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Recent CDC data reveal a dramatic 1,200% increase in kratom‑related poisonings across the United States over the last ten years, with the most pronounced surge recorded in 2025. Researchers link this rise to the growing presence of 7‑hydroxymitragynine (7‑OH), a synthetically produced compound that mimics kratom’s effects but carries opioid‑like risks. Walter Prozialeck, pharmacology professor at Midwestern University, said the trend was expected, noting that the synthetic alkaloid has entered the market through energy drinks and other products since 2024. Christopher McCurdy of the University of Florida warned that marketing 7‑OH as “enhanced kratom” blurs the line for consumers, turning poison‑control calls into a conflated metric for both natural and synthetic products. By contrast, natural kratom (Mitragyna speciosa)—a Southeast Asian plant used for centuries as a pain reliever—has demonstrated a relatively favorable safety profile in animal and human studies. A 2018 statement from then‑HHS Secretary Brett Giroir rejected the DEA’s push to schedule kratom as a Schedule I substance, citing insufficient evidence of harm. Despite the scientific distinction, several states have moved to implement or propose blanket bans on all kratom products, prompting concern from clinicians and patient advocates. A recent user survey indicated that about 50% of respondents rely on kratom for chronic pain, while roughly 40% use it during addiction recovery. Personal testimonies underscore the plant’s therapeutic role. Jeff Maslan, a 68‑year‑old Californian with severe osteoarthritis, credits kratom with easing opioid withdrawal after multiple surgeries. Similarly, “Steven,” a disabled California resident, describes how kratom eliminated unbearable oxycodone withdrawal symptoms without producing the euphoric “warm fuzzy” feeling typical of opioids. Researchers emphasize that 7‑OH carries genuine opioid hazards, including addiction, severe withdrawal, and respiratory depression that can lead to fatal overdose. In animal models, 7‑OH demonstrated the same respiratory‑depression risk as classic opioids, whereas kratom’s primary alkaloid did not. Prozialeck and colleagues explain that kratom’s pharmacology is more nuanced: it partially activates opioid receptors while also engaging adrenergic and serotonin pathways, resembling a hybrid of a weak opioid and an SNRI‑type antidepressant. This multimodal action likely accounts for its lower euphoric potential and the reported boost in energy among users. Nevertheless, experts caution that kratom is not without risk. Fatal poisonings often involve co‑ingestion of potent opioids such as fentanyl, suggesting that some users may cycle between kratom and stronger substances, raising overdose danger due to reduced opioid tolerance. Additionally, heavy‑metal contamination has been detected in certain kratom batches, though the source—soil, processing, or storage—remains unclear. Given these complexities, the consensus among scholars like Austin Zamarripa (Johns Hopkins) is that natural kratom should remain accessible, while concentrated 7‑OH products merit stricter regulation. “These products may offer meaningful benefits to some individuals, and those benefits could be lost if access is restricted too broadly,” Zamarripa said, urging a differentiated policy approach. As the debate unfolds, patients like Steven worry that a sweeping ban would ignore the nuanced safety profile of the plant. “There’s corn on the cob, there’s high‑fructose corn syrup, there’s whiskey— all derived from corn but fundamentally different,” he remarked, highlighting the need for targeted, evidence‑based regulation rather than a one‑size‑fits‑all prohibition.

Booking.com, a leading accommodation reservation website, has suffered a significant data breach that has exposed customer information to unauthorized parties. The company, which lists over 30 million accommodation venues worldwide, detected suspicious activity involving unauthorized access to some guests' booking information.Upon discovering the breach, Booking.com took immediate action to contain the issue and updated the PIN numbers for affected reservations. The company has also informed affected customers about the breach. According to Booking.com, financial information was not accessed during the breach.The breach is the latest in a series of cybercrime attempts on Booking.com, which has recently struggled with a rising number of online scams on its platform. In 2018, the company reported a breach that exposed the booking data of over 4,000 people. Booking.com was fined €475,000 for reporting the breach 22 days late to the Dutch privacy regulator.The company, owned by Booking Holdings, a $137 billion US company, employs over 24,000 people worldwide. The breach highlights the growing concern of fake listings on booking websites and the need for increased cybersecurity measures in the industry.

Oil prices jumped back above $100 a barrel and global stocks fell after weekend talks between the US and Iran ended without an agreement and Donald Trump imposed a blockade of the Strait of Hormuz. The US president announced the blockade on Sunday, targeting Iranian vessels and ships that have paid a toll to Iran for passage through the strait, in an attempt to choke off the flow of Iranian oil.US Central Command said it would start at 10am ET (5.30pm in Iran and 3pm in the UK), blocking all Iranian Gulf ports and coastal areas, in effect seizing control of maritime traffic in the Strait of Hormuz. The news drove oil and gas prices sharply higher again, after the two-week ceasefire between the US and Iran announced on Wednesday prompted a sharp fall in energy prices, and crude ended the week below the psychological $100 a barrel threshold.Brent crude rose by nearly 7% to $101.74 a barrel on Monday morning, while US crude is up more than 8% to $104.69 a barrel. Gas prices also increased, with the British wholesale gas contract for May soaring by 11.7% to 122.5p a therm. Analysts at JPMorgan Chase said last week they expected oil prices to stay high in the second quarter, above $100 a barrel, before easing in the second half of the year.Most Asian stock markets fell on Monday, with Japan’s Nikkei down 0.7% and Hong Kong’s Hang Seng index losing 1%, while Chinese stocks rose slightly. Sentiment was helped by Beijing’s announcement of a 10-initiative strategy aimed at deepening ties with Taiwan. European stocks also fell, led by airlines including Lufthansa, Wizz Air, easyJet and British Airways parent IAG. The FTSE 100 index in London lost 0.4%, dropping 45 points to 10,555. Germany’s Dax fell 1%, Italy’s FTSE MiB slipped 0.7% and Spain’s Ibex was down 1.1%. With oil and gas prices rising sharply higher, energy companies such as BP and Shell are rallying.Priyanka Sachdeva, senior market analyst at the broker Phillip Nova, said: “In today’s environment, every barrel of risk added to oil markets carries an inflation price tag for the global economy.” She added: “The market reaction underscores a simple but powerful reality: Hormuz risk is not theoretical; it is structural, and it is real.”Interest rate expectations have shifted again; investors now see an 84% chance of two rate increases from the Bank of England this year to tackle rising inflation, up from 60% on Friday. Before the Iran war, the central bank was expected to cut rates. The price of gold fell 0.4% to $4,730.75 an ounce as the blockade fuelled inflation concerns, prompting traders to scale back expectations for Federal Reserve rate cuts this year.

In the quiet town of Iseyin, about 200 km north‑west of Lagos, shaded courtyards and narrow lanes have become the beating heart of Nigeria’s iconic aso‑oke textile industry. Under makeshift sheds, weavers operate wooden looms that have remained largely unchanged for generations. Recent years have seen a surge in demand for the thick, multicoloured fabric, driven by the Nigerian diaspora and an expanding international appetite for African fashion. Yet the craftsmen and women of Iseyin staunchly oppose the introduction of machines, arguing that the hand‑woven process is essential to the cloth’s distinctive texture and cultural value. The craft now serves as an economic lifeline. Young Nigerians—including university graduates—are flocking to Iseyin to learn the trade, attracted by the promise of a steady income. One such convert, Waliu Fransisco, abandoned a career as a Lagos nightclub singer a decade ago to master the loom. At 34, he says, “I now earn a decent living from weaving aso‑oke and I’m satisfied.” Aso‑oke, literally meaning “cloth from the up‑country,” has become a staple in Nigeria’s fashion scene, appearing in ceremonial attire, contemporary streetwear, and even high‑profile outfits such as the wrapper and shawl worn by Meghan Markle during her 2024 visit to Nigeria with Prince Harry. Traditionally, the fabric was produced from locally sourced cotton or silk, with threads hand‑spun, dyed, and woven in limited colour palettes. Today, most weavers use loom‑ready yarns imported primarily from China, allowing for a broader spectrum of hues while preserving the labor‑intensive hand‑weaving technique. Each loom requires meticulous arrangement of narrow, tightly patterned strips that are later sewn together to form the wider cloth used for garments and accessories. “This is what Iseyin is known for,” says 35‑year‑old weaver Kareem Adeola, echoing the sentiment of a community that views the craft as a direct inheritance from its forebears. As global fashion houses and consumers continue to seek authentic African textiles, the artisans of Iseyin stand at the crossroads of tradition and market opportunity, proving that cultural heritage can thrive alongside modern demand.

FIFA has officially declined the Iranian Football Federation’s (FFIRI) appeal to relocate its 2026 World Cup games from the United States to Mexico, stating that the logistical complexities of moving the matches are prohibitive, Mexican President Claudia Sheinbaum confirmed. The request, lodged last month, was met with a firm response from the sport’s governing body: all scheduled fixtures will proceed in the United States as originally drawn, eliminating any prospect of Mexican venues hosting Iran’s team. Sheinbaum reiterated the stance at a press conference in Mexico City, emphasizing that “FIFA ultimately decided that the matches cannot be moved from their original venues,” and that attempting relocation would create untenable logistical hurdles. FIFA declined to comment to Al Jazeera regarding the confirmation of Iran’s host venues. The backdrop to this dispute is the ongoing US‑Israel war against Iran, which erupted on 28 February, killing Supreme Leader Ali Khamenei and 168 people in a girls’ school on the first day of hostilities. Tehran retaliated with missile and drone strikes on Israeli and U.S. military installations across the Middle East. A Pakistan‑mediated ceasefire halted the exchanges on Wednesday, though Israel continues operations in parts of Lebanon. Iran was among the earliest qualifiers from the Asian confederation and is placed in Group G alongside Belgium, Egypt and New Zealand. The team’s three group matches are slated for the U.S. West Coast: Los Angeles on 15 June and 21 June, and Seattle on 26 June. While Mexico, a co‑host of the tournament with the United States and Canada, initially expressed willingness to accommodate Iran’s fixtures, President Sheinbaum’s recent remarks align with FIFA President Gianni Infantino’s position. Infantino, who met Iranian players, coaches and officials in Turkey on 31 March, affirmed that “the matches will be played where they are supposed to be, according to the draw.” Infantino also dismissed speculation that Iran might boycott the tournament altogether after FFIRI President Mehdi Taj warned of a potential boycott if security could not be guaranteed in the United States. Earlier, former U.S. President Donald Trump posted on social media that Iran’s participation would be unsafe, prompting Taj to state that Iran would refuse to travel to America under those conditions. Iranian Sports Minister Ahmad Donyamali later warned that Iran’s World Cup involvement remains uncertain unless FIFA relocates the games, underscoring the political sensitivity surrounding the event. In summary, despite regional conflict, diplomatic tensions, and security concerns voiced by Iranian officials, FIFA’s decision ensures that Iran will compete in the United States as originally scheduled, preserving the tournament’s logistical integrity.

Ukraine and Russia have exchanged accusations of violating the Orthodox Easter ceasefire, as the conflict between the two nations continues to escalate. The truce, which was agreed upon for 32 hours, was intended to provide a temporary reprieve from hostilities during the religious holiday.According to the Ukrainian military's general staff, 2,299 ceasefire violations were recorded, including 28 enemy assault actions, 479 enemy shellings, and 747 strikes by attack drones. In response, Russia's Ministry of Defence accused Kyiv of nearly 2,000 breaches, including 258 artillery or tank attacks and 1,329 FPV drone strikes.The ceasefire violations have raised concerns about the prospects of a lasting peace agreement. The Kremlin has stated that it will not extend the truce unless Kyiv accepts its terms, which include control of 17-18 percent of Ukraine's disputed Donetsk region. Ukraine has proposed freezing the conflict along the current front lines, but Russia has rejected this, seeking control of the entire Donetsk region.Despite the challenges, the truce did bring some relative calm to the region, with the Ukrainian army reporting no long-range Shahed drone attacks, guided aerial bombings, or missile strikes during the ceasefire period. However, the conflict has continued to take a toll on civilians, with Governor Alexander Khinshtein of Russia's Kursk region accusing Kyiv of breaking the ceasefire by attacking a petrol station, injuring three people, including a baby.

The recent ceasefire talks between the United States and Iran have ended without a breakthrough, with Iran's chief negotiator, Mohammad Bagher Ghalibaf, blaming the US for the failure of the talks held in Islamabad, Pakistan. The talks, which were the first direct engagement between the two countries at this level since the 1979 Iranian Revolution, exposed deep divisions on core issues.The US framed the lack of a breakthrough primarily around Iran's alleged refusal to meet its core demand: a firm commitment not to develop nuclear weapons. US Vice President JD Vance said Washington had made its 'red lines' clear and presented what he described as a 'final and best offer'. However, Iran downplayed expectations and blamed the US for making unreasonable demands.The main sticking points between Tehran and Washington are:Iran's nuclear programme: The US wants a clear and enforceable commitment that Iran will not develop nuclear weapons – or even the capability to do so quickly. Iran has consistently rejected accusations that it seeks to build nuclear weapons but said it is willing to negotiate limits on its nuclear activities if sanctions are removed.Strait of Hormuz: Who gets to control this strategic waterway, through which almost all of the oil and natural gas exports from the Gulf nations pass, has become a major flashpoint. Iran has floated the idea of charging transit fees to allow ships to pass through the strait, while the US is adamant the strait is reopened free of any tolls.The near shutdown of shipping through the strait has sent global energy prices soaring with many countries, especially in Asia, forced to implement unprecedented austerity measures to soften the impact of fuel shortages. Experts said the near-closure of the strait has caused the worst economic shock since the 1973 oil embargo.

London's Metropolitan Police arrested 523 people aged 18 to 87 during a pro-Palestinian protest in Trafalgar Square, where demonstrators showed support for Palestine Action. The arrests were made for holding placards in support of the group, which was designated a 'terrorist' organisation in July, although a High Court ruling later overturned this ban due to free speech concerns. The protest, organised by Defend Our Juries, drew hundreds of participants who oppose what they describe as the UK government's complicity in Israel's actions in Gaza and the crackdown on peaceful protests. The group criticised police for making arrests despite the government's ban being ruled unlawful. Amnesty International UK condemned the arrests as 'yet another blow to civil liberties', highlighting that police resorted to mass arrests of people holding placards, including an elderly woman with walking sticks. The ban on Palestine Action, which aims to end global participation in Israel's regime, has generated significant backlash, with nearly 3,000 arrests occurring since its imposition. Protesters, including Freya, 28, and Denis MacDermot, 73, expressed their determination to continue opposing what they described as genocide. The Metropolitan Police confirmed the arrests as part of their effort to enforce the law, despite the legal complexities surrounding the ban on Palestine Action.

Iran’s attempt to impose tolls on vessels passing through the Strait of Hormuz has been labeled illegal by Arsenio Domínguez, the head of the United Nations’ International Maritime Organization (IMO). In an interview with Al Jazeera, Domínguez stressed that such charges would set a dangerous precedent for global shipping. Tehran has asserted its right to levy fees even after the conflict ends, while U.S. President Donald Trump floated the idea of a joint U.S.-Iran venture to collect the payments. Both proposals clash with established maritime conventions. "Countries do not have the right to introduce tools or payments or charges on these straits," Domínguez said, adding that any toll system would be contrary to international law and could cripple the free flow of trade. The remarks came as marathon cease‑fire negotiations between U.S. and Iranian officials in Pakistan concluded without an agreement. U.S. Vice President JD Vance noted that Tehran rejected Washington’s terms, which included a commitment to forgo nuclear weapons development, prompting the American delegation to depart Islamabad after presenting its "final and best offer." Iran’s state‑run Press TV blamed the stalemate on what it called the United States' "excessive demands," citing the toll issue and the nuclear programme as major points of contention. Despite a two‑week cease‑fire announced earlier in the week, maritime traffic remains severely limited. Only 22 vessels with active AIS signals exited the strait between the truce’s start and Friday, a stark drop from the pre‑conflict average of about 135 daily transits, according to S&P Global. The bottleneck is throttling oil and natural‑gas exports from the Gulf. The U.S. military reported that two warships had navigated the waterway to clear Iranian mines, a move Iran denied. President Trump later insisted the strait would reopen "fairly soon," with or without Tehran’s cooperation. Domínguez emphasized that ending the hostilities is the fundamental solution to restoring safe passage. He warned that any resumption of traffic must be accompanied by thorough de‑mining and safety checks to protect both vessels and crews. He also dismissed calls for new legal frameworks, noting that the 1968 traffic‑separation agreement between Iran and Oman—which splits the strait into north‑ and south‑bound lanes—had functioned effectively before the war and does not require revision. Humanitarian concerns feature prominently in Domínguez’s statements. He highlighted that roughly 20,000 seafarers are stranded in the Gulf due to the blockade, warning that prolonged isolation would not only harm these workers but also have a negative ripple effect on the global economy.