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GSK has revealed promising early results for its treatment for gynaecological cancers, Mocertatug Rezetecan (Mo-Rez), as its chief executive, Luke Miels, seeks to speed up drug development at the group.The company reported that in an early-stage trial, Mo-Rez shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer.GSK acquired the Mo-Rez cancer treatment, an antibody-drug conjugate (ADC), from China’s Hansoh Pharma in late 2023, and has trialled it in 224 patients around the world, including the UK, over the past year. Few patients needed to stop treatment because of side-effects, the most common being nausea. It is administered every three weeks via intravenous infusion.Combined with data from a separate, intermediate trial in China, these results give GSK the confidence to go straight to late-stage trials, with five clinical studies planned globally in the next few months, including on patients in the UK.Presenting the results at the Society of Gynecologic Oncology’s annual meeting on women’s cancer in Puerto Rico, Hesham Abdullah, GSK’s global head of cancer research and development, said: “Treatment of gynaecological cancers remains a major challenge, with a pressing need for new therapies that offer improved response rates. With Mo-Rez we now have compelling evidence of a promising clinical profile.”Endometrial cancer affects 1.6 million women globally, with 417,000 new cases each year. Ovarian cancer affects 843,000 people, with 240,000 new cases annually.Abdullah described Mo-Rez as a “key asset” in the company’s growing cancer portfolio, expected to be a blockbuster drug with peak annual sales of more than £2bn, which GSK hopes will help it achieve its 2031 sales target of £40bn.

The evening’s television line‑up offers a mix of heartfelt competition, natural‑history wonder and high‑profile live events, giving viewers plenty of reasons to stay tuned.9 pm – Channel 4 – Your Song: Produced by the team behind The Piano, this new talent show invites ordinary Britons to perform the songs that hold personal meaning. Hosted and judged by Alison Hammond, Paloma Faith and Sam Ryder, the series launches from Liverpool with stories ranging from a teenager’s Bocelli tribute to a lift‑engineer’s pipe‑organ showcase, all racing toward a finale at the Hackney Empire.6 pm – BBC One – Secret Garden: David Attenborough returns to domestic natural history, turning his lens on a modest garden in Bristol. The programme explores the hidden dramas of urban foxes, blue tits and goldfinches, revealing how a tiny plot can host an entire ecosystem.7 pm – BBC Two – Olivier Awards 2026: The Royal Albert Hall hosts the 50th anniversary of Britain’s premier theatre awards, with Nick Mohammed as host. Into the Woods and Paddington: the Musical lead the nominations with eleven each, while Elaine Page receives a Special Award. Rumours swirl about a surprise performance from the awards’ most famous marmalade lover.7.40 pm – Channel 4 – The Great Celebrity Bake Off for Stand Up to Cancer: A comforting Sunday tradition returns, featuring celebrity bakers Ralf Little, Mutya Buena and Mark Wright. Their creations—savory pull‑apart rolls and vegan fruit tarts—aim to raise funds for cancer research.8 pm – BBC One – The Other Bennet Sister: This Pride & Prejudice spin‑off follows Ella Bruccoleri’s Mary as she navigates the attentions of Mr Hayward and Mr Ryder, with a storm‑laden hike adding further tension to the series’ impending conclusion.10.15 pm – ITV1 – Savage River: Australian crime drama starring Katherine Langford returns, following ex‑con Miki Anderson as she attempts a fresh start in her hometown, only to become the prime suspect when a new crime erupts.Film choice – Sky Cinema Premiere – Blue Moon (6.10 am & 7.10 pm): Richard Linklater’s melancholy drama, anchored by Ethan Hawke’s transformative performance, imagines a night in the life of struggling Broadway lyricist Lorenz Hart, whose post‑opening despair leads him to a cocktail of regret.4.15 pm – Channel 4 – Soul: Pixar’s latest metaphysical adventure, co‑directed by Pete Docter and Kemp Powers, follows deceased music teacher Joe (voiced by Jamie Foxx) as he navigates a limbo for unborn souls, meeting the reluctant 22 (Tina Fey) in a story that blends child‑friendly wonder with adult reflections on purpose.Live sport: Premier League action kicks off with Sunderland vs Tottenham at 1 pm on Sky Sports Main Event, followed by Chelsea vs Manchester City at 4.25 pm, offering football fans a double‑header of top‑flight drama.