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The LeadWhen Keir Starmer won a landslide Labour majority promising to pursue five governing "missions", the high-profile leftwing economist Mariana Mazzucato was credited as an inspiration. Two years on, her bracing new book helps shed light on why Labour in power has struggled to project the sense of direction that "mission-led government", as Mazzucato calls it, requires.A New Framework for Economic PolicySynthesising and extending her earlier work, here she proposes "a new economics of collective action around the common good". From this perspective, the economy is not a concatenation of rapacious independent forces, to be contained and offset by public policy, but a project – or rather a series of projects – with direction and purpose.The Five Principles of Common Good EconomicsThe "compass" in the title is really a set of five principles, all of which Mazzucato says such an economy should have: purpose and "directionality"; co-creation by citizens; collective learning; reward sharing; and accountability. Each of these principles is set out in detail. Co-creation implies grassroots participation in designing and redesigning government programmes, for example – because, "when people help define a problem and develop and implement solutions, they see them as theirs rather than something imposed on them".Reward Sharing and PredistributionReward sharing means ensuring the creators or rightful owners of economic value stand to benefit: from Indigenous people whose homes lie near raw material deposits, to social media users whose data fuels Big Tech's profits. That implies radical tax reform – including greater use of wealth taxes – and the robust use of conditions in public contracts, to make sure workers and taxpayers get their fair share: an approach she calls "predistribution".Critique of Labour's Economic ApproachAccording to Mazzucato's definition, Labour's attempt at mission-led government badly missed the mark. Its first and overriding goal – "kickstart economic growth" – cannot be a "mission" at all, because it lacks the necessary purpose. What, in other words, is that economic growth meant to be for? While her scope in this ambitious book is global, the analysis also dismantles Starmer's claim to be pursuing national "missions", by setting out just how radical – and radically different – that would look in practice.Practical Examples and Global Applications"The seeds of transformation are everywhere," she says, citing inspiring projects that range from delivering healthy and sustainable school meals in Sweden to the EU's mission to support cities to become climate-neutral, to the international Nagoya Protocol on sharing the benefits of genetic resources and traditional knowledge. Echoes of Mazzucato's mindset are detectable in some Labour policies – from using the threat of legislation to cajole pension funds to invest more in UK assets, to writing conditions on youth training into clean energy contracts.The Future of Economic DirectionEconomies work best, she believes, when they pursue grand collective goals – developing and distributing a vaccine for a pandemic; or confronting the climate emergency (or, though she doesn't lean on the example here, tooling up for a new and more frightening geopolitical era). We should ask, she says, "not which market failure do we want to be fixed, but what direction do we want the economy to sail in".

Kane Parsons' Historic Achievement Kane Parsons has become the youngest film-maker to open a film at number one at the North American box office for his directing debut Backrooms. The Success of Backrooms Parsons, 20, is seven years younger than the previous record holder, Josh Trank, who was 27 when his debut Chronicle recorded a $22m opening in 2011. Backrooms stunned industry observers by taking $81m in its first weekend in North America – which was also a record for its studio, A24. The Film's Background Backrooms, described by the Guardian’s chief critic Peter Bradshaw as “an icily brilliant and genuinely disturbing conceptual horror film” is based on Parsons’ YouTube series of the same name, inspired by the “creepypasta” of the same name, referring to a fictional space of infinite, interconnected spaces. Addressing Controversy Parsons’ age has led to claims online that he did not in fact direct the film, with actor Mark Duplass responding: ““Hmmm, with all due respect I don’t remember seeing you on set. When I was there, Kane was 100% in control. More so than many directors 3x his age.” Parsons himself also commented on the rumours, saying: “This is actually all true. They don’t tell you this, but 96% of all movies released in North America and Europe are actually directed by the same person. They call him ‘The Older Gentleman’. He has had all of Hollywood in a chokehold for decades now.” Comparison with Other Low-Budget Horror Films Backrooms' box office success follows that of another low-budget horror film, Obsession, directed by Curry Barker. Barker, at 26, is six years older; his film was released on 15 May with a $17.1m opening weekend in North America, and has now recorded $104.7m after four weeks.

The Retaliatory Strike Iran's Islamic Revolutionary Guard Corps (IRGC) says it launched a retaliatory strike on a base used by US forces that it claims was used for an attack on an Iranian communications tower. The IRGC Aerospace Force fighters targeted the airbase where the aggression originated, and the predicted targets were destroyed. The Escalation The attacks come after the United States said it carried out strikes on Iran this weekend in response to 'aggressive Iranian actions that included the shootdown of a US MQ-1 drone that was operating over international waters.' US fighter aircraft swiftly responded by eliminating Iranian air defenses, a ground control station, and two one-way attack drones that posed clear threats to ships transiting regional waters. The Fragile Ceasefire The attacks, the latest in several exchanges of fire in recent days, come as indirect negotiations between the US and Iran to formalize a fragile ceasefire that took effect in April continue. There have been mixed signals about whether the two sides are close to an agreement to extend the fragile truce. The Potential Memorandum of Understanding The two sides have reportedly been reviewing a potential memorandum of understanding (MoU) that would extend the ceasefire for a further 60 days and begin negotiations to end the war permanently. The MoU will state that shipping through the Strait of Hormuz is to be 'unrestricted,' meaning there will be no tolls, no 'harassment,' and that Iran will have 30 days to remove all sea mines. Iran's Response Iran's Foreign Ministry spokesperson Esmaeil ‌Baghaei said on Monday that any delay ⁠in ⁠the diplomatic process to end the war can ⁠be explained by a lack of trust, ⁠Washington's contradictory positions and Israel's attacks on Lebanon. Negotiations have started amid severe suspicion and mistrust, and the exchange of messages is taking place in ⁠this atmosphere. Trump's Statement US President Donald Trump said in a statement on his Truth Social platform late on Sunday, Tehran 'really wants to make a deal' and that whatever deal is reached will 'be a good one' for the US 'and those that are with us.' He lashed out at domestic critics for 'negatively 'chirping'' about his handling of the war but made no mention of the US strikes on Iran.

The Ban on Cenk Uygur and Hasan Piker US political commentators Cenk Uygur and Hasan Piker have been barred from entering the United Kingdom. British authorities cited their public comments about Israel as the reason for the decision. The Event Details Uygur, co-founder of The Young Turks, learned of the restriction while trying to board a flight to London. He was scheduled to attend the SXSW London festival and deliver a speech at Oxford University. Piker, a staunch supporter of Palestine and one of the internet's biggest political streamers, also had his UK visa revoked as he prepared to travel to the same event. The Reason Behind the Ban According to Uygur, British authorities told him he is considered "a serious risk to the public order" due to his criticism of Israel. He claimed that the government stated his comments about Israel's influence on the American government are antisemitic. Piker also stated that the UK used the terminology "not conducive to the public good" when denying him entry. The Impact on Free Speech The restrictions have sparked concerns about free speech and the influence of Israel advocacy organizations on public discourse. Piker stated that "Israel advocacy organisations have unbelievable amounts of power over what even the United Kingdom has to say and do; if you are an avowed anti-Zionist, your travel will be restricted." The Future Implications This incident comes weeks after British authorities barred US rapper Ye from entering the country, citing his history of anti-Semitic remarks. The decision has raised questions about the UK's stance on free speech and its relationship with Israel.

The Lead: US Intervention Amid Escalating Conflict Washington has put forward a proposal to de-escalate hostilities in Lebanon, a United States official has told Al Jazeera, adding that Secretary of State Marco Rubio has held separate talks with Lebanese President Joseph Aoun and Israeli Prime Minister Benjamin Netanyahu. The statement comes as Israel's military has taken over the medieval Beaufort Castle just north of the Litani River in southern Lebanon, conducting its deepest push into the country in decades. The US De-escalation Proposal: Conditions for Ceasefire The US official told Al Jazeera on Sunday that under the proposed "roadmap", Hezbollah would halt all attacks on Israel in exchange for Israel refraining from further escalation in the Lebanese capital, Beirut. The US proposal aims to create a conducive environment for a gradual de-escalation and a complete, comprehensive cessation of all hostilities, the official added. Human Cost of Escalation: Casualties and Displacement More than one million people have been forcibly displaced across Lebanon since the fighting between Hezbollah and Israel escalated on March 2. According to the latest figures from the Lebanese Ministry of Public Health, more than 3,412 people have been killed and 10,269 wounded in Israeli attacks since March 2. Israeli forces killed at least 12 people and wounded 35 in more than 36 attacks across southern Lebanon on Sunday alone, according to an Al Jazeera tally. International Response: Global Condemnation Countries across the world have slammed Israel's escalation of its offensive on Lebanon. French President Emmanuel Macron said "nothing justifies" it. United Kingdom Foreign Secretary Yvette Cooper called on Israel to halt its military activity in Lebanon, saying its escalation had "eroded space for diplomacy". Qatar condemned Israel's continuing attacks on Lebanon and the expansion of its ground offensive in the south, describing the campaign as a serious escalation and violation of international law. Path Forward: Mixed Signals and Continued Tensions Israeli Prime Minister Benjamin Netanyahu, who promised to push deeper into Lebanon and called Sunday's operation a "dramatic shift" in the campaign against Hezbollah, ordered the military on Monday to attack targets in Beirut's southern suburbs, known as Dahiyeh, a stronghold of the Lebanese group. The US official placed responsibility for the current round of fighting squarely on Hezbollah and accused it of following Iran's directives without regard for Lebanese interests. "The quickest way to protect civilians and reduce escalation is for Hezbollah to cease fire immediately," the official said, adding that Washington does not expect Israel to tolerate continued attacks on its civilians.

The Takeover Bid EasyJet has called a potential £3bn bid by a US investment group “highly opportunistic”, as shares in the budget airline shot up to their highest level in three months on the takeover interest. Castlelake's Stake and Offer The US private credit firm Castlelake said on Friday it was considering a takeover offer for the airline. On Monday, it said it had already bought a 2.14% stake in the business and its offer would value easyJet at least at 403p a share, or about £3bn overall. EasyJet's Response However, easyJet hit out at its potential buyer, saying it was “highly opportunistic timing” as its share price was “temporarily depressed due to the current situation in the Middle East and its impact on customer confidence and jet fuel prices”. Market Reaction and Future Outlook Shares in easyJet shot up by as much as 12% in early trading on Monday, reaching 444.7p – well above the minimum level of a potential offer by Castlelake, and their highest level since 2 March, valuing the company at about £3.4bn. The jump later eased, with shares up about 10%. Regulatory Challenges Under City takeover rules, Castlelake, which is headquartered in Minneapolis and manages $36bn (£27bn) in assets, has until 5pm on 26 June to announce whether intends to make an offer for easyJet. EasyJet said it would “consider any proposal, should one be made” but that there were “considerable regulatory, financial and other execution challenges associated with a potential takeover”.

The Latest Escalation in US-Iran Conflict The United States military says it has struck Iranian military sites, and Iran’s Islamic Revolutionary Guard Corps (IRGC) says it has targeted a US base in response, the latest in a series of exchanges as negotiations to end the three-month US-Israel war on Iran are conducted. US Actions and Iranian Response US strikes Iranian sites: The US military’s Central Command (CENTCOM) said it conducted “self-defense strikes” on Iranian radar and drone sites in the city of Goruk and on Qeshm Island at the weekend. Iran targets US base: The IRGC said it struck an airbase that was used for an attack on a telecommunications tower on Sirik Island, located in the southern province of Hormozgan, Iran’s Fars news agency reported. Diplomatic Efforts and Regional Impact Iranian Foreign Minister Abbas Araghchi: Iranian Foreign Minister Abbas Araghchi said Tehran is continuing to exchange messages with the US on a deal to end the war. Trump’s stance: US President Donald Trump described Iran as eager to reach an agreement, posting on his Truth Social platform that “Iran really wants to make a deal, and it will be a good one for the USA and those that are with us.” Kuwait intercepts missiles and drones: The General Staff of the Kuwaiti army said its air defences were “confronting hostile missile and drone attacks”. Israel pushes farther into Lebanon: Prime Minister Benjamin Netanyahu has ordered Israel’s military to push farther into Lebanon after Israeli forces made their deepest incursion into the country in more than 25 years. Hezbollah’s Actions and US Proposal Hezbollah downs Israeli drone: The Lebanese armed group said it shot down an Israeli Hermes 450 drone over the western sector of southern Lebanon using a surface-to-air missile on Sunday evening. Hezbollah strikes Israeli forces: Hezbollah also said its fighters fired a large number of rockets and artillery shells at Israeli forces on the eastern outskirts of the town of Yohmor al-Shaqif in southern Lebanon early on Monday. US proposes new plan: The US has put forward a proposal to de-escalate hostilities in Lebanon, a US official told Al Jazeera, adding that Secretary of State Marco Rubio held separate talks with Lebanese President Joseph Aoun and Netanyahu.

The Global Bauxite Rush and Guinea's ContradictionIn the small village of Bembou Silaty, northwestern Guinea, 38-year-old Mamadou Aliou embodies the central contradiction of Guinea's bauxite boom. Working in the environmental health and safety department for a mining company while simultaneously advocating for his community's rights, Aliou represents the complex relationship between global resource demands and local realities."Before these companies arrived, we cultivated our land, and it sustained us," Aliou told Al Jazeera. "We could cover our daily needs, especially food. But now, when a piece of land is registered and belongs to a mining company, you have nothing there any more."The Strategic Value of Guinea's Bauxite ReservesGuinea holds the world's largest reserves of bauxite, the ore that becomes alumina and ultimately aluminum—a metal essential for car and aircraft frames, windows, wind turbines, and solar panels. Over the past three decades, the country has multiplied its bauxite production tenfold, with more than a dozen ongoing projects currently operating.As the global energy transition demands ever more aluminum, Guinea has found itself in a strategically crucial position. Approximately 75 percent of the bauxite exported by the country over the past decade has ended up in China, which produces 60 percent of the world's aluminum. Companies from Russia, the United States, and the United Arab Emirates have also established significant operations in the country to secure this valuable resource.Economic Disparities and Compensation ChallengesIn the traditional bauxite heartlands of Kindia and Boke, the main roads are notably well-maintained, and steady jobs in technical roles or transport logistics have created economic opportunities for some Guineans. In Bembou Silaty, however, the situation remains starkly different—a quiet village without electricity, where farming methods remain untouched by mechanization.People working in technical roles at the mine can earn up to about $300 a month, a significant sum in Guinea. For other locals who make a living from farming, most don't have a regular wage and rely on the yield from their crops. Across Guinea, an estimated half of the population depends on agriculture for their livelihood.Locals in Bembou Silaty say every hectare claimed by mining is a hectare lost to farming, in a country that spent more than $500m importing rice in 2024. "They give you compensation for your land, but it's not enough, and in the end, it's mismanaged," Aliou said. "Within a month or two, someone who received 50 or 100 million Guinean francs ($5,700-11,400) has nothing left. No land, no money. They have to start over, from below zero."Environmental Degradation and Water ContaminationThe environmental impact of bauxite mining in communities like Bembou Silaty has been profound. Not all homes in the village of about 5,000 have indoor toilets and plumbing. While a new water point serves nearly all residents, the water contains iron contamination.In neighboring villages, the situation is even more dire. "Since the mining companies came, we've had this problem with the water. The children get sick, and the parents too," said Mariama Kindi Diallo, a farmer. "The doctors tell us not to drink the rain or river water. There are no roads, no school, no phone signal. What are we supposed to do? We are asking for help to have a dignified life."Environmental concerns extend beyond water contamination. Surgical holes drilled into the ground mark where mining companies have tested for bauxite—a reminder to farmers that the impact on the land is felt even before extraction begins. In a recent report, Djami Diallo, the Guinean minister of the environment and sustainable development, stated that each year, certain companies had their impact studies and evaluation reports rejected for failing to comply with environmental standards.The Government's Push for Value AdditionTo address these challenges and increase the benefits for Guinea, the government of Mamady Doumbouya, which came to power in a 2021 coup, is attempting to reorganize the mining sector. It is pressing investors to process bauxite within Guinea, ensuring a portion of the value stays in the country.Processing bauxite into aluminum can multiply its price by 37 times. Instability in Iran amid the US and Israel's war has contributed to rising aluminum prices, which surpassed $3,600 per tonne in April. Doumbouya is set to lead the country for the next seven years, after winning the December 2025 elections with nearly 87 percent of the vote.Achieving this transformation, however, requires a huge increase in electricity generation—power that is non-existent in villages like Bembou Silaty and unreliable even in the capital, Conakry. Guinea is working with neighboring Senegal on a solution: Using Senegalese gas to generate enough electricity to process its bauxite on African soil.The Global Trail of Bauxite and MigrationThe story of Guinea's bauxite extends far beyond its borders. More than 3,000km away, in Parets del Valles, Spain, the journey's end plays out. For Spain, Europe's largest consumer of Guinean bauxite, more than 90 percent of its imports come from Guinea.The aluminium produced there feeds the automotive industry and serves both industrial and domestic purposes. In Spain, there is light, hot water, paved roads—all the base elements of a decent life that remain elusive in many parts of Guinea.Increasingly, more boats are leaving directly from Guinea, towards the Canary Islands and on to mainland Europe. According to Frontex, the European Union border security agency, more Guineans arrived in the Canary Islands, Spain, in 2023 (2,324) than in the previous 13 years combined. In 2024 and 2025 combined, another 6,000 Guineans arrived.Many left, following the bauxite trail, hoping to find something more in the places where their resources are both enjoyed and exploited. "If you compare the bauxite we export with what we get in return, the difference is enormous," Aliou reflects. "We gain almost nothing. Just enough to survive."

Scientists from University College London and partners have proved that a 50‑gene genomic test can reliably pinpoint hormone‑positive breast‑cancer patients who do not need chemotherapy, potentially sparing millions from toxic side‑effects.Optima Trial Demonstrates Genomic Test Can Identify Low‑Risk PatientsThe Optima trial enrolled 4,429 women aged 40+ across the UK, Norway, Sweden, Australia, New Zealand and Thailand. Participants were split into a standard‑care arm (chemotherapy + hormone therapy) and a test‑guided arm where treatment was decided by the genomic score.Trial Numbers Reveal Near‑Identical Survival RatesFive‑year outcomes were strikingly similar:95% of patients receiving chemotherapy remained alive and recurrence‑free.94% of patients who skipped chemotherapy (low‑score group) were also alive and recurrence‑free.The test classified patients using a score derived from the activity of 50 tumour genes, produced by Veracyte's Prosigna assay.These figures indicate that for low‑score patients, chemotherapy adds little or no survival benefit.Potential Shift in Breast Cancer Treatment GuidelinesProf Rob Stein, chief investigator, says the results “address a longstanding challenge” by moving decision‑making from clinical features to tumour biology. Health systems could see reduced drug costs, fewer hospital visits, and a dramatic drop in chemotherapy‑related toxicity.Future Adoption and Healthcare SavingsWith funding from the NIHR, Veracyte and cancer charities, the study paves the way for rapid guideline updates at bodies like ASCO and NICE. Wider implementation could translate into billions of dollars saved globally and improve quality of life for countless patients. Ongoing monitoring will confirm long‑term outcomes, but the early data suggest a new era of personalised, cost‑effective breast‑cancer care.