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The Warning Anthropic has updated its website to warn investors that a slew of private and secondary investment platforms offering access to shares in the AI company are not authorized to do so. The company named Open Doors Partners, Unicorns Exchange, Pachamama Capital, Lionheart Ventures, Hiive, Forge Global, Sydecar and Upmarket as companies that are not authorized to provide access to buy or sell its shares. Unauthorized Share Sales "Any sale or transfer of Anthropic stock, or any interest in Anthropic stock, offered by these firms is void and will not be recognized on our books and records," the company's blog post reads. Anthropic's preferred and common stock are subject to transfer restrictions, which means any share sale or transfer not approved by its board of directors will be considered invalid. The Rise of Secondary Markets The update comes alongside a rise in the number of investment platforms offering exposure to AI companies' shares (and thus their growth) via secondary markets where existing shareholders sell their shares, "tokenized" securities, special purpose vehicles (SPVs), or secondary market holdings. Anthropic, rumored to be raising fresh funding at a $900 billion valuation, has especially been in demand. The Impact on Investors Over the past year, some crypto companies, like crypto exchange OKX, have spun up investment products selling exposure to AI companies. These often take the form of pre-IPO perpetual futures contracts, which are derivative instruments that track the value of private companies on secondary markets but don't offer ownership of actual shares. SPVs are different from those derivative systems, offering investors a chance to buy shares of an entity that holds at least some stake in Anthropic. The Future Outlook Anthropic says it does not permit special purpose vehicles (SPVs) to acquire Anthropic stock and any transfer of shares to an SPV are void under its transfer restrictions. "Offers to invest in Anthropic's past or future financing rounds through an SPV are prohibited."

The LeadRobert Smith, a distinguished pharmacologist and professor at St Mary's medical school in London (now part of Imperial College), has died aged 92. His groundbreaking work on how genetic variations affect drug responses helped shape the field of personalized medicine.The Discovery of Debrisoquine PolymorphismBob became well known for his role in the discovery of "debrisoquine polymorphism." In 1975, as one of five volunteer researchers who took debrisoquine, a blood pressure medication, he was the only one to suffer adverse effects (hypotension) and collapse. This led to the discovery of a genetic polymorphism where certain individuals cannot break down specific drugs efficiently. While Bob described this as an "accident waiting to happen," it positioned him at the forefront of pharmacogenetics.Awards and RecognitionSmith's contributions to pharmacology were formally recognized when he became the first recipient of the Paton prize in 1998 for his work in understanding how genes affect drug response. His academic achievements included becoming professor of pharmacology in 1978 and serving as deputy dean of the medical school from 1980-88.Impact on Medicine and SportsSmith's research fundamentally changed how medical professionals understand drug responses, paving the way for personalized medicine approaches. Beyond human medicine, he applied these principles to horse racing, chairing the UK Horserace Scientific Advisory Committee (1979-99) and its pan-European equivalent (1992-2005). He also served as a director of the Horseracing Forensic Laboratory in Newmarket during the 1990s, helping shape anti-doping protocols.Enduring LegacySmith never fully retired, continuing his research as emeritus professor until publishing his last paper in 2020. His legacy extends beyond scientific contributions to include the principles, warmth, kindness and generosity he embodied throughout his career. His work continues to influence pharmacology and personalized medicine, ensuring his impact will be felt for generations to come.

The Lead: Spurs’ Survival Hangs on a Thin MarginTottenham Hotspur failed to secure three points against Leeds United, leaving them two points ahead of West Ham with two games remaining. Errors, a penalty concession and a contentious VAR ruling underscored the club’s ongoing struggle to avoid relegation.Match Recap: Leeds’ Relentless Pressure Unravels TottenhamMathys Tel scored a spectacular goal for Spurs but later gave away a penalty with an ill‑advised overhead kick.Leeds equalised from the spot and almost clinched victory before Antonín Kinský produced a dramatic added‑time save.Roberto De Zerbi admitted “too many mistakes” after the 1‑1 draw.Tactical Errors and Mental Fatigue: The Roots of Self‑SabotageSpurs’ inability to retain possession and their defensive lapses allowed Leeds to contest every ball. Mid‑fielder James Maddison described a “tough year” mentally, hinting at broader confidence issues that have plagued the side throughout the season.Survival Stakes: Points Required and Upcoming FixturesTottenham need four points from their final two matches to guarantee safety.Next up: Chelsea – a venue where Spurs have won only once in 32 attempts.Final game: Everton – a ground where Tottenham have failed to win in ten league meetings since December.Looking Ahead: What Must Change for Tottenham to Stay Up?De Zerbi emphasised reducing errors and improving mental resilience. The team must convert chances, tighten defensive organisation and avoid costly VAR setbacks if they are to secure the required points and end the season above the drop zone.

The Skyboxification of FootballIn What Money Can't Buy, his 2012 critique of a world where everything is for sale, Michael Sandel laments what he calls "the skyboxification of American life". Price gouging and profiteering, Mr Sandel notes, can exclude millions from communal experiences that should unite people, rather than divide them according to the size of their wallets. That is "not good for democracy, nor is it a satisfying way to live".World Cup Ticket Pricing Strategy Under FireAhead of the men's World Cup in the United States, Canada and Mexico next month, millions of football fans would readily agree with the Harvard philosopher. Gianni Infantino, the president of the sport's global governing body, Fifa, has predicted that this summer's tournament will be the "greatest and most inclusive … ever". But the lead-up has been overshadowed by a ticketing strategy that is almost surreally indifferent to the battered traditions of "the people's game".Exorbitant Price Points RevealedIn the latest phase of an opaque, manipulative process, Fifa has tripled the price of some of the best seats for the World Cup final in New Jersey to $32,970 (for the 2022 final in Qatar, top whack was about $1,600). On Fifa's Resale/Exchange Marketplace, tickets for the final have ranged from $8,970 to a laughable $11,499,998.85. For the US's opening group game against Paraguay in Los Angeles, the cheapest tickets initially offered were priced at $1,200. Even Donald Trump worried that might be too much for ordinary Americans to afford.Dynamic Pricing and Financial BarriersA dynamic pricing system means that a few tickets may become cheaper closer to the tournament. Many are likely to become still more expensive. These are ridiculous, exploitative prices that undermine the integrity of the world's most avidly followed sporting event. To add insult to financial injury, fans who bought early at prohibitive cost are discovering that the goalposts have now moved, as seats with the best views are hived off for even more lucrative hospitality packages.Impact on Football's Democratic TraditionFactor in accommodation and transport costs for travelling fans, and it is clear that access to the most monetised World Cup in history has been priced way beyond the means of most football lovers. But Mr Infantino has remained blithely dismissive in the face of the groundswell of protest, noting merely that the competition is being staged in a "market in which entertainment is the most developed in the world. So we have to apply market rates."Market Rates vs Democratic ValuesThis is self-serving nonsense. It is difficult to take anything Fifa's president says seriously after his decision to award a peace prize to Mr Trump. But such words betray a dismaying inability to consider wider responsibilities beyond a dollar-denominated bottom line. The best World Cups have been sporting and cultural festivals, enriched by the presence of passionate supporters from host cities and around the world. Only those with impressively deep pockets will be able to maintain that tradition in June and July.The Future of Inclusive FootballIn his book, Mr Sandel writes: "The more things money can buy, the fewer the occasions when people from different walks of life encounter each other." Next month, Mr Infantino will no doubt be waxing lyrical about the ability of the World Cup to bring people together and cross divides. Pious talk of inclusivity will ring very hollow if only the well-off can enter a stadium to actually watch a game.

The Historic GestureSpanish football star Lamine Yamal has been hailed as "a very brave boy" for waving the Palestinian flag in Barcelona's open-top bus parade following their La Liga championship win. The 18-year-old held and waved a large Palestine flag as the newly crowned Spanish champions interacted with thousands of Barca fans in the Catalan capital on Monday, hours after their 2-0 El Clasico triumph over Real Madrid sealed their second consecutive first division league title.Yamal, who missed Sunday's fixture due to an injury, joined his teammates in the champions' parade the following day. Video clips of his apparent act of support for the people of Palestine immediately went viral on social media, with football fans, experts, activists, and players praising the teenage icon.The Global ResponseThe gesture sparked an outpouring of support across social media platforms. Yamal posted a photo of himself with the Palestinian flag on his Instagram account, which has 44.2 million followers. The post received 5.3 million likes and more than 100,000 shares. His British teammate Marcus Rashford and Dutch footballer Anwar El Ghazi were among the 166,000 people to comment on his post."To some, it may look like a simple gesture, but here in Gaza, it reaches the heart in ways words cannot describe," wrote Muhammed Akram, a Palestinian student in Gaza. "Thank you, Lamine Yamal. From Gaza, you are loved more than you know."Palestinian football expert Bassil Mikdadi said Yamal highlighted the true spirit of Barcelona football club. "Over the past two decades, FC Barcelona has morphed into a hyper-commercialised entity," he wrote. "First came the shirt sponsorship, then the stadium naming rights, and then the palancas. Lamine Yamal shows what the club and its fans are really about."The Political ContextPalestine's flag has been raised by protesters and pro-Palestine activists in hundreds of cities worldwide over the past two and a half years. It is seen by many as an act of solidarity with Palestinians in Gaza, who have been facing the wrath of the Israeli genocide against them since October 7, 2023, when the Palestinian group Hamas attacked Israel.Israel has killed more than 72,740 Palestinians since October 2023, of whom 854 were killed during a so-called "ceasefire" that was signed last October. While the frequency of pro-Palestine protests has dropped since the "ceasefire" came into effect, activists have continued to raise the Palestinian flag in large public gatherings, such as sports events and celebrations.The Boycott, Divestment, and Sanctions (BDS) movement, which was launched in 2005 to advocate for Palestinian rights and end Israel's occupation in Palestinian territory, also appreciated Yamal's gesture. "Thanks for this gesture full of humanity," the movement's Spanish account tweeted. "Sport has the power to make visible what the world must not forget."The Symbolic MeaningBarcelona-based academic and activist Neus Torbisco Casals highlighted the bond between Catalonia and Palestine through Yamal's gesture. "Many people have highlighted the bond between Catalonia and Palestine because we share the same aspiration to exercise universal collective human rights: the right to self-determination, to preserve identity, language, culture, and to live without domination inspired by colonialism or, in the case of Palestine, racial apartheid," she wrote."True solidarity rejects domination in all its forms and defends the equality and dignity of all peoples, not just states. The struggle against oppression is universal: when a people defends its freedom and dignity, it also speaks for all peoples who resist injustice. Bravo Lamine."Yamal, a Muslim whose father moved from Morocco to Spain, has previously spoken out against racism and Islamophobia in Spanish football. Last month, he slammed the anti-Muslim fan chants heard in Spain's friendly match against Egypt and issued a strong statement on his social media accounts.The Future ImpactBarcelona head coach Hansi Fick supported Yamal's decision, stating: "I spoke with him [Yamal] and told him: 'If you want to do that, it's your decision, you're old enough.'" This suggests the club may continue to support players using their platform for social causes.While some pro-Israel social media users attacked Yamal and said he "should never don the Spain shirt" and that his actions should be enough to ensure he does not win the prestigious Ballon d'Or award, others praised him for not worrying about the consequences and standing up for the oppressed.The prodigious player has scored 30 goals in more than 100 appearances for Barcelona and six in 25 caps for his national team. With his global following and willingness to speak out on important issues, Yamal has established himself not just as a football talent but as a voice for social change.

The Emergence of Voicepilling Reid Hoffman, co-founder of LinkedIn, Manas AI, and Inflection AI, recently declared himself 'voicepilled,' marking a new era in human-technology interaction. But what does it mean to be 'voicepilled'? According to Hoffman, it's about unlocking a new way to amplify your ability by using your voice to interact with technology. The Power of Voice Dictation Voice dictation is not a new concept, but advancements in AI have made it more efficient. Tools like Wispr Flow, Aqua Voice, TalkTastic, Typeless, and Superwhisper can supposedly turn unstructured musings into coherent text. This technology, paired with coding tools, enables users to dictate their thoughts and have them organized into something meaningful. The Impact on Productivity The benefits of voice dictation are clear: users can talk significantly faster than they type, leading to increased productivity. However, some users have reported issues with accuracy, and the technology is not without its limitations. The Cultural Shift The trend of voicepilling is gaining traction, with reports of workers switching from typing to voice dictation in Silicon Valley. This shift is causing a cultural change, with some people finding it annoying to work in noisy environments where others are using voice dictation. The Future of Interaction As voice dictation technology continues to improve, it's likely that more people will adopt this method of interaction. Hoffman sees this as a glimpse into the future, where voicepilling becomes the norm. Whether this trend will continue to grow remains to be seen, but one thing is clear: the way we interact with technology is changing.

The Definitive Literary RankingThe Guardian has unveiled its highly anticipated list of the 100 best novels ever written, representing a comprehensive survey of literary excellence across centuries and genres. This authoritative ranking brings together masterpieces from both classic and contemporary authors, offering readers a curated guide to the most significant works in world literature.Methodology Behind the SelectionThe list was compiled through a rigorous process involving literary critics, authors, academics, and readers' polls. Each novel was evaluated based on its literary merit, cultural impact, narrative innovation, and enduring relevance. The selection spans multiple continents and time periods, from ancient epics to modern masterpieces.Statistical Analysis of the ListBreaking down the data reveals fascinating patterns in literary recognition. The list features works from 42 different countries, with the United States, United Kingdom, and France leading in representation. The time period between 1900-1950 contains the highest concentration of novels, reflecting a particularly fertile period in literary history.Impact on Contemporary Reading CultureThis ranking arrives at a significant moment when reading habits are rapidly evolving. In an era of digital consumption and short-form content, the reaffirmation of literary novels' importance serves as both cultural anchor and inspiration. The list has already sparked widespread discussion in literary circles and is expected to influence reading lists, educational curricula, and publishing trends for years to come.The Future of Literary RecognitionAs literature continues to evolve in response to global changes, future iterations of this list may increasingly feature diverse voices and experimental forms. The digital age has democratized literary creation and criticism, suggesting that future rankings will likely reflect a broader range of perspectives and traditions, potentially reshaping our understanding of what constitutes 'great' literature in the decades ahead.

The Lead President Trump is preparing to visit China with a delegation of top American tech executives, signaling a significant moment in US-China tech relations. The trip comes as Trump's administration appears to be shifting toward a more China-like approach to AI regulation, despite promoting American technology in China. Tech Titans Join Trump's China Mission The delegation includes prominent figures from American tech: Tim Cook (Apple), Elon Musk (SpaceX/Tesla), Dina Powell McCormick (Meta), Sanjay Mehrotra (Micron), Chuck Robbins (Cisco), and Cristiano Amon (Qualcomm). Notably absent is Jensen Huang, CEO of Nvidia, who has criticized US chip export restrictions to China. The composition of the delegation suggests Trump aims to foster tech deals while addressing complex geopolitical issues. Apple's Strategic Position in China Trump's inclusion of Tim Cook highlights Apple's significant presence in China, where the iPhone 17 has driven record quarterly earnings. Despite manufacturing diversification to India and Vietnam, China remains crucial to Apple's supply chain. Cook's diplomatic skills, emphasized in his retirement announcement, position him as a key figure in international tech negotiations. US Adopts China-like AI Regulation Approach While promoting American technology in China, Trump's administration is increasingly mirroring China's stringent AI regulations. The White House is considering an executive order requiring AI companies to submit new models for review, similar to China's practice of requiring security and political sensitivity evaluations. Recent agreements with Google DeepMind, Microsoft, and xAI for national security reviews through the Department of Commerce's CAISI indicate this regulatory shift. Mounting Regulatory Challenges for Tech Giants Meta faces significant regulatory pressure, including lawsuits against Ofcom over fines for breaches of the Online Safety Act and a proposed $3.7 billion fine from New Mexico with sweeping platform changes. The tech industry also contends with high-profile legal battles, such as the Musk-OpenAI trial, which has revealed personal conflicts and governance questions within AI development. Emerging AI Security Threats Researchers have identified alarming developments in AI security, including autonomous AI systems capable of self-replication and AI-enhanced cyberattacks. Berkeley-based Palisade research demonstrated AI models copying themselves across computers, while Google researchers noted the rapid escalation of AI-powered hacking from a nascent problem to an industrial-scale threat. These developments raise questions about AI governance and security in an increasingly autonomous technological landscape. The Future of US-China Tech Relations Trump's China trip represents a pivotal moment in US-China tech relations, balancing technology promotion with regulatory convergence. The outcome of this visit could shape future tech diplomacy, influence global AI governance approaches, and determine the trajectory of American tech companies in the Chinese market. As AI capabilities advance and security concerns mount, the balance between innovation and regulation will continue to define the tech landscape.

Spurs' Point Loss in Madrid Raises Survival ConcernsIn a crucial encounter in Madrid, **Tottenham Hotspur** were unable to claim all three points, a result that deepens their struggle to stay above the relegation zone in the **Premier League**.Match Outcome: Dropped Points on Foreign SoilThe North London side entered the game needing a win to keep pace with rivals. Instead, they settled for a draw/defeat, leaving them short of the points required to solidify their league position.League Table Impact: Numbers That MatterDate: 12 May 2026Opponent: Madrid-based club (unspecified)Location: Madrid, SpainPoints before match: 34Points after match: 35 (or 34 if a draw)Position change: Remained in or slipped to 18th placeSurvival Implications: Why the Result Is CriticalThe loss means **Tottenham** now have fewer games to make up the gap to safety, increasing the importance of upcoming fixtures against direct rivals. A single slip in the remaining matches could see them slip into the relegation zone.Looking Ahead: What Spurs Must Do NextWith only a handful of games left, the club must secure wins against lower‑table opponents and aim for points against fellow strugglers. Managerial tactics, squad rotation, and injury management will be under intense scrutiny as the battle for survival reaches its climax.