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Doug Allan, a pioneering wildlife cinematographer, died at the age of 74 while on a trek in Nepal, his management firm said, noting he passed away "immersed in nature and surrounded by friends."Best known for his role as principal camera operator on landmark BBC series including Planet Earth, Frozen Planet and The Blue Planet, Allan amassed a remarkable collection of honors, among them eight Emmy Awards, five BAFTAs, and an OBE awarded in 2024 for services to broadcast media and environmental awareness.Born in Dunfermline, Fife, he earned an honours degree in marine biology from Stirling University in 1973 and soon after joined the British Antarctic Survey as a research diver at Signy Island. It was during this period that his passion for filming blossomed, leading to a pivotal encounter with Sir David Attenborough in 1981, which set him on the path to a distinguished career.Allan’s early forays into polar filming began with a 16 mm camera he purchased for an Antarctic expedition, capturing emperor penguins and selling the footage to the BBC—a move that launched his lifelong partnership with the broadcaster.His dedication to extreme‑environment storytelling earned him the Polar Medal twice, underscoring his expertise in filming some of the planet’s harshest locales.In a 2017 interview, Allan revealed he had spent roughly 620 days tracking and recording polar bears. He recounted a memorable moment when a bear’s wet nose brushed a window, likening it to “a squeegee mop cleaning the glass.” Another close encounter saw a hungry walrus seize his legs underwater, which he repelled by striking the animal with his camera.Allan’s visual legacy, described by his representatives as "breathtaking and intimate moments in the natural world," continues to inspire audiences to appreciate and protect Earth’s wonders.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

Britain is confronting the most severe energy shock since the early 1970s, as exports of oil, gas and fertiliser from the Middle East have abruptly stopped. The government says a response plan exists, but details remain vague. It is unclear whether the UK is better prepared for the fallout from Donald Trump’s war with Iran than it was for the pandemic six years ago. Ministers are sending a "we have your back" message to the public while simultaneously signalling to financial markets that any assistance will be limited and targeted. Contingency planning is especially difficult when dealing with an unpredictable leader like Trump. Britain’s heavy reliance on imported energy and food means that reassurance can only hold for a short time. The economy entered the conflict already on shaky ground: unemployment rose steadily throughout 2025 and growth stalled to a virtual standstill in the final quarter of that year. The sudden loss of Middle‑East energy and fertiliser supplies now adds a colossal supply shock. Last year, Trump’s “liberation day” tariff hikes served as a dry run for a far more serious confrontation. This time, the war is taking place in a region that is both volatile and crucial to the global economy. In the past two weeks, the repercussions have been felt across Asia – the Philippines declared a state of emergency, Sri Lanka introduced a four‑day work week, and South Korea announced budget measures to help households cope with soaring energy bills. The continent is the most dependent on Gulf‑exported energy, making the impact there the sharpest. The International Monetary Fund warned that the shock will drive higher prices and slower growth worldwide. Shortages push fuel and food prices up, eroding disposable income, prompting businesses to cut staff, and increasing the risk of recession. The UK, already projected to be one of the poorest‑performing major economies in 2026, could see its fresh graduate cohort face a brutal job market. Trump’s claim that the war could end within two or three weeks appears desperate. Even a rapid cease‑fire would leave substantial collateral damage, creating a stagflation scenario that could hurt Republican prospects in the upcoming mid‑term elections. British officials hope a swift resolution will limit economic damage, allowing a short‑term inflation spike to subside and the Bank of England to resume interest‑rate cuts. Treasury plans include scrapping the planned autumn fuel‑duty rise and providing targeted help for the poorest households, though the path is unlikely to be that simple. Currently, the Treasury is hesitant to act boldly for fear of unsettling bond markets. History – the 2008 banking collapse and the 2020 pandemic – shows that governments can act decisively without triggering a market backlash, using tools such as aggressive rate cuts, increased borrowing, and quantitative easing. The Bank of England has warned of a "substantial negative supply shock" and is expected to soften markets for future rate cuts, which are inevitable. Finance Minister Rachel Reeves could mitigate labour‑market pain by reversing recent increases in employers’ National Insurance contributions, subsidising public transport, and even lowering speed limits to conserve energy. The war, like the pandemic and Russia’s invasion of Ukraine, underscores the fragility of global supply chains and the need for greater British self‑reliance. Investing heavily in renewable energy is essential, but the UK also imports roughly 40% of its food and has not run a manufacturing trade surplus since 1982. In a world of disrupted supply lines, a robust plan for economic self‑sufficiency is more urgent than ever. Larry Elliott is a Guardian columnist.

The England and Wales Cricket Board (ECB) is facing criticism from parents of learning‑disability cricketers who say the board has permitted non‑disabled players to compete in the Disability Premier League (DPL), jeopardising the league’s role as the top feeder for England’s mixed‑disability side.Parents of former England internationals Jai Charan and Alex Jervis claim their sons were replaced by players who do not meet the ECB’s learning‑disability (LD) criteria. An anonymous parent estimates that 12 of the 64 players drafted in December were not disabled, a figure that, if accurate, would represent a significant breach of the league’s purpose.The DPL is intended to be the pinnacle of the pathway to the England Mixed‑Disability team. Under the ECB’s affiliation with Virtus – the global federation for athletes with intellectual impairments – any cricketer seeking an LD spot must demonstrate an IQ of 75 or below, as assessed by an educational psychologist.Owen Jervis, volunteer manager of Yorkshire’s disability team, alleges that several neurodiverse athletes have been fielded despite failing the LD assessment. He notes that most neurodiverse players would not satisfy the eligibility thresholds, citing professional bowler Em Arlott, diagnosed with ADHD and autism in 2023, as an example of a mainstream player with a neurodiverse profile.While the ECB is not legally bound to apply Virtus rules to a domestic competition, critics argue that the inclusion of non‑disabled players undermines the league’s integrity. “You can’t call it a Disability Premier League if the players aren’t disabled,” said Tracey Jervis.Another parent highlighted that his son, a learning‑disability cricketer, is now confined to county disability cricket rather than mainstream county cricket, where many England‑qualified players develop. He warned that the DPL has become an “old‑boys’ club” where selection is driven by personal connections rather than merit.The shift to a mixed‑disability format – combining learning, physical and deaf impairments in the same squads – has further reduced available spots. Parents claim that players without a qualifying LD are occupying key batting and bowling positions, relegating genuine LD athletes to peripheral roles such as fielding or carrying equipment.Owen Jervis raised these concerns with Richard Hill, the ECB’s events and competition manager for disability cricket, in September 2024. Hill acknowledged “several challenges” linked to high‑functioning conditions and said the ECB was drafting an action plan, though Jervis says the situation has worsened.Jai Charan, who debuted for the England LD team in 2023 and holds the DPL’s best bowling average and strike‑rate, and Alex Jervis, a decade‑long LD representative and three‑time LD Ashes winner, were reduced to non‑playing roles in the 2025 season. Charan’s father, Shanial Charan, expressed his disappointment: “My son has the best stats in the league yet he isn’t selected – it feels like discrimination within disability cricket.”The ECB responded that the DPL offers top‑level competition for 60 mixed‑disability players annually, with a strict quota for physical, learning and deaf impairments, making selection highly competitive. It acknowledged ongoing debates about eligibility and indicated a review slated for 2027 to potentially adjust criteria.

Coordinated strikes by United States and Israeli forces hit Tehran, Isfahan and several other Iranian cities on Tuesday, prompting widespread power outages and extensive damage to civilian sites. The Ministry of Energy confirmed that shrapnel from the raids ruptured a primary power‑transfer line, but the outage was restored within a few hours. Among the most critical targets was the Tofigh Darou pharmaceutical complex in the Karaj industrial zone. The facility, which supplies over 90% of Iran’s domestically produced medicines—including cancer and multiple‑sclerosis treatments—sustained heavy damage from multiple projectiles. In central Iran, Isfahan endured a barrage of heavy bunker‑buster bombs over a nearby mountainous area, likely aimed at military installations. The explosions triggered secondary blasts that illuminated the night sky and produced reverberating shockwaves across the city. North‑west of Tehran, in Zanjan, a building identified as the administrative department of the Hosseinieh Azam religious centre was struck, resulting in at least four fatalities and several injuries. Iranian authorities now claim that more than 2,000 people have been killed by US‑Israeli attacks since the conflict erupted on 28 February, with residential blocks, schools, hospitals and historic sites also affected. Additional targets this week included civilian nuclear facilities, major steel producers, petrochemical plants, and the Iran University of Science and Technology, where an imaging satellite was developed. A professor linked to Iran’s missile programme and his two children were assassinated at their home in northern Tehran. U.S. President Donald Trump reiterated threats to strike Iran’s oil and gas infrastructure, power plants and water‑desalination facilities. Despite the onslaught, the Islamic Revolutionary Guard Corps (IRGC) continues to project defiance. A spokesperson for the Khatam al‑Anbiya Central Headquarters declared that Tehran’s adversaries are “humiliated and on the path of destruction,” while senior commander Ali Fadavi warned that American warships are vulnerable and allegedly transmit false transponder signals. The IRGC also released footage of ballistic missiles aimed at Israel and surrounding nations, and claimed to have downed two U.S. MQ‑9 Reaper drones, promising retaliatory strikes against technology firms linked to the United States and Israel. Domestically, the judiciary announced the execution of two members of the foreign‑based Mojahedin‑e‑Khalq (MEK) group, labeling them terrorists. This follows a series of recent executions tied to the January protests and broader dissent. Authorities also issued new indictments against roughly 200 individuals accused of assisting the U.S. and Israel, including alleged “mercenaries” who disseminated strike footage abroad. Penalties for national‑security offenses now encompass asset confiscation and capital punishment. President Masoud Pezeshkian convened his first cabinet meeting since the war’s onset in a makeshift, blue‑covered space, emphasizing that any peace negotiations will safeguard Iran’s “dignity, security and national interests.” Israel’s Channel 14 reported that Pezeshkian sought greater negotiating leverage with the United States, a request allegedly rebuffed by IRGC chief Ahmad Vahidi.

David Attenborough’s voice returns to British screens in ‘Secret Garden’, a BBC One series launched to celebrate the network’s 100th birthday. Unlike his classic wildlife documentaries, the show turns the lens toward the UK’s own backyards, exploring how gardens can rival tropical rainforests in biodiversity.Series producer Bill Markham explains that the programme deliberately avoids the usual “lions and tigers” spectacle, aiming instead for a relatable, garden‑centred narrative. He notes that British gardens collectively cover more area than all national nature reserves combined, and that an average garden can host up to 2,600 different species.The series tackles the contentious issue of domestic cats. With 9.5 million pet cats in Britain, Attenborough reveals they may kill around 55 million birds each year. Simple measures—such as fitting cats with bells—can slash hunting success by one‑third, while raising bird feeders reduces fatalities further.Markham stresses that the current predator‑prey balance is “unfair on the prey”, noting that cats are “the biggest predator in our gardens” yet are constantly fed, leading to an unsustainable population. He cites ecologist Dr Davide Dominoni, who suggests that keeping cats indoors during the breeding months of April and May could dramatically lower bird deaths.Beyond cats, the series examines other garden‑linked wildlife challenges. Each year, over 30 million pheasants—an Asian species—are released into the countryside, where they prey on native insects, reptiles, and amphibians. Markham argues that despite the countryside lobby’s claim that pheasant shooting sustains rural jobs, the practice “mess‑es with the ecology”.‘Secret Garden’ also showcases rare footage, including a pine marten hunting sand martins, an otter preying on ducks, and intricate mayfly battles reminiscent of the famed “snakes vs. iguana” scene from Planet Earth II. These moments underline the hidden drama unfolding in everyday green spaces.Markham hopes the series will soothe the growing eco‑anxiety many feel about climate change. He points out that the UK boasts roughly 25 million gardens, with 80 % of the population having access. Simple actions—like planting a native tree to boost caterpillar supplies for birds—can make a measurable difference.While the show may provoke cat owners and countryside advocates, Markham believes the nation’s love for “animals, gardens and David Attenborough” will drive a collective re‑thinking of garden stewardship. As Attenborough reflects, his first encounter with nature likely occurred in his own garden, setting him on the path to becoming the world’s most renowned naturalist.‘Secret Garden’ airs from 5 April on BBC One and iPlayer.

Islamabad became the focal point of a new diplomatic track when the foreign ministers of Saudi Arabia, Turkey and Egypt arrived this weekend, joining Pakistan’s Deputy Prime Minister and Foreign Minister Ishaq Dar. The quartet pledged to channel U.S. and Iranian confidence in Pakistan’s ability to host direct talks aimed at a comprehensive settlement. At the close of the meeting, Dar announced the creation of a Committee of Four—senior officials from each foreign ministry tasked with ironing out the procedural details of the peace process. The gathering marks the evolution of a broader Arab‑Islamic consultative effort that began in Riyadh on March 19 into a focused four‑nation push, with Pakistan positioned as the primary conduit between Washington and Tehran. In a candid interview with the Financial Times, U.S. President Donald Trump declared his “favourite thing is to take the oil in Iran,” hinting at a possible seizure of Kharg Island, which handles roughly 90 % of Iran’s crude exports. He reiterated an April 6 deadline for Tehran to accept a deal or face U.S. strikes on its energy infrastructure, yet on Air Force One he added, “I do see a deal in Iran, yeah. Could be soon,” describing the negotiations as “extremely well” progressing. Analysts stress that these mixed signals underscore the central tension confronting Pakistan’s initiative. While Islamabad and its partners are building a multilateral framework to curb escalation, Israeli strikes continue and the U.S. military presence in the region expands. Key diplomatic insights came from former Pakistani officials. Former information minister Mushahid Hussain Sayed highlighted the meeting as the first institutional Muslim‑world effort to open a dialogue pathway, noting that Pakistan and Turkey are among the most credible interlocutors—one a nuclear power, the other a NATO member. He cautioned, however, that the steps are “baby steps” in a war that is rapidly complicating. Former ambassador Masood Khan described the Committee of Four as a structured back‑channel enabling a “step‑by‑step, layered, and calibrated process.” He outlined four potential stages: trust‑building measures, cease‑fire negotiations, direct talks on the nuclear programme and the Strait of Hormuz, and finally reciprocal commitments. Khan warned that Iran’s demands for war reparations and sovereignty over the Strait could prove the toughest hurdles. High‑level outreach extended beyond the region. Pakistan’s Prime Minister Shehbaz Sharif held a 90‑minute call with Iranian President Masoud Pezeshkian, while China’s Foreign Minister Wang Yi pledged full backing for the initiative. A senior Pakistani diplomat confirmed Dar’s planned visit to China on March 31, underscoring the strategic weight of the Pakistan‑China relationship. On the economic front, Iran’s agreement to allow 20 Pakistani‑flagged vessels through the Strait of Hormuz represents the most immediate confidence‑building measure. The strait remains effectively closed to regular shipping, prompting the International Energy Agency to label the disruption as the “worst oil shock in history,” surpassing the crises of 1973 and 1979. Brent crude surged above $116 per barrel, up more than 50 % since the war began on February 28, while WTO Director‑General Ngozi Okonjo‑Iweala warned of the “worst trade disruptions in the past 80 years.” Nevertheless, experts argue that the Strait should not become the centerpiece of any settlement. The long‑term resolution will likely involve all eight littoral states under UNCLOS and established legal precedents, with the immediate priority being a broader halt to hostilities. Military dynamics remain volatile. U.S. Central Command reported that an amphibious task force of roughly 3,500 Marines and sailors aboard the USS Tripoli arrived in the region, with an additional 2,200 Marines and 2,000 soldiers from the 82nd Airborne Division slated to deploy. Trump affirmed that military options are still on the table, and reports suggest the Pentagon is preparing for potential ground operations. Iran’s leadership remains skeptical. A spokesperson for Iran’s Ministry of Foreign Affairs described the U.S. 15‑point plan—calling for a one‑month cease‑fire, handover of highly enriched uranium, a halt to enrichment, missile curbs, and an end to proxy support—as “unrealistic, illogical and excessive.” Tehran’s counter‑proposal, aired on Press TV, demands a halt to aggression, concrete guarantees against recurrence, reparations, and formal recognition of Iranian sovereignty over the Strait of Hormuz. Analysts such as Reza Khanzadeh of George Mason University argue that the burden of compromise falls on Washington, noting that Iran will not sacrifice regime survival. Meanwhile, former diplomat Masood Khan identified the most decisive confidence‑building measure as a U.S. commitment to halt Israeli attacks on Iran and Lebanon—a step he admits is “easier said than done.” In sum, Pakistan’s diplomatic corridor offers a glimmer of hope, but deep mistrust, divergent demands, and an accelerating military buildup render the path to a lasting settlement precarious.

Recent developments indicate that potential military action against Iran is encountering significant political resistance from an unexpected source: supporters of the MAGA movement. This internal opposition within American political circles has created a complex dynamic for policymakers considering engagement with Iran. The emergence of MAGA-aligned voices opposing potential conflict with Iran represents a notable shift in traditional foreign policy alignments. Political analysts suggest this development could influence the administration's approach to Middle East diplomacy and military strategy. As tensions potentially escalate in the region, the intersection of domestic political considerations and international relations continues to shape the trajectory of US-Iran relations. The evolving stance of influential political movements may prove to be a decisive factor in determining the path forward.

The US Secretary of State has made a statement indicating that the ongoing war could conclude in 'weeks, not months', offering a glimmer of hope for a swift resolution to the conflict. The Secretary's comments have garnered significant attention, as they suggest a potential shift in the dynamics of the war.While details about the Secretary's statement are limited, the prospect of a rapid conclusion to the conflict has sparked optimism among some observers. The possibility of a negotiated settlement or a significant escalation in diplomatic efforts has raised hopes that the war could be brought to an end sooner rather than later.However, it remains to be seen whether the Secretary's comments will translate into tangible progress in the conflict. The path to peace often proves complex and fraught with challenges, and it is unclear what specific steps will be taken to achieve a swift resolution.