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Coordinated strikes by United States and Israeli forces hit Tehran, Isfahan and several other Iranian cities on Tuesday, prompting widespread power outages and extensive damage to civilian sites. The Ministry of Energy confirmed that shrapnel from the raids ruptured a primary power‑transfer line, but the outage was restored within a few hours. Among the most critical targets was the Tofigh Darou pharmaceutical complex in the Karaj industrial zone. The facility, which supplies over 90% of Iran’s domestically produced medicines—including cancer and multiple‑sclerosis treatments—sustained heavy damage from multiple projectiles. In central Iran, Isfahan endured a barrage of heavy bunker‑buster bombs over a nearby mountainous area, likely aimed at military installations. The explosions triggered secondary blasts that illuminated the night sky and produced reverberating shockwaves across the city. North‑west of Tehran, in Zanjan, a building identified as the administrative department of the Hosseinieh Azam religious centre was struck, resulting in at least four fatalities and several injuries. Iranian authorities now claim that more than 2,000 people have been killed by US‑Israeli attacks since the conflict erupted on 28 February, with residential blocks, schools, hospitals and historic sites also affected. Additional targets this week included civilian nuclear facilities, major steel producers, petrochemical plants, and the Iran University of Science and Technology, where an imaging satellite was developed. A professor linked to Iran’s missile programme and his two children were assassinated at their home in northern Tehran. U.S. President Donald Trump reiterated threats to strike Iran’s oil and gas infrastructure, power plants and water‑desalination facilities. Despite the onslaught, the Islamic Revolutionary Guard Corps (IRGC) continues to project defiance. A spokesperson for the Khatam al‑Anbiya Central Headquarters declared that Tehran’s adversaries are “humiliated and on the path of destruction,” while senior commander Ali Fadavi warned that American warships are vulnerable and allegedly transmit false transponder signals. The IRGC also released footage of ballistic missiles aimed at Israel and surrounding nations, and claimed to have downed two U.S. MQ‑9 Reaper drones, promising retaliatory strikes against technology firms linked to the United States and Israel. Domestically, the judiciary announced the execution of two members of the foreign‑based Mojahedin‑e‑Khalq (MEK) group, labeling them terrorists. This follows a series of recent executions tied to the January protests and broader dissent. Authorities also issued new indictments against roughly 200 individuals accused of assisting the U.S. and Israel, including alleged “mercenaries” who disseminated strike footage abroad. Penalties for national‑security offenses now encompass asset confiscation and capital punishment. President Masoud Pezeshkian convened his first cabinet meeting since the war’s onset in a makeshift, blue‑covered space, emphasizing that any peace negotiations will safeguard Iran’s “dignity, security and national interests.” Israel’s Channel 14 reported that Pezeshkian sought greater negotiating leverage with the United States, a request allegedly rebuffed by IRGC chief Ahmad Vahidi.

Israeli participants reportedly sought to carry out a Passover sacrifice within the precincts of the Al‑Aqsa mosque complex, an act that has ignited heightened scrutiny and diplomatic concern.The incident underscores the fragile intersection of religious observance and geopolitical sensitivities surrounding one of the world’s most contested holy sites.

Three Indonesian peacekeepers have been killed in Israeli attacks in Lebanon, according to reports from Al Jazeera. The incident has sparked international concern and condemnation.The peacekeepers were part of a UN peacekeeping mission aimed at maintaining stability in the region. Their deaths underscore the risks faced by peacekeepers in conflict zones.The incident has strained relations between Indonesia and Israel, with Indonesia condemning the attacks. The international community is urging restraint and a return to peace negotiations.

The recent surge in violence in Palestine has resulted in a significant escalation of tensions, with at least 18 people killed in the Gaza Strip and the occupied West Bank. The majority of those killed were victims of Israeli air strikes in Gaza, while a combination of settler and army shootings killed three people in the West Bank.The violence comes as Israel continues to restrict worship at Palestinian holy sites, ostensibly due to the threat of Iranian attacks. The Al-Aqsa Mosque compound has been closed to Muslim worshippers since late February, with authorities extending the state of emergency until mid-April. Additionally, Israeli forces prevented Cardinal Pierbattista Pizzaballa, the Latin patriarch of Jerusalem, from entering the Church of the Holy Sepulchre in occupied East Jerusalem to perform Palm Sunday mass.A global backlash, including soft criticism from United States Ambassador to Israel Mike Huckabee, led to Israeli Prime Minister Benjamin Netanyahu promising “a plan to enable church leaders to worship at the holy site in the coming days”. In Gaza, the week brought a surge in Israeli air strikes and artillery fire, often targeting police forces – a campaign Israeli officials describe as aimed at degrading Hamas’s control over the territory.However, the prospect of reaching the plan’s promised second stage – when reconstruction can begin – appears remote. Instead, the months-long status quo of repeated Israeli strikes on Palestinians in Gaza continues. At least 705 Palestinians have been killed in Gaza since the beginning of the October “ceasefire”, according to the Palestinian state news agency Wafa.Amid heavily restricted aid and stormy weather flooding the tents of hundreds of thousands of displaced Palestinians, humanitarian conditions also continue to deteriorate in Gaza. The Ministry of Health warned on Sunday that fuel and parts shortages for hospital generators threatened to halt medical services entirely.

Eight former premature infants who were airlifted out of al‑Shifa Hospital in November 2023 have been brought back to Gaza, reuniting with their families in Rafah after a humanitarian mission lasting over two years.The children were part of a cohort of at least 25 babies born prematurely who were rescued as Israeli forces stormed the Gaza City medical complex. After receiving critical treatment abroad, the eight toddlers returned accompanied by three relatives and two medical staff, according to the Palestine Red Crescent Society.Hundreds of thousands gathered in Rafah for the emotional reunion. Since the war began in October 2023, the conflict has claimed more than 72,200 lives, including tens of thousands of women and children."Our feelings are indescribable. This is the most important moment in our lives," said Samer Lulu, father of Kinda Lulu, to Al Jazeera. He added that the joy is tempered by the harsh reality of an uncertain future for Gaza’s children.The International Rescue Committee (IRC) warned that the war is reshaping family structures, leaving a growing number of children without parental care. Ulrike Julia, the IRC’s Child Protection Coordinator, emphasized that community‑based care is essential but cannot survive without sustained external assistance.In 2023, the infants were first moved from al‑Shifa to southern Gaza and then evacuated to Egypt for life‑saving treatment. Inside Gaza’s hospitals, doctors faced severe shortages of antibiotics, IV solutions, and even food, supplies that were reportedly blocked by Israeli restrictions.Ola Hijji, mother of toddler Sulaiman Hijji, recalled being forced into a caesarean section at eight months pregnant and losing contact with her child after he was transferred to al‑Shifa’s neonatal intensive care unit. "It’s a beautiful feeling to be reunited," she said.Despite a declared ceasefire in October 2025, Israeli strikes continue near‑daily. The Gaza Health Ministry reported that recent attacks killed over 700 Palestinians and injured many more, including five casualties in a single day of airstrikes across Jabalia and Khan Younis.These reunions underscore the resilience of Gaza’s families while highlighting the urgent need for sustained humanitarian support and a durable path to peace.

More than two years into Israel's war on Gaza, thousands of families remain in limbo, torn between unverified deaths and secret detentions.In a partially destroyed home in Khan Younis, Tahrir Abu Mady clings to the charred walls that echo the memory of her missing children.Her 20‑year‑old daughter, Malak, a university student and volunteer nurse at Nasser Hospital, vanished after briefly returning home with her 18‑year‑old brother Yousef when Israeli ground forces entered the city in 2024.Forensic teams later recovered human remains in the ruined house, prompting Gaza’s Ministry of Health to issue a death certificate for Malak, while Yousef’s fate stayed unknown.The story took a painful turn when a list of Palestinian detainees released by former prisoners included Malak’s name, marked only with “No information available,” reigniting Tahrir’s anguish.Seeking answers, Tahrir tried to hire a lawyer in Umm al‑Fahm to trace her daughter within the Israeli prison system, but prohibitive legal fees made the effort impossible.Human‑rights groups warn that Malak’s case is far from unique. Israeli forces have detained thousands of Gazans in undisclosed locations, often without charge or legal representation.Euro‑Med Human Rights Monitor researcher Maha al‑Husseini estimates around 3,000 people have been forcibly disappeared, many of whom may be dead or imprisoned, with Israeli authorities refusing to provide any information.Families are left in a state of suspended grief, unable to properly mourn or advocate for their loved ones.Today, Tahrir lives between an official death certificate and a name on a smuggled prisoner list, writing on the scarred walls: “We are still waiting for you, Malak … our white coat girl.”

Israeli and U.S. forces launched a series of air strikes on Tuesday that struck Tofigh Daru Research and Engineering Company, one of Tehran’s largest producers of anaesthetics and anti‑cancer medicines. The state‑run firm, owned by the Social Security Investment Company, saw its drug‑production line damaged, according to an official post on X. In the north‑western city of Zanjan, a separate strike hit the Husseiniya Azam, a Shia congregation hall adjacent to a mosque. Iranian Red Crescent teams rescued two people from the rubble; one of the victims died and several others were injured. Further attacks were reported in the western province of Kermanshah, where a civilian contracting company in Qasr‑e Shirin – a border town with Iraq – was hit. One person was killed and eight injured, the Mehr news agency said. Heavy bombing was also confirmed in Isfahan, a strategic hub for Iran’s defence industry and home to key nuclear facilities such as Natanz. Local officials indicated that the strikes may have targeted “military sites,” though the exact locations and damage assessments remain unclear. Iranian officials condemned the operations. Former foreign minister Javad Zarif denounced the targeting of the pharmaceutical plant as a deliberate attack on a medical facility, calling the aggressors “desperate” and accusing them of “diabolical delusions.” Governor‑level security official Akbar Salehi echoed these concerns, noting that the strikes appeared aimed at military installations without specifying which ones. The broader conflict has already claimed 1,937 Iranian lives since the joint U.S.–Israeli campaign began on 28 February, while 20 Israelis have been killed. Recent Israeli interceptions using the Iron Dome and David’s Sling systems have limited damage on Israeli soil, but impact sites were reported in Tel Aviv, Bnei Brak and Petah Tikva. Amid the escalating violence, diplomatic channels remain active. U.S. Secretary of State Marco Rubio told Al Jazeera that communications between Washington and Tehran continue, primarily through intermediaries, and that the U.S. aims to achieve its war objectives “in weeks, not months.” Pentagon chief Pete Hegseth added that negotiations to end the conflict are “very real, ongoing and gaining strength.” Iran’s Islamic Revolutionary Guard Corps (IRGC) claimed a retaliatory strike, saying it hit an Israeli container ship in the Gulf with a ballistic missile and that Iranian drones targeted a group of U.S. Marines near a UAE military base. Public sentiment in Iran has turned sharply hostile, with pro‑state demonstrations erupting in Tehran as citizens protest the continued air raids. The atmosphere, described by Al Jazeera’s Tohid Asadi as a “cloud of mistrust,” reflects growing frustration over diplomatic dead‑ends and the relentless cycle of attacks.

Hundreds of Palestinians took to the streets across the occupied West Bank on Tuesday to voice their opposition to a newly passed Israeli law that allows for the death penalty against Palestinians convicted of deadly attacks. The demonstrations, which were staged in several cities including Ramallah, Tubas, Nablus, Jenin, and Hebron, were organized by prisoner advocacy groups. The protests drew a broad crowd, including families of prisoners, senior members of the Fatah party, civil society organizations, trade unions, and women's groups. More than 9,500 Palestinians are currently held in Israeli prisons, including 350 children and 73 women, with many facing torture, starvation, and medical neglect, leading to dozens of deaths. Israel's Knesset passed the death penalty legislation on Monday evening in a 62-48 vote, with Israeli Prime Minister Benjamin Netanyahu voting in support of the law. The law allows for executions to be carried out by hanging by prison guards appointed by the Israeli Prison Service, with those involved having anonymity and legal immunity. Human rights organizations and Palestinian officials have denounced the law as discriminatory and in breach of international law, as it does not apply equally to Israeli convicts. Amnesty International has called on Israeli authorities to repeal the law, describing it as "a public display of cruelty, discrimination and utter contempt for human rights". The European Union and several countries, including Germany, have also expressed concern over the passage of the legislation, with Germany stating it could "not endorse" the new law and the EU calling on Israel to abide by its previous principled position and obligations under international law.

Iranian news agency Fars reported that the US-Israeli attacks on Isfahan province targeted some military sites. The incident has heightened tensions in the region, with no official confirmation of casualties or damage.In a separate incident, firefighters successfully extinguished a blaze on Kuwait's Al-Salmi oil tanker at the Dubai port following an attack on the fully loaded ship.