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Israel and the United States have launched a new wave of attacks against Iran, escalating the conflict in the region. The Israeli military confirmed that it carried out a second round of strikes, hours after initiating a wide-scale wave of attacks on infrastructure targets in Tehran. Al Jazeera Arabic's correspondent in Tehran reported that the size and volume of the explosions in the Iranian capital were unprecedented, especially on the eastern side of the city. Iranian air defense systems were activated in response to US-Israeli drones hovering over the city. According to Mohamad Elmasry of the Doha Institute for Graduate Studies, the war is escalating, with US and Israeli forces hitting not only military installations but also hospitals, schools, and over 5,000 residential units. He warned that the situation is becoming increasingly dangerous, especially for the people of Iran. Iran's Fars news agency reported that a strike on a residential building in Khorramabad killed one child and wounded several people, while at least six people were killed in strikes on homes in Tabriz city. The Iranian Red Crescent Society stated that over 80,000 civilian building units have been hit, with some fully demolished. The US military targeted a turbine engine production site in Qom province, used for drone and aircraft components linked to the Islamic Revolutionary Guard Corps (IRGC). Meanwhile, Iranian missile strikes continued overnight in Israel, with falling shrapnel reported across several locations. Iran's Foreign Ministry denied any dialogue with the US, claiming that President Trump's comments aimed to reduce energy prices and buy time to implement military plans. The IRGC warned that if the US targets Iran's power plants, it will hit power plants in areas supplying electricity to US bases and American interests. The conflict has resulted in over 1,500 deaths in Iran and 15 deaths in Israel. The situation has also unsettled oil markets, with prices fluctuating as Asian trading opened. The head of the International Energy Agency warned that the situation in the Middle East is very severe and worse than the two energy crises of the 1970s combined.

The UK government has instructed HS2 Ltd to assess the feasibility of operating its high-speed trains at reduced speeds, aiming to curb escalating costs and facilitate an earlier launch in the 2030s. The proposal involves limiting train speeds to 186mph (300km/h), a significant decrease from the initially planned 224mph. Potentially billions of pounds in savings could be achieved through this adjustment, which would bring the project more in line with typical European high-speed rail standards. Currently, most UK trains operate at a maximum speed of 125mph, while HS1 trains serving Kent and the Channel tunnel reach up to 186mph. Transport Secretary Heidi Alexander has commissioned HS2 Ltd to report back on the potential savings from slower trains before the summer recess. This development follows a review by HS2's new CEO, Mark Wild, who has been working to regain control of the project's costs and delays. Alexander acknowledged the challenges facing the project, stating that previous plans significantly underestimated the work required. Despite these challenges, she praised Wild's leadership and noted that HS2 is now making progress, having completed the excavation of all 23 miles of deep tunnels needed for the initial stage of the railway. The project's overall budget is expected to be reassessed and restated in 2026 prices, with predictions that it will exceed £100bn due to soaring inflation and rising labour and steel costs. As of now, the total expenditure stands at £46.2bn at current prices. Government sources suggest that the original design for the world's fastest railway was “gold-plated” and “needlessly overspecced”, contributing to the cost overruns. Wild emphasized that speed was never the primary objective, and the railway's focus should be on delivering better journeys, increased network capacity, and economic growth.

The US and Iran have been engaged in secretive backchannel talks, mediated by countries such as Egypt, Pakistan, and Oman, in an effort to prevent further escalation of the conflict in the region. The talks, which were denied by Iran initially, may lead to a resolution, but the path forward remains uncertain.According to reports, US special envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi have been in communication, with the Egyptian Foreign Ministry tweeting that conversations were underway on Sunday, 24 hours before Donald Trump's deadline to start attacking Iran's energy infrastructure.The talks have been chaotic, with multiple mediators jostling for the title of peacemaker in chief. Pakistan's army chief, Asim Munir, spoke with Trump on Sunday, while Pakistani Prime Minister Muhammad Shehbaz Sharif held talks with Iranian President Masoud Pezeshkian on Monday.Iran's Foreign Ministry initially denied any talks had taken place, saying: “There is no negotiation whatsoever between Tehran and Washington.” However, the ministry later opened up, with spokesperson Esmail Baghaei saying that messages had been exchanged through friendly countries, indicating America's request for negotiations to end the war.The talks may yield a complete and total resolution in the war, according to Trump, who announced that he was holding off from attacking Iran's energy infrastructure due to the “very good and productive conversations” that had been held with Iran.A 15-point deal has been proposed, including joint control of the strait of Hormuz, no nuclear bombs, and no enrichment of uranium. However, Iran's willingness to agree to abandon its right to enrich uranium remains a major sticking point.If talks fail, Trump warned: “We'll just keep bombing our little hearts out.”

Europe has achieved staggering progress in clean power production, but its efforts are being undermined by a slow transition away from fuel-burning machines. According to Adrian Hiel, director of the Electrification Alliance, the EU has radically transformed its power supply but now needs to focus on increasing the use of electricity in everyday applications.The sluggish pace of electrification has left households exposed to higher bills as the Iran war has driven oil and gas prices to soar. The International Energy Agency has called for a faster shift to electric cars and heat pumps to complement its fuel-saving action plan.Hiel emphasized that high taxes on electricity are a major barrier to the green transition, suggesting that electricity should be taxed like a fresh apple, not like alcohol and tobacco. EU leaders, including Ursula von der Leyen, have acknowledged the need to adjust energy taxes to promote clean air and secure energy.The Electrification Alliance, which includes industry associations like SolarPower Europe and the International Copper Association Europe, is pushing for a faster switch to a decarbonized economy. Hiel noted that the falling cost of clean technology has made it easier for people to ditch fossil fuels, citing his own experience of insulating his home and installing a heat pump and solar panels.Looking ahead, Hiel warned that gas prices are likely to remain high for several years, putting pressure on governments to help households pay their bills and potentially hindering efforts to promote home electrification.

The recent arson attack on Jewish ambulances in London's Golders Green and the escalating violence against Palestinian communities in the West Bank are stark reminders of the dangers of unchecked hatred and intolerance. In Golders Green, a center of Jewish life in London, masked attackers set fire to four ambulances belonging to Hatzola, a volunteer emergency service. This antisemitic hate crime has left the community shaken and highlights the growing concern about safety and security. Meanwhile, in the West Bank, Israeli settlers have been attacking Palestinian villages, torching homes and cars, and forcing families to flee. This cycle of violence is not only devastating for those directly affected but also has far-reaching consequences for the entire region. The author, David Davidi-Brown, argues that these incidents are interconnected by a growing lack of empathy and understanding between communities. He emphasizes that silence in the face of injustice is complicity and that it is essential to challenge hate and violence wherever it occurs. The article also highlights the importance of solidarity and cooperation in the face of adversity. The author cites the example of the Vivian Silver awards, which honor individuals who refuse to give in to hatred and division. The awards were established in memory of Vivian Silver, a lifelong peace activist murdered by Hamas on October 7. Ultimately, the article concludes that we have a choice about how we respond to these incidents. We can choose to let hatred and fear consume us or refuse to let them shape our actions. By refusing to give in to hatred and instead choosing empathy and understanding, we can work towards a more just and peaceful future.

Scientists have made a groundbreaking discovery that could lead to the development of new obesity drugs. By studying the unique metabolic abilities of pythons, researchers have identified a molecule that appears to play a crucial role in regulating appetite and weight loss. The molecule, called pTOS, was found to increase significantly in the blood of pythons after they eat, and when administered to obese mice, it led to a significant reduction in food intake and a 9% loss of body weight over 28 days. The discovery could lead to the development of new obesity drugs that work in a different way to existing medications, such as GLP-1 medications like Wegovy. Unlike these medications, which can have side effects such as nausea and stomach pain, pTOS appears to act on the brain's appetite centers, reducing food intake without these adverse effects. The researchers, led by Dr. Jonathan Long from Stanford University and Prof. Leslie Leinwand from the University of Colorado Boulder, published their findings in the journal Nature Metabolism. They believe that pTOS, which is naturally produced by the snake's gut bacteria and also found in human urine, could be a safe and effective treatment for obesity. While further research is needed before the findings can be applied clinically, the discovery is seen as a promising step towards the development of new obesity treatments. The study's results suggest that pTOS could be a potential therapeutic target for the treatment of obesity and related metabolic disorders.