance and Additional Events The project is part of a series of events celebrating the semiquincentennial of the Declaration of Independence’s signing on July 4, 1776. Other planned functions include an IndyCar race that will pass by the White House and the Great American State Fair taking place on the National Mall. Trump has said the finished UFC project will feature “a 5,000-seat arena right outside the front door of the White House”. Logistics and Ticket Demand Additional large screens broadcasting the fights will be set up in a park at the nearby Ellipse, and the UFC has said it plans to issue as many as 85,000 free tickets to accommodate spectators at both locations. “I have never seen anybody want anything so much as people want those tickets,” Trump said recently of demand to attend the UFC fight, adding, “That’s gonna be something.” Criticism and Other Projects The card has been panned by fans online as underwhelming, featuring just two championship fights. Brazil’s Alex Pereira will meet France’s Ciryl Gane for the interim UFC heavyweight title. Then, Spanish-Georgian lightweight champion Ilia Topuria takes on interim champ Justin Gaethje, one of just two Americans who currently hold even a share of the UFC’s 11 championship belts. The octagon and surrounding structures are the latest project in the White House building boom Trump is leading.

Lead The Oklahoma City Thunder rebounded from a shaky start to post a 127-114 win over the San Antonio Spurs, seizing a 3-2 series edge and moving within a single game of the NBA Finals. Thunder Surge in Q2 and Q3 to Secure 127-114 Victory After missing his first four shots and committing three turnovers in the opening quarter, Shai Gilgeous‑Alexander ignited the offense, scoring 12 points in the 40‑point second quarter and adding 11 in the third. Coach Mark Daigneault shuffled the lineup, inserting Jared McCain into the starting five, a move that paid off as the rookie delivered 20 points, most of them after halftime, and protected the ball with zero turnovers in the second half. The Thunder built an 11‑point halftime lead and extended it early in the third, never looking back. Statistical Breakdown: Scoring, Shooting, and Free Throws Final score: 127-114 (Thunder over Spurs) Series lead: Thunder up 3-2 in the Western Conference Finals Shai Gilgeous‑Alexander: 32 points, 9 assists, 7‑of‑19 shooting Jared McCain: 20 points (18 after halftime), 0 turnovers in the second half Chet Holmgren: 16 points, 11 rebounds Alex Caruso: 22 points, 6 assists, 3 steals Victor Wembanyama: 20 points, 6 rebounds, 4‑of‑15 shooting Free throws: Thunder 38, Spurs 32 What the Win Means for the Western Conference Finals The victory restores momentum to a Thunder squad that had dropped Game 4, showcasing depth beyond its star guard. With key contributors like Holmgren and Caruso delivering double‑digit scoring, Oklahoma City can absorb injuries to role players such as Jalen Williams and Ajay Mitchell. For the Spurs, the loss highlights a declining offensive output from Victor Wembanyama, who has struggled to convert shots and rebound at his early‑series pace, putting additional pressure on coach Mitch Johnson to find alternative scoring options. Path to the NBA Finals: What to Expect in Game 6 Game 6 in San Antonio will likely be a showdown between a resurging Thunder offense and a Spurs team forced to lean on Wembanyama’s interior dominance. If Oklahoma City maintains its aggressive perimeter defense and continues to exploit free‑throw opportunities, the Thunder could close the series. Conversely, a breakout offensive performance from Wembanyama—meeting his coach’s call for 15+ shots and 20+ points—could force a decisive Game 7 back in Oklahoma City.

The Lead: Fury-Joshua Showdown Takes ShapeTyson Fury has officially announced his return to boxing, scheduling a fight in Dublin on August 1, just one week after fellow former world heavyweight champion Anthony Joshua makes his comeback against Albanian opponent Kristian Prenga. The timing of these fights strongly suggests both boxers are preparing for their long-awaited 'Battle of Britain' showdown, which promoters have indicated could take place as early as November.The Event Details: Fight Cards and LocationsFury confirmed his Dublin plans through an Instagram story, posting a video of himself training in Thailand with the caption: 'Let's go August 1, Dublin, Ireland.' The fight is expected to be part of a card organized by veteran promoter Frank Warren, although no opponent has been named yet. Warren has already ruled out a match against Andy Ruiz Jr, who famously dethroned Joshua in 2019.Meanwhile, Joshua will face Prenga in Riyadh on July 25 in his first bout since being involved in a car crash in Nigeria in December that tragically killed two of his close friends. This fight marks Joshua's return to the ring after a period of recovery and reflection following the accident.The Road to Rivalry: History Between the HeavyweightsThe path to this potential showdown has been building for years. Fury marked his return from a 16-month retirement with a dominant points victory over Russia's Arslanbek Makhmudov in April. Immediately after that win, Fury called out Joshua, who was present at ringside. Rather than facing off directly at the Tottenham Hotspur Stadium, the two engaged in a verbal exchange where Joshua taunted Fury by declaring: 'I'm the landlord. Remember that. You work for me.'Joshua's promoter Eddie Hearn has since added fuel to the fire by stating: 'Signed, sealed, delivered! AJ v Fury is on.' This public confirmation from Hearn suggests the fight is more than just talk, with both sides actively preparing for the eventual clash.The Impact Analysis: Shaking Up the Heavyweight DivisionThe confirmed fights between Fury and Joshua, followed by their anticipated showdown, represent a significant moment for the heavyweight division. Both fighters have held world titles and have massive fan bases in the UK and internationally. Their potential fight would generate enormous pay-per-view revenue and likely be one of the most-watched boxing events of the year.For the division itself, this matchup could clarify the hierarchy of the heavyweight landscape. While other top contenders like Oleksandr Usyk and Deontay Wilder remain in the mix, a Fury-Joshua winner would position themselves as the dominant force in the division, potentially setting up unification fights down the line.The Prediction: What to Expect from the 'Battle of Britain'Given the history between these two fighters and the buildup to their potential showdown, the 'Battle of Britain' promises to be more than just a boxing match—it's likely to be a cultural phenomenon in the UK. The fight will carry significant narrative weight, with both fighters having compelling stories: Fury's journey from retirement back to the top, and Joshua's comeback after personal tragedy.While the exact date and venue for the main event remain unconfirmed, November appears to be the most likely timeframe. With both fighters scheduled to have warm-up fights first, fans can expect to see them in peak condition when they finally meet in what could be one of the most significant heavyweight fights of the decade.