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The LeadRobert Smith, a distinguished pharmacologist and professor at St Mary's medical school in London (now part of Imperial College), has died aged 92. His groundbreaking work on how genetic variations affect drug responses helped shape the field of personalized medicine.The Discovery of Debrisoquine PolymorphismBob became well known for his role in the discovery of "debrisoquine polymorphism." In 1975, as one of five volunteer researchers who took debrisoquine, a blood pressure medication, he was the only one to suffer adverse effects (hypotension) and collapse. This led to the discovery of a genetic polymorphism where certain individuals cannot break down specific drugs efficiently. While Bob described this as an "accident waiting to happen," it positioned him at the forefront of pharmacogenetics.Awards and RecognitionSmith's contributions to pharmacology were formally recognized when he became the first recipient of the Paton prize in 1998 for his work in understanding how genes affect drug response. His academic achievements included becoming professor of pharmacology in 1978 and serving as deputy dean of the medical school from 1980-88.Impact on Medicine and SportsSmith's research fundamentally changed how medical professionals understand drug responses, paving the way for personalized medicine approaches. Beyond human medicine, he applied these principles to horse racing, chairing the UK Horserace Scientific Advisory Committee (1979-99) and its pan-European equivalent (1992-2005). He also served as a director of the Horseracing Forensic Laboratory in Newmarket during the 1990s, helping shape anti-doping protocols.Enduring LegacySmith never fully retired, continuing his research as emeritus professor until publishing his last paper in 2020. His legacy extends beyond scientific contributions to include the principles, warmth, kindness and generosity he embodied throughout his career. His work continues to influence pharmacology and personalized medicine, ensuring his impact will be felt for generations to come.

The LeadA new poll by the AFL-CIO reveals that US workers overwhelmingly support pro-union policies on artificial intelligence, viewing labor unions as the most reliable protectors against AI's potential workplace impacts. The survey shows strong support for human oversight, transparency, and accountability in AI implementation.Union-Backed AI Policies Garner Strong Worker SupportThe poll, conducted with David Binder Research from April 14-22, surveyed 1,588 workers across the United States and found remarkable consensus on AI workplace policies. More than nine out of ten workers surveyed expressed support for policies that labor unions may advocate for, including:95% support requiring a human to be the final decision maker on issues affecting individual workers and their employment92% support advanced guardrails against harmful uses of AI in workplaces94% believe workers should be informed if AI is monitoring their work75% support expanding opportunities for workers to form unions to protect their jobs from AITrust in Unions vs. Other InstitutionsWhen asked which institutions they trust most to protect workers from AI, 38% of workers selected labor unions, significantly more than any other option. Only 17% chose Democrats, 10% Republicans, 6% employers, and 18% selected none of the options. This data indicates a clear preference for worker representation through collective bargaining rather than traditional political channels or corporate oversight.Current AI Implementation and Worker ConcernsThe poll revealed a significant gap between AI implementation in workplaces and transparency to workers. Only 7% of workers reported that their employers disclosed how and when their work is monitored by AI, while 70% said their employers have not disclosed this information. Despite this lack of transparency, 78% of workers rated it as extremely or very important that action be taken to protect them from potential AI harms.Real-World Examples of AI Protection EffortsThe poll results align with recent labor actions where workers have successfully negotiated AI protections in collective bargaining agreements. Anna Iovine, former unit chair of the Ziff Davis Creators Guild, noted how their union won AI protections in their 2024 contract, including editorial integrity safeguards, transparency requirements, and protections against layoffs due to AI implementation. Similarly, Hannah Drummond, a registered nurse with National Nurses United, fought to include AI provisions in her contract to ensure technology affecting patient care would require union approval and wouldn't undermine professional judgment.Future of Labor Relations in the AI Era"These results make it clear: our Workers First Initiative on AI is not just a set of principles, but a mandate to deliver," said Liz Shuler, president of the AFL-CIO. The strong worker support for union-backed AI policies suggests that labor movements will play a central role in shaping how AI is implemented in workplaces. As AI continues to transform industries, collective bargaining agreements may become the primary mechanism for ensuring technology serves workers rather than displacing them. The poll indicates a clear mandate for labor unions to take the lead in establishing workplace AI governance frameworks that prioritize human oversight, transparency, and worker protections.

The Lead: Google's Android Show Unveils AI-Powered FutureGoogle's virtual "Android Show: I/O Edition" event revealed a comprehensive update to its Android ecosystem, featuring new hardware, AI enhancements, and user experience improvements. The announcements underscore Google's strategic focus on integrating its Gemini Intelligence across devices while expanding its hardware partnerships.Googlebooks: Redefining Laptops with AI at the CoreGoogle introduced Googlebooks, a new line of laptops designed from the ground up for Gemini Intelligence. The company is collaborating with major manufacturers including Acer, Asus, Dell, HP, and Lenovo to create these devices launching this fall. Googlebooks will feature "Magic Pointer" - a cursor with built-in Gemini capabilities, seamless integration with Android phones, and custom widget functionality.Vibe-Coded Widgets: Personalization Through Natural LanguageGoogle unveiled "Create My Widget," a feature allowing users to generate custom widgets using natural language descriptions. This innovation will first roll out on Samsung Galaxy and Google Pixel phones this summer. Users can simply describe what they want - such as "suggest three high-protein meal prep recipes every week" - to create personalized dashboard widgets that can be added and resized on their home screens.Android Auto: Enhanced Experience with Video SupportAndroid Auto is receiving a significant refresh with more personalization options, widgets, and an edge-to-edge interface adaptable to various screen shapes. Media apps like YouTube Music and Spotify are being redesigned for easier in-car use. Notably, Android Auto will support 60fps full HD video playback on YouTube in supported cars later this year, with BMW, Ford, Genesis, Hyundai, Kia, Mahindra, Mercedes-Benz, Renault, Škoda, Tata, and Volvo among the first manufacturers to implement this feature.Gemini Intelligence Expands Across Android EcosystemGoogle is broadening Gemini's presence across its platforms, with the assistant now capable of performing multistep functions across apps. Users can take a photo of an event flyer and ask Gemini to find that event on booking sites, or invoke the assistant with a grocery list to build a cart in their preferred shopping app. Gemini is also coming to Chrome on Android, allowing users to summarize content and ask questions about webpages, with an experimental auto-browse feature capable of completing tasks like booking tickets.Enhanced Security and Privacy FeaturesGoogle is expanding its default-on theft protections to all Android users globally. These features, including Remote Lock and Theft Detection Lock, will be enabled by default on new Android 17 devices, freshly reset devices, or those upgraded to the latest OS. The company is also reducing the number of PIN/password guess attempts a thief can make and increasing wait times between failed attempts. Additionally, Pixel users with Advanced Protection Mode now have access to Intrusion Logging to investigate suspected spyware attacks.The Future of Android: Seamless Integration and AI AssistanceGoogle's announcements signal a future where AI seamlessly integrates into daily tasks across devices. The company is working to break down barriers between platforms, with Quick Share expanding to work with iPhones from various manufacturers and a new iOS-to-Android transfer feature allowing users to import passwords, photos, messages, and more. The introduction of features like Rambler in Gboard, which converts speech to cleaned-up text by removing filler words, demonstrates Google's commitment to natural interaction with technology.

The Lead: Google's Android AI RevolutionGoogle announced a significant upgrade to its Android operating system at the "Android Show: I/O Edition" event, introducing new Gemini Intelligence-branded AI features that transform how users interact with their devices. These innovations include agentic AI capabilities that can complete complex, multi-step tasks across different apps, as well as a novel "vibe coding" feature that allows users to create custom widgets using natural language descriptions.The Event Details: Agentic AI Capabilities ExpandGoogle's new agentic AI features represent a significant leap forward for digital assistants. The system can now handle multistep processes like copying a grocery list from notes and adding items to a shopping cart. Users activate these features by pressing the phone's power button and describing the task they want to accomplish, with the phone's screen providing context for the assistant. Notably, Gemini will wait for final confirmation before completing actions like checkout, ensuring user control throughout the process.The company had previously introduced some agentic capabilities at the Samsung Galaxy S26 launch, including the ability to book a front-row bike for a spin class or find a class syllabus in Gmail and then search for related books. These capabilities have now been expanded to handle more complex, cross-application workflows.The Data Analysis: Market Expansion TimelineGoogle has provided a clear rollout timeline for these new features. The agentic AI capabilities and vibe-coded widgets will first become available on the latest Samsung Galaxy and Google Pixel devices this summer. The company plans to expand these features to other Android devices later in the year, indicating a phased approach to market penetration.Additionally, specific features like Gemini in Chrome will arrive in late June, allowing users to summarize webpage content or ask questions about online material. This mirrors the functionality already available on desktop versions of Chrome with Gemini integration.The Impact Analysis: Redefining User InteractionThese developments mark a fundamental shift in how users interact with their mobile devices. By enabling AI to understand and execute multi-step processes across different applications, Google is moving beyond simple task completion to creating a more seamless, intelligent user experience. This could potentially reduce the cognitive load on users by automating complex workflows that previously required manual intervention across multiple apps.The introduction of "vibe coding" for widget creation represents another significant innovation. By allowing users to describe widgets in natural language, Google is lowering the barrier to customization and making personalization more accessible to non-technical users. This approach mirrors similar efforts by other companies like Nothing, which released a similar tool last year, but Google's implementation is deeply integrated into the Android ecosystem.The Prediction: The Future of AI on AndroidAs these AI capabilities become more sophisticated and widespread, we can expect to see a fundamental transformation of the Android user experience. The line between applications may continue to blur as AI increasingly manages interactions between different services. This could lead to new opportunities for developers to create more specialized tools that work in concert with Google's agentic AI.Google's commitment to following its Material 3 expressive design language across these AI features suggests a cohesive vision for the future of Android aesthetics. As competition in the AI space intensifies, these innovations may set a new standard for what users expect from their mobile devices, potentially accelerating the adoption of AI-powered personal assistants across the industry.

The Lead: Anthropic's Legal AI Expansion Anthropic announced Tuesday that it is launching a host of new chatbot features designed to provide automated assistance to law firms. The new features expand Claude for Legal — the law-focused offering that launched earlier this year — offering users a new set of legal plugins and MCP connectors designed for specific areas of law. The Event Details: New Legal Plugins and Connectors Anthropic's new tools are designed to help law firms automate specific clerical functions — things like document search and review, case law resources, deposition prep, document drafting, and other related areas. The plugins — which represent a bundle of functions and automated tools — are designed to work across legal fields like commercial, privacy, corporate, employment, product, and AI governance. Anthropic is also offering a number of model context protocol connectors. MCPs connect specific data sources and third-party systems to AI models, allowing the models to interact with them directly. In this case, the new MCP connectors integrate Claude into a variety of software applications that are already routinely used by law firms — applications for document management like DocuSign and file search platforms like Box. Legal research sites like Thomson Reuters (which operates Westlaw) can also be connected. The Data Analysis: Funding Surge in Legal AI The new tools come amid hot competition in the legal AI space. In March, the AI law startup Harvey, which uses agentic AI to automate legal workflows, raised $200 million at a valuation of $11 billion. Last month, a rival startup, Legora, raised a $600 million series D, and launched a high-profile ad campaign featuring Jude Law. Legora offers similar services to Harvey — automated solutions built to simplify the often byzantine law processes that have traditionally involved entire teams of humans. The Impact Analysis: Transforming the Legal Profession As AI companies have sought to court law firms, AI-related failures have caused real problems in court. Dozens of lawyers have been caught using AI to generate error-ridden legal documents, as has at least one major law firm. Last year, California issued a first-of-its-kind fine against an attorney who had used ChatGPT to draft an appeal riddled with fake quotes. Federal judges have also been caught using it to draft rulings, a trend that drew the scrutiny of Congressional leaders last year. Meanwhile, AI-generated lawsuits are said to be clogging the arteries of justice — overwhelming courts with stacks of bizarrely argued legal "slop." Despite these challenges, the legal sector is facing mounting pressure to adopt AI, and the firms and in-house teams that move are pulling ahead fast. The Prediction: Future of AI in Legal Services "Claude is making a deeper push into knowledge work, with the legal sector emerging as one of its most significant and fastest-growing industries," a spokesperson for Anthropic said. As the competition intensifies and AI capabilities improve, we can expect to see more specialized legal AI tools that address specific practice areas while mitigating the risks of errors and misinformation. The integration of AI into legal workflows appears inevitable, but the pace and manner of adoption will likely vary across different types of legal practices and firms.

The Devastating Impact on Lebanese Education Israel's war in Lebanon has created a 'lost generation' of students, widening societal disparities and damaging national unity, experts have warned. The conflict has destroyed schools across southern Lebanon and displaced hundreds of thousands of students, with many educational institutions turned into makeshift shelters for displaced people. The Scale of the Crisis According to UNESCO, 339 schools are located in warzones in Lebanon, while hundreds more are acting as collective shelters, affecting access to education for another 250,000 children. Since March, Israeli attacks have displaced more than 1.2 million people in Lebanon, including 500,000 school-aged children. The Shift to Online Learning Some schools have turned to online learning, but experts say this has its drawbacks, particularly for students from lower-income families. Limited internet access, electricity shortages, and lack of devices have hindered students' ability to access education. The Long-Term Consequences Experts warn that the crisis will have long-term consequences, including increased inequalities, child labor, and child marriage. The economic crisis in Lebanon has already led to a significant erosion of the middle class, with the country's Gini coefficient rising from 0.32 in 2011 to 0.61 in 2023. The Need for Urgent Intervention Experts stress the need for urgent and sustained intervention to address the crisis, including out-of-the-box thinking to support students and teachers. The fear is that without serious nationwide intervention, these disparities will have long-term consequences and leave an entire generation further behind.

The Incident A lorry has become stuck in a sinkhole on a rural road in Somerset after being sent to fix it. Contractors from a company called Stabilised Pavements were sent to fix holes on Butleigh Drove, near Walton, when the ground gave way. The Lorry's Condition The lorry was left stuck at a near 45-degree angle, forcing the workers to abandon it. A council spokesperson said the lorry was due to be recovered. The Road Network Concerns Lucy Trimmell, an opposition councillor in Somerset, told the Times the council’s approach to road repairs was like “trying to darn a pair of fishnet tights” and the road network was “rapidly deteriorating”. Richard Wilkins, the portfolio holder for transport and waste services, said council contractors had been working to fix the damage caused by Storm Chandra in January, as well as other weather events. The Council's Response A spokesperson for Somerset council said: “Planned highway works are taking place on Butleigh Moor Drove (also known as Butleigh Drove) near Walton, and these works are being delivered by contractors. The road is constructed on peat and has experienced significant movement and rutting. Issues of this nature can occasionally arise when carrying out works in these conditions. A lorry involved in the works is due to be recovered. The site will then be assessed to determine the most appropriate approach to complete the repairs.”

The Return of a ChampionAndy Murray will make his return to tennis as part of Jack Draper's interim coaching team during the grass-court season, marking a significant comeback for the former world No. 1. The partnership comes as Draper begins his comeback from a recent knee injury that forced him to miss the entire clay-court season, including the French Open.Draper's Coaching ShuffleDraper has parted ways with Jamie Delgado after working together for just six months. The pair linked up at only four ATP tournaments this year due to Draper's persistent injuries. "I am very grateful for everything Jamie Delgado has done for me over these past six months," said Draper in a statement. "He is a world-class coach and a great man." In the interim, Draper will continue to be supported by the LTA team, with the addition of Andy Murray, who will be supporting him throughout the grass-court season.The Injury-Plagued JourneyHaving reached a career high ranking of world No. 4 last season, Draper has endured a difficult 12 months due to a series of significant injuries. After returning from a bone bruise to his playing arm that forced him off the tour for around seven months, the 24-year-old suffered a knee injury in April at the Barcelona Open. This latest injury has caused him to withdraw from the entire clay-court season. He is scheduled to return at the start of the grass-court season.Strategic PartnershipThis will be Murray's second coaching job since retiring from professional tennis in 2024. He previously enjoyed a highly publicized six-month stint with Novak Djokovic, his biggest rival during his playing career, in the first half of last year. Murray's addition to Draper's team brings a wealth of Grand Slam experience, having won the men's singles title at Wimbledon in 2013 and 2016.Wimbledon AmbitionsFor Draper, who has never previously reached further than the second round at Wimbledon, Murray's presence could provide the tactical insight needed to navigate the prestigious tournament. The grass-court season represents a crucial opportunity for Draper to build on his career-best form and potentially make a deep run at Wimbledon, where Murray's expertise could prove invaluable.

The Skyboxification of FootballIn What Money Can't Buy, his 2012 critique of a world where everything is for sale, Michael Sandel laments what he calls "the skyboxification of American life". Price gouging and profiteering, Mr Sandel notes, can exclude millions from communal experiences that should unite people, rather than divide them according to the size of their wallets. That is "not good for democracy, nor is it a satisfying way to live".World Cup Ticket Pricing Strategy Under FireAhead of the men's World Cup in the United States, Canada and Mexico next month, millions of football fans would readily agree with the Harvard philosopher. Gianni Infantino, the president of the sport's global governing body, Fifa, has predicted that this summer's tournament will be the "greatest and most inclusive … ever". But the lead-up has been overshadowed by a ticketing strategy that is almost surreally indifferent to the battered traditions of "the people's game".Exorbitant Price Points RevealedIn the latest phase of an opaque, manipulative process, Fifa has tripled the price of some of the best seats for the World Cup final in New Jersey to $32,970 (for the 2022 final in Qatar, top whack was about $1,600). On Fifa's Resale/Exchange Marketplace, tickets for the final have ranged from $8,970 to a laughable $11,499,998.85. For the US's opening group game against Paraguay in Los Angeles, the cheapest tickets initially offered were priced at $1,200. Even Donald Trump worried that might be too much for ordinary Americans to afford.Dynamic Pricing and Financial BarriersA dynamic pricing system means that a few tickets may become cheaper closer to the tournament. Many are likely to become still more expensive. These are ridiculous, exploitative prices that undermine the integrity of the world's most avidly followed sporting event. To add insult to financial injury, fans who bought early at prohibitive cost are discovering that the goalposts have now moved, as seats with the best views are hived off for even more lucrative hospitality packages.Impact on Football's Democratic TraditionFactor in accommodation and transport costs for travelling fans, and it is clear that access to the most monetised World Cup in history has been priced way beyond the means of most football lovers. But Mr Infantino has remained blithely dismissive in the face of the groundswell of protest, noting merely that the competition is being staged in a "market in which entertainment is the most developed in the world. So we have to apply market rates."Market Rates vs Democratic ValuesThis is self-serving nonsense. It is difficult to take anything Fifa's president says seriously after his decision to award a peace prize to Mr Trump. But such words betray a dismaying inability to consider wider responsibilities beyond a dollar-denominated bottom line. The best World Cups have been sporting and cultural festivals, enriched by the presence of passionate supporters from host cities and around the world. Only those with impressively deep pockets will be able to maintain that tradition in June and July.The Future of Inclusive FootballIn his book, Mr Sandel writes: "The more things money can buy, the fewer the occasions when people from different walks of life encounter each other." Next month, Mr Infantino will no doubt be waxing lyrical about the ability of the World Cup to bring people together and cross divides. Pious talk of inclusivity will ring very hollow if only the well-off can enter a stadium to actually watch a game.