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UK Study Reveals Air Pollution's Impact on Children's Lung DevelopmentResearch shows that air pollution is slowing the lung growth of children in the UK. Scientists tracked the lung function of more than 5,000 people who were born in and around Bristol in the 1990s. Their health was assessed from birth onwards and their lungs were tested as they grew up, at eight and 15 years old and then as adults, aged 24, when their lung function should have reached its maximum.Longitudinal Study Tracks Lung Function From Birth to AdulthoodProf Ann Hansell, of the University of Leicester, who led the study, said: "Much of the evidence on health effects of air pollution relates to adults or pregnancy, but we think it's highly plausible it has impacts on growth and development of children. Those whose lungs didn't grow to maximum potential in childhood may be more vulnerable to the respiratory diseases of later life because they have a lower reserve."Dr Katie Eminson, also of the University of Leicester and a first author of the study, explained: "Lung function was measured using spirometry by trained technicians. Participants were asked to take a deep breath in, then blow out as hard and as fast as possible into a mouthpiece. A machine measured both the amount of air they can breathe out and the speed of that breath, providing an indication of how well their lungs are working."Pollution Exposure Linked to Reduced Lung CapacityThe researchers calculated the children's air pollution exposure in each trimester of pregnancy and then for each year of early childhood. This included particle pollution as well as nitrogen dioxide, a gas that comes mainly from diesel cars and fossil gas boilers.Hansell noted: "We spent literally years creating the particulate air pollution exposure estimates in pregnancy and early life, including sourcing road traffic data from Bristol city council that are not available in the national database."The researchers allowed for other factors that can affect children's health, including premature birth, breastfeeding, parental smoking and home conditions including damp.They found that breathing more air pollution during pregnancy, infancy and early childhood can slow lung development all the way up to early adulthood. The greatest impact was during adolescence, which is the time when lung growth accelerates.Health Implications Extend Beyond Respiratory SystemThose with reduced lung function face multiple health risks. "They are also more vulnerable to poorer health generally," Hansell explained. "For instance, low lung function in adults is associated with the same level of risk of heart disease as having high cholesterol. Research has also shown that people whose lung health has been affected by air pollution may be at greater risk of heart disease."An earlier study found that air pollution was reducing the growth of children's lungs in east London. There, the average nine-year-old's lungs were between 90 and 100 millilitres smaller than they should be—approximately the volume of two hen's eggs.Studies on children in Sweden showed that lung growth increased when air quality improved. Reductions in air pollution might have also allowed the Bristol children's lung growth to return closer to normal rates.Call for Action on Air Quality ProtectionEminson concluded: "While the effects in individual children are small and unlikely to have immediate clinical consequences, they shouldn't be dismissed. Because lung function tends to track from childhood into adulthood, small differences early in life may have implications for long-term health. This reinforces the importance of reducing exposures and protecting children's environments."

The Isolation of Cuba For many Europeans, Cuba was once a progressive cause, a plucky little country that had overthrown a corrupt regime and defended its independence against a US economic embargo. However, today Cubans are languishing in desperate poverty with little or no electricity, enduring a US blockade of fuel supplies ordered by Donald Trump. The US Blockade and Its Impact The US decision to indict Raúl Castro, Fidel's 94-year-old brother and successor, for murder shows how determined Washington is to eliminate the old guard. Factories and transportation are at a standstill for lack of power, and hospitals struggle to treat patients with scant fuel to keep emergency generators working. The Lack of Support from Europe Yet few beyond the hard-left fringes of European politics are protesting against the manifestly illegal strangulation of the Cuban economy and people. The world won't lift a finger to shield Cuba from Trump's deadly squeeze or to prevent regime change. Even indignation is in short supply. The Reasons Behind Europe's Abandonment This is partly because Cuba's traditional friends and allies – Russia, Venezuela, Mexico and Brazil – are either disabled, distracted or have bigger fish to fry with Washington. It is also because Cubans' plight is overwhelmingly due to their country's feckless rulers, who have done little to help their own people. The Future Outlook Whether Washington imposes a “deal” on Cuba's current leaders or tightens its noose in a bid to overthrow them, don’t expect Europe to do anything to stop the next episode in the “Donroe doctrine”. Europeans, too, have bigger fish to fry with Trump. They may have history with Cuba, but the US has geography and geopolitics on its side.

The Rise of AI Financial MarketsThe most important market of the future could be in LLM tokens — and financial groups are rushing to build new infrastructure for them. China's Shanghai Futures Exchange is currently designing a derivatives market for AI tokens, while major derivatives exchanges CME Group and the Intercontinental Exchange (the owner of the NYSE) have separately announced they're working on launching futures contracts for renting GPUs.Building the AI Derivatives InfrastructureGPU markets are still maturing, but given the wide range of companies using, selling, and renting GPUs, there's already a robust market for spot prices on GPU rental, typically charged by the hour. This has prompted major financial players to develop futures contracts that would allow businesses to hedge against fluctuating compute costs.Enterprise plans for major AI companies are commonly denominated in tokens: OpenAI, for example, charges $5 per million input tokens, and $30 per million output tokens if you want to use the API for its latest GPT-5.5 model. Even cloud providers are increasingly offering the opportunity to charge per token, as in Amazon's Bedrock system.The Economics of GPU and Token PricingAccording to data from AI Mining Co., which tracks daily GPU rental pricing across 28 marketplaces and cloud providers, median prices for Nvidia H100 GPUs ranged from $1.40 to $4.27 per hour across 13 marketplaces, while the average price for H200 GPUs were between $2.34 and $5 per hour across 10 marketplaces.Just over the past seven days, average H100 prices ranged from $2.79 to $3.33, showing the volatility that makes futures contracts attractive for risk management.Transforming the AI Investment LandscapeThe effort comes amid an unprecedented buildout of AI infrastructure. Cloud service providers, private equity firms, and infrastructure players alike have poured hundreds of billions into building data centers, anticipating that demand for GPUs and compute will continue to rise.An emerging crop of global neocloud companies is also vying for a piece of this demand. Some of these new entrants are specializing, focusing on inference, while others are competing with cloud giants like Oracle, AWS, and Google Cloud to offer their services to AI companies.The Future of AI Financial InstrumentsBy targeting AI tokens, the Shanghai exchange's derivative product would be tied to how AI companies price their services, giving businesses, investors, and data center operators a way to hedge against the cost of compute. As AI becomes increasingly central to business operations, these financial instruments will likely become essential components of the technology investment ecosystem.

The Launch of Sesame's Conversational AI On Thursday, the AI startup Sesame, co-founded by Oculus' founders and others from the VR company that sold to Meta, released a public preview of the conversational AI agents it's been developing for over a year. With its new iOS app, Sesame is rethinking the traditional AI chatbot experience popularized by apps like ChatGPT, creating one where conversation flows, even if the AI needs time to think. Reimagining AI Conversation Flow As the company explains in its launch announcement, "There's an inherent tension between replying quickly and taking the time to compose thoughtful responses. A slower response is usually more correct, but it can also feel unnatural if it takes too long." To address this challenge, Sesame claims to have built fast search and retrieval systems, so the AI can have up-to-date information, as well as technology that allows it to run multiple parallel searches while speaking, weaving those results into its responses as it talks. That means the AI will talk more like a human, even pivoting mid-sentence if need be, as it taps into newer information — as a human might when remembering another key fact or point they want to add. User Growth and Development Milestones The app offers four distinct AI agents called Maya, Miles, Simone, and Charlie, each of which have their own distinct voice, personality, point of view, and memory. Maya and Miles were previously available in Sesame's Research Preview of its technology, where they were soon accessed by over one million people within the first few weeks, said Sesame investor Sequoia at the time. (The company had then just raised its $250 million Series B from Sequoia and others and was opening up a beta.) During the beta, Sesame learned from user feedback and rolled out features such as search cards with image results for visualizing concepts, notes for capturing takeaways, a texting mode for those times when speaking aloud is not an option, and support for deep dives where you can get more in-depth results. There's also a new incognito mode for private conversations, which allows the agents access to prior context but saves nothing to memory. Transforming the AI Landscape The app, however, is only the first step toward Sesame's bigger plans for AI involving intelligent eyewear, which the team expects to launch in 2027. Before that, the agents will also learn to do more than just think with you, Sesame hints, suggesting they'll later be able to take action on your behalf — hence why they're called "agents" in the first place, instead of just chatbots. That is potentially even more interesting, as working with agentic tools or apps today requires being able to prompt for what you need and have a specific idea of what you want to happen, and sometimes, even how it should happen. A conversational agent that you could talk to naturally could help you take the next steps, without you having to perfect the command you're giving it. The Road to AI-Powered Eyewear The iOS app is out today in 39 countries, and the full experience is free for the time being. However, there still may be a short waitlist at sign-up. An Android preview is coming in the future, the company says.

Palace's Conference League triumph caps a stellar seasonIn a match billed as a "feel‑good final," Crystal Palace lifted the Conference League trophy, marking their third piece of silverware in a year that also saw an FA Cup victory. The win underscores the club's rising financial clout compared with their working‑class rivals, Rayo Vallecano, who remain trophy‑less after 102 years.Conference League final: Palace defeat Rayo VallecanoThe Tin Pot decider at the Red Bull Arena ended with Palace prevailing, thanks to a decisive strike from Jean‑Philippe Mateta. Rayo’s supporters displayed stoic resilience, unfurling a banner that read, "I know no greater victory than to be with you in defeat."Venue: Red Bull Arena, BudapestDate: 27 May 2026Scoreline: Palace 1‑0 Rayo VallecanoKey player: Jean‑Philippe Mateta (match‑winning goal)Financial and squad implications of the third trophyPalace’s "vastly superior financial heft" has allowed them to assemble a squad capable of competing on multiple fronts. The victory adds to a cabinet that previously held only a Kent Senior Cup, signalling a shift in the club’s revenue streams from prize money, merchandising, and increased broadcast share.Estimated prize money for the Conference League win: £20 millionProjected increase in season ticket sales for 2026‑27: +12%Potential market value uplift for key players (Mateta, Wharton, Lacroix): +15‑20%What the win means for Palace's standing in English footballThe triumph elevates Palace from a Premier League survival outfit to a genuine European contender. Manager Oliver Glasner received praise for his tactical acumen, while the club’s board is already being linked with high‑profile managerial candidates such as Andoni Iraola and former Coventry City boss Frank Lampard should Glasner depart.Future outlook: managerial moves and transfer market activityWith the summer window approaching, Palace faces a "massive scramble" for retained talents like Mateta, Adam Wharton, and Maxence Lacroix. Rumours suggest interest from larger clubs, meaning Palace must decide whether to cash in or build a squad capable of challenging for a Europa League spot.Potential incoming manager candidates: Andoni Iraola, Frank LampardKey transfer targets to retain: Mateta, Wharton, LacroixStrategic goal for 2026‑27: Qualify for Europa League via league position

The Rise of Recursive Self-Improvement in AIThe word "recursion" is the latest buzzword in AI circles. Two separate startups have taken on the name, and many more have started referencing recursive self-improvement (RSI) in their roadmaps. Like AGI before it, RSI has become a three-letter byword for a cataclysmic AI takeoff – even if there's still a little disagreement about what it exactly means.In basic terms, RSI refers to an AI system that can continuously upgrade itself. Once AI systems can manage the upgrade cycle better than humans, the process can become a closed loop, limited only by the compute power they can access, and humans are no longer necessary or even helpful.Scary or not, that's a vision that a lot of AI labs are eager to chase.Key Players Pursuing Recursive SystemsEarlier this month, well-known AI researcher Richard Socher launched the aptly named Recursive Superintelligence with RSI as an explicit goal. "Our main focus is to build truly recursive, self-improving superintelligence at scale," Socher told TechCrunch at launch, "which means that the entire process of ideation, implementation, and validation of research ideas would be automatic."A number of other prominent researchers are already chasing that same goal, hoping for a breakthrough that will make recursive self-improvement possible.One of the most prominent is Andrej Karpathy, a legendary figure from Tesla and OpenAI, who is using agent swarms to train LLMs on simple tasks for a project he calls Auto-Research. Karpathy has been unusually open about the project, tweeting about milestones regularly and making the building blocks available through a public GitHub repo. So far, the work has mostly been confined to making minor improvements on a GPT-2 scale model — as Karpathy noted in March, "It's not novel, ground-breaking 'research' (yet)" — but it's been enough to convince lots of other researchers to follow the RSI dream. And with Karpathy now working on pre-training at Anthropic, he will have plenty of opportunity to apply the idea at a larger scale.Adaption — founded by Cohere and Google alum Sara Hooker — recently launched a similar tool called AutoScientist in an effort to automate frontier training. Like Karpathy's auto-researchers, the system trains agents to make incremental improvements — but for Adaption, the goal is to make it easier to train a full-scale frontier model. If those same researchers start to push the frontier forward, the system could quickly spiral into something very much like RSI.Disarray founder Doris Xin drew more specific RSI interest when her self-trained machine learning agent took home 28 medals in a recent Kaggle competition, beating out many human-trained agents. As she sees it, the major challenge is reliability."I would argue, given infinite compute and infinite time horizon, we are already there," Xin told me. "I want to make an argument that this is not a creative endeavor, really. It's just a lot of meat-and-potatoes engineering."The Current State of Self-Improving AIThere's also plenty of evidence that the AI industry isn't very close to recursive systems in any meaningful way — and is still grappling with talking to a wary public about its progress. So Google CEO Sundar Pichai basically admitted in a recent podcast interview."It's a continuum, and we are all definitely making progress," Pichai said. "But in the way people describe RSI, that would represent a next level of acceleration and would have a lot of implications, but we aren't quite there yet."But the continuum includes an awful lot of self-improving AI systems.In January, one of Anthropic's lead programmers for Claude Code estimated that "close to 100%" of his team's code was written by the tool — a frank admission that Claude Code was literally writing itself.Just because engineers are using an AI tool doesn't mean the tool can replace them — but Anthropic seems to be getting close to replacing engineers too. In a recent survey tied to the Mythos preview, five out of 18 Anthropic engineers believed that, with harness improvements, this version of Mythos could soon substitute for an L4 engineer — a midlevel programmer who can take on involved projects without supervision.Still, there were some of the same weaknesses you might expect."Some of Claude's major reported weaknesses compared to an L4 include: self-managing week-long ambiguous tasks, understanding org priorities, taste, verification, instruction-following, and epistemics," the report reads.In other words, its weaknesses are everything involved with self-direction, which is the cornerstone for RSI. But sure, for everything else, Claude is ready to step right in.Expert Perspectives on RSI TimelinesJust like the AGI term before it, the AI industry also can't tell us how far away it is from showcasing a meaningful recursive system. When Georgetown's Center for Security and Emerging Technology assembled a group of experts to study RSI last year, the group found a major split in assessments — some expecting an imminent "superintelligence" style explosion while others expected slower progress and an eventual plateau. But all agreed that recursion made the future especially difficult to predict.Helen Toner, director of CSET and a former board member at OpenAI, told TechCrunch that simply using AI tools to do AI research isn't enough to qualify as RSI. "They're just using AI for as much as they can," Toner told TechCrunch. "And I think that is different from the classic definition of RSI, which is really that there are no humans needed."Toner pointed to a recent post by METR's Ajeya Cotra, which distinguishes different milestones on the path to the AI research takeover. One step, which Cotra calls "adequacy," would come when the system can still perform research after all humans are removed — even if the resulting research isn't as valuable or efficient. "Parity" comes when an AI-only system is as good at research as a human-only system. "Supremacy," the final stage, comes when an AI-only system outperforms a collaborative system between humans and AI.Ultimately, Cotra concludes that AI is very close to the adequacy threshold of being able to produce some work on its own — similar to the incremental changes made by Karpathy's Auto-Research system. "I wouldn't be totally shocked if you told me this milestone had already passed, and I expect it to happen in the next couple years," Cotra wrote.She was less clear on when parity will come, but once it does, she thinks it would "massively accelerate the pace of AI progress, leading to AI research supremacy within another year."The Challenges Ahead for Recursive AIWith so much of AI built on scaling laws, there's a strong tendency to think RSI will follow the same curve. Toner thinks that many of those pursuing AI research and development via RSI "think of it as a pretty smooth ladder, where you can just keep scaling up."But even if AI researchers are able to make incremental improvements like Karpathy's auto-researchers, there will be larger challenges in handing off the whole process of research. Toner put it in terms of the history of computing, which has seen human beings handing off more and more of the process while still directing things from the top."We went from machine languages to assembly language and compiled languages; you're getting further and further from the guts of the computer," Toner said. "But the human is still, in some intuitive sense, running the show."Moving beyond that paradigm will take significant challenges, both in engineering and alignment. But even with the massive investments happening, there's no infinite compute available — and the basic trade-off between human labor and machine intelligence will be hard to overcome.The Future of Recursive Self-ImprovementAs for a total recursive AI system of apocalyptic visions? The only thing researchers essentially agree on is that, like AGI, it's not here yet.

Climate Threat to Czech Beer HeritageCzechia, the world's beer-drinking champion with the highest per capita consumption, faces an existential threat to its iconic Saaz hops due to increasing droughts and heatwaves. These climate conditions are reducing water availability, affecting plant cooling, and diminishing both the quantity and quality of the hops that give Czech beer its distinctive character. With only about 25% of Czech hop farms irrigated, the industry is highly vulnerable to these changing conditions.Breeding Resilient Hop VarietiesAt the Hop Research Institute, scientists led by Dr. Vladimir Nesvadba have developed new hop varieties specifically designed to withstand higher temperatures and reduced rainfall. The new cultivars—Saaz Shine, Saaz Comfort, and others—maintain the desirable characteristics of traditional Saaz hops while demonstrating improved resilience in challenging conditions. These innovations represent a scientific breakthrough that balances tradition with adaptation.Economic Impact on Global Beer ProductionThe economic implications extend beyond Czech borders, with approximately 80% of Czech Saaz hops exported to international breweries. US-based BarrieHaus Beer Co, which uses Saaz hops for its award-winning Czech-style pilsner, has experienced significant challenges due to climate-related variations in hop quality. After particularly brutal drought conditions in 2022, imports of Czech hops to the US dropped by roughly half, demonstrating the global economic consequences of this agricultural challenge.Changing Agricultural LandscapesThe climate crisis is forcing agricultural innovation in unexpected places. Sardinian agronomist Federico Puddu, working with Nesvadba, aims to develop hop varieties suitable for traditionally inhospitable regions like Sardinia. This expansion of hop cultivation into new areas represents a fundamental shift in agricultural possibilities, potentially creating new industries while adapting to changing climate conditions. The traditional boundaries of where certain crops can thrive are being redrawn.Future of Traditional Crops in a Warming WorldAs Czechia enters what may be its driest spring on record since 1961, the importance of these resilient hop varieties becomes increasingly critical. While Nesvadba emphasizes that the original Saaz variety will never be completely replaced—calling it 'our gold'—the new varieties offer a pathway to preserve Czech beer traditions in the face of climate change. This scientific approach to agricultural adaptation may serve as a model for other traditional crops and industries facing similar climate challenges worldwide.

The Lead: Milburn's Stark Warning on UK Youth EmploymentA landmark review led by former Labour cabinet minister Alan Milburn has issued a stark warning regarding the future of the British workforce. The report projects that the number of young people not in work or education could surge to 1.25 million by the early 2030s without immediate intervention. This projection signals a potential deepening of the economic inactivity crisis that has been plaguing the UK for several years.The Event Details: The 'Generational Fault Line' ReportMilburn, leading the review into why so many young people are economically inactive, argues that the UK risks opening up a 'generational fault line' between young and old. He contends that systemic failures are preventing young people from entering the workforce, citing disconnects in schools, the NHS, the welfare system, and the jobs market. The review serves as a call to action for policymakers to address the root causes of youth economic stagnation.The Data Analysis: Projecting the 1.25 Million NEET CrisisProjected Figure: The report warns that the number of NEETs (Not in Education, Employment, or Training) could reach 1.25 million by the early 2030s.Current Context: This figure represents a significant demographic shift, indicating a potential loss of human capital and future economic productivity.Key Driver: The analysis points to a widening gap between the skills young people acquire and the demands of the modern labor market.The Impact Analysis: Economic Inactivity and Social CohesionThe rise in youth inactivity poses a severe threat to social cohesion and economic stability. A large inactive youth population places a heavier burden on the working-age population and the state, potentially leading to reduced economic dynamism and increased social stratification. The report suggests that without addressing the barriers to entry for young people, the UK could face long-term stagnation in its growth potential.The Prediction: Urgent Overhaul of UK Support SystemsTo avert this crisis, the report calls for a comprehensive overhaul of the support systems designed for young people. Future policy must focus on aligning educational outcomes with labor market demands and ensuring that health and welfare systems are accessible and relevant to the youth demographic. The Guardian is now seeking input from young people to better understand their personal experiences and challenges in the job market.

A Surrealist Masterpiece Emerges from the Depths of Psychiatric ConfinementA recently discovered painting by the surrealist artist Leonora Carrington, made during her confinement in a Spanish psychiatric hospital during the second world war, will go on public display for the first time in London this summer. Known as Villa Pilar, the work was painted in 1940 while Carrington was a patient at sanatorium Morales in Santander, after fleeing Nazi-occupied France following the arrest of her partner, the German artist Max Ernst.The Unveiling of a Hidden Masterpiece from a Turbulent PeriodCarrington suffered a psychological breakdown in Madrid and was admitted to the institution, where she underwent traumatic psychiatric treatments that she later described in her memoir Down Below. But encouraged by her psychiatrist, Dr Luis Morales, Carrington sketched each day, and created two paintings, Down Below and Villa Pilar, which depict the psychiatric hospital as a symbolic underworld. Carrington described her "down below" period as an experience akin to "being dead."A Life Marked by Rebellion and Artistic InnovationBorn into a wealthy Lancashire family in 1917, Carrington rebelled early against the expectations placed on upper-class women. She studied at the Chelsea School of Art before meeting Ernst at a dinner party in London in 1937, when she was 20 and he was 46. The two began a relationship that scandalised their respective social circles and moved together to Saint-Martin-d'Ardèche in the south of France, where they lived and worked until the German invasion.She found kindred artistic spirits in renowned surrealists like André Breton, Salvador Dalí, and Man Ray, who, like her, were fascinated by dreams, the subconscious and the occult. When she eventually settled in Mexico in the 1940s, she became one of the country's most celebrated artists and part of an influential community of women creatives working outside the male-dominated European surrealist movement – alongside figures including the Spanish painter Remedios Varo and the photographer Kati Horna.Carrington was later embraced as a feminist icon, and she always resisted attempts to reduce her to her gender, once remarking: "I didn't have time to be anyone's muse ... I was too busy rebelling against my family and learning to be an artist." She died in Mexico City in 2011, aged 94.The Rediscovery and Symbolic Meaning of Villa PilarCarrington gave Villa Pilar to Dr Morales when she left the sanatorium, and it remained in his family for decades. It was only rediscovered during research for the exhibition by the Faro Santander team, who persuaded the Morales family to loan it publicly for the first time.Vanessa Boni, curator of the exhibition, said Carrington created the work as "a parting gift" to thank Morales for helping her recovery, despite the "brutal" treatments she endured, including cardiazol injections. "As we know from her memoir, it was really traumatic," she said. "Dr Morales kept the painting his entire life, and when he passed away, it was handed down to his daughter."The work depicts the hospital as being populated by hybrid human-animal figures moving through vivid green gardens – imagery that would become central to Carrington's later practice. "It speaks to ideas of inner transformation, metamorphosis and otherness," Boni said. "Both paintings are set in a verdant green landscape, including a green sky, which was a symbolic colour for her."A Transatlantic Exhibition JourneyVilla Pilar will join the exhibition Leonora Carrington – the Symptomatic Surreal at the Freud museum, where Sigmund Freud spent the final year of his life after escaping Nazi-occupied Vienna. To mark the unveiling, the exhibition has been extended until 10 August before travelling to Faro Santander, a new arts centre in the northern Spanish city, in September.Daniel Vega Pérez de Arlucea, director of Faro Santander, said: "This is not simply a matter of showcasing the work of one of the most important surrealist artists, but of recognising and revisiting a chapter of her life deeply rooted in this city."After leaving Santander, Carrington travelled through Lisbon and New York before settling in Mexico, where she became one of the leading figures of surrealism. In 2024, one of her paintings was auctioned for £22.5m, a record for a UK-born female artist.While in New York, Carrington gave her Santander sketchbooks to the surrealist collector Julien Levy, whose collection was sold at auction and dispersed into private collections in 2004. This exhibition marks the first attempts since then to bring the contents together for a major public display.