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The Plant That Changed MedicineGoat's rue or French lilac, Galega officinalis, is a wild plant often grown in gardens for its clusters of attractive lilac or white flowers. For centuries, the plant was used to treat diabetes. Its key ingredient was later identified as galegine, which lowers blood glucose levels but has toxic side-effects.From Natural Remedy to Synthetic SolutionEventually, galegine led to the development of the synthetic drug metformin, now the classic treatment for diabetes by controlling blood sugar. Metformin has none of the toxic side effects of galegine and is now one of the most prescribed drugs in the world. For many years, however, metformin was vilified and banned in many countries because of its association with galegine.The Emergence of a Medical MultitaskerMetformin is now becoming something of a super drug for its anti-cancer effects, cardiovascular protection, delaying the onset of diabetes, and helping some people lose weight. It may even lower the risks for cognitive decline, dementia, strokes, slow aging and increase life expectancy.Understanding the MechanismExactly how metformin achieves all these remarkable wonders is not entirely understood, but it is not bad for a drug that originally came from an attractive wild plant. The scientific community continues to research the multiple pathways through which this simple compound derived from a garden plant can have such profound effects on human health.

The Revelation of a Second Cancer Diagnosis Kylie Minogue has revealed that in early 2021 she was diagnosed with cancer for a second time, after diagnosis and successful treatment for breast cancer in 2005. Details of the Diagnosis and Treatment The pop star discussed the previously unannounced diagnosis in a new Netflix documentary entitled Kylie, available from today. “My second cancer diagnosis was in early 2021. I was able to keep that to myself … Not like the first time,” she said, referring to her highly publicised first treatment. 2005: Diagnosed with breast cancer, treated and given the all-clear. 2021: Diagnosed with cancer for a second time, kept private. The Impact on Her Life and Music Minogue said that after her treatment, she struggled “to find the right time” to announce it publicly, including after the huge success of her Grammy-winning 2023 single Padam Padam. “I don’t feel obliged to tell the world, and actually I just couldn’t at the time because I was just a shell of a person,” she said. “I didn’t want to leave the house again at one point. Padam Padam opened so many doors for me but on the inside I knew that cancer wasn’t just a blip in my life. And I really just wanted to say what happened so I can let go of it. I’d sit through interviews and every opportunity I thought, ‘now’s the time’, but I kept it to myself.” The Netflix Documentary The new Netflix documentary is in three parts, and directed by Michael Harte, who edited Netflix’s successful four-part documentary on David Beckham. As well as Minogue, it features interviews with her sister Dannii, and former duet partners Jason Donovan and Nick Cave, among others. The Importance of Check-Ups Minogue added in the promotional materials accompanying the launch: “There are so many people for whom cancer is part of their life and, I get it; you just want to move on and put it in the past or park it to the side. But, check-ups are incredibly important. It can be daunting and triggering but please be mindful of just how vital they are - and reach out for help if you need it, you’re not alone.”

US health authorities announced that a medical missionary who contracted Ebola in the Democratic Republic of the Congo (DRC) will be flown to Germany for treatment at Charité University Hospital in Berlin.Missionary Contracted Ebola En Route to GermanyThe U.S. Centers for Disease Control and Prevention (CDC) said the patient, identified as Peter Stafford of the Serge Christian mission, will be admitted to Charité following a formal request for assistance from the United States. A CDC spokesperson confirmed that arrangements are being finalised for his admission and treatment.Outbreak Numbers Highlight Growing CrisisThe World Health Organization (WHO) reports that the current Ebola outbreak in the DRC and neighboring Uganda has claimed more than 130 lives and generated over 500 suspected cases. Key figures include:Deaths: >130Suspected cases: >500Geographic spread: DRC and UgandaInternational Health Response and Quarantine PlansWHO Director‑General Tedros Adhanom Ghebreyesus expressed deep concern about the speed of the epidemic. The CDC’s incident manager for Ebola, Dr. Satish Pillai, indicated that six additional high‑risk contacts are slated for transport to Europe, with five headed to Germany and one to the Czech Republic, where they will undergo quarantine monitoring.U.S. officials stressed that the immediate risk to the United States remains low, citing coordinated efforts with state, local, tribal and territorial health departments. Meanwhile, DRC virus expert Jean‑Jacques Muyembe noted that experimental Ebola vaccines are expected from the United States and the United Kingdom.What the Next Weeks May Hold for the OutbreakThe WHO team leader in the DRC anticipates the outbreak will continue for at least another two months. Ongoing international collaboration—including patient transfers, quarantine of contacts, and vaccine shipments—will be critical to contain further spread and reduce mortality.

Clashes on the Gaza Aid Flotilla Israeli forces have fired 'rubber bullets' at activists on a Gaza aid flotilla, according to reports from Al Jazeera. The incident occurred on May 19, 2026, as the flotilla attempted to deliver aid to Gaza. Details of the Confrontation The Israeli military used 'rubber bullets' in the confrontation, which is a type of less-lethal ammunition designed to minimize harm. However, the use of such force still raises concerns about the treatment of activists and the situation in Gaza. Context and Implications The Gaza aid flotilla is an effort to provide humanitarian assistance to the people of Gaza, who have faced significant challenges in recent years. The incident highlights the ongoing tensions in the region and the complexities of providing aid in a conflict zone. International Reaction and Future Developments The international community is likely to closely monitor the situation and respond to the incident. The use of force against activists on a humanitarian mission may lead to increased scrutiny of Israel's actions and calls for greater accountability.

DRC is fast‑tracking the establishment of new Ebola treatment centres after the outbreak’s death toll surged past 200 in early May 2026, prompting urgent action from national health officials and the World Health Organization.Escalating Ebola Outbreak Triggers New Treatment Centre PlansFollowing a sharp increase in confirmed cases across the provinces of North Kivu and Ituri, the Ministry of Health announced a rapid‑deployment programme to build five additional treatment facilities. The plan includes modular units that can be operational within two weeks, aiming to alleviate overcrowding in existing centres.Target locations: Goma, Beni, Butembo, Bunia, and a mobile unit for remote villages.Capacity per centre: 100 beds, with isolation wards and intensive care units.Funding: Joint contribution of $45 million from the DRC government, WHO, and international donors.Rising Cases and Fatalities: The Numbers Behind the SurgeSince the outbreak was declared in March 2026, confirmed infections have climbed to 1,340, with deaths rising to 215. The case‑fatality rate now sits at roughly 16%, up from 12% three weeks earlier.Weekly new cases (last 4 weeks): 180, 210, 250, 300.Vaccination coverage: only 38% of at‑risk populations have received the rVSV‑ZEBOV vaccine.Healthcare worker infections: 42 confirmed, highlighting protective‑equipment shortages.Regional Health Systems Under Strain: Broader ImplicationsThe surge exposes chronic weaknesses in the DRC’s health infrastructure, including limited laboratory capacity and delayed contact‑tracing. Neighboring countries such as Uganda and Rwanda are heightening border surveillance, fearing cross‑border transmission.Laboratory turnaround time: average 48 hours, double the WHO target.Supply chain bottlenecks: delays in personal protective equipment shipments from Europe.Economic impact: local markets in affected provinces report a 12% decline in activity.What Comes Next: Anticipated Responses and ChallengesExperts predict that scaling up treatment capacity alone will not curb the outbreak without parallel advances in vaccination, community engagement, and rapid diagnostics. The WHO plans a supplemental $20 million emergency fund to support mobile labs and expand the vaccine rollout.Short‑term goal: achieve 70% vaccination coverage in high‑risk zones by September 2026.Mid‑term objective: establish permanent Ebola treatment hubs in each affected province.Key challenge: overcoming vaccine hesitancy rooted in misinformation.

The Damascus AttackA car bomb explosion near a Syrian Defence Ministry building in Damascus has killed at least one soldier and wounded more than 20 people, authorities confirmed. According to a statement carried by state media on Tuesday, members of an army unit had discovered an improvised explosive device planted near the site in the Bab Sharqi district of the capital. As they moved to defuse it, a car bomb exploded in the same area, though no additional details were provided.Casualties and ResponseIn addition to the killed soldier, at least 21 people were wounded and transferred to nearby hospitals for medical treatment, said Najib al-Naasan, head of Syria's ambulance and emergency directorate. Videos on social media showed plumes of smoke rising from the scene, with firefighters rushing to extinguish the blaze. There was no immediate claim of responsibility for the attack.Security Context in Post-Assad SyriaSecurity incidents, including explosions targeting military and civilian vehicles, have occurred intermittently in Syria since the fall of longtime President Bashar al-Assad in late 2024 after more than 13 years of war. Reporting from near the site of the attack, Al Jazeera's Heidi Pett noted that the security situation in Syria remains "quite complex." This attack follows a series of similar incidents, including a car bombing that killed at least 20 people on the outskirts of Manbij in northern Syria last year and a suicide bomber attack inside a packed church in Damascus that killed at least 25 people.

The Lead: A Disappointing Return to FormPalme d'Or winning Romanian director Cristian Mungiu presents "Fjord" at Cannes, a drama exploring child abuse allegations within a conservative Romanian-Norwegian family. The review criticizes the film as anticlimactic and underpowered, suggesting it represents a creative misstep for the acclaimed filmmaker.The Film: Cultural Collision and Moral Ambiguity"Fjord" follows Mihai (Sebastian Stan), a Romanian software engineer married to Norwegian woman Lisbet (Renate Reinsve), who relocate to her remote hometown. As fundamentalist Christians, they struggle when their parenting methods come under scrutiny from authorities after their children display bruises. The film explores themes of cultural differences, religious conservatism, and the complexities of the child protection system.Directorial Approach: Mungiu's Signature Style Under ScrutinyThe review notes that while "Fjord" bears Mungiu's signature visual style—enigmatic long shots, avoidance of closeups, and distinctive crowd scenes—it lacks the rewarding complexity and revelation that characterized his earlier work. The film fails to deliver a compelling truth about its relationships while also failing to intriguingly withhold any such truth from the audience.The Performance: Stan and Reinsve in Cultural TensionSebastian Stan portrays Mihai as an ice-cold patriarch whose conservative parenting methods clash with Norwegian social norms, while Renate Reinsve brings depth to Lisbet as she navigates the cultural and legal challenges. The supporting cast, particularly the teenage daughters played by Vanessa Ceban and Henrikke Lund-Olsen, add further layers to the family drama.Festival Context: Auteur Ambitions and International CoproductionsThe review suggests "Fjord" may represent part of an emerging trend at this year's Cannes, where established directors like Mungiu, Kantemir Balagov, and Ryusuke Hamaguchi are creating international coproductions outside their home turf with foreign stars. This phenomenon, potentially resulting from creative conversations at international festivals, may be leading to a loss of focus in their work.Critical Assessment: Moral Complexity Without ResolutionThe film attempts to balance sympathy for the children with understanding for the parents' cultural perspective, while also critiquing a system that may be biased against religious conservatives. However, the review finds the treatment of these themes unsatisfying, with the court case left unresolved and a strangely inert finale that fails to deliver meaningful closure or revelation about the relationship between the teenage girls.Legacy: A Setback for an Acclaimed FilmmakerFor Mungiu, whose 2007 Palme d'Or winning film "4 Months, 3 Weeks and 2 Days" established him as a major voice in international cinema, "Fjord" represents a creative disappointment. While his technical approach remains interesting, the film fails to deliver the depth and complexity that audiences have come to expect from the Romanian auteur.

The LeadIranian human rights activist and 2023 Nobel Peace Prize laureate Narges Mohammadi has returned to her home after being discharged from Pars Hospital in Tehran. The 54-year-old activist, who has been imprisoned since December, requires ongoing medical care following a severe cardiac crisis that led to her hospitalization in early May.The Medical SituationMohammadi was transferred from prison to Pars Hospital in early May after experiencing two episodes of loss of consciousness and a severe cardiac crisis. According to her foundation, she is "scheduled to follow up on her medical complications with her medical team through hospital visits and daily outpatient physiotherapy over the coming weeks". Doctors have emphasized that it is "vital she remains under close medical observation" due to her deteriorating health condition.The Legal BackgroundMohammadi was imprisoned in December after being arrested during a visit to the eastern Iranian city of Mashhad. In February, she was sentenced to more than seven years in prison, with six years of that sentence for "collusion to commit crimes". Her family alleges that her health declined sharply due to a beating she endured during her arrest, which they claim involved multiple men kicking her all over her body. In late March, as she began her prison sentence, she suffered a heart attack.The International ResponseMohammadi's daughter and co-president of the Narges Foundation, Kiana Rahmani, stated that returning her mother to prison would be "a death sentence". She emphasized, "We must ensure she remains free, all baseless charges against her are permanently dropped, and the persecution ends. Human rights activism is not a crime, and no advocate should ever be imprisoned for it." The international community has closely monitored Mohammadi's case, particularly since her Nobel Peace Prize win in 2023.The Future OutlookAs Mohammadi continues her recovery at home, her legal situation remains uncertain. The activist, who has been arrested 13 times and convicted on five separate occasions with sentences exceeding 30 years, faces the ongoing challenge of balancing her medical needs with her legal obligations. Her case has become a focal point for human rights advocates worldwide, particularly regarding the treatment of political prisoners in Iran and the specific challenges faced by women's rights activists in the country.

The Growing Threat of Infectious Diseases The world is becoming less resilient to outbreaks of infectious diseases, experts have warned, as health authorities in the Democratic Republic of the Congo and Uganda scramble to contain an outbreak of Ebola. The Global Preparedness Monitoring Board (GPMB) said in a report published on Monday that "as infectious disease outbreaks become more frequent they are also becoming more damaging", warning that pandemic risk is outpacing investments in preparedness and "the world is not yet meaningfully safer". Climate Crisis and Conflict Driving Disease Spread Disease outbreaks are becoming more likely due to the climate crisis and armed conflict, while collective action is being undermined by geopolitical fragmentation and commercial self-interest, the report said. The GPMB is a group of experts established in 2018 by the World Bank and the World Health Organization (WHO) after the first large scale Ebola outbreak in west Africa and just before Covid-19. Its latest findings come amid global attention on the hantavirus outbreak on a cruise ship and a day after the declaration of an international public health emergency after at least 87 Ebola deaths in the DRC. Current Global Health Crises The two outbreaks "are just the latest crises in our troubled world", WHO chief Tedros Adhanom Ghebreyesus told the opening of the UN agency's World Health Assembly in Geneva. WHO's representative in the DRC, Anne Ancia, told Reuters that in responding to the Ebola outbreak it had emptied its stocks of protective equipment in the capital, Kinshasa, and was preparing a cargo plane to bring additional supplies from a depot in Kenya. The International Rescue Committee and Médecins Sans Frontières aid groups said they had teams responding to the outbreak. Global Preparedness Shortcomings In Geneva, Prof Matthew Kavanagh, director of the Georgetown University Center for Global Health Policy & Politics, said aid cuts may have played a role in leaving the world "playing catch-up against a very dangerous pathogen". He said: "Because early tests looked for the wrong strain of Ebola, we got false negatives and lost weeks of response time. By the time the alarm was raised, the virus had already moved along major transport routes and crossed borders." Advances in Medical Technology vs. Equity Challenges The GPMB report finds that new technologies, including novel vaccine platforms such as mRNA, have "advanced at unprecedented speed" and billions of dollars have been invested in pandemic preparedness and response. But the world is "moving backwards" on measures such as ensuring equitable access to vaccines, tests and treatments, it found. During recent mpox outbreaks, vaccines took almost two years to reach affected countries in Africa, which is even slower than the 17 months it took for Covid-19 vaccines to be distributed. Trust and Global Cooperation Eroding Outbreaks have damaged trust in government, civil liberties and democratic norms, amplified by politicised responses and attacks on scientific institutions, the GPMB warned. These had outlasted the crises themselves and left societies "less resilient to the next emergency", it said. Kolinda Grabar-Kitarović, GPMB co-chair and former president of Croatia, said: "The world does not lack solutions. But without trust and equity, those solutions will not reach the people who need them most." Call for Action and Future Preparedness Countries failed to meet a deadline to finalise the pandemic agreement treaty before this week's World Health Assembly in Geneva, after disagreements over guarantees of access to medical tests, vaccines and treatments in exchange for sharing information on any pathogens emerging on their territories. The GPMB called on political leaders to establish a permanent, independent monitoring mechanism to track pandemic risk, conclude the pandemic agreement to ensure equitable access to vaccines, diagnostic tests and medicines, and put in place financing to secure preparedness and immediate responses to outbreaks. Joy Phumaphi, the GPMB co-chair and a former health minister in Botswana, said: "If trust and cooperation continue to fracture, every country will be more exposed when the next pandemic strikes."