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Construction site manager Josh Smalls turned a 1960s time‑capsule find into a winning bet on the 2026 Epsom Derby, backing the horse Christmas Day after the note urged a Santa‑Claus‑linked name.Time‑Capsule Note Guides Bet on "Christmas Day"A note and four old coins were uncovered beneath the bust of Sir Joseph Paxton at Crystal Palace Park. The handwritten message explained that the money came from a 1964 bet on Santa Claus and instructed any finder to wager it on a Derby horse whose name could be linked to “Santa Claus”.Bet Stakes, Odds and Potential PayoutJosh Smalls placed a £20 bet.Mayor Christine Harris added a £15 wager, promising any winnings to charity.The horse Christmas Day started at 7‑1 odds.At those odds a combined £35 stake could return roughly £245 before tax.Charitable Boost and Community BuzzThe mayor pledged any profit to Madlani Cancer Support and the Dyslexia Association of Bexley, Bromley, Greenwich and Lewisham, turning a quirky discovery into local goodwill. The win also highlighted the historic link between the park’s regeneration and Britain’s premier Classic race.Will Future Time‑Capsules Influence Betting Strategies?With the “spooky” success story now public, other heritage projects may scrutinise hidden caches for similar clues, potentially adding a new, albeit rare, factor to betting decisions ahead of major races.

The Lead Doctors, scientists, and researchers shared new research about ways to tackle cancer at the 2026 American Society of Clinical Oncology (Asco) annual meeting, the world's largest cancer conference. Breakthroughs in Cancer Treatment The event in Chicago, attended by 40,000 health professionals, featured more than 200 sessions and 2,700 poster presentations on this year's theme, “the science and practice of translation: improving cancer outcomes worldwide”. Smart Drugs in Cancer Treatment Researchers have developed a smart drug that stops cancer cells hiding. The experimental tablet, GRWD5769, can help shrink tumours by at least 30% in six of the world’s most common forms of the disease, delegates in Chicago were told. 26 of 83 patients with cervical, bladder, liver, bowel, lung or head and neck cancers who were given GRWD5769 alongside cemiplimab had tumour reductions of at least 30%. 15 had tumour reductions of at least 30%. A Daily Pill for Pancreatic Cancer A pill that doubles survival time in patients with pancreatic cancer was presented at the conference. In a trial of 500 patients, all of whom had pancreatic cancer that had spread, the pill, daraxonrasib, doubled survival time, with fewer side-effects compared with chemotherapy. Patients who took the drug lived substantially longer, for an average of 13.2 months, compared with 6.6 to 6.7 months for patients who had chemotherapy. Safely Skipping Some Treatments Some patients can safely skip some treatments, according to research presented at the conference. A genomic test could pave the way for a new era of personalised medicine, enabling doctors to determine which patients can safely skip chemotherapy. The Optima trial, led by University College London, followed 4,000 patients with newly diagnosed breast cancer in the UK, Norway, Sweden, Australia, New Zealand and Thailand. Those with a low score on the genomic test could be treated safely with hormone therapy alone. The Future of Cancer Treatment Urgent action is required to cope with rising cancer cases. The world faces a cancer workforce crisis, experts said, with a shortage of 100 million staff expected by 2050 when 100,000 people will be being diagnosed every day. A 21% increase in cancer incidence is predicted, according to a report presented at the conference. The rate is set to rise from 165 per 100,000 people in 2025 to 200 per 100,000 in 2050.

The Life and Legacy of Kanya King Kanya King, the entrepreneur and tireless champion of Black British music who founded the Mobo awards, has died aged 57 from colon cancer. The Battle with Illness The news was announced by the Mobo Organisation, who said she died on Wednesday “after a courageous and characteristically determined battle” with her illness. Tribute to a Fearless Champion “The music world has lost one of its most fearless champions,” the statement continues. “What Kanya created was never simply an awards ceremony. It was an act of cultural justice. Mobo did not just celebrate Black music; it legitimised it, amplified it, and demonstrated its commercial and creative power to a world that had too often chosen not to see it.” Early Life and Career Born to a Ghanaian father and Irish mother in Kilburn, north London, King was working as a TV researcher when she set about filling a gap in the marketplace: an awards ceremony that would celebrate the Black British musicians who were sometimes overlooked by other industry events. The Birth of Mobo She remortgaged her house to raise the money for the first Mobo awards, held in 1996, eventually turning it into an arena-filling event that has celebrated artists such as Stormzy, Dave and Olivia Dean in recent years.

GLP‑1 Medications Show Promise in Reducing Breast Cancer IncidenceRecent analyses presented at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago suggest that patients using GLP‑1 receptor agonists—a class of weight‑loss drugs—experienced a 30% lower likelihood of being diagnosed with breast cancer compared with non‑users.Study cohort: 110,000 women aged 45‑80.Risk reduction: 30% for breast cancer onset.Lead researcher: Dr Elizabeth McDonald, University of Pennsylvania.Adjunctive Use of GLP‑1 Drugs Cuts Breast Cancer MortalityA separate investigation involving 27,000 breast‑cancer patients in Italy reported that adding a GLP‑1 agent to standard therapy was associated with a 30% decrease in cancer‑related death.Institution: IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori, Meldola.Outcome: 30% lower mortality risk.Broad Cancer‑Spread Benefits Observed Across Multiple Tumor TypesData from the Cleveland Clinic, covering 12,000 patients with breast, lung, colorectal or liver cancer, indicated a 38‑50% reduction in progression to stage‑four disease among GLP‑1 users.Study size: 12,000 patients.Risk reduction range: 38%–50% for metastatic spread.Why These Findings Matter for Public Health and OncologyThe consistency of risk‑reduction signals across incidence, mortality and metastasis points to a potential paradigm shift: drugs originally designed for diabetes and obesity may become adjunct tools in cancer prevention and treatment. If confirmed, the impact could be substantial given the prevalence of obesity and the high incidence of breast cancer worldwide.Next Steps: Clinical Trials and Regulatory ConsiderationsExperts caution that the current evidence is observational. Ongoing randomized controlled trials will be needed to disentangle the effects of weight loss from direct pharmacologic actions of GLP‑1 agonists. Regulatory bodies may eventually evaluate these agents for oncologic indications, pending robust trial data.

The Verdict on Richard Gadd's Bleakest Work YetRichard Gadd returns to television with 'Half Man,' a project that stands in stark contrast to the psychological thriller of his previous hit, 'Baby Reindeer.' While the show is technically proficient, the Guardian's review suggests it is so relentlessly bleak and violent that it borders on 'torture pornography.' The article argues that despite the intense performances and clever framing, the show lacks the emotional light required to be considered a success in traditional television terms.A Descent into 'Torture Pornography' and Unrelenting ViolenceThe core of the critique centers on the show's brutality. The protagonist, Ruben, is depicted as a mindless thug whose temper reaches violent peaks, with beatings described as 'numerous and graphic.' The review notes that the show is so dark that even its subplot about a suicidal cancer patient is considered one of its 'least depressing aspects.' The characters are trapped in a cycle of misery and self-medication, creating a viewing experience that is difficult to stomach.Half Man as a Referendum on the Baby Reindeer ControversyA significant portion of the analysis focuses on the show's meta-commentary on the 'Baby Reindeer' controversy. The plot involves a character writing a book about his experiences, leading to a press conference where he is frustrated by journalists demanding to know if it is based on a real person. This serves as a 'right of reply' for Gadd, who was stalked and abused in real life. However, the review suggests this self-interrogation is overshadowed by the sheer unpleasantness of the content.The Future of Dark TV: Is Unpleasantness a Substitute for Substance?The article draws comparisons to other dark series like 'Black Mirror' and 'The Leftovers,' noting that while those shows eventually pivoted to irony or absurdism to alleviate the gloom, 'Half Man' remains trapped in its misery. The review concludes that the show feels like it was made by a '14-year-old emo acting out to get noticed,' contrasting it with 'Adolescence' which is described as a show about men made by men. This raises questions about the sustainability of pure, unyielding despair in modern television.

The Rise of MAHA Moms On April 27, a few hundred protesters gathered in front of the United States Supreme Court in Washington, DC, holding signs with slogans like “How much cancer is acceptable?” and “Monsanto knew”. The protesters were there to support the case Monsanto Company v Durnell, which could make it harder to sue Monsanto’s parent company, Bayer, over allegations that the nation’s most widely used herbicide, glyphosate, causes cancer. The Event Details The protesters, including a handful of newly prominent “MAHA moms” – influencers and grassroots organisers who rallied behind Robert F Kennedy Jr’s presidential run – were seeking to influence decisions on the use of glyphosate and its potential health effects. Glyphosate was, until recently, the key ingredient in the Bayer product Roundup. The company has, to date, settled almost 100,000 such cases, paying about $11bn to plaintiffs. The Data Analysis The MAHA moms, including Kelly Ryerson, known on Instagram as “Glyphosate Girl”, Zen Honeycutt, who runs a group called Moms Across America, and Vani Hari, who goes by “Food Babe” on social media, have been using their influence to pressure lawmakers and shape public opinion on the issue. According to a recent poll by the Kaiser Family Foundation, about 40 percent of Americans say they support the “Make America Healthy Again” movement. The Impact Analysis The MAHA moms’ efforts have had a significant impact, with 73 Republicans joining most Democrats on April 30 to pass a MAHA-aligned amendment to remove liability protections for pesticide companies from the Farm Bill. The vote was a substantial win for a group of influencers who have only become nationally prominent since Trump returned to office. The Prediction While the power of MAHA to drive midterm votes remains unclear, the movement is likely to continue to influence decisions on health and environmental issues. As Ryerson said, “I really, really want to be sure that we keep conservatives on this team. They very much care about this issue.” The MAHA moms’ efforts are likely to have a lasting impact on the debate over glyphosate and its potential health effects.

The Return of a Hip-Hop LegendAdam Yauch AKA MCA's death in 2012 from cancer aged 47 effectively ended the stellar recording and performing career of hip-hop trio Beastie Boys. Since then, bandmates Adam "Ad-Rock" Horovitz and Michael "Mike D" Diamond have made few public appearances but the latter is now back in the fray. His first appearance on a British stage in almost 20 years is in, of all places, a bingo hall in the north east, where he surely becomes the first legendary rapper to yell: "Wassup, North Shields?!"An Unconventional Venue with a Familiar SoundWith turntables on stage, hip-hop clobber in the audience, a six-piece band in matching outfits and bingo tables at the back, this unlikely show feels simultaneously low-key and an event. Mike D is backed by 5D – who include his sons and are more than half his 60 years – whose slamming grooves and crunching guitars aren't Beastie Boys reheated, but certainly have the same inimitable joie de vivre.New Material Takes Center StageRefreshingly and bravely, almost all the setlist is new material, from storming recent single What We Got to an array of tracks from a forthcoming album. Make It Stop doffs a cap to Kraftwerk. True Colours is a huge electronic-rock-rap mashup and the affecting I Don't Care pairs the New Yorker's distinctive reedy wordplay over a hypnotic, minimal groove. There's a loud cheer when Mike D makes a knowing reference to nearby "Newcastle, where the Venom sample comes from," meaning the time the Beasties sampled the geordie metal band on Check Your Head.A Diverse Setlist with SurprisesEvery track sounds different. Crypto samples chinking coins, Switch Up soars over its killer bassline and there's a particularly startling handbrake turn for Thank You, a brilliant ballad in which emotionally sung lines such as "We were just kids, freaking out" seem laden with significance. Late 70s post-punk band Delta 5's Mind Your Own Business makes an unlikely encore before Mike D introduces "something from my own old band", which turns out to be an uproarious So What'cha Want.A Memorable ReturnThere's a chant of "one more song!" to no avail: indeed the only disappointment in this engaging, fun hour-long show is that there isn't any more of it. At 26 Leake Street, London, on 5 and 6 June.

The Rise of Sound Baths Sound baths, a wellness trend where participants lie down or sit while practitioners play instruments like gongs and singing bowls, have become increasingly popular. Proponents claim that these experiences can "soothe and calm your nervous system" and promote "healing" through specific sound frequencies. Can Sound Baths Really Relax Us? Research suggests that sound baths can have a positive impact on mood and stress levels. A 2016 study found that participants who took part in a meditation session involving Tibetan singing bowls reported feeling less tension, anger, and fatigue. Another study linked Tibetan sound meditation to improved cognitive function and mental health in breast cancer patients. The Science Behind Sound and Emotion Experts agree that the effects of sound on wellbeing are largely related to how we perceive and interpret those sounds, rather than specific types or frequencies. Our breathing can synchronise with beats we hear, a phenomenon known as "rhythmic entrainment," and music can induce different emotions such as happiness, sadness, and fear. A Nice Experience or Music Therapy? While sound baths can be a "nice experience," experts caution that they should not be confused with music therapy, a regulated profession that uses music listening or production to improve psychological and physical health. Music therapists work with a range of clients, including in schools and hospitals, and there is no single equivalent regulatory body for sound bath practitioners. The Verdict In conclusion, while sound baths may have some benefits, experts agree that their effects can be overstated. Focusing on one thing and trying to quiet the mind is key to their potential benefits. As with any wellness trend, it's essential to approach sound baths with a critical and nuanced perspective.

The Lead Cancer, a leading cause of death worldwide, is a complex and multifaceted disease. Recent advances in treatment, including a new drug called daraxonrasib for pancreatic cancer, offer hope, but challenges persist. The Event Details Daraxonrasib, a daily pill, has shown promise in doubling the survival time of patients with pancreatic cancer in a 500-person trial. This drug works by targeting a protein called Kras that causes cancer cells to grow and divide. Additionally, a new vaccine, amivantamab, for head and neck cancer has demonstrated effectiveness in shrinking tumors in over a third of patients in a 102-person trial. The Data Analysis Globally, cancer causes nearly one in six deaths, with 10 million deaths annually. While survival rates for some cancers, like melanoma and prostate cancer, exceed 90% in many rich countries, others, such as pancreatic cancer, remain difficult to treat. In the UK, only about one in 20 people with pancreatic cancer survives five years after diagnosis. The Impact Analysis The fight against cancer is hindered by a significant shortage of medical staff. Research estimates a global shortfall of 100 million cancer care workers by 2050, including 65 million nurses and 16 million diagnostic staff. Early diagnosis and rapid treatment are critical, but currently, one in three cancer cases worldwide are undiagnosed, and many cancers are diagnosed at a late stage. The Prediction Despite the challenges, advances in precision medicine and targeted treatments offer a promising future for cancer treatment. As research continues to uncover the complexities of cancer, it is likely that treatment approaches will become increasingly tailored to specific types of cancer and patient populations. However, addressing the global shortage of cancer care workers and improving early diagnosis and treatment are crucial to making progress against this disease.