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Colombian Voters Head to Polls in First Round of Presidential RacePolls opened across the country for the inaugural round of Colombia’s presidential election, featuring a left‑wing lawmaker, an independent businessman and a right‑wing senator vying to succeed President Gustavo Petro. A heavy security presence and a ban on public alcohol sales aim to keep tensions low. Poll Numbers and Candidate StandingsIvan Cepeda (government‑aligned senator) – 33.4% in the latest CNC poll, currently the frontrunner.Abelardo De La Espriella (businessman) – second place, campaigning on hard‑line security and megaprison projects.Paloma Valencia (senator backed by former President Alvaro Uribe) – third, would become Colombia’s first female president if elected.Fourteen candidates in total are contesting the presidency. If no one surpasses the 50% threshold, the top two will face a runoff on June 21. Implications for Colombia’s Political Landscape and SecurityThe result will gauge the durability of Petro’s left‑wing legacy, including his “Total Peace” negotiations with armed groups. A Cepeda victory could extend Petro’s social‑reform agenda, while a win for De La Espriella or Valencia would likely shift policy toward a tougher security stance, echoing approaches seen in El Salvador.Violence remains a concern; last year candidate Miguel Uribe Turbay was assassinated, underscoring the persistent threat from paramilitaries, drug cartels and rebel factions. What the First Round Results Could Mean for a Run‑offShould the vote fall short of the 50% mark, a June runoff will force the left‑wing and right‑wing blocs to consolidate around a single contender, potentially reshaping alliances. Analysts warn that a fragmented right could coalesce behind a hard‑line candidate, while the left may need to rally behind Cepeda to preserve Petro’s reforms.

Lead: Triumph Over Tragedy on the Streets of North LondonArsenal fans flooded the streets of north London on Sunday, cheering the Premier League title despite a bruising Champions League defeat. Defender Gabriel Magalhães admitted the shoot‑out loss was “painful”, but the club’s open‑top bus parade quickly shifted the narrative to celebration.Open‑Top Bus Parade Turns Celebration into Citywide FestivalThe squad left the Emirates Stadium at 2:15 pm for a 5.6‑mile route that wound through Holloway Road, Highbury, and surrounding neighborhoods. Captain Martin Ødegaard led the first bus, proudly displaying “Champions 25/26” and the Premier League trophy, while the women’s team followed on a third bus with the FIFA Champions Cup.Parade Route, Timing and Crowd EstimatesDeparture: 2:15 pm from Emirates StadiumDistance: 5.6 milesEstimated spectators: hundreds of thousands along the routeKey stops: Holloway Road, Highbury, IslingtonNotable participants: Gabriel Magalhães, Eberechi Eze, Myles Lewis‑Skelly, coaching staff, club officialsCommunity Reaction and Club Momentum After Dual OutcomesLocal businesses, such as the Coffee Zee café on Holloway Road, described the scene as “the most insane I have ever seen”. The parade not only celebrated the league triumph but also served as a morale boost after the Champions League disappointment, with manager Mikel Arteta promising to use the setback as “fuel” for next season.What the Celebration Signals for Arsenal’s Next SeasonPlayers like Myles Lewis‑Skelly expressed optimism, calling the moment “the start of a new era” and pledging to “go and achieve our dreams”. The massive fan turnout and unified club atmosphere suggest a strong foundation for Arsenal as they aim to convert domestic success into European glory in 2026‑27.

Germany's World Cup ComebackGermany are desperate for a successful World Cup after two spectacular failures – they were knocked out in the group stages in 2018 and 2022. They certainly look improved under coach Julian Nagelsmann, who took over in September 2023 and has restored some national pride. Germany eased through their World Cup qualification group with five wins from six matches.The Squad: Youth Meets ExperienceThe squad blends the youthful brilliance of Jamal Musiala and Florian Wirtz with the experience of Joshua Kimmich, Antonio Rudiger and veteran goalkeeper Manuel Neuer, who surprised many by coming out of international retirement for the tournament. However, whether the team as a whole is talented enough to pose a serious threat to the favourites and whether all the pieces really fit together under the pressure of a tournament remain to be seen.Group Stage ChallengesIn 2018, Germany crashed out after losing to South Korea. In 2022, they were defeated by Japan en route to being eliminated on goal difference. Nagelsmann has restored some national pride, and Germany looked decent as the host nation at Euro 2024 and were perhaps unlucky to lose to Spain in the quarterfinals. The mood around the squad seems optimistic, and they will expect to go deep in the tournament.Key Players to WatchAt the heart of Germany's ambitions are gifted young attackers in Musiala, Wirtz and Lennart Karl. Musiala, 23, was the standout performer at Euro 2024 and gives the team an individual spark of genius. However, he suffered a horrific injury in July, breaking his leg and dislocating an ankle. Wirtz, meanwhile, has endured a difficult season after his big money move to Liverpool but seems to have found his feet in the Premier League. Karl is another exciting prospect who became Bayern's youngest scorer in the UEFA Champions League and third youngest in the Bundesliga.Neuer's Shock ReturnThe 40-year-old goalkeeper was a surprise inclusion in Nagelsmann's 26-man World Cup squad. Neuer retired from international play after Euro 2024, but the Bayern keeper is now set to make his fifth World Cup appearance with Nagelsmann saying he is the first choice ahead of Oliver Baumann and Alexander Nubel. "Everyone knows the aura and quality Manu has, what he brings to a team," Nagelsmann said as he announced the squad.Questions for NagelsmannSeveral players look nailed on to start – think Leon Goretzka alongside Aleksandar Pavlovic as a double pivot in midfield and Kimmich at right back. But other positions are less settled, not least up front, where Germany lack a world-class out-and-out striker. Niclas Fullkrug is a traditional number nine but did not make the cut after a terrible season in front of goal for AC Milan. Newcastle's Nick Woltemade did make the squad despite a mixed season for his club. Kai Havertz can be used as a false nine, but it is not his most natural position.Group Stage OutlookNo disrespect to the other teams, but Germany will likely have breathed a sigh of relief when the draw for Group E was made. On paper, they will expect to progress comfortably. They open their campaign on June 14 against Curacao, the smallest nation ever to reach a World Cup. Their second game on June 20 against Ivory Coast should provide a stiffer test as the Ivorians, who are returning to the World Cup for the first time in 12 years, are a dangerous side. The final group game is on June 25 against Ecuador, who finished second in qualifying ahead of Brazil, Colombia and Uruguay.Germany's World Cup SquadGoalkeepers: Manuel Neuer (Bayern Munich), Oliver Baumann (Hoffenheim), Alexander Nubel (Stuttgart)Defenders: Joshua Kimmich (captain, Bayern Munich), Nico Schlotterbeck (Borussia Dortmund), David Raum (RB Leipzig), Jonathan Tah (Bayern Munich), Waldemar Anton (Borussia Dortmund), Antonio Rudiger (Real Madrid), Nathaniel Brown (Eintracht Frankfurt), Malick Thiaw (Newcastle United)Midfielders: Jamal Musiala (Bayern Munich), Florian Wirtz (Liverpool), Lennart Karl (Bayern Munich), Angelo Stiller (Stuttgart), Aleksandar Pavlovic (Bayern Munich), Leon Goretzka (Bayern Munich), Leroy Sane (Galatasaray), Felix Nmecha (Borussia Dortmund), Nadiem Amiri (Mainz), Pascal Gross (Brighton and Hove Albion)Forwards: Kai Havertz (Arsenal), Deniz Undav (Stuttgart), Jamie Leweling (Stuttgart), Nick Woltemade (Newcastle United), Maximilian Beier (Borussia Dortmund)

Lead: Marsch’s Final 26‑Man Roster Emphasises Speed and HealthCanadian head coach Jesse Marsch announced a 26‑player squad for the 2026 World Cup, trimming six names and placing a premium on fitness, especially in defence, while keeping attacking talent intact.The Squad Selection Focuses on Speed and HealthIn a primetime TV address, Marsch highlighted speed as the decisive factor, bringing in winger Jacob Shaffelburg as the last addition. The coach explained that the health of key players, notably captain Alphonso Davies, will dictate the team’s performance.The Numbers Behind the Roster26 players selected (3 goalkeepers, 9 defenders, 4 midfielders, 6 attacking midfielders/wingers, 4 strikers)Defensive injuries: Moïse Bombito (broken leg), Derek Cornelius (hamstring), Alfie Jones (ankle ligament)Captain Alphonso Davies – 58 caps, 15 goals for Bayern Munich, still recovering from a muscular issueTop scorer Jonathan David – 75 caps, 39 goals for JuventusGoalkeeper indecision: Maxime Crépeau vs Dayne St Clair, both to share minutes in the first pre‑tournament testImplications for Canada’s 2026 CampaignThe emphasis on fitness aims to mitigate a defence that has missed its first‑choice back four for the past 15 months. With the tournament set to be co‑hosted on Canadian soil, a healthy back line and a fit Davies are seen as essential for a historic group‑stage performance.Offensive concerns remain, as the attack is described as “fully‑healthy but mostly anemic.” Marsch’s confidence in Jonathan David and the revived Cyle Larin will be tested against strong group opponents.Outlook Ahead of the TournamentCanada will face Uzbekistan in Charlotte on Monday, giving both goalkeepers a 45‑minute run‑out. The results will inform the final starting XI for the opening match against Bosnia & Herzegovina. If key injuries resolve, Marsch believes the squad is “the best 26 players this country has ever assembled.”

The LeadA daily pill has shown remarkable results in doubling survival time for patients with pancreatic cancer, the world's deadliest form of the disease. According to clinical trial results presented at the American Society of Clinical Oncology's annual meeting, this breakthrough treatment represents a potential revolution in how we approach a cancer that has seen limited progress for decades.The Breakthrough Drug: DaraxonrasibThe drug in question, daraxonrasib, works by targeting a protein called Kras that fuels nearly all pancreatic cancers. This mechanism represents a significant advancement in treatment strategy, as Kras has been notoriously difficult to target effectively. The drug functions as a Ras(On) multi-selective inhibitor, capable of turning off the Kras protein to stop cancer growth regardless of which variant is present.Impressive Trial ResultsIn the clinical trial involving 500 patients with advanced pancreatic cancer, the results were striking. Those who took daraxonrasib lived an average of 13.2 months, compared to just 6.6 to 6.7 months for patients who received chemotherapy. This represents a near doubling of survival time, with the added benefit of fewer side effects compared to traditional chemotherapy treatments.Industry Impact and Expert ReactionsThe findings have been hailed as a "gamechanger" and "grand slam" by experts in the field. Dr. Rachna Shroff, chief of oncology at the University of Arizona Cancer Center, described the results as "landscape-changing" and "unprecedented survival." When she first read the trial results, conducted by researchers at the Dana-Farber Cancer Institute in Boston, she wept, noting the profound impact this could have on patients after 16 years of treating pancreatic cancer.Dr. Julie Gralow, Asco's chief medical officer, echoed these sentiments, calling the study a "home run" and suggesting it was actually a "grand slam" in terms of its significance.The Ras RevolutionOver 90% of patients with the most common form of pancreatic cancer, pancreatic ductal adenocarcinoma (mPDAC), have a mutation in the Kras gene. This discovery has long been considered the "holy grail" in cancer research, particularly for pancreatic cancer where the mutation is nearly ubiquitous and an early driver of cancer growth.Paula Hanford, chief executive of UK-based Pancreatic Cancer Action, called this one of the most significant developments in treatment she had ever seen. Similarly, Anna Jewell, director of services, research and innovation at Pancreatic Cancer UK, described the results as "exciting," noting that the drug gives patients "months more precious time with their loved ones."Future Outlook and ApplicationsThe success of daraxonrasib opens doors for similar treatments targeting Ras genes in other cancers. Experts at the conference noted that because Ras genes fuel various types of cancer, there is hope for breakthroughs in treating lung and colon cancers as well, with similar drugs already in development for these conditions.However, challenges remain in ensuring these promising treatments become widely available to patients. As Jewell pointed out, tragically half of all people with pancreatic cancer die within just three months of diagnosis, making the rapid implementation of such treatments crucial.

The Lead: Unprecedented Cancer Treatment SuccessDoctors have hailed "unprecedented" trial results that show a triple-action cancer jab can eradicate entire tumours in patients. In an international trial spanning 11 countries, the injection was offered to patients whose cancer had spread or come back and whose disease had failed to respond to other treatments.The Breakthrough: Amivantamab's Triple-Action ApproachThe jab, called amivantamab, shrank the tumours of more than a third of patients, with dramatic changes seen within weeks. In 15 of them, doctors found the drug had melted away their tumours altogether.The smart jab targets cancer in three ways. It blocks both EGFR (epidermal growth factor receptor), a protein that helps tumours grow, and MET, a pathway that cancer cells often use to escape treatment. It also helps activate the immune system to attack the tumour.The Clinical Trial Data: Impressive Response RatesIn the trial, 102 patients with head and neck cancer, the world's sixth most common cancer, were given the jab. Tumours shrank or disappeared completely in 43 patients, including 28 whose tumours shrank significantly and 15 who saw them eradicated entirely.Patients receiving amivantamab lived for a median of 12.5 months overall after starting treatment, despite having a form of cancer with very poor outcomes, once standard treatments stop working.The Impact Analysis: New Hope for Treatment-Resistant CancersKevin Harrington, professor in biological cancer therapies at the Institute of Cancer Research, London (ICR), said: "These are unprecedentedly strong responses in patients whose disease has become resistant to both chemotherapy and immunotherapy. This is a group of patients for whom treatment options are extremely limited, so seeing this level of benefit is very striking."Researchers also highlighted that the trial focused on people with head and neck cancers that did not include those with human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. That is particularly significant, they said, since head and neck cancers not caused by HPV are usually harder to treat, making progress in this group hugely important.The Patient Experience: Transforming Quality of LifeOne of the first patients to benefit was Carl Walsh, 56, who was diagnosed with tongue cancer in May 2024 and joined the OrigAMI-4 trial at the Royal Marsden in July 2025. "I was initially treated with both chemotherapy and immunotherapy, which unfortunately were not successful," he said. "At that point, I was recommended for the OrigAMI-4 trial. I'm now on my 17th cycle of treatment and I'm very pleased with the progress so far."Unlike many cancer treatments, amivantamab is given as a tiny jab under the skin rather than via an intravenous drip, making treatment quicker and more convenient for patients and much easier to deliver in outpatient clinics.The Future Outlook: Expanding Treatment ApplicationsThe results will be presented on Sunday in Chicago at the world's largest cancer conference, the annual meeting of the American Society of Clinical Oncology (Asco).Amivantamab, developed by Johnson & Johnson, is now being evaluated in about 60 clinical trials, primarily for lung cancer, but also for colorectal, brain and gastric cancers.Prof Kristian Helin, the chief executive of the ICR, said: "This study demonstrates how the development of new treatments through rigorous cancer research may lead to meaningful advances, even for patients with very limited treatment options. Achieving this level of tumour response and encouraging survival outcomes in such a challenging-to-treat group represents a significant step forward."

Russell T Davies' New DramaRussell T Davies, known for 'It's a Sin', brings a new culture wars drama to Channel 4. 'Tip Toe' explores the modern state of LGBTQ+ communities, tackling themes of identity and acceptance.Other Highlights9pm, Channel 4: 'Tip Toe', a powerful drama about culture wars in LGBTQ+ communities.9pm, BBC Two: 'The Mother of All Cons', a documentary about a charity backed by One Direction.8.15pm, BBC One: 'Death Valley', a cosy crimer investigating a suspicious death on a TV series set.9pm, BBC One: 'Dear England', a drama about Gareth Southgate and the England football team.10pm, ITV1: 'The Assembly Unseen', a series featuring autistic, neurodivergent and learning-disabled people asking questions of celebrities.Film and Sport10.30pm, BBC One: 'The Nice Guys', a 2016 caper film starring Ryan Gosling and Russell Crowe.7pm, BBC Two: Athletics: Diamond League, live from Rabat, Morocco.

The LeadParis Saint-Germain's second consecutive Champions League victory was marred by violent celebrations as police arrested more than 130 people and deployed thousands of officers to control crowds across the city. The celebrations turned tense with skirmishes between PSG fans and law enforcement, resulting in damaged property and the use of teargas.The Championship Celebration Turns ChaoticMore than 40,000 fans gathered at PSG's Parc de Princes stadium in western Paris to watch the club win its second consecutive title on penalties at the Puskas Arena in Budapest on giant screens. The atmosphere quickly escalated as some PSG fans aimed fireworks at police officers, while others were seen wearing provocative T-shirts and setting fire to Lime Bikes on city streets. Smoke rose from several areas during the clashes as police responded with riot gear and teargas.Security Response and ArrestsBy 11pm local time, police had made more than 130 arrests, with six vehicles and two storefronts damaged during the disturbances. Interior Minister Laurent Nuñez emphasized that authorities had a "very robust, very solid system in place" to curb violence. A police spokesperson stated their responsibility was "to guarantee everyone a festive celebration that is calm and fully secure." France had deployed 22,000 police to maintain order in the capital for the event.A Pattern of Post-ViolenceThis year's celebrations follow a concerning pattern from 2025 when PSG won the Champions League for the first time by beating Inter Milan. That victory resulted in two deaths and close to 200 injuries. Despite increased security measures, the celebrations once again turned violent, raising questions about how the city manages large-scale sporting events and fan celebrations.The Future of PSG CelebrationsAs PSG continues its dominance in European football, authorities will face increasing pressure to find better solutions for managing victory celebrations. The Champs-Élysées boulevard, which was partially cordoned off, saw an estimated 20,000 peaceful supporters, suggesting that while violence occurred, it was not representative of all fans. Future celebrations may require even more sophisticated crowd management strategies to prevent both property damage and potential injuries.

Veteran Stars Flood the 2026 World Cup Squad Lists The expanded 48‑team format has opened the door for a record number of seasoned internationals. Cristiano Ronaldo (41), Lionel Messi (39), Luka Modrić, Edin Džeko, and goalkeepers such as Manuel Neuer and Guillermo Ochoa are all set to feature, creating a roster that could rival the combined total of the previous 22 tournaments. Age Statistics Reveal Record‑Breaking Participation Seven outfield players and goalkeepers are aged 40 or older – the highest ever. The oldest World Cup player on record remains Essam El Hadary (45 years, 161 days in 2018). Goalkeepers dominate the senior cohort: Faryd Mondragón (43) in 2014, Pat Jennings (1986), Peter Shilton (1990), and Ali Boumnijel (2006). Only two outfield players have previously broken the 40‑year barrier: Roger Milla (42 in 1994) and Essam El Hadary. The surge is partly a by‑product of the tournament’s expansion, which allows lower‑ranked nations – such as Cape Verde (ranked 69th) – to qualify, bringing along veteran keepers who might not have made the cut in a 32‑team format. Implications for Team Dynamics and Tournament Competitiveness While experience offers tactical nous and leadership, the physical toll of age is evident. Ronaldo, for instance, still scores and wins aerial duels but lacks the explosive pace that defined his prime. Messi’s occasional brilliance in MLS does not guarantee the same impact against elite European defenses. Teams relying heavily on these stars risk over‑dependence on a dwindling athletic base, potentially hampering overall squad balance. Conversely, the presence of veterans can elevate younger teammates, as seen with Argentina’s Julian Álvarez and Rodrigo De Paul covering Messi’s reduced work‑rate. The trade‑off between mentorship and on‑field effectiveness will shape each nation’s tactical approach. Future of Age and Performance in International Football Advances in sports science – nutrition, recovery protocols, and injury prevention – have extended careers, but the “500‑game rule” still looms for many. Players like James Milner and Robert Lewandowski are already showing signs of wear despite modern conditioning. As leagues worldwide improve medical standards, we can expect more 40‑plus athletes, yet the ceiling for peak performance may remain unchanged. Potential developments include: Greater emphasis on squad rotation and specialized roles for older players. Possible regulatory discussions about age‑related squad limits to preserve competition quality. Increased marketability of veteran icons, driving commercial interest despite on‑field limitations. Outlook: Balancing Experience with Athletic Prime in Upcoming Tournaments For the 2026 World Cup, the gamble is clear: nations must decide whether the tactical acumen of legends outweighs the risk of reduced mobility and stamina. If veteran reliance proves costly, future editions may see a swing back toward younger, high‑tempo squads. However, should seasoned players deliver pivotal moments, the era of the “old‑guard” could solidify, reshaping scouting, contract negotiations, and the very narrative of international football.