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Eli Lilly, the US pharmaceutical group behind the Mounjaro weight-loss drug, is seeking to resume its investments in the UK after pausing them last year. The company is in talks with UK ministers to regularly increase NHS drug prices and end a rebate scheme. Patrik Jonsson, president of Eli Lilly's international business, expressed optimism about reaching an agreement this summer.The talks will also explore 'innovative' pricing plans, such as linking payments for anti-obesity drugs to whether the treatment helps patients return to work. This comes as the US pharmaceutical industry increases pressure on the UK, with Keir Starmer agreeing to the first increase in NHS cost-effectiveness thresholds in 27 years. The threshold was raised from £20,000 to £30,000 a year for every year of life gained to £25,000 to £35,000.Eli Lilly was one of several pharmaceutical companies that ditched or paused almost £25bn in planned investments in the UK last year. The company paused its plans to invest in a laboratory site in central London. Jonsson stated that the resumption of Eli Lilly's investment would depend on the outcome of its talks with the government.He emphasized that prices for medicines in the UK had been 'far too low for far too long' and that the threshold couldn't remain static for another three decades. The UK agreed to pay 25% more for new medicines by 2035 as part of a US-UK drug pricing deal, which could eventually reach £9bn a year.Large pharmaceutical companies have protested about a 'rebate' scheme, under which they are required to pay back a chunk of revenue from sales of branded medicines. This scheme is expected to fall in 2026, although Jonsson believes payments 'should actually get down to zero' over time.

Amnesty International has raised concerns that the 2026 Fifa World Cup, set to take place across the US, Canada, and Mexico, may become a 'stage for repression' rather than a celebration of football and unity. The organization published a report titled 'Humanity Must Win,' calling on Fifa and the host countries to take immediate action to protect fans, players, and local communities.The report highlights that while Fifa has promised a tournament where everyone feels safe, included, and free to exercise their rights, the reality on the ground, especially in the US, tells a different story. Amnesty International describes the US as facing a 'human rights emergency' under the Donald Trump administration, marked by mass deportations, arbitrary arrests, and 'paramilitary-style' Immigration and Customs Enforcement (ICE) operations.ICE has announced it will be a key part of the security apparatus for the World Cup, despite concerns over its actions, including the killing of two American citizens by ICE agents in Minneapolis in January. Amnesty International also noted that none of the published US host city plans address how fans or local communities will be protected from ICE operations.The organization pointed out that fans from several countries, including Côte d'Ivoire, Haiti, Iran, and Senegal, face US travel bans, and LGBTQ+ fan groups from England and Europe have expressed concerns about attending matches in the US due to risks to transgender supporters. The report emphasizes that urgent efforts are needed to bridge the gap between Fifa's original promise of a safe and inclusive tournament and the current reality.Fifa stands to earn $11bn from the tournament cycle, but Amnesty's head of economic and social justice, Steve Cockburn, stressed that 'fans, communities, players, journalists, and workers cannot be made to pay the price' for the tournament's success. 'It is these people – not governments, sponsors, or Fifa – to whom football belongs, and their rights must be at the centre of the tournament.'

A commercial court in France has dismissed Cardiff City's claim for £106m in compensation following the death of Emiliano Sala in a plane crash seven years ago. The court found that Nantes, Sala's former team, was not at fault in relation to the flight that resulted in Sala's death.The 28-year-old Argentine player was traveling from France to begin his career with Cardiff City when the single-engine Piper Malibu aircraft crashed into the sea near Guernsey, killing both Sala and pilot David Ibbotson. Cardiff had sought €122m (£106m) for loss of income and other damages from Nantes, claiming the French club was responsible because the flight was organized by an intermediary, Willie McKay.However, the court rejected Cardiff's contention, finding that McKay served as an agent for Nantes but did not organize the flight and was not aware of its illegality. The court also ruled that Nantes suffered moral damage and ordered Cardiff to pay €300,000 to the French club.Cardiff's lawyer, Céline Jones, expressed disappointment with the decision, stating that the club had initiated the process to uncover the truth and show respect for Sala's memory. In contrast, Nantes welcomed the decision, with their lawyer Jérôme Marsaudon saying the club was not responsible for the incident.This ruling follows previous decisions by Fifa and the Court of Arbitration for Sport (Cas), which have also gone against Cardiff in their legal dispute with Nantes. In 2022, Cas ruled that Sala's transfer had been finalized at the time of his death, and Fifa ordered Cardiff to pay Nantes the balance of Sala's transfer fee, amounting to just over €11m out of a total of €17m.

UK savers who want to maximize their cash Isa allowance are being warned not to leave it until the last minute, as the deadline for applications is on Easter Sunday, April 5. The cash Isa allows individuals to save or invest up to £20,000 per tax year, with returns free of tax. Experts are advising savers to take action now, as the allowance for those under 65 will be reduced to £12,000 from the next tax year. This change, announced in last year's budget, aims to encourage younger savers to consider investing in the stock market. In April 2025, a record £14 billion was paid into cash Isas, and this year is expected to see a similar surge. Anna Bowes, personal savings expert at The Private Office, emphasized that savers need to act quickly, as some providers may withdraw their offerings early to process applications before the deadline. Savers can currently find competitive interest rates, with fixed rates of around 4.45% available from providers like Close Brothers Savings, Furness building society, and Vida Savings. For variable-rate Isas, Plum is offering 4.66%, and Tembo Money is paying 4.55%, both including a bonus for the first 12 months. Rachel Springall, finance expert at Moneyfactscompare.co.uk, warned that savers should not delay, as missing the deadline could mean losing the chance to use this year's allowance. She also recommended exploring options beyond traditional high street banks, as challenger banks and building societies are offering some of the best deals.

The UK's retail industry is bracing for the impact of reforms to guaranteed working hours, which could affect over half of retail jobs. The British Retail Consortium (BRC) has warned that the changes, set to take effect from April, may make it harder for shops to employ people, particularly young workers, in part-time roles. The Employment Rights Act will introduce new protections for workers on sick pay, sexual harassment, parental leave, and trade union recognition. Additionally, the act will provide rights to guaranteed hours for those on zero or 'low hours' contracts, flexible working, payment for short-notice cancellation of shifts, and barring fire-and-rehire practices in most circumstances. The BRC, representing major UK retailers, suggests that guaranteed hours protections should only apply to contracts of eight hours a week or fewer, and the reference period to be at least 26 weeks – or ideally a full year. This, they argue, would better reflect seasonal working patterns and ensure reforms address genuine problems without undermining jobs. Helen Dickinson, the chief executive of the BRC, emphasized that flexible retail jobs are vital for millions of people, providing opportunities for students, parents, and those managing health conditions. She warned that if reforms treat flexibility as a problem rather than something workers actively choose, the risk is fewer opportunities and reduced access to work. The BRC noted that 55% of retail roles are part-time, significantly above the UK average of 33%. A survey of 2,000 adults by Opinium for the BRC found that 52% of UK adults think the ability to flex working hours around their lives is important. However, the shop workers' union Usdaw and the TUC have expressed support for the reforms, arguing that they will deliver benefits to those in insecure employment, particularly women and disabled workers, and provide greater job security and predictability for working people.

A pensioner's financial struggles were eased thanks to the kindness of an online stranger. The pensioner had been experiencing issues with his recently purchased second-hand car, which began overheating. Despite visiting multiple mechanics, the problem persisted. The pensioner turned to an online car forum for help, where several users suggested replacing the radiator as a potential solution. However, the carmaker quoted $1,200 for a replacement, which was unaffordable for the pensioner. One forum user, known only by their online handle, recommended purchasing a different type of radiator from an online marketplace for about $150. When the pensioner expressed concerns about buying online, the stranger offered to pay for and ship the new radiator to him. A week later, the radiator arrived, and with the help of a friend, the pensioner was able to install it successfully. The kindness of the stranger not only repaired his car but also restored his faith in humanity. Inspired by the act, the pensioner paid it forward when his town flooded later that year, helping another pensioner fix their water-damaged car. The radiator has continued to run perfectly, and the pensioner's finances have started to recover. The Guardian invites readers to share their own experiences of kindness from strangers, providing a form for submissions on their website.

Los Angeles is saying goodbye to a piece of its history as Taix, a cherished French restaurant in the Echo Park neighborhood, closes its doors for good. The restaurant, which has been a staple of the community for 64 years, will be torn down to make way for a large-scale luxury apartment development. The impending closure has sparked an end-of-an-era frenzy, with lines down the street, packed tables, and loyal fans pinching menus and other memorabilia for their personal collection. Taix, pronounced 'Tex,' has been a de facto museum of a long-gone era of fine dining, offering classic dishes like french onion soup, mussels, and a decadent hamburger. While the restaurant will reopen on the ground floor of the new apartment complex, customers are skeptical that it will retain its historic charm. The current space, a 15,000 sq ft building, is simply too expensive to maintain, with repairs estimated to cost hundreds of thousands of dollars. The Taix family had been using personal savings to cover payroll, but the developer, Holland Partner Group, offered a lifeline with a dollar-a-year rent for the last seven years. The loss of Taix is significant for the Echo Park community, which has been impacted by gentrification. The restaurant has been a hub for creatives, hosting events like 'Gay Guy Night,' and its closure leaves a void in the neighborhood. As one customer noted, 'It’s just gonna be one of those condo buildings, giant, modern condo complexes.' Despite the closure, the legacy of Taix lives on through the memories of its customers, who recall the restaurant's role as a launching pad for nights out, a soft landing spot at the end of one, and a safe space for the LGBTQ+ community. As one regular put it, 'People are the thing that animates the space. Without people, it’s just a building.'

The UK hospitality sector is facing a crisis in confidence, with one in five businesses fearing collapse in the next 12 months. The impending cost crunch has left the sector warning of multiple business failures unless the burden is 'dramatically reduced'.From Wednesday, many pub, restaurant, and hotel companies will face a higher bill for business rates paid to their local authority, while an increase in minimum wage thresholds takes effect on the same day. The survey respondents, who operate more than 20,000 venues, cited increased employment costs as their top worry, followed by business rates and inflation in the cost of food and drink.UKHospitality estimates that the increase in the national living wage and national minimum wage will result in an extra £1.4bn in costs for the sector. The organisation also expects most of its members to pay more in business rates, with the average hotel in England facing a 30% increase worth £28,900, and the average restaurant facing a 15% increase worth £1,800.The sector is calling for the government to dramatically reduce the cost burden, warning that too many businesses are simply not making any money, and that the only result is lost jobs and business closures. 'Hospitality can be a driving force of growth and jobs, but only if its costs of doing business are dramatically reduced,' said UKHospitality in a joint statement with industry bodies.

The Iranian men's national football team made a poignant gesture before their friendly match against Nigeria in Turkey, wearing black armbands and posing with pink and purple school bags with ribbons on them. This powerful display was a tribute to the victims of a devastating air strike on a primary school in Minab, Iran, which occurred on the first day of the Middle East war on February 28. The air strike killed at least 170 people, including students and teachers. The attack happened on the day the United States and Israel launched the war with attacks across Iran. Iran's foreign minister accused the US of a "calculated, phased assault" on the school. According to The New York Times, preliminary findings of a US military investigation indicate that a US Tomahawk cruise missile hit the school due to a targeting mistake. The US military had been bombing an adjacent Iranian base, of which the school building was formerly a part, using outdated data to set the target coordinates. US President Donald Trump initially suggested that Iran itself may have been responsible for the attack, despite the country not having Tomahawk missiles. The incident has added to the tensions between Iran and the US, with Iran qualifying for the World Cup finals this summer but asking for its matches to be moved from the US to Mexico due to concerns over player safety. In the friendly match, Iran lost 2-1 to Nigeria. The team's gesture was a powerful reminder of the human cost of conflict and the impact on innocent civilians, particularly children.