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The LeadPortugal are heading to the FIFA World Cup 2026 on the back of a 2-1 warmup win over Nigeria, but will carry with them some regrets for striker Cristiano Ronaldo. The 41-year-old former Manchester United and Real Madrid star failed to add to his men's-record international haul of 143 goals despite being presented with clear-cut chances with just the goalkeeper to beat in both halves in Leiria on Wednesday.The Match BreakdownThe five-time world player of the year was substituted off in the 65th minute, having been given longer on the field than every other outfield player to start the match for Portugal. Francisco Conceicao, one of the 11 replacements to come on for Portugal, grabbed the 75th-minute winner by cutting in from the right and curling a shot into the far corner. Pedro Neto gave Portugal the lead in the 23rd minute, while Akor Adams equalized for Nigeria 14 minutes later.The Portuguese manager, Roberto Martinez, made eight changes at the break as he attempted to give as many of his squad a chance for playing time as possible. Nigeria's attention will now turn to qualifying for the 2027 Africa Cup of Nations, with the Super Eagles having rested their main two players, Victor Osimhen and Ademola Lookman, for the match following long seasons for their club sides.Ronaldo's PerformanceRonaldo will be making his record-tying sixth appearance at a World Cup, but his performance in this warmup match raised questions about his current form. Despite being presented with clear-cut chances in both halves, the veteran striker was unable to convert, leaving Portugal with some concerns heading into the tournament. The missed opportunities come at a critical time as Portugal prepares to face strong competition in Group K.World Cup ImplicationsPortugal is in Group K at the World Cup with Democratic Republic of Congo, Uzbekistan and Colombia. They begin their campaign next Wednesday against the former in Houston, Texas in the US. That match kicks off at midday local time (17:00 GMT). The win in Leiria follows a 2-1 friendly victory against Chile, suggesting that Martinez's team is finding form at the right time, despite Ronaldo's struggles in front of goal.Upcoming ChallengesFor Portugal, the focus now shifts to their World Cup campaign, where they will face a challenging group that includes Colombia, a team known for their attacking prowess. Roberto Martinez will need to ensure that his squad, including Ronaldo, finds their scoring touch before the tournament begins. Meanwhile, Nigeria's attention will now turn to qualifying for the 2027 Africa Cup of Nations, with the Super Eagles looking to build on their strong performances despite missing the World Cup this time around.

The Contract Extension The Kansas City Chiefs and their starting quarterback, Patrick Mahomes, have agreed to a restructured contract that adds two years to his deal and pushes his total compensation past a half-billion dollars, according to sources. Details of the New Deal Mahomes signed a 10-year, $450m contract in 2020 that set a benchmark not only for the quarterback position but for any NFL player. The latest extension ties the two-time MVP to the Chiefs through the 2033 season, when Mahomes will be 38, and it comes in at $504.75m, with incentives and escalators that could push the value beyond $520m. Financial Impact Mahomes' new deal averages $63.1m per year, surpassing Dak Prescott's $60m average. The contract extension reflects recent market resets for quarterbacks, including deals for Dak Prescott, Jordan Love, Joe Burrow, and Josh Allen. The Impact on the NFL The Chiefs and Mahomes regularly rework his contract in the offseason, giving the team financial flexibility to surround him with talent to compete for championships. This deal sets a new standard for quarterback contracts in the NFL. The Future Outlook Mahomes has won three Super Bowls with the Chiefs and is a two-time league MVP. After undergoing season-ending surgery last December for a knee injury, he has been rehabbing and participated fully in the Chiefs' offseason program.

The US Escalation Against Iran Defence Secretary Pete Hegseth has confirmed that the United States is preparing to launch strikes on 'key facilities' in Iran, framing the attacks as part of the ongoing negotiations for a permanent ceasefire. The Background of the Conflict Hegseth spoke to reporters on Wednesday in Tampa, Florida, as he left the headquarters for the US Central Command (CENTCOM), the military apparatus that oversees operations in the Middle East and parts of Asia. His remarks echoed the escalating rhetoric of Republican President Donald Trump, who warned earlier that Iran would 'have to pay the price' for taking too long with the negotiations. The Imminent Strikes 'CENTCOM — Central Command — will be busy tonight because President Trump said we will be hitting Iran hard, and we will be,' Hegseth said. He explained that he had just reviewed the plans for Wednesday night's attack with Admiral Bradley Cooper, CENTCOM's commander. 'Those strikes that'll happen tonight will be strong. They will be clear,' said Hegseth, who then suggested they may continue into a second day. The Data Analysis Wednesday's attack marks the second straight day of US attacks against Iran, fracturing the fragile truce struck on April 8. The US has been at war with Iran since February 28, when the Trump administration joined Israel in an unprovoked attack on the country. The Impact Analysis The Trump administration has offered contradicting rationales for the war in the months since it began. At one point, US Secretary of State Marco Rubio suggested that the US acted 'pre-emptively' because it 'knew that there was going to be an Israeli action' and it wanted to head off retaliation. Rubio has since walked back those remarks. The Prediction The two sides have differed over issues like the fate of Iran's nuclear programme and whether Iran would receive sanctions relief. Trump has repeatedly threatened to attack Iran's bridges and energy infrastructure, at one point warning that 'a whole civilization will die' as a result of US attacks. Those comments have prompted human rights concerns. Intentionally targeting civilian infrastructure can be considered a war crime, and critics compared Trump's threats against Iranian 'civilisation' to genocidal remarks.

Alien hunters have released fresh guidelines on how to handle potential signals from intelligent life beyond Earth, hoping to avoid panic, misinformation and confusion if any are detected.New SETI Protocols Aim to Manage Alien Signal AnnouncementsThe updated protocols, drafted by a committee chaired by Prof Michael Garrett of the Jodrell Bank Centre for Astrophysics, build on the 2010 guidelines and lay out a step‑by‑step framework for verification, peer‑review, public data release, and media engagement. They stress that researchers must authenticate any candidate signal, submit verification reports for peer review, and make the data openly available while also protecting the personal safety of scientists.Numbers Behind the Update: 2010 Baseline and 15‑Year Social Media Surge2010: Original SETI communication guidelines published.15 years: Explosive growth of social‑media platforms, increasing the risk that rumors of an alien signal could spread rapidly.Implications for Public Trust and Scientific CredibilityBy insisting on transparency and prompt, accurate communication, the protocols aim to rebuild public confidence after past incidents such as the CTA‑102 hoax of 1965 and more recent false claims. Prof Chris Lintott notes that in practice news of a potential signal would likely surface long before certainty is reached, making secrecy impractical and emphasizing the need for an open, collaborative approach.Looking Ahead: How Future Detections Might Be HandledThe guidelines acknowledge that a genuine detection could come from anywhere—from a few thousand light‑years away, which might be “uplifting,” to a signal just outside the solar system, which could be “quite scary.” They provide a template for institutions to engage responsibly with news outlets and social media, while allowing individual researchers to decline public interaction if safety concerns arise. As Steven Spielberg’s upcoming film Disclosure Day highlights the cultural fascination with alien contact, the scientific community now has a clearer, more responsible roadmap for any future discovery.

The Judicial Fallacy of DemeanourImagine a juror on a murder trial, instructed to rely on a defendant's body language to determine guilt. This is not a hypothetical scenario; the UK's judicial system currently advises jurors to observe witnesses' demeanour and mannerisms. In Scotland, courts explicitly direct jurors to look at body language, while in England and Wales, they are warned not to take so many notes that they miss a witness's expressions. This reliance on non-verbal cues is as scientifically dubious as the 1994 case where a jury consulted a Ouija board to determine a verdict, a decision that was eventually overturned.Debunking the Body Language MythosDespite popular belief, the most common cues used to spot a liar are actually the least reliable. Research indicates that liars are often excellent at making eye contact, as they need to monitor the listener's reaction to gauge the success of their deception. Other pervasive myths include the belief that looking to the left indicates lying or that nose scratching betrays guilt. Furthermore, a facial-feature bias exists where attractive defendants are statistically more likely to be found not guilty or receive lighter sentences, proving that appearance often clouds judgment more than any micro-expression.Eye Contact: Liars often maintain intense eye contact to gather feedback.Eye Direction: There is no scientific link between eye direction and truthfulness.Mouth Covering/Nose Scratching: These are not reliable indicators of deception.The Cognitive Load of LyingThe core of the problem lies in the assumption that lying is a physical act. In reality, lying is primarily a linguistic act. Because lying requires significant cognitive effort—simultaneously managing the lie, the listener's reaction, and the adaptation of the story—it leaves the speaker vulnerable to slips in language. Unlike body language, which can be controlled, the structure and selection of words are harder to fake in real-time.Linguistic Cues Over Facial ExpressionsTo accurately detect deception, one must listen rather than watch. Liars often struggle with self-focus, leading to sudden self-corrections where they replace the first-person singular pronoun “I” with the plural “we” to create distance. Additionally, truthful accounts of trauma or dramatic events are rich in sensory-perceptual details (what was seen, heard, or felt), whereas fabricated stories tend to rely on internal thought processes (“I remember thinking”) rather than external sensory input. The future of lie detection lies in analyzing these linguistic patterns rather than relying on unreliable visual cues.

The Ongoing Quest for a Cancer Cure The fight against cancer has seen significant strides in recent years, with better drugs, care, and testing leading to improved survival chances for many patients. According to the World Health Organization, more than 50 million people are alive today after a cancer diagnosis in the last 5 years. However, there is still much work to be done, with many forms of the disease having poor survival rates and uneven access to care globally. Advances in Cancer Research Researchers are working tirelessly to develop new treatments and cures for cancer. The American Society of Clinical Oncology's annual meeting brought together over 40,000 cancer experts to discuss progress on drugs, treatments, and testing. While a magic bullet cure may not be imminent, incremental discoveries are being made, and new treatments are offering hope to patients. Promising New Treatments Several new treatments have shown promise in recent studies. A daily pill has been found to double survival time in a trial of patients with pancreatic cancer, while a new smart drug has been shown to shrink tumors by at least 30% in six of the world's most common cancers. Additionally, weight loss drugs have been found to potentially help prevent and treat cancer, with one study indicating that those who took the drugs were 30% less likely to develop breast cancer. The Road Ahead While these advances are encouraging, there is still much work to be done. A cancer workforce shortage is expected, with a 100 million person shortfall predicted by the middle of the century. Further research is needed to understand the relationship between certain medications and cancer prevention. However, the progress being made offers hope for those affected by the disease, and continued research and innovation will be crucial in the fight against cancer.

The Lead A new study reveals that apitegromab, a drug promoting muscle growth, could significantly reduce the loss of lean body mass when using popular weight-loss medications like tirzepatide (found in Mounjaro). This breakthrough addresses a significant concern with current weight-loss treatments that cause patients to lose muscle along with fat. The Scientific Breakthrough GLP-1 based weight-loss jabs such as Wegovy and Mounjaro have proven highly effective for people who are overweight or obese, but studies show 25-40% of total weight loss comes from reduction in lean body mass – non-fat components including muscle. This matters because lean body mass is important for physical strength, burns more calories than fat tissue, and is linked to a lower risk of type 2 diabetes. Apitegromab works by blocking myostatin, a protein involved in inhibiting muscle growth. In a small trial, researchers in the US randomly divided 102 participants into two groups: 51 received apitegromab alongside tirzepatide, while the other 51 received a placebo with tirzepatide. The Clinical Trial Results After 24 weeks, the trial revealed that total weight loss was similar between the two groups. However, participants given apitegromab alongside tirzepatide lost on average 1.6kg (3.5lb) of lean mass (14.6% of total weight loss), while those given tirzepatide with a placebo lost an average of 3.5kg of lean mass. This means apitegromab was associated with a 55% greater retention of lean mass relative to placebo. The study had limitations, including that most participants were women and the trial was small and short in duration. However, the number of people experiencing side-effects was similar between the two groups, with most deemed to be mild. The Implications for Weight Loss Treatment Prof Alexander Miras, an obesity expert at Ulster University not involved in the work, described the findings as very important. While GLP-1s have been associated with improved "functionality" – making everyday activities easier – they've also been linked to loss in muscle mass and strength. This new medication may help reduce these effects and improve functionality even further. Prof Naveed Sattar, a cardiometabolic medicine expert at the University of Glasgow, emphasized that larger-scale and longer trials are needed to confirm safety and actual health benefits. In the meantime, he recommended that people prescribed weight-loss drugs should be supported to increase physical activity, which can help maintain muscle mass in a physiological way. The Future of Weight Loss Therapies The findings suggest a promising direction for weight-loss treatments that preserve muscle mass while reducing fat. As the popularity of GLP-1 based medications continues to grow, addressing muscle loss could become an important focus for pharmaceutical companies and healthcare providers. Future research will need to confirm the long-term safety and effectiveness of combining apitegromab with weight-loss medications. If successful, such combinations could become standard practice, potentially improving patient outcomes and quality of life during weight loss journeys.

Artists and designers are rallying around a new “anti‑slop” aesthetic as a direct response to the surge of AI‑generated content, a movement that gained visibility after the Runway AI Summit’s showcase of Coca‑Cola’s AI‑driven 2025 Holiday Caravan ad sparked widespread criticism. Runway AI Summit Highlights Coca‑Cola’s Controversial AI Holiday Commercial During the New York‑based summit, Rob Wrubel, co‑founder of Silverside, promoted the Coca‑Cola AI‑generated 2025 Holiday Caravan ad, claiming the entire production could be completed in two weeks. The spot, featuring computer‑rendered polar bears and delivery trucks, was quickly derided by viewers and labeled a “sloppy eyesore” by multiple tech and entertainment outlets. Public Backlash Metrics and Creative Community Response Thousands of creators signed open letters demanding stronger copyright protections against AI scraping. High‑profile musicians announced concerts featuring hand‑scrawled setlists to underline the anti‑AI stance. Several lawsuits have been filed against AI firms for training on artists’ work without permission. Social media threads condemning the Coca‑Cola ad amassed millions of engagements within days. Emergence of the “Anti‑Slop” Aesthetic as a Counter‑Movement Photographer‑designer Michael Schmelling has embraced the trend, creating book covers for Roberto Bolaño’s reissues that mimic high‑school notebook doodles, a style he describes as deliberately “sloppy” yet intentional. Similarly, Stoopid Buddy Stoodios produced a stop‑motion Green Bay Packers video rendered in 1980s‑style action‑figure animation, emphasizing hand‑crafted props and sets. Both projects highlight a shift toward tactile, imperfect visuals that contrast with AI’s polished output. What the Anti‑Slop Trend Means for the Future of Creative Production The movement echoes historical reactions to disruptive technologies, such as the rise of Impressionism after photography became mainstream. By foregrounding the human hand, creators aim to reclaim agency and differentiate their work in an environment where AI can replicate styles at scale. Looking Ahead: Will Hand‑Made Design Reshape the AI Landscape? Industry insiders predict a bifurcated market: AI tools will continue to dominate high‑volume, cost‑driven projects, while a premium niche for handcrafted, “anti‑slop” content will expand, attracting brands eager to signal authenticity. The durability of this niche will depend on consumer appetite for visibly human‑made art and on potential regulatory actions around AI‑generated media.

The ScottishPower Debacle: A Pattern of Insensitivity A recent case highlights ScottishPower's ongoing struggle with handling deceased customers' accounts. A woman, who is the sole executor of her late brother's estate, received a debt collection letter demanding £130 for his gas account, despite informing the company of his death. Meanwhile, the company owed a £430 credit on his electricity account, which it eventually paid with a cheque issued in her late brother's name, rendering it uncashable. Repeated Errors and Lack of Communication The company issued multiple cheques in the name of the deceased, which could not be cashed. Despite numerous emails, ScottishPower eventually informed her that his electricity account would be closed, and it stopped replying to her emails. This is not an isolated incident, as other readers have reported similar experiences of receiving calls, cheques, and letters addressed to the deceased. The Data Analysis: A Trail of Distressing Encounters A newly bereaved widow received letters, emails, and calls from ScottishPower over nine months. A man received a cheque for £312 credit on his late mother's account, made out to her, along with a bill in her name for £191 and a letter promising a £60 refund. A woman received emails from ScottishPower complaining about unpaid direct debits from her late husband's account, weeks after informing them of his death. The Impact Analysis: A Culture of Insensitivity ScottishPower's repeated errors and lack of communication have caused significant distress to grieving relatives. The company's response to these incidents has been inadequate, with promises to review its failings but no concrete actions to prevent similar incidents in the future. The Prediction: Improvement Needed ScottishPower must take immediate action to improve its handling of deceased customers' accounts. This includes updating its records, communicating effectively with relatives, and providing a higher level of care and understanding to those affected. Until then, the company risks facing further criticism and reputational damage.