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Jasveen Sangha, a 42-year-old woman, has been sentenced to 15 years in prison for her role in supplying illegal drugs to Matthew Perry, the actor from the popular TV show Friends. Perry died from the 'acute effects of ketamine' in 2023.In a court appearance, Sangha expressed regret for her actions, stating, 'I take full responsibility for my actions. These were horrible choices that ultimately proved tragic.'Sangha pleaded guilty to five felony drug counts linked to Perry's death, including distributing ketamine resulting in death. Her defence lawyers had requested a sentence limited to time already served, but District Judge Sherilyn Garnett handed down a harsher sentence, citing Sangha's continued sale of ketamine after Perry's death as a lack of remorse.Perry had struggled with substance abuse and prescription painkillers, sharing his experiences in his memoir, Friends, Lovers, and the Big Terrible Thing. Federal officials reported that Perry became addicted to ketamine during infusions at a clinic, and when doctors declined to increase his dosage, he turned to alternative sources.Sangha, referred to as the 'Ketamine Queen', admitted to selling 51 vials of ketamine to a go-between, who then sold them to Perry through his personal assistant. Prosecutors stated that this led to Perry's death from ketamine overdose.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

Health‑service workers have voiced strong unease after it emerged that engineers from the controversial US tech firm Palantir were issued NHS.net email accounts. Those accounts unlock a directory containing contact details for as many as 1.5 million NHS staff members, as well as access to SharePoint file‑sharing and Microsoft Teams groups used by the service. Palantir’s engineers are supporting the rollout of the Federated Data Platform (FDP), a £300 million contract awarded in 2023 to link patient records across disparate NHS systems. The government touts FDP as a cornerstone of its plan to "reinvent the NHS" by moving from analogue to digital, promising faster diagnoses, better appointment allocation and more personalised treatment. While the use of NHS email accounts by external suppliers is not unprecedented, Palantir’s reputation for AI‑driven surveillance and military‑grade technology has amplified staff, patient and human‑rights concerns. Rory Gibson, a resident doctor, warned that his personal contact details should not be accessible to a company that also works on drone‑strike systems. The Guardian has identified at least six Palantir engineers who have been given NHS.net credentials. In response, a Palantir spokesperson argued that such access is "normal practice for government suppliers" and cited official guidance that government systems are more secure than external alternatives. Palantir claims its software has already yielded measurable benefits: 110,000 additional operations, a 15.3% reduction in discharge delays and a 6.8% rise in cancer diagnoses within 28 days of referral. The company stresses that it merely provides software, with data usage remaining under NHS control and subject to strict contractual confidentiality. David Rowland, director of the Centre for Health and the Public Interest, acknowledged that granting NHS email addresses may not breach rules but highlighted the "deep ethical concerns" that Palantir’s profit‑driven model clashes with NHS values. He called for a comprehensive review of which private firms receive public‑sector funding. Some NHS staff reported being placed in virtual Teams meetings with Palantir personnel who joined using NHS credentials, without any disclosure of their employer – a practice that further eroded trust. Under the NHSmail access policy, "independent sector organisations" delivering health and social‑care services nationally may use NHSmail. An unrestricted NHS.net account can reveal staff roles, locations, workplace details and even grant access to commercial "Blue Light" discounts. Palantir’s technology is already deployed by UK police forces and the Ministry of Defence, prompting critics to warn that its "drag‑and‑drop" interoperability could facilitate state overreach, including a potential British analogue of the US Immigration and Customs Enforcement agency. The firm’s founders include US businessman and former Trump supporter Peter Thiel and CEO Alex Karp, both known for advocating aggressive surveillance tools. Its UK arm is led by Louis Mosley, grandson of historic British fascist leader Oswald Mosley. An NHS spokesperson reiterated that all suppliers, including Palantir, operate strictly under NHS instruction, with data access governed by robust contractual confidentiality obligations.

Tens of thousands of people have been hired by Scale AI – a firm 49% owned by Meta – to train artificial‑intelligence models by scraping Instagram accounts, harvesting copyrighted artwork and transcribing pornographic soundtracks, according to the Guardian.Scale AI promotes its Outlier platform as a flexible, expert‑driven marketplace, recruiting professionals from medicine, physics and economics to "become the expert that AI learns from."Workers, however, say the reality diverges sharply from high‑level model refinement. They describe tasks that involve massive personal‑data scraping and content that many find morally uncomfortable.Outlier is managed by Scale AI, which holds contracts with the U.S. Pentagon and other defense companies. Its chief executive, Alexandr Wang, is hailed by Forbes as the world’s youngest self‑made billionaire, while former managing director Michael Kratsios served as science adviser to former President Donald Trump.One contractor noted that users of Meta platforms would be shocked to learn their photos and friends’ images are being harvested for AI training, with workers manually reviewing profiles to extract data.The Guardian interviewed ten Outlier contributors – many also journalists, graduate students, teachers or librarians – who took the gig work out of economic desperation. One said, "A lot of us were really desperate" and felt compelled to accept the unstable, low‑pay assignments.These gig workers, dubbed “taskers,” often feel they are training their own replacements, expressing “internalised shame and guilt” over contributing to the automation of creative professions.Law firm Clarkson, representing AI gig workers, estimates that hundreds of thousands of people worldwide now labor on platforms like Outlier. Taskers report bait‑and‑switch recruitment tactics, where advertised high salaries are replaced by lower‑paid projects after onboarding.All contributors are monitored through a tool called Hubstaff, which can screenshot browsers to verify work. While Scale AI claims the software is only for accurate payment, workers describe it as constant surveillance.Assignments have ranged from transcribing pornographic audio and labeling photos of dead animals or dog faeces, to annotating diagrams of infant genitalia and violent police scenarios. One doctoral student recounted being promised “no nudity” only to receive explicit porn clips.Scale AI says it shuts down any task flagged as inappropriate and does not accept projects involving child sexual‑abuse material or pornography, though workers note that publicly available images of minors have been used for training.Social‑media scraping tasks required workers to tag individuals by name, location and age, sometimes pulling data from accounts of users under 18. One task asked contributors to order Facebook photos by the subject’s age, prompting ethical unease.In addition to personal data, taskers were asked to harvest copyrighted artwork, with strict instructions to avoid AI‑generated images and select only hand‑drawn pieces. Scale AI maintains it does not ask workers to violate copyright standards.Scale AI’s client list includes major tech firms such as Google, Meta and OpenAI, as well as the U.S. Department of Defense and the government of Qatar, highlighting the growing demand for labelled data as AI models scale.Some workers reported interacting with ChatGPT and Claude, and speculated they might be training Meta’s upcoming model, code‑named “Avocado.”OpenAI announced it ended its partnership with Scale AI in June 2025, citing its supplier code of conduct that mandates ethical treatment of all workers.Despite irregular pay, occasional mass layoffs and the unsettling nature of many tasks, many taskers remain on the Outlier platform, hoping the AI future will eventually improve conditions. One said, "I have to be positive about AI because the alternative is not great."In response, a Scale AI spokesperson stated, "Outlier provides flexible, project‑based work with transparent pay. Contributors choose when and how they participate, and we regularly hear from highly skilled contributors who value the flexibility and opportunity to apply their expertise on the platform."

On Halloween night in 2022, the 33‑year‑old Los Angeles‑based musician Angelo De Augustine collapsed at home, experiencing a cascade of sensory failures that left him unable to see, hear or move properly. Family members rushed him to the hospital, where doctors ran extensive tests but could not pinpoint a diagnosis, ultimately sending him home with a warning to return only if he became completely deaf or blind. Faced with a semi‑incapacitated body, De Augustine’s sole focus became completing the album he had been crafting for the previous year, Toil and Trouble. He admits he believed he might not survive the illness, yet he pushed through the pain, hoping to finish the record before his presumed death. De Augustine’s career had been gaining momentum. After his 2014 debut Spirals of Silence, he joined Sufjan Stevens’ label Asthmatic Kitty for 2017’s Swim Inside the Moon and later co‑produced the acclaimed 2021 collaboration A Beginner’s Mind. A 2019 track, “Time,” from the album Tomb, amassed over 31 million streams after featuring in Zach Braff’s film A Good Person, but the artist was too ill to capitalize on its success. Recovery was gradual and arduous. Over three years De Augustine relearned basic functions—walking, speaking, hearing, and playing instruments. Those challenges informed his newest work, Angel in Plainclothes, an album that contemplates mortality and the fleeting nature of life through ethereal soundscapes. Musically, the record draws on influences ranging from Nick Drake’s wistfulness to early Paul Simon’s lyricism. Tracks such as “Spirit of the Unknown” celebrate simple joys, while the lead single “Mirror Mirror” uses a reflective metaphor to describe his feeling of being a ghost watching life from the sidelines. He records from a studio he calls “A Secret Place,” emphasizing the intimate, introspective tone of the project. Recent research, De Augustine notes, suggests that chronic stress can overload the central nervous system, causing the body to shut down—a possible explanation for his 2022 episode. He points to the relentless pressures of the music industry as a likely source of that prolonged anxiety. Born to musical parents—his mother Wendy Fraser sang on the Dirty Dancing soundtrack—De Augustine originally pursued soccer before injuries redirected him toward music. Largely self‑taught, he began writing original material without formal lessons, a factor he believes gives his songs a distinctive edge. During his convalescence he moved back in with his mother, unable even to prepare meals. A breakthrough came when he discovered that immersion in water alleviated his symptoms, prompting a deeper awareness of his stress levels. A disciplined regimen of physical and mental exercises helped rewire his nervous system, gradually restoring his ability to play guitar and sing. When his health permitted, De Augustine returned to the studio, this time enlisting collaborators such as string arranger Oliver Hill, harpist Leng Bian, producer Thomas Bartlett (aka Doveman), and his mother on percussion. Drummer Jonathan Wilson contributed drums and offered his Topanga Canyon studio for the track “The Cure,” a song that likens illness to addiction. The album’s sonic palette is enriched by antique instruments—a bowed psaltery, aquarion, Marxophone, bass recorder, train whistle, 1960s German guitaret, miniature accordion, and a 1990s synthesiser version of a Japanese koto harp—underscoring De Augustine’s penchant for unconventional textures. After a five‑year hiatus from live performance, he returned to the stage last year, describing the experience as “amazing” despite its challenges. Though he acknowledges he is not yet fully healed, he feels he is emerging as a blend of his former self and a newly humbled individual who no longer takes life for granted. Reflecting on his journey, De Augustine says, “For so long my only focus was to be a great songwriter, and perhaps I paid the price for that. Now I’m trying to live a good life rather than chase outcomes.” Angel in Plainclothes was released via Asthmatic Kitty on 24 April, offering listeners a glimpse into his renewed perspective and artistic resilience.

Effective September, the UK will limit interest on Plan 2 and Plan 3 student loans to 6%, announced by ministers amid growing concerns that higher inflation could push repayments sharply higher for graduates.Currently, borrowers on Plan 2 pay an interest rate equal to the Retail Prices Index (RPI) – presently 3% – plus up to an additional 3% once they earn more than £29,385. While studying, both Plan 2 and Plan 3 loans already attract RPI + 3%.Plan 2 loans cover undergraduate courses and Postgraduate Certificates of Education taken out since 1 September 2012 in Wales and between that date and 31 July 2023 in England. Plan 3 loans apply to postgraduate master’s or doctoral programmes for borrowers in England and Wales.Skills Minister Jacqui Smith linked the decision to global instability, noting that “the conflict in the Middle East is causing anxiety at home… Capping the maximum interest rate will provide immediate protection for borrowers, supporting those most exposed within this already unfair system.”The repayment threshold will remain frozen at £29,385 for the next three years, until 2030, a policy that could raise annual repayments by up to £300 for many graduates.Labour MPs have pressed the government to reconsider this freeze, arguing it will erode real‑term earnings as the threshold approaches the minimum wage by 2030.National Union of Students president Amira Campbell welcomed the cap as “a huge win” for the more than 5 million people on Plan 2 loans, but warned that “the change cannot come alone” and called for a rise in the repayment threshold in line with incomes.Prime Minister Keir Starmer has pledged to explore ways to make the student‑loan system fairer, echoing criticism from Conservative leader Kemi Badenoch, who described the scheme as a “debt trap” at “breaking point”.

Majdi Aslan, a 54‑year‑old WHO driver, was killed on Monday when Israeli troops opened fire on a vehicle carrying World Health Organization staff in eastern Khan Younis. Several other passengers, including a WHO doctor, sustained injuries.The incident occurred near the so‑called yellow line on Salah al‑Din Street, an area that has seen near‑daily Israeli strikes since a fragile ceasefire was brokered in October. Gaza’s Health Ministry reports that more than 700 Palestinians have been killed in the renewed wave of violence.According to Al Jazeera correspondent Hani Mahmoud, Israeli forces fired indiscriminately at people and vehicles traveling along the road. A civilian commercial vehicle was followed by a car transporting WHO personnel; the WHO driver was hit in the head and later pronounced dead at Al‑Aqsa Hospital, while roughly seven others were wounded.WHO did not immediately confirm the victim’s employment but issued a statement saying a “critical security incident” had occurred and that medical evacuations from Gaza via the Rafah crossing were suspended with immediate effect. The organization has been coordinating limited patient transfers through Rafah since the crossing reopened earlier this year.The suspension comes as Israel continues to restrict humanitarian aid entry and has repeatedly closed the Rafah crossing, especially as the broader U.S.–Israel conflict with Iran draws international focus. The halt threatens the already strained access to life‑saving treatment for thousands of injured Palestinians.Elsewhere on Monday, a Palestinian man with special needs was killed by Israeli soldiers in southern Khan Younis, a drone strike in Gaza City claimed a 36‑year‑old civilian, and two more Palestinians died in drone attacks on the Yarmouk and Shujayea neighborhoods. Hospital sources say eight Palestinians have been killed by Israeli air strikes outside areas under Israeli control since Sunday.

Duncan James from Blue has opened up about his favorite songs, sharing a personal playlist that reveals a lot about his musical tastes and experiences. The song he inexplicably knows all the lyrics to is Can't Help Falling in Love by Elvis, which he even sent as his audition tape to join Blue.James also shared his go-to karaoke song, It's Raining Men by Geri Halliwell, which he sang at his 30th birthday party. Interestingly, Geri Halliwell herself walked in during the performance and joined James' mum on stage.Other notable songs on his playlist include Sadeness (Part I) by Enigma, his first single purchase, which his friend bought for him at Woolworths. James also confessed that Fantasy Island by Tight Fit was the first song he fell in love with, likely due to his crush on a guy in a zebra print headband from the music video.James also talked about the song that makes him cry, My Life Is Going On by Cecilia Krull, from the Spanish Netflix series La Casa De Papel (Money Heist). On a lighter note, he shared his least favorite song to have sex to, One Love by Blue, which he found creepy.The song that changed James' life was All Rise, which became a worldwide hit and started Bluemania. He also revealed his favorite song to play at a party, Defying Gravity from Wicked, which gets him dancing on tables.On a more sentimental note, James shared the song he can no longer listen to, Meu Abrigo (My Shelter) by Melim, which reminds him of his ex. He also confessed to secretly liking Doctor Jones by Aqua, despite pretending to hate it. Finally, the song he'd like played at his funeral is Bohemian Rhapsody by Queen, which he believes is one of the greatest songs ever written.

Doctors Without Borders (MSF) has condemned a drone strike that hit Al Jabalain Hospital in Sudan’s White Nile State, killing 10 people, among them seven medical staff members. The attack, which struck an operating theatre and a maternity ward, occurred during a children’s immunisation campaign, heightening the humanitarian outcry.MSF’s Sudan emergencies chief, Esperanza Santos, said the assault was “unacceptable” and noted that several of the deceased had previously worked with the organisation. She added that the strike represents a grave violation of medical neutrality.While the perpetrators have not been officially confirmed, MSF’s statement attributes the strike to the paramilitary Rapid Support Forces (RSF), a claim echoed by Sudanese officials. On Friday, Khalid Aleisir, Sudan’s minister of culture, information, antiquities and tourism, called for the RSF to be designated a terrorist organisation and for its members to face prosecution.The incident follows a series of attacks on Sudan’s health infrastructure since the war erupted in April 2023. In a separate incident the same day, a medical supply depot in Rabak, the capital of White Nile State, was also hit. According to the World Health Organization, more than 200 attacks have targeted health facilities since the conflict began, underscoring a systematic pattern of violence against civilians.Local rights group Emergency Lawyers highlighted that recurring drone strikes across South Kordofan, Blue Nile, and the Darfur regions have displaced thousands, further straining an already fragile health system. The Sudan Doctors Network described the Al Jabalain strike as a “deliberate assault on health facilities and unarmed civilians,” warning that such actions exacerbate the nation’s deteriorating medical capacity.International observers note that the targeting of hospitals not only violates international humanitarian law but also hampers efforts to control disease outbreaks and provide essential care to vulnerable populations. The growing body of evidence may prompt renewed calls for accountability and stronger protective measures for health workers in conflict zones.